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Dynamic partition of urban network considering congestion evolution based on random walk

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Chinese Physics B 2025年第1期34卷 530-534页

作者： Zhen-Tong Feng Lele Zhang Yong-Hong wu Mao-Bin Hu School of Engineering Science University of Science and Technology of ChinaHefei 230026China department of Mathematics and Statistics University of MelbourneParkville VIC 3010Australia department of Mathematics and Statistics Curtin UniversityPerth WA 6845Australia

The successful application of perimeter control of urban traffic system strongly depends on the macroscopic fundamental diagram of the targeted *** intensive studies on the partitioning of urban road networks,the dynamic partitioning of urban regions reflecting the propagation of congestion remains an open *** paper proposes to partition the network into homogeneous sub-regions based on random walk *** from selected random walkers,the road network is partitioned from the early morning when congestion emerges.A modified Akaike information criterion is defined to find the optimal number of *** boundary adjustment algorithms are adopted to optimize the partitioning results to further ensure the correlation of *** traffic data of Melbourne city are used to verify the effectiveness of the proposed partitioning method.

关键词： urban road networks dynamic partitioning random walk Akaike information criterion perimeter control

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Enhancement of GAO's Multiparty Quantum Secret Sharing

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Communications in Theoretical Physics 2011年第7期56卷 79-82页

作者： Cheng-Chieh Hwang Tzonelih Hwang Chuan-Ming Li department of Computer Science and Information Engineering National Cheng Kung University department of Information Management Shu-Zen College of Medicine and Management

A multiparty quantum secret sharing (MQSS) protocol with two-photon three-dimensional Bell states was proposed by Gao [Commun. Theor. Phys. 52 (2009) 421] recently. This study points out that the performance of Gao's protocol can be much improved by using the technique of decoy single photons and carefully modifying the protocol to remove some unnecessary unitary operations, devices, and transmissions.

关键词： quantum secret sharing Greenberger-Horne-Zeilinger state

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Shedding light on neurons:optical approaches for neuromodulation

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National Science Review 2022年第10期9卷 34-54页

作者： Shan Jiang Xiang wu Nicholas J.Rommelfanger Zihao Ou Guosong Hong department of Materials Science and Engineering Stanford University wu Tsai Neurosciences Institute Stanford University department of Applied Physics Stanford University

Today' s optical neuromodulation techniques are rapidly evolving,benefiting from advances in photonics,genetics and materials *** this review,we provide an up-to-date overview of the latest optical approaches for *** begin with the physical principles and constraints underlying the interaction between light and neural *** then present advances in optical neurotechnologies in seven modules:conventional optical fibers,multifunctional fibers,optical waveguides,light-emitting diodes,upconversion nanoparticles,optical neuromodulation based on the secondary effects of light,and unconventional light sources facilitated by ultrasound and magnetic *** conclude our review with an outlo ok on new methods and mechanisms that afford optical neuromodulation with minimal invasiveness and footprint.

关键词： optical neuromodulation optogenetics neural interfaces

Abdominal compartment syndrome in patients with severe acute pancreatitis in early stage

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World Journal of Gastroenterology 2008年第22期14卷 3541-3548页

作者： Hong Chen Fei Li Jia-Bang Sun Jian-Guo Jia department of General Surgery Xuan Wu Hospital of Capital Medical University Beijing 100053 China

AIM: To study retrospectively the influence of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in patients with early acute pancreatitis (AP) (during the first week after admission) on physiological functions, and the association of the presence of IAH/ACS and outcome. METHODS: Patients (n = 74) with AP recruited in this study were divided into two groups according to intra-abdominal pressure (IAP) determined by indirect measurement using the transvesical route via Foley bladder catheter during the first week after admission. Patients (n = 44) with IAP ≥ 12 mmHg were assigned in IAH group, and the remaining patients (n = 30) with IAP < 12 mmHg in normal IAP group. For analysis of the influence of IAH/ACS on organ function and outcome, the physiological parameters and the occurrence of organ dysfunction during intensive care unit (ICU) stay were recorded, as were the incidences of pancreatic infection and in-hospital mortality. RESULTS: IAH within the first week after admission was found in 44 patients (59.46%). Although the APACHE Ⅱ scores on admission and the Ranson scores within 48 h after hospitalization were elevated in IAH patients in early stage, they did not show the statistically significant differences from patients with normal IAP within a week after admission (16.18 ± 3.90 vs 15.70 ± 4.25, P = 0.616; 3.70 ± 0.93 vs 3.47 ± 0.94, P = 0.285, respectively). ACS in early AP was recorded in 20 patients (27.03%). During any 24-h period ofthe first week after admission, the recorded mean IAP correlated significantly with the Marshall score calculated at the same time interval in IAH group (r = 0.635, P < 0.001). Although ACS patients had obvious amelioration in physiological variables within 24 h after decompression, the incidences of pancreatitic infection, septic shock, multiple organ dysfunction syndrome (MODS) and death in the patients with ACS were significantly higher than that in other patients without ACS (pancreatitic infectio

关键词： Acute pancreatitis Abdominal compartment syndrome Intra-abdominal pressure Intra-abdominal hypertension Organ dysfunction

Spontaneous superior mesenteric artery dissection following upper gastrointestinal panendoscopy: A case report and literature review

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World Journal of Clinical Cases 2019年第20期7卷 3276-3281页

作者： Chih-Ming Ou Yang Yu-Tong Yen Chai-Hock Chua Chin-Chu wu Kuan-En Chu Tsung-I Hung department of General Surgery Shin Kong Wu Ho-Su Memorial HospitalTaipei 111Taiwan department of Cardiovascular Surgery Shin Kong Wu Ho-Su Memorial HospitalTaipei 111Taiwan department of Radiology Shin Kong Wu Ho-Su Memorial HospitalTaipei 111Taiwan department of Internal Medicine Division of GastroenterologyShin Kong Wu Ho-Su Memorial HospitalTaipei 111Taiwan

BACKGROUND Complications associated with upper gastrointestinal(UGI)endoscopy are uncommon,and rarely involve those of cardiovascular *** report herein a unique case of spontaneous superior mesenteric artery dissection(SMAD)after UGI *** SUMMARY A 45-year-old man who had previously undergone UGI panendoscopy and colonoscopy during a voluntary health check-up at our facility was admitted to the emergency room(ER)at the same facility due to persistent epigastric pain with radiation to the *** the ER,the patient did not present notable abnormalities upon physical,conscious,or laboratory examinations apart from mild tenderness in the epigastric *** abdominal aortic dissection was suspected,and abdominal contrast-enhanced computed tomography confirmed *** was then transferred to the cardiovascular ward and treated conservatively with fasting,prostaglandin E1,and *** patient recovered and returned home soon after,and was symptom-free 6 months after discharge from the *** SMAD after UGI panendoscopic procedure is a previously unreported *** of this complication and associated sequela is warranted.

关键词： Upper gastrointestinal panendoscopy Spontaneous superior mesenteric artery dissection Case report

TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation

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Oncology Research 2025年第1期33卷 161-169页

作者： XIUWANG WEI JIANBO LIANG HUANWEN HUANG DAMING YANG XINXIN WANG XIUJIA WANG CHANGSHENG CHEN KAIQIANG LI TAISEN PANG BIN HU FENGNING wu department of Urology The People’s Hospital of Guangxi Zhuang Autonomous RegionNanning530000China department of Rehabilitation The People’s Hospital of Guangxi Zhuang Autonomous RegionNanning530000China

Background:Transmembrane emp24 trafficking protein 3(TMED3)is associated with the development of several tumors;however,whether TMED3 regulates the progression of prostate cancer remains *** and Methods:Short hairpin RNA was performed to repress TMED3 in prostate cancer cells(DU145 cells)and in a prostate cancer mice model to determine its function in prostate cancer in vitro and in ***:In the present study,we found that TMED3 was highly expressed in prostate cancer *** vitro,shTMED3 treatment suppressed the proliferation,invasion,and migration and promoted the apoptosis of DU145 ***,the Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis showed a strong correlation between TMED3 and forkhead box O transcription factor(FOXO)***,TMED3 inhibition efficiently decreased FOXO1a and FOXO3a *** vivo,TMED3 downregulation suppressed the apoptosis,growth,and metastasis of prostate cancer cells via FOXO1a and ***:The present findings show that TMED3 participates in the regulation of prostate cancer progression via FOXO1a and FOXO3a phosphorylation,thereby revealing a novel mechanism underlying prostate cancer development and suggesting that TMED3 inhibition may serve as a novel strategy for prostate cancer treatment.

关键词： Prostate cancer Transmembrane emp24 trafficking protein 3(TMED3) forkhead box O transcription factor(FOXO) Proliferation Apoptosis

A central limit theorem for square ice

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Acta Mathematica Sinica,English Series 2025年

作者： Wei wu Mathematics department NYU Shanghai

We prove that the height function associated with the uniform six-vertex model(or equivalently, the uniform homomorphism height function from Z2to Z) satisfies a central limit theorem,upon some logarithmic rescaling.

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Glycolytic dysregulation in Alzheimer's disease:unveiling new avenues for understanding pathogenesis and improving therapy

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Neural Regeneration Research 2025年第8期20卷 2264-2278页

作者： You wu Lijie Yang Wanrong Jiang Xinyuan Zhang Zhaohui Yao department of Geriatrics Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Alzheimer's disease poses a significant global health challenge owing to the progressive cognitive decline of patients and absence of curative *** current therapeutic strategies,primarily based on cholinesterase inhibitors and N-methyl-Daspartate receptor antagonists,offer limited symptomatic relief without halting disease progression,highlighting an urgent need for novel research directions that address the key mechanisms underlying Alzheimer's *** studies have provided insights into the critical role of glycolysis,a fundamental energy metabolism pathway in the brain,in the pathogenesis of Alzheimer's *** in glycolytic processes within neurons and glial cells,including microglia,astrocytes,and oligodendrocytes,have been identified as significant contributors to the pathological landscape of Alzheimer's *** changes impact neuronal health and function,thus offering promising targets for therapeutic *** purpose of this review is to consolidate current knowledge on the modifications in glycolysis associated with Alzheimer's disease and explore the mechanisms by which these abnormalities contribute to disease onset and *** focus on the pathways through which glycolytic dysfunction influences Alzheimer's disease pathology should provide insights into potential therapeutic targets and strategies that pave the way for groundbreaking treatments,emphasizing the importance of understanding metabolic processes in the quest for clarification and management of Alzheimer's disease.

关键词： Alzheimer’s disease glial cells glycolysis neuronal metabolism pathogenesis therapeutic targets

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Liver transplantation using an otherwise-wasted partial liver resection graft

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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 29-34页

作者： Yong-Sheng Xiao Yi-Feng He Xiao-wu Huang Zhao-You Tang Jia Fan Jian Zhou department of Liver Surgery & Transplantation Zhongshan Hospital Fudan University

Liver transplantation represents a complex surgical procedure and serves as a curative treatment for patients presenting an acute or chronic end-stage liver disease, or carefully selected liver malignancy. A significant gap still exists between the number of available donor organs and potential recipients. The use of an otherwise-wasted resected liver lobe from patients with benign liver tumors is a new, albeit small, option to alleviate the allograft shortage. This review provides evidence that resected liver lobes may be used successfully in liver transplantation.

关键词： Otherwise-wasted resected liver lobe Partial liver resection graft Liver transplantation Alternative liver transplantation technique Liver resection Benign hepatic tumor Hemangioma Focal nodular hyperplasia