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The Role of Baseline Functional MRI as a Predictor of Post-Stroke Rehabilitation Efficacy in Patients with Moderate to Severe Upper Extremity Dysfunction

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Journal of Behavioral and Brain Science 2022年第12期12卷 658-669页

作者： Reza Almasi Ghaleh Sarvenaz Rahimibarghani Niloofar Shirzad Ailar Ahangari Mohammad-Reza Nazem-Zadeh Abolfazl Mahmoudi Aqeel Abadi Abbas Tafakhori Hamid R. Fateh Physical Medicine and Rehabilitation department Shariati Hospital Tehran University of Medical Science Tehran Iran Medical Physics and Biomedical Engineering department Research Center for Molecular and Cellular Imaging Advanced Medical Technologies and Equipment Institute Tehran University of Medical Sciences Tehran Iran Neurology department Iranian Center of Neurological Research Neuroscience Institute Imam Khomeini Hospital Tehran University of Medical Sciences Tehran Iran Neuromuscular Research Center Tehran University of Medical Sciences Tehran Iran

Introduction: Upper extremity impairment is one of the common complications following a stroke. There are numerous rehabilitation strategies to address this problem. However, patients with moderate to severe upper limb disabilities respond differently to the same rehabilitation protocol. Apart from each patient’s unique characteristics, there are specific brain reorganizing patterns that affect the post-rehabilitation response rate. Functional magnetic resonance imaging (fMRI) determines brain activation area and connectivity patterns and has been utilized in the neurorehabilitation field. Material and Methods: Six stroke patients who suffered from moderate to severe upper extremity dysfunction were enrolled in this pilot study. Upper extremity function tests including the Fugl-Meyer assessment test for upper extremity (FMA-UE), and Wolf Motor Function Test (WMFT) were utilized before and after completing an intensive rehabilitation. The intensive rehabilitation program was conducted one hour a day for five days per week for four weeks. Moreover, fMRI was applied before initiating rehabilitation. The regions of interest were those associated with movement, including Brodmann areas (BA) BA1-BA6. Results: Six stroke patients in the sub-acute to chronic phase and ages ranging between 33 - 75 years were enrolled. All patients showed an improvement in upper limb function after four weeks of rehabilitation. Patient number one (Pt1) had the most improvement in FMA-UE, while patient number four (Pt4) recovered the most measured by WMFT. Pt1 demonstrated increased activity in all contralesional regions, whereas Pt4 had only increased activity in ipsilesional areas. Furthermore, patients with greater activation in the ipsilesional BA6 (Pt1, Pt4, Pt5, and Pt6) had better responses to the rehabilitation therapy. Conclusion: Patients with greater activation in the baseline fMRI, particularly ipsilesional BA6, had a better response to the intensive rehabilitation therapy. However

关键词： Stroke Functional MRI Rehabilitation Upper Extremity

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强烈淬火:改善了硬度和残余应力(英文)

金属热处理 2007年第5期32卷 84-89页

作者： N.I.Kobasko G.E.Totten L.C.F.Canale Intensive technologies Ltd department of Mechanical and Materials Engineering Portland State University Departamento de Materiais Automovilistica e AeronáuticaEESC-Universidade de So Paulo

通过数值模拟和试验研究结果确定使用强烈淬火方法在表面形成最佳压应力,根据这些结果,提出了改善零件的热处理和设备的一些建议。除了探讨最大表面压应力的形成外,对使用可控淬透性钢的优点也进行了讨论。

关键词：强烈淬火残余应力表面压应力硬度数值模拟热处理淬透性面形

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浙江大学特种控制阀研究室（英文）

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2019年第3期20卷 229-232页

作者： Jin-yuan QIAN Bao-qing LIU Zhi-xin ZHANG Sun-ting YAN Li-long CHEN Zhi-jiang JIN Institute of Process equipment College of Energy EngineeringZhejiang University State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang University department of Energy Sciences Lund University Hangzhou Worldwise Valve Co. Ltd.

目的:目前大中型控制阀大多存在结构复杂、驱动能耗大、反应时间慢、振动噪声大、稳定性差和使用寿命短等缺点。基于此,浙江大学相关研究人员组建了特种控制阀研究室,致力于提升控制阀的整体性能和设计水平。研究点:本研究室的主要方向... 详细信息

目的:目前大中型控制阀大多存在结构复杂、驱动能耗大、反应时间慢、振动噪声大、稳定性差和使用寿命短等缺点。基于此,浙江大学相关研究人员组建了特种控制阀研究室,致力于提升控制阀的整体性能和设计水平。研究点:本研究室的主要方向为:1.控制阀内部流动特性分析和新结构设计开发;2.流体目标流量、温度、压力和振动噪声等的智能控制研究;3.适应纳米流体、压缩氢气和高温高压过热蒸汽等新流体介质的智慧控制阀研究。展望:特种控制阀作为超超临界火电机组、核电、石化高压反应和百万吨级乙烯工程等国家重大重点工程的关键零部件之一,将会在内流动机理、新结构开发、新流体介质和智能控制等研究领域得到广泛关注和长足发展。

关键词：控制阀智能控制流动控制流动特性

Electrostatic Charge Generation in Pneumatic Conveying Process: Effect of Particle Properties

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Journal of Power and Energy Engineering 2019年第6期7卷 1-11页

作者： Manoochehr Fathollahi Mohammad Eghbal Ahmadi Seyed Mohammad Javad Hosseini department of Material and Manufacturing technologies Malek Ashtar University of Technology Tehran Iran department of Chemical and Petroleum Engineering Sharif University of Technology Tehran Iran

One of the main concerns in particle pneumatic conveying process is the possibility of hazards for operation safety due to the electrostatic charge generation as a result of collisions between particles and the equipment wall. Indeed, the electrostatic discharge can occur in the equipment leading to fire or explosion. Simulation of these kinds of processes plays an important role in understanding the various aspects of the system in order to production loss prevention. This paper deals with the simulation of particle pneumatic conveying process inside an inclined tube using a particular method. In this method, the electrification of particles inside the tube is influenced by the vertical collision velocity against the tube wall. Simulation of the particle movements inside the tube, generation of electrostatic charges over the particle surfaces as well as the possibility of fire as a result of discharging the electrostatic energy are investigated. The possibility of fire is investigated by comparing the amount of electrostatic energy with minimum ignition energy (MIE) of the particles. The effect of particle properties including the size and mechanical ones in the simulation is studied. Finally, several solutions are proposed to manage the risk of fire and explosion. As results, the electrostatic energy (E) is beyond the MIE, and the electrostatic discharge can occur leading to explosion for the diameters more than 2 mm and also for elasticity constants lower than 140 MPa. Eventually, there is no hazard of fire and explosion, since all calculated electrostatic energy for the change of Particle Poisson’s ratio varying from 0.1 to 0.9 is less than the MIE value for the air flow rate of 10 m3/h.

关键词： Electrostatics Pneumatic Conveying Simulation Powder Technology Particle Charge

The lived experience of family caregivers caring for patients dependent on life-sustaining technologies

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International Journal of Nursing Sciences 2018年第4期5卷 365-369页

作者： Waraporn Kongsuwan Pongpaka Borvornluck Rozzano C.Locsin Adult and Elderly Nursing department Faculty of NursingPrince of Songkla UniversityHat YaiSongkhla90112Thailand Medical equipment Center Department of NursingSongklanagarind HospitalFaculty of MedicineHat YaiSongkhla90112Thailand Institute of Biomedical Sciences Tokushima University Graduate SchoolTokushimaJapan Florida Atlantic University Boca RatonFL33431USA

Purpose:The purpose of this study was to describe the meaning of the lived experience of family caregivers caring for their loved ones who were dependent upon life-sustaining technologies while in the ***:This study followed van Manen's hermeneutic phenomenological approach to generate and analyze data to describe the experience of ten family caregivers who met the following inclusion criteria:a family member who participated actively in caring for the loved one who was dependent upon technologies for human *** were collected using individual in-depth *** interview transcriptions were analyzed using van Manen's phenomenological approach,while Lincoln and Guba's criteria were used to establish trustworthiness of the ***:Four thematic categories structured the meaning of the experience:Being an invisible person;supporting patients'wholeness;struggling to trust technologies for human care;and living in *** thematic categories were reflective of Van Manen's four lived worlds of body,relation,space,and ***:Understanding the experience of family caregivers challenges nurses to express their technological competencies in caring more fully in their human ***'s theory of Technological Competency as Caring in Nursing was used to explain and describe the meaning of the experiences of family caregivers caring for patients who were dependent upon technologies for human care,and foster nursing practice as caring in nursing.

关键词： Caring for Family caregivers Phenomenology Technological competency

Improving the Thermal Stability of Cu_3N Films by Addition of Mn

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Journal of Materials Science & Technology 2015年第8期31卷 822-827页

作者： Xiaoyan Fan Zhenjiang Li Alan Meng Chun Li Zhiguo Wu Pengxun Yan Advanced Optoelectronic Materials and technologies Engineering Laboratory of Qingdao School of Mathematics and PhysicsQingdao University of Science and Technology Key Laboratory of Polymer Material Advanced Manufacturing Technology of Shandong Province Qingdao University of Science and Technology College of Chemistry and Molecular Engineering Qingdao University of Science and Technology department of Physics Ocean University of China School of Physical Science and Technology Lanzhou University

Mn-doped Cu3N films were deposited by cylindrical magnetron sputtering equipment on the common glass at room temperature. The incorporation of Mn can change the preferred growth orientation from Cu-rich plane （111） to N-rich plane （100） due to the improvement of nitridation of Cu. The shrinkage of the lattice and the X-ray photoelectron spectroscopy results reveal that Mn should replace Cu atoms in the lattice or be segregated in the grain boundaries. The thickness of Mn-doped film is smaller than that of the pure one due to the less physisorption of N species among the columnar grains. The mean grain size and the energy gap become larger with increasing Mn concentration to 2.2 at.% and then decrease when the concentration of Mn is higher than 2.2 at.%. Notably, weak doping of 1.5 at.% Mn successfully promotes the decomposed temperature by -50℃. According to the results of XRD and SEM for Mn- doped films annealed in vacuum, a possible decomposed mechanism with increasing the annealing temperature is proposed.

关键词： Magnetron sputtering Cu3N film Mn-doped Thermal stability

High-voltage Nanosecond Pulse Generators of the ＂PROTEUS＂ Line for Discharge with Runaway Electrons Applications

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高电压技术 2013年第10期39卷 2506-2513页

作者： Anatoly N. Maltsev Maxim V. Martynov Alexey V. Mikov Viktor G. Podkovyrov Leonid L. Zhukov Alexander Yu. Ivanov Institute of Atmospheric Optics Russian Academy of Sciences Tomsk 634021 Russia Electrodynamic Systems & technologies LLC Tomsk 634021 Russia Institute of High-current Electronics Russian Academy of Sciences Tomsk 634021 Russia

Many applications of gas discharge with runaway electrons (DRE) require high-voltage pulse generators (HVPG) with very high increasing rate of output voltage (up to 100 kV/ns), long operation life and low cost. Such HVPGs have to be controlled by external computer for working in combination with other modern equipment. In this paper, some HVPGs development for DRE application in industry and medicine are described. The functional structure and operation principles are discussed for the HVPG of "PROTEUS' line. It is shown that on different loads, the "PROTEUS" generators can produce high-voltage nanosecond pulse with energy up to 1 J, output voltage amplitude from zero to 150 kV, and pulse repetition frequency from zero to 2 000 Hz. Four models of the "PROTEUS" generators are described. The output voltage leading front duration is 150 ns for the "PROTEUS-I" model, 10-20 ns for the "PROTEUS-II", 2 ns for the "PROTEUS-IH" and 0.5 ns for the "PROTEUS-IV". DRE parameters obtained by using "PROTEUS" HVPGs are demonstrated. Some results of DRE application in solid-state surface modification of natural textile and polymer films are shown as well.

关键词： PROTEUS 纳秒脉冲发生器电子应用气体放电高压失控输出电压脉冲重复频率

Microbiological, Physico-Chemical and Organoleptic Parameters of Apple Juice, Processed by Shungite

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Journal of Food Science and Engineering 2013年第9期3卷 489-495页

作者： Melnyk Lyudmila Bessarab Oleksandr Matko Svitlana department of Fermented Canning and Sugar Productions National University of Food Technologies City of Kyiv O1601 Ukraine

This paper is dedicated to results of studying microbiological, physico-chemical and organoleptical parameters of apple juice processed by shungite. Shungite is a natural mineral which has special structural composition, characterized by the existence of fullerenes and nanotubes. This paper explains the methods applied by the authors to prepare shungite for experimental research, to process apple juice by adsorbent, to determine the quantity of microorganisms in juice after it interacted with shungite, weight percentage of dissolvable dry solids, active acidity and quality parameters. In juice, processed by shungite, bacteria, fungi and yeast were detected. The authors made a comparison between microbial population in juice before and after its interaction with shungite. The paper refers to method under which shungite adsorbs bacteria, fungi and yeasts. The authors presented the results of studying dry solids content, active acidity of apple juice, processed by shungite at various temperatures and conducted assessment of apple juice quality after its interaction with sorbent. Through their research, the authors established rational parameters of apple juice processed by shungite under which the maximum reduction of microbial insemination is reached. The research proved that after apple juice interacts with shungite, its dry solids content and active acidity level remain unchanged. This paper confirmed high quality parameters of apple juice processed by shungite. Taking into account the obtained results, the authors concluded that use of shungite to process apple juice does not require expensive equipment, complex maintenance of the processing procedure, which reduce the cost value of a manufactured product.

关键词： Apple juice shungite adsorptive processing microorganisms quality parameters.

Iron-catalyzed[4+2]annulation of amidines with α,β-unsaturated ketoxime acetates toward 2,4,6-trisubstituted pyrimidines

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绿色合成与催化(英文) 2023年第2期4卷 150-153页

作者： Qinghuan Wu Luchao Li Binyan Xu Jie Sun Dong Ji Yuguang Li Lei Shen Zheng Fang Jindian Duan Beining Chen Kai Guo College of Biotechnology and Pharmaceutical Engineering State Key Laboratory of Materials-Oriented Chemical EngineeringNanjing Tech UniversityNanjing 211816China Institute of Nanjing Advanced Biomaterials&Processing equipment Nanjing 211299China department of Chemistry University of SheffieldSheffield S37HFUK

An iron-catalyzed[4+2]annulation of amidines with α,β-unsaturated ketoxime acetates is *** strategy employs amidines as CN units and provides a new protocol for the construction of 2,4,6-trisubstituted pyrimidines under batch and continuous flow conditions in moderate to good yields,exhibiting good functional group tolerance,scalability and operational simplicity.

关键词： Annulation Amidines Ketoxime acetates Pyrimidines Iron