检索结果-南通市图书馆

Hepatobiliary & Pancreatic Diseases International 2023年第2期22卷 213-216页

作者： Jian Cheng De-Fei Hong Cheng-Wu Zhang Xiao-Ming Fan Zu-Yan Luo Wei-Feng Yao Li-Ming Jin General surgery Cancer CenterDepartment of Hepatobiliary&Pancreatic Surgery and Minimally Invasive SurgeryZhejiang Provincial People’s HospitalAffiliated People’s Hospital of Hangzhou Medical CollegeHangzhou 310014China department of General surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310020China

To the Editor: Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) promotes the future liver remnant(FLR) rapid proliferation in the short term, which in turn provides an opportunity for... 详细信息

关键词： hepatocellular liver microwave

Local Inhibition of Chlorhexidinum on Lewis Pulm onaryCarcinom a in Mice

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 1999年第3期19卷 223-225页

作者： XIONG Jiongxin , HUANG Tao QIU Dengbo department of General surgery, Xiehe Hospital, Tongji Medical University, Wuhan 430022 department of General surgery Xiehe Hospital Tongji Medical University Wuhan 430022

C 57 inbred mice ( n =100) were employed to develop animal models of Lewis pulmonary carcinoma. The study on the tumor inhibition was performed by infiltrative injection of 3.5 % Cy or chlorhexidinum of two different concentrations around the tumor respectively. The survival, survival rate, tumor growth rate, and pulmonary metastasis node number were compared. The results showed that the inhibitory effects of 0.1 % and 0.5 % chlorhexidinum were the same as that of 3.5 % Cy, but the toxic and side effects were obviously reduced as compared with 3.5 % Cy. The optimal concentration of chlorhexidinum was 0.5 %. This provides a new approach for infiltrative injection of the tumor for clinical use.

关键词： chlorhexidinum Lewis pulmonary carcinoma

Living-donor liver transplantation for patients with hepatocellular carcinoma in Japan: Current situations and challenge

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2020年第1期19卷 1-2页

作者： Yasuhiko Sugawara department of Transplantation/Pediatric surgery Postgraduate School of Life Science Kumamoto University

Liver transplantation has now been a standard therapy for patients with hepatocellular carcinoma(HCC)in the early stage[1].Liver transplantation is an ideal treatment for HCC which can treat both the tumors and the un... 详细信息

关键词： patients hepatocellular Liver

DNADam ageEffectsofHydroxyapatiteUltrofinePowderonW-256 Sarcom a Cells and Lym phocytes in Rats

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 1999年第3期19卷 215-218页

作者： XIA Qinghua 1, HU Panlin 2, CHEN Daoda 1, ZHANG Jianpin 1, TIAN Yuan 1, ZHANG Jinghui 1 1 department of General surgery, Xiehe Hospital, Tongji Medical University, Wuhan 430022 2 Departmnet of General surgery, Puqi Peoples Hospital, department of General surgery Xiehe Hospital Tongji Medical University Wuhan 430022

To explore the anticancer mechanism and DNA damages of hydroxyapatite ultrofine powder (HAUFP) on lymphocytes of rats, DNA damages in W 256 sarcoma cells and lymphocytes of rats were measured by single cell gel electrophoresis (SCGE). The results showed that HAUFP damaged DNA of W 256 sarcoma cells obviously but only cause slight damage of DNA of lymphocytes in rats. It is suggested that HAUFP selectively damaged DNA of tumor cells with only mild damage of lymphocyte DNA. HAUFP has powerful anticancer effect and little genetic toxicity.

关键词： hydroxyapatite ultrofine powder DNA damage anticancer effect rats

Flexner has fallen:Transitions in medical education system across time,a gradual return to pre-Flexnerian state(de-Flexnerization)

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第21期11卷 4966-4974页

作者： Nasser A N Alzerwi department of surgery Majmaah UniversityMajmaah 11952RiyadhSaudi Arabia

The modern medical education system has gradually evolved starting from 1910 incorporating the suggestions by Abraham Flexner,his public disclosure of the poor conditions at many medical schools provided a means to galvanize all the constituencies needed for reform to *** could say what other reformers could not,due to their links to the medical education *** now we are again going back to a pre-Flexnerian state due to multiple reasons such as gradually diminishing importance of basic science subjects for the students,the decline in the number and quality of investigator initiated research among clinical researchers,lesser emphasis to bedside training by means of detailed clinical examination and making appropriate observation of signs to reach to a diagnosis rather than over reliance on the laboratory tests and radiological modalities for the diagnosis,poor exposure to basic clinical skills starting from college throughout residency and the trend of disrespect and absenteeism from both theoretical and clinical/practical *** attitude of students is just to complete their required attendance so that they are not barred from appearing in *** de-Flexnerization trend and regression to pre-Flexnerian era standards,ideologies,structures,processes,and attitudes,are bound to beget pre-Flexnerian outcomes,for you get what you designed for.

关键词： Flexner era Medical education system Outcome based curriculum Basic sciences Early clinical exposure

Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2017年第1期19卷 98-102页

作者： Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng Ming-Kwong Yiu Division of Urology Department of Surgery The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong China Division of Urology Department of Surgery Queen Mary Hospital University of Hong Kong Hong Kong China.

We investigated the association of time to prostate-specific antigen nadir （TTPN） and logarithm of prostate-specific antigen velocity after progression Log（PSAVAP） in metastatic prostate cancer with prior primary androgen deprivation therapy （ADT）. All metastatic prostate cancer patients treated with primary ADT from 2000 to 2009 were reviewed. Patients who developed disease progression were included in the subsequent analyses. Patients were categorized into three groups according to their TTPN： TTPN of 〈3 months, 3-17 months, and 〉17 months. We compared the Log（PSAVAP） between the different TTPN groups using Mann-Whitney U-test and Kruskal-Wallis test. Further multiple linear regression analyses on Log（PSAVAP） were performed to adjust for other potential confounding factors. Among 419 patients who were treated with primary ADT, 306 patients developed disease progression with a median follow-up of 28 months, Longer TTPN was associated with lower Log（PSAVAP）（P = 0.008） within all subgroup analyses （TTPN of 〈3 vs 3-17 months, P = 0.020; TTPN of 3-17 vs 〉17 months, P = 0.009; and TTPN of 〈3 vs 〉17 months, P = 0.001）. Upon multiple linear regression analyses, baseline PSA （regression coefficient 0.001, P = 0.045）, PSA nadir （regression coefficient 0.002, P = 0.040）, and TTPN （regression coefficient -0.030, P = 0.001） were the three factors that were significantly associated with Log（PSAVAP）. In conclusion, a longer TTPN was associated with lower Log（PSAVAP） in metastatic prostate cancer patients following primary ADT. TTPN cut-offs at 3 months and 17 months appeared to have prognostic significance in predicting Log（PSAVAP）. TTPN may serve as a good prognostic indicator in deciding the treatment strategy in patients with disease progression.

关键词： androgen deprivation therapy prostate cancer prostate-specific antigen velocity after progression ti me to prostate-specific antigen nadir

Common bile duct injury by fibrin glue: Report of a rare complication

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第9期21卷 2854-2857页

作者： Yu-Long Yang Cheng Zhang Hong-Wei Zhang Ping Wu Yue-Feng Ma Mei-Ju Lin Li-Jun Shi Jing-Yi Li Mu Zhao department of Biliary Minimally Invasive surgery Affiliated Zhongshan Hospital of Dalian University

Fibrin glue is widely used in clinical practice and plays an important role in reducing postoperative *** report a case of a 65-year-old man, whose common bile duct was injured by fibrin glue, with a history of failed laparoscopic cholecystectomy and open operation for uncontrolled laparoscopic *** view of thepersistent liver dysfunction, xanthochromia and skin itching, the patient was admitted to us for further ***, computed tomography, and magnetic resonance cholangiopancreatography(MRCP) revealed multiple stones in the common bile duct, and liver function tests confirmed the presence of obstructive jaundice and liver *** retrograde cholangiopancreatography was unsuccessfully performed to remove choledocholithiasis, but a small amount of tissue was removed and pathologically confirmed as calcified biliary *** was followed by open surgery for suspicious *** was no evidence of cholangiocarcinoma, but the common bile duct wall had a defect of 8 mm × 10 mm at Calot's triangle.A hard, grid-like foreign body was removed, which proved to be solid fibrin ***, the residual choledocholithiasis was removed by a choledochoscopic procedure, and the common bile duct deletion was repaired by liver round ligament with T-tube *** months later, endoscopy was performed through the T-tube fistula and showed a well-repaired bile duct *** months later, MRCP confirmed no bile duct stenosis.A review of reported cases showed that fibrin glue is widely used in surgery, but it can also cause organ *** mechanism may be related to discharge reactions.

关键词： Fibrin glue Laparoscopic cholecystectomy Choledoch

A simple scoring system to estimate perioperative mortality following liver resection for primary liver malignancy-the Hepatectomy Risk Score(HeRS)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary surgery and Nutrition 2021年第3期10卷 315-324,I0001,I0002页

作者： Dimitrios Moris Brian I.Shaw Cecilia Ong Ashton Connor Mariya L.Samoylova Samuel J.Kesseli Nader Abraham Jared Gloria Robin Schmitz Zachary W.Fitch Bryan M.Clary Andrew S.Barbas department of surgery Duke University Medical CenterDurhamNCUSA

Background:Selection of the optimal treatment modality for primary liver cancers remains complex,balancing patient condition,liver function,and extent of *** individuals with preserved liver function,liver resection remains the primary approach for treatment with curative intent but may be associated with significant *** purpose of this study was to establish a simple scoring system based on Model for End-stage Liver Disease(MELD)and extent of resection to guide risk assessment for liver ***:The 2005-2015 NSQIP database was queried for patients undergoing liver resection for primary liver *** first developed a model that incorporated the extent of resection(1 point for major hepatectomy)and a MELD-Na score category of low(MELD-Na=6,1 point),medium(MELD-Na=7-10,2 points)or high(MELD-Na>10,3 points)with a score range of 1-4,called the Hepatic Resection Risk Score(HeRS).We tested the predictive value of this model on the dataset using logistic *** next developed an optimal multivariable model using backwards sequential selection of variables under logistic *** performed K-fold cross validation on both *** operating characteristics were plotted and the optimal sensitivity and specificity for each model were calculated to obtain positive and negative predictive ***:A total of 4,510 patients were *** was associated with increased odds of 30-day mortality[HeRS=2:OR=3.23(1.16-8.99),P=0.025;HeRS=3:OR=6.54(2.39-17.90),P<0.001;HeRS=4:OR=13.69(4.90-38.22),P<0.001].The AUC for this model was *** AUC for the optimal multivariable model was higher at *** K-fold cross validation,the positive predictive value(PPV)and negative predictive value(NPV)of these two models were similar at PPV=6.4%and NPV=97.7%for the HeRS only model and PPV=8.4%and NPV=98.1%for the optimal multivariable ***:The HeRS offers a simple heuristic for estimating 30-day mortality after resectio

关键词： Hepatocellular carcinoma(HCC) cholangiocarcinoma liver resection Model for End-stage Liver Disease(MELD) outcomes

Duplication of the Urethra in Boys: A Case Report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Urology 2024年第6期14卷 353-358页

作者： Mamadou Tidiani Coulibaly Falaye Sissoko Moumine Diarra Adama Toutou Diallo Issa Amadou Amadou Berthé Sory Koné CHU Gabriel Tour Urology Department Bamako University of Science Technology and Engineering Bamako Mali Lafiabougou Reference Health Center Bamako University of Science Technology and Engineering Bamako Mali CHU Gabriel Tour Pediatric Surgery Bamako University of Science Technology and Engineering Bamako Mali Korofina Reference Health Center Bamako University of Science Technology and Engineering Bamako Mali Segou Regional Hospital Bamako University of Science Technology and Engineering Bamako Mali

Supernumerary urethra in boys is a very rare anatomical entity. Sagittal urethral duplications are classified into four groups: epispadias, hypospadias, fusiform and Y-shaped urethra. The most widely used classification is that of Effmann and Lebowitz, which describes 6 types, one of the rarest being the ‘Y’ subtype IIA2, which corresponds to a duplicated urethral path from the vesical neck to an ectopic perineal or anal outlet. We report here the case of a 4-year-old child presenting with subtype IIA2 with a perineal orifice and no other urinary disorders.

关键词： Duplicity Ureter Malformation

Rehabilitation care for pain in elderly knee replacement patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第4期12卷 721-728页

作者： Li Liu Qiao-Zhen Guan Li-Fang Wang Wuhan Fourth Hospital Wuhan 430033Hubei ProvinceChina department of Orthopaedics Wuhan Third HospitalWuhan 430074Hubei ProvinceChina

BACKGROUND Total knee arthroplasty(TKA)is recognized as the most effective surgical intervention for relieving pain and improving joint mobility and deformity in patients with knee osteoarthritis and other synovial *** application of accelerated postoperative rehabilitation(enhanced recovery after surgery)has demonstrated its efficacy in improving patient outcomes,and early postoperative joint function exercise has become a key prognostic factor in knee *** unexpected appearance of limb pain and swelling hindered the patient’s tendency for early mobilization,leading in prolonged hospitalization,delayed functional recovery and negative psychological responses.A retrospective analysis was conducted on a cohort of 116 patients who under-went TKA at our hospital between July 2019 and July *** patients were divided into two groups:A control group(n=58)receiving programmatic nur-sing,and an observed group(n=58)receiving programmed nursing combined with a collaborative nursing model.A pain management team consisting of attending physicians,head nurses,and responsible nurses was *** measures included visual analogue scale(VAS)scores,activities of daily living(ADL)scale scores,and functional *** ADL scores of patients in both groups exhibited a continuous ***,there was no statistically significant difference in the ADL scores between the two groups at 48 h and the 7th d post-surgery(P>0.05).Upon reexamination at the 3rd mo,the observation group demonstrated higher ADL scores compared to the control group(67.48±14.69 vs 59.40±16.06,P0.05).The functional status of patients in both groups exhibited a gradual increase prior to intervention and at the 1st,2nd,and 3rd month following discharge(P<0.05).There was no statistically significant difference in knee joint function scores b

关键词： Programmed pain nursing Collaborative nursing Total knee arthroplasty