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Spontaneous pneumomediastinum in an elderly COVID-19 patient:A case report

World Journal of Clinical Cases 2020年第16期8卷 3573-3577页

作者： Ning Kong Chen Gao Mao-Sheng Xu Yuan-Liang Xie Chang-Yu Zhou department of radiology The First Clinical Medical College of Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina department of radiology The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310006Zhejiang ProvinceChina department of radiology Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430014Hubei ProvinceChina

BACKGROUND Spontaneous pneumomediastinum(SPM)is more common in young adults,usually caused by external factors like *** causes symptoms such as chest pain or dyspnea,but it is rare to see elderly patients who develop *** we report the case of an elderly patient diagnosed with coronavirus disease 2019(COVID-19)who neither got mechanical ventilation nor had chest trauma but were found to develop SPM for unknown *** SUMMARY A 62-year-old man complained of a 14-d history of fever accompanied by dry cough,shortness of breath,wheezing,myalgia,nausea,and ***-time fluorescence polymerase chain reaction confirmed the diagnosis of *** patient was treated with supplementary oxygen by nasal cannula and gamma *** symptomatic treatments included antibacterial and antiviral *** day 4 of hospitalization,he reported sudden onset of *** day 6,he was *** day 12,the patient reported worsening right-sided chest pain which eventually progressed to bilateral chest *** was diagnosed with SPM,with no clear trigger *** treatment was *** follow-up,the pneumomediastinum had resolved and the patient recovered without other *** We presume that aging lung changes and bronchopulmonary infection play an important part in the onset of SPM in COVID-19,but severe acute respiratory syndrome may represent a separate pathophysiologic mechanism *** the incidence of SPM in elderly patients is low,clinicians should be alert to the possibility of SPM in those infected with severe acute respiratory syndrome coronavirus 2 for life-threatening complications such as cardiorespiratory arrest may occur.

关键词： Aging Spontaneous pneumomediastinum COVID-19 SARS Case report

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Superior mesenteric vessel anatomy features differ in Russian and Chinese patients with right colon cancer:computed tomographybased study

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Chinese Medical Journal 2021年第20期134卷 2495-2497页

作者： Sergey Efetov Jun Jiang Zheng Liu Inna Tulina Valeriia Kim Vladislav Schegelski Kirill Puzakov Roberto Bergamaschi Xi-Shan Wang Petr Tsarkov department of surgery Clinic of Colorectal and Minimally Invasive SurgeryI.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia department of Diagnostic radiology National Cancer Centre/National Clinical Research Centre for Cancer/Cancer HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100021China department of Colorectal surgery National Cancer Centre/National Clinical Research Centre for Cancer/Cancer HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100021China

To the Editor:The literature has registered a considerable interest among Western surgeons in the role of extended lymph node dissection in right *** are a lot of voices of dissent regarding the harvest of nodes lying... 详细信息

关键词： anatomy colon patients

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Identification of potential key molecules and signaling pathways for psoriasis based on weighted gene co-expression network analysis

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World Journal of Clinical Cases 2022年第18期10卷 5965-5983页

作者： Xin Shu Xiao-Xia Chen Xin-Dan Kang Min Ran You-Lin Wang Zhen-Kai Zhao Cheng-Xin Li department of Dermatology The Third Medical Center of Chinese PLA General HospitalBeijing 100039China Chinese PLA Medical School Beijing 100853China department of radiology The Third Medical Center of Chinese PLA General HospitalBeijing 100039China department of Comprehensive Surgical The Second Medical Center of Chinese PLA General HospitalBeijing 100089China department of Endocrine The Third Medical Center of Chinese PLA General HospitalBeijing 100039China department of Dermatology The First Medical Center of Chinese PLA General HospitalBeijing 100853China

BACKGROUND Psoriasis is a chronic inflammatory skin disease,the pathogenesis of which is more complicated and often requires long-term *** particular,moderate to severe psoriasis usually requires systemic *** is also associated with many diseases,such as cardiometabolic diseases,malignant tumors,infections,and mood *** can appear at any age,and lead to a substantial burden for individuals and *** present,psoriasis is still a treatable,but incurable,*** studies have found that micro RNAs(mi RNAs)play an important regulatory role in the progression of various ***,mi RNAs studies in psoriasis and dermatology are relatively ***,the identification of key mi RNAs in psoriasis is helpful to elucidate the molecular mechanism of *** To identify key molecular markers and signaling pathways to provide potential basis for the treatment and management of *** The mi RNA and m RNA data were obtained from the Gene Expression Omnibus ***,differentially expressed m RNAs(DEm RNAs)and differentially expressed mi RNAs(DEmi RNAs)were screened out by limma R ***,DEm RNAs were analyzed for Gene Ontology and Kyoto Encyclopedia of Genes and Genomics functional ***“WGCNA”R package was used to analyze the co-expression network of all mi *** addition,we constructed mi RNA-m RNA regulatory networks based on identified hub mi ***,in vitro validation was *** experimental procedures were approved by the ethics committee of Chinese PLA General Hospital(S2021-012-01).RESULTS A total of 639 DEm RNAs and 84 DEmi RNAs were *** RNAs screening criteria were adjusted P(adj.P)value*** RNAs screening criteria were adj.P value*** functional analysis demonstrated that DEm RNAs were significantly enriched in immune-related biological functions,for example,tolllike recepto

关键词： Psoriasis MicroRNAs Weighted gene co-expression network analysis Functional enrichment MicroRNA-mRNA regulatory network

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Adult Sex Discrimination Using Metric Measurements of Hand Digital Radiographs in Egyptian Population

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Forensic Medicine and Anatomy Research 2022年第2期10卷 27-43页

作者： Ghadeer M. M. Abdelaal Eman A. A. Abdallah Asmaa A. Alshamy Elham Elshawadfy Megahed Forensic Medicine and Clinical Toxicology department Faculty of Medicine Zagazig University Zagazig Egypt radiology department Faculty of Medicine Zagazig University Zagazig Egypt

Objective: The aim of the present study is to discriminate functions for sex determination in a subjected sample of the Egyptian population using the morphology of metacarpals and phalanges for gender comparison. Furthermore, the measurements discussed in this study will aid in predicting the differentiation independently and guaranteeing sex determination in the subjected population individually. Methods: Forty measurements were taken from the right metacarpals and phalangeal bones of 100 subjects, whose ages ranged from 19 to 60. Moreover, the measurements of nine metacarpals and four phalangeal bones were used for sex discrimination in each sample population. Results: Males had significantly greater mean values (P < 0.05) for the lengths of the metacarpals and the proximal phalangeal bones of all right-hand fingers than females. The cut-off value and the accuracy percentage for precise sex classification of males and females using individual and grouped bones showed that a value higher than the marking point classified an individual as male and that a lower value suggested female. Besides, the multiple stepwise discriminant functional analysis of the most predictable internal variables of the metacarpals revealed a cross-validated sex classification accuracy of 100%. In contrast, the most predictable internal variables of the phalanges showed a cross-validated sex classification accuracy of 93%. Conclusion: The results revealed a new forensic suggestion for the determination of sex based on the measurements of the metacarpals and the phalanges. Moreover, various discriminant equations were applied for the declaration of this conceivable recommendation.

关键词： Sex Discrimination Metacarpals Phalanges Osteometric Measurements

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Ultrasomics in liver cancer: Developing a radiomics model for differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma using contrast-enhanced ultrasound

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World Journal of radiology 2024年第7期16卷 247-255页

作者： Li-Ya Su Ming Xu Yan-Lin Chen Man-Xia Lin Xiao-Yan Xie department of Medical Ultrasound The First Affiliated HospitalInstitute of Diagnostic and Interventional UltrasoundSun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)and intrahepatic cholangiocarcinoma(ICC)represent the predominant histological types of primary liver cancer,comprising over 99%of *** their differing biological behaviors,prognoses,and treatment strategies,accurately differentiating between HCC and ICC is crucial for effective clinical ***,an emerging image processing technology,can automatically extract various quantitative image features that may elude the human *** on the application of ultrasound(US)-based radiomics methods in distinguishing HCC from ICC are *** In our retrospective study,we included a total of 280 patients who were diagnosed with ICC(n=140)and HCC(n=140)between 1999 and *** patients were divided into training(n=224)and testing(n=56)groups for *** images and relevant clinical characteristics were *** utilized the XGBoost method to extract and select radiomics features and further employed a random forest algorithm to establish ultrasomics *** compared the diagnostic performances of these ultrasomics models with that of *** Four distinct ultrasomics models were constructed,with the number of selected features varying between models:13 features for the US model;15 for the contrast-enhanced ultrasound(CEUS)model;13 for the combined US+CEUS model;and 21 for the US+CEUS+clinical data *** US+CEUS+clinical data model yielded the highest area under the receiver operating characteristic curve(AUC)among all models,achieving an AUC of 0.973 in the validation cohort and 0.971 in the test *** performance exceeded even the most experienced radiologist(AUC=0.964).The AUC for the US+CEUS model(training cohort AUC=0.964,test cohort AUC=0.955)was significantly higher than that of the US model alone(training cohort AUC=0.822,test cohort AUC=0.816).This finding underscored the significant benefit of incorporating CEUS information in accurately distin-guishing ICC from HC

关键词： Cholangiocarcinoma Hepatocellular carcinoma Contrast-enhanced ultrasound Radiomics Primary liver tumor

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Simulation of 3D Needle-Tissue Interaction with Application to Image Guided Prostate Brachytherapy

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Transactions of Tianjin University 2010年第1期16卷 28-32页

作者：姜杉 HATA Nobuhiko 肖渤瀚安蔚瑾 School of Mechanical Engineering Tianjin University Tianjin Key Laboratory of Advanced Manufacturing Technologies and Equipments department of radiology Brigham and Women's Hospital and Harvard Medical School department of radiology Tianjin Medical University Cancer Institute and Hospital

To improve global control of disease and reduce global toxicity, a complex seed distribution pattern should be achieved with great accuracy during ***, the interaction between the needle and prostate will cause large deformation of soft *** a result, seeds will be misplaced, sharp demarcation between irradiated volume and healthy structures is unavailable and this will cause side effects such as impotence and urinary *** this paper, a 3D nonlinear dynamic finite element simulation method with application to robot-assisted image guided brachytherapy is proposed.A magnetic resonance imaging(MRI) based simulation model is built which considers real patient data, nonlinear material property and interaction between the needle and soft *** sensitivities of seed placement error to the needle insertion point, needle orientation and insertion distance are *** result shows that shorter distance between insertion point and target position with compensation in distance can reduce placement error *** method can be used as a complementary instruction for robot-assisted image guided brachytherapy.

关键词： brachytherapy 软织物有限元素方法动态模拟

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Sarcomatoid carcinoma of the pancreas—multimodality imaging findings with serial imaging follow-up:A case report and review of literature

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World Journal of Clinical Cases 2021年第13期9卷 3102-3113页

作者： Hyun Jae Lim Hye Seon Kang Jeong Eun Lee Ji Hye Min Kyung Sook Shin Sun Kyoung You Kyung-Hee Kim department of radiology Chungnam National University HospitalDaejeon 35015South Korea department of radiology Chungnam National University HospitalChungnam National University College of MedicineDaejeon 35015South Korea department of radiology and Center for Imaging Science Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea department of Pathology Cancer Research InstituteCollege of MedicineChungnam National UniversityDaejeon 35015South Korea

BACKGROUND Sarcomatoid carcinoma of the pancreas is extremely rare and has an extremely poor *** a few cases of sarcomatoid carcinoma of pancreas have been reported,most are focused on a histopathological *** the best of our knowledge,there are no reports documenting multimodality imaging characteristics and chronological changes with emphasis on radiologic *** SUMMARY A 64-year-old woman was admitted to Chungnam National University Hospital with acute ***-enhanced computed tomography of the abdomen revealed a 2.6 cm×2.8 cm multilobular cystic mass in the pancreatic *** pancreatic lesion showed suspected mural nodules and thin ***,mucinous cystic neoplasm of pancreas was *** 7 mo,the patient was readmitted for repeated epigastric abdominal pain and ***-up contrast-enhanced computed tomography of the abdomen and magnetic resonance imaging revealed a marked enlargement(5.4 cm×4 cm),with a predominant internal solid *** mass showed low signal intensity on a T1-weighted image and heterogeneously intermediate high signal intensity on a T2-weighted image. It showed diffusion restriction and peripheral rimenhancement on an arterial phase image, and progressive enhancement on portalvenous and delayed phase images. Distal pancreatectomy was performed. Basedon the morphology and immunohistochemical staining of the specimen,pancreatic sarcomatoid carcinoma was *** present the computed tomography, magnetic resonance imaging, and positronemission tomography computed tomography findings, pathologic features, andchronological changes for preoperative diagnosis.

关键词： Carcinosarcoma Pancreas Computed tomography Magnetic resonance imaging Pancreatectomy Case report

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Chest radiographic characteristics of community-acquired Legionella pneumonia in the elderly

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Chinese Medical Journal 2014年第12期127卷 2270-2274页

作者： Zhang Zhigang Liu Xinmin Chen Luzeng Qiu Jianxing department of Geriatric Medicine Peking University First HospitalBeijing 100034China department of radiology Peking University First HospitalBeijing 100034China

Background Legionella is an important community-acquired pneumonia *** the elderly are especially susceptible to Legionella,few studies have looked at comparative radiographic features of Legionella pneumonia in this *** aim of this study was to explore the chest radiographic characteristics of community-acquired Legionella pneumonia in the *** Serial chest radiographs obtained in 34 patients hospitalized with serologically proven Legionella pneumonia were retrospectively *** x-ray features of an aged group of ≥65 years were assessed and compared with a non-aged group of ＜65 years old with regard to initial patterns and distributions of pulmonary abnormalities,accompanying signs,and *** The most common initial presentation was a patchy alveolar infiltrate involving a single lobe,most often the lower *** was no middle or lingular lobe involvement in the aged group patients,but bilateral pleural effusion was significantly more common in this *** the aged group patients,radiographic progression following adequate therapy,despite a clinical response,was more often noted and the radiographs were less likely to have returned to the premorbid state at discharge,but the differences were not significant between the two *** The discrepancy between imaging findings and clinical symptoms seems more prominent in community-acquired Legionella pneumonia in the elderly.

关键词： Legionella pneumonia radiography elderly

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Contrast-enhanced ultrasound liver reporting and data system for hepatocellular carcinoma diagnosis

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Hepatoma Research 2020年第8期6卷 91-100页

作者： Alexander M.Vezeridis Yuko Kono Interventional radiology Stanford University Medical CenterStanfordCA 94305USA department of radiology Department of MedicineUniversity of CaliforniaSan DiegoCA 92103USA.

Contrast-enhanced ultrasound(CEUS)is a powerful imaging modality for the diagnosis of focal liver lesions,including hepatocellular carcinoma(HCC).The American College of radiology Contrast-Enhanced Ultrasound Liver Reporting and Data System(CEUS LI-RADS®)was created as a standardized reporting system to facilitate consistent and high-quality technique,interpretation,reporting,and data collection for CEUS diagnosis of *** article describes the history and background of CEUS LI-RADS®,its major concepts and algorithm,and the differences between CEUS LI-RADS®and CT/MRI LI-RADS®.

关键词： Contrast-enhanced ultrasound LI-RADS hepatocellular carcinoma diagnosis

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Acute spontaneous thoracic epidural hematoma associated with intraspinal lymphangioma: A case report

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World Journal of Clinical Cases 2021年第14期9卷 3411-3417页

作者： Kai-Jay Chia Li-Han Lin Ming-Tse Sung Tsung-Ming Su Jin-Fu Huang Hsiang-Lin Lee Wen-Wei Sung Tsung-Han Lee Division of Neurosurgery Department of SurgeryKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301Taiwan department of radiology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301Taiwan department of Pathology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301Taiwan department of surgery Chung Shan Medical University HospitalTaichung 40201Taiwan department of Urology Chung Shan Medical University HospitalTaichung 40201Taiwan

BACKGROUND Spontaneous spinal epidural hematoma is a rare neurosurgical *** SUMMARY A 53-year-old healthy woman suffered from complete paraplegia in both legs and loss of all sensation below the xiphoid *** was diagnosed as acute spontaneous thoracic epidural hematoma caused by an intraspinal *** primary lab survey showed all within normal *** of a posteriorly epidural space-occupying lesion at the T4-T8 level of the spinal canal was confirmed on magnetic resonance imaging.A decompressive laminectomy was performed from the T4 to T7 levels at the sixth hour following abrupt onset of complete *** lesion was confirmed as *** patient recovered well within one *** This study reports a case of acute spontaneous thoracic epidural hematoma caused by an intraspinal lymphangioma with well recovery after surgical intervention.

关键词： Lymphangioma Epidural hematoma Intraspinal Paraplegia Decompressive laminectomy Case report

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