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Device-measured physical activity and sedentary time in the Nordic countries:A scoping review of population-based studies

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Journal of Sport and health Science 2024年第5期13卷 650-660页

作者： Ing-Mari Dohrn Jakob Tarp Jostein Steene-Johannessen Tommi Vasankari Maria Hagströmer Division of Physiotherapy Department of NeurobiologyCare Sciences and SocietyKarolinska Institutet14183 HuddingeSweden department of Sports medicine Norwegian School of Sports Sciences0806 OsloNorway UKK Institute for health promotion Research 33500 TampereFinland Faculty of medicine and health Technology Tampere University33100 TampereFinland Academic Primary health Care Centre Region Stockholm13365 StockholmSweden

Purpose:The purpose of this scoping review was to summarize and describe the methodology and results from population-based studies of physical activity and sedentary time measured with devices in the Nordic countries(Denmark,Finland,Iceland,Norway,and Sweden)and published in 2000 or ***:A systematic search was carried out in PubMed and Web of Science in June 2023 using predefined search ***:Fourteen unique research projects or surveillance studies were ***,2 surveillance studies published by national agencies were included,resulting in a total of 16 studies for *** surveillance systems exist in Finland and Norway,with regular survey waves in school-aged children/adolescents and *** Denmark,recent nationally representative data have been collected in school children *** far,Sweden has no regular national surveillance system using device-based data *** studies were found from *** first study was conducted in 2001 and the most recent in 2022,with most data collected from 2016 to *** studies included children/adole scents 6-18 years,no study included *** total 11 studies included adults,of which 8 also covered older *** study focused specifically on older *** analytical sample size ranged from 205 to 27,*** methodology is presented,such as information on sampling strategy,device type and placement,wear protocols,and physical activity classification *** of physical activity and sedentary time in children/adolescents,adults,and older adults across the Nordic countries are ***:A growing implementation of device-based population surveillance of physical activity and sedentary behavior in the Nordic countries has been *** variety of devices,placement,and data procedures both within and between the Nordic countries highlights the challenges when it comes to comparing study outcomes as well as the need for more standa

关键词： Accelerometer Light intensity Moderate-vigorous intensity Surveillance Wearable devices

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Psychosocial Stress Modifies the Acute Cardiac health Effects of Traffic-Related Air Pollution

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Environment & health 2024年第1期2卷 11-22页

作者： Tongjun Guo Wanzhou Wang Xi Chen Huaqi Guo Kai Wang Yating Ma Hongyan Deng Xianggui Li Anqi Shan Qian Wu Yaoyan Li Hongyu Li Qisijing Liu Juan Chen Yang Lan Jian Lei Furong Deng Zhiwei Sun Xinbiao Guo Shaowei Wu Yan Wang Naijun Tang department of Occupational and Environmental health Sciences School of Public HealthPeking UniversityBeijing 100191China department of Occupational and Environmental health Tianjin Key Laboratory of EnvironmentNutrition and Public HealthSchool of Public HealthTianjin Medical UniversityTianjin 300070China department of Respiratory and Critical Care medicine The Ninth People’s Hospital of Shanghai Jiao Tong University School of MedicineShanghai 200025China department of Occupational and Environmental health School of Public HealthXi’an Jiaotong University Health Science CenterXi’anShaanxi 710049China Key Laboratory of Trace Elements and Endemic Diseases in Ministry of health Xi’anShaanxi 710049China Key Laboratory for Disease Prevention and Control and health promotion of Shaanxi Province Xi’anShaanxi 710049China Institute of social Psychology School of Humanities and Social SciencesXi’an Jiaotong UniversityXi’anShaanxi 710049China Qinglongqiao Community health Service Centre Beijing 100091China Key Laboratory of Environment and Genes Related to Diseases(Xi’an Jiaotong University) Ministry of EducationXi’an 710061China School of Public health Shanghai Jiao Tong University School of MedicineShanghai 200025China department of HAI Management Tianjin Huanhu HospitalTianjin 300060China Office for National Clinical Research Center for Geriatric Diseases Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100005China Research Institute of Public health School of MedicineNankai University300071 TianjinChina department of Toxicology and Sanitary Chemistry School of Public HealthCapital Medical UniversityBeijing 100069China Beijing Key Laboratory of Environmental Toxicology Capital Medical UniversityBeijing 100069China The Ninth People’s Hospital of Shanghai Jiao Tong University School of medicine Shanghai 200011China

Previous studies have shown that exposure to black carbon(BC,a tracer of traffic-related air pollution)and psychosocial stress are both associated with adverse cardiac effects,but whether psychosocial stress could modify the cardiac effects of BC is *** investigate the potential modifying effect of psychosocial stress on the associations between acute exposure to BC and typical cardiac health variables,real-time personal 24 h measurements were conducted in a repeated-measure study among adults with elevated blood pressure(high-risk group)and a panel study among normal adults(low-risk group)in *** cardiac health variables included ST-segment depression events,heart rate,and heart rate variability(HRV)*** Stress Scale,State Anxiety Inventory and Self-rating Depression Scale were used to assess the recent psychosocial stress status of the participants,and a composite stress index was established based on these *** linear mixed-effects model was used to analyze the associations between BC exposure and cardiac health variables and potential effect modification by psychosocial stress.A total of 9724 h measurements among 97 participants in the repeated-measure study and 20224 h measurements among 87 participants in the panel study were included in the final *** BC exposure was significantly associated with increased ST-segment depression events and heart rate and decreases in HRV in both *** marginal effects of acute BC exposure on most cardiac health variables generally tended to be amplified under higher vs low levels of psychosocial stress in both studies,with the composite stress index apparently modifying the associations of BC exposure with most ST-segment depression events and HRV *** findings suggest that psychosocial stress may increase the participants’cardiac susceptibility to BC exposure,which could be helpful for the identification of susceptible individuals in the context of traff

关键词： Air pollution Black carbon Cardiac health Effect modification Psychosocial stress

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Chrononutrition in traditional European medicine-Ideal meal timing for cardiometabolic health promotion

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Journal of Integrative medicine 2024年第2期22卷 115-125页

作者： Nora Selena Eberli Ludivine Colas Anne Gimalac department of Traditional European medicine Navi Institute of Research in Integrative HealthEcole Professionnelle Superieure de NaturopathieCentre Andre Henzelin1066 EpalingesSwitzerland

Meal timing plays a crucial role for cardiometabolic health,given the circadian regulation of cardiometabolic ***,to the best of our knowledge,no concept of meal timing exists in traditional European medicine(TEM).Therefore,in this narrative review,we aim to define the optimal time slot for energy intake and optimal energy distribution throughout the day in a context of TEM and explore further *** reviewing literature published between 2002 and 2022,we found that optimal timing for energy intake may be between 06:00 and 09:00,12:00 and 14:00,and between 15:00 and18:00,with high energy breakfast,medium energy lunch and low energy dinner and possibly further adjustments according to one’s chronotype and ***,timing and distribution of energy intake may serve as a novel therapeutic strategy to optimize coction,a concept describing digestion and metabolism in TEM.

关键词： Circadian rhythm Chrononutrition Naturopathy Traditional European medicine Metabolic syndrome Meal timing

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A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults—China,2017–2021

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China CDC weekly 2024年第23期6卷 537-541,I0001-I0007页

作者： Yidan Qiu Saisai Ji Chen Chen Jinhui Zhou Jun Wang Bing Wu Yuan Wei Fangyu Li Xulin Zheng Lanjing Xu Zheng Zhang Feng Zhao Guangdi Chen John SJi Yuebin Lyu Shilu Tong Xiaoming Shi department of Big Data in health Science School of Public HealthZhejiang UniversityHangzhou CityZhejiang ProvinceChina China CDC Key Laboratory of Environment and Population health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina Center for Global health School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina department of Epidemiology and Biostatistics School of Public HealthJilin UniversityChangchun CityJilin ProvinceChina School of Public health China Medical UniversityShenyang CityLiaoning ProvinceChina Institute of Environmental health School of Public Healthand Bioelectromagnetics LaboratorySchool of MedicineZhejiang UniversityHangzhou CityZhejiang ProvinceChina Environmental Research Center Duke Kunshan UniversityKunshan CityJiangsu ProvinceChina Nicholas School of the Environment Duke UniversityDurhamNCUSA School of Public health Institute of Environment and Population HealthAnhui Medical UniversityHefei CityAnhui ProvinceChina School of Public health and social Work Queensland University of TechnologyBrisbaneAustralia

What is already known about this topic?Antimony(Sb)has been identified as a new neurotoxicant that impacts neurological functions in animal ***,its effects on the human population remain *** is added by this report?The study reveals that there is an association between exposure to Sb and a higher incidence of cognitive impairment in older *** dose-response curve demonstrates that the risk of cognitive impairment consistently increased with higher levels of Sb exposure without a discernible *** are the implications for public health practice?Reducing exposure to Sb may have a beneficial effect in delaying or preventing the onset of cognitive *** intervention has the potential to significantly decrease the disease burden associated with cognitive impairment,ultimately contributing to social development.

关键词： Antimony development. exposure

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Differential Impact of Fertility on health-Adjusted Life Expectancy of Older Adults Across Countries of Various Levels of Socio-Demographic Index—Worldwide,1995-2019

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China CDC weekly 2024年第39期6卷 991-995页

作者： Shuai Guo Chen Chen Yunhe Wang Yi Cao Zhiwei Leng Xiaoying Zheng department of Population health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina School of Population medicine and Public health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina Nuffield department of Population health University of OxfordOxfordUK Center for health Policy and health Economics National Infrastructures for Translational MedicineInstitute of Clinical MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina Institute for Global health and Development Peking UniversityBeijingChina

What is already known about this topic?health-adjusted life expectancy(HALE)is a crucial indicator of global health,which is strongly correlated with the socio-demographic index(SDI)and population *** is added by this report?This study revealed that the correlation between total fertility rate(TFR)and HALE of older adults varies across countries with different SDI levels,offering valuable insights for the development of more targeted health promotion programs and *** are the implications for public health practice?Different health interventions should be tailored to countries with different levels of *** countries with both low fertility rates and low SDI,advanced measures are needed to address the challenge of an aging population that may live longer but face poorer health in the future.

关键词： demographic fertility offering

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The gut–liver axis calibrates PEDF production for ISC homeostasis

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Biophysics Reports 2024年第3期10卷 175-177页

作者： Ying Huang Xinran Wang Lulu Sun State Key Laboratory of Female Fertility promotion Department of Endocrinology and Metabolism Peking University Third Hospital Institute of Advanced Clinical medicine Peking University

The biliary tract, portal vein, and systemic circulation are the anatomical linkages that enable bidirectional inter-organ communications through the gut–liver axis.(Han et al. 2023). Under physiological conditions, the proliferation of intestinal stem cells(ISCs) materializes the self-renewal of the intestinal epithelium for gut barrier integrity(van der Flier and Clevers 2009), and such crosstalk contributes to the repair capacity of the intestinal tract by accommodating the ISCs(Chen et al.2022; Hegyi et al. 2018). Nonetheless, in pathological conditions such as inflammatory bowel disease(IBD),the compromised intestinal barrier caused by inflammation increases the translocation of microorganisms(Wigg et al. 2001).

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Epidural pressure measurement using a fiber-optic sensor(proof-of-principle in vivo animal trial)

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Animal Models and Experimental medicine 2024年第5期 769-776页

作者： Susanne Barz Marvin Friedemann Sebastian Voigt Markus Melloh Thomas Barz department of Anaesthesiology Intensive Care Medicine and Pain TherapyRostock University Medical CenterUniversit?tsmedizin Rostock Chemnitz University of Technology School of Public health and social Work Queensland University of Technology Orthopedic department University of Greifswald

Background: An increase in epidural pressure around the stenosis has been observed in patients with lumbar spinal stenosis(LSS) with positive signs of sedimentation or redundant nerve roots. Further analysis of the pressure conditions in the stenotic area would be of great interest. We hypothesized that it would be possible to determine the physiological parameters of the epidural pulse wave and its course in pathological stenosis as a basis for objective identification of LSS based on pressure using a new measuring method with continuous spatial and temporal resolution. Methods: We performed a single-case proof-of-principle in vivo animal trial and used a newly developed hybrid pressure-measurement probe with a fiber-tip Fabry–Pérot interferometer and several fiber Bragg gratings(FBG). Results: With reproducible precision, we determined the mean epidural pressure to be 7.5 mmHg and the peak-to-peak value to be 4–5 mmHg. When analyzing the pressure measured by an FBG array, both the heart and respiratory rates can be precisely determined. This study was the first to measure the pulse wave velocity of the cerebrospinal fluid pressure wave as 0.97 m/s using the newly developed pressure probe. A simulated LSS was detected in real time and located exactly. Conclusions: The developed fiber-optic pressure sensor probe enables a new objective measurement of epidural pressure. We confirmed our hypothesis that physiological parameters of the epidural pulse wave can be determined and that it is possible to identify an LSS.

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Children with obesity have poorer circadian health as assessed by a global circadian health score

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World Journal of Pediatrics 2024年第8期20卷 787-800页

作者： María Rodríguez-Martín Nuria Martínez-Lozano Vicente Santaclara-Maneiro Antonio Gris-Peñas Diego Salmerón Rafael Ríos Asta Tvarijonaviciute Marta Garaulet department of Physiology Regional Campus of International Excellence University of Murcia Murcia Spain Biomedical Research Institute of Murcia IMIB-Arrixaca-UMU University Clinical Hospital Murcia Spain health Area of Lorca Lorca Spain health and social Sciences department University of Murcia Murcia Spain Consortium for Biomedical Research in Epidemiology and Public health Madrid Spain Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU) University of Murcia Murcia Spain Division of Sleep and Circadian Disorders Brigham and Women’s Hospital (BWH) and Division of Sleep Medicine Harvard Medical School Boston USA

Background Circadian health refers to individuals’well-being and balance in terms of their circadian *** is influenced by external *** adults,a close relationship between circadian-related alterations and obesity has been ***,studies in children are scarce,and circadian health and its association with obesity have not been evaluated *** aimed to assess whether circadian health differed between children with and without obesity as determined by a global circadian score(GCS)in a school-age *** Four hundred and thirty-two children(7–12 years)were recruited in ***-invasive tools were used to calculate the GCS:(1)7-day rhythm of wrist temperature(T),activity(A),position(P),an integrative variable that combines T,A,and P(TAP);(2)cortisol;and(3)7-day food and sleep *** mass index,body fat percentage,waist circumference(WC),melatonin concentration,and cardiometabolic marker levels were *** Circadian health,as assessed by the GCS,differed among children with obesity,overweight,and normal weight,with poorer circadian health among children with *** with obesity and abdominal obesity had 3.54 and 2.39 greater odds of having poor circadian health,respectively,than did those with normal weight or low *** percentage of rhythmicity,a marker of the robustness of the TAP rhythm,and the amplitude,both components of the GCS,decreased with increasing *** lifestyle behaviors were involved in the association between circadian health and obesity,particularly protein intake(P=0.024),physical activity level(P=0.076)and chronotype(P=0.029).Conclusions The GCS can capture the relationship between circadian health and obesity in school-age *** intake,physical activity level,and chronotype were involved in this *** intervention based on improving circadian health may help to prevent childhood obesity.

关键词： Children Chronodisruption Circadian Lifestyle Obesity

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Global public concern of childhood and adolescence suicide:a new perspective and new strategies for suicide prevention in the post-pandemic era

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World Journal of Pediatrics 2024年第9期20卷 872-900页

作者： Soeun Kim Jaeyu Park Hyeri Lee Hayeon Lee Selin Woo Rosie Kwon Sunyoung Kim Ai Koyanagi Lee Smith Masoud Rahmati Guillaume Fond Laurent Boyer Jiseung Kang Jun Hyuk Lee Jiyeon Oh Dong Keon Yon Center for Digital health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea department of Precision medicine Kyung Hee University College of MedicineSeoulSouth Korea department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea department of Family medicine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Centre for health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran department of Physical Education and Sport Sciences Faculty of Literature and HumanitiesVali-e-Asr University of RafsanjanRafsanjanIran CEReSS-health Service Research and Quality of Life Center Assistance Publique-Hôpitaux de MarseilleAix Marseille UniversityMarseilleFrance department of Anesthesia Critical Care and Pain MedicineMassachusetts General HospitalBostonMAUSA Division of Sleep medicine Harvard Medical SchoolBostonMAUSA health and Human Science University of Southern CaliforniaLos AngelesCAUSA department of medicine Kyung Hee University College of MedicineSeoulSouth Korea department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-roDongdaemun-guSeoul02447South Korea

Background Suicide is the second leading cause of death in young people worldwide and is responsible for about 52,000 deaths annually in children and adolescents aged 5-19 ***,social,psychological,and behavioral factors play important roles in suicide *** traumatic events such as the COVID-19 pandemic may contribute to suicidal behaviors in young people,there is a need to understand the current status of suicide in adolescents,including its epidemiology,associated factors,the influence of the pandemic,and management *** sources We investigated global and regional suicide mortality rates among children and adolescents aged 5-19 years using data from the Global Burden of Diseases,Injuries,and Risk Factors Study(GBD)*** suicide mortality rates from 1990 to 2019 were examined in 204 countries and territories across six World health Organization(WHO)***,we utilized electronic databases,including PubMed/MEDLINE and Scopus,and employed various combinations of terms such as“suicide”,“adolescents”,“youth”,“children”,“risk factors”,“COVID-19 pandemic”,“prevention”,and“intervention”to provide a narrative review on suicide within the pediatric population in the post-pandemic *** Despite the decreasing trend in the global suicide mortality rate from 1990 to 2019,it remains *** mortality rates from suicide by firearms or any other specified means were both greater in ***,Southeast Asia had the highest suicide rate among the six WHO *** COVID-19 pandemic seems to contribute to suicide risk in young people;thus,there is still a strong need to revisit appropriate management for suicidal children and adolescents during the *** The current narrative review integrates up-to-date knowledge on suicide epidemiology and the effects of the COVID-19 pandemic,risk factors,and intervention *** numerous studies have characterized trends in suicide among young people during the

关键词： COVID-19 Global Pandemic Suicide Children Adolescents

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Association of Mosaic Chromosomal Alterations and Genetic Factors with the Risk of Cirrhosis

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Journal of Clinical and Translational Hepatology 2024年第6期12卷 562-570页

作者： Xinyuan Ge Lu Zhang Maojie Liu Xiao Wang Xin Xu Yuqian Yan Chan Tian Juan Yang Yang Ding Chengxiao Yu Jing Lu Longfeng Jiang Qiang Wang Qun Zhang Ci Song department of Epidemiology China International Cooperation Center on Environment and Human HealthCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsuChina The Dumont-UCLA Transplant Center Division of Liver and Pancreas TransplantationDepartment of SurgeryDavid Geffen School of Medicine at UCLALos AngelesCAUSA department of health promotion Center Jiangsu Province Hospital and Nanjing Medical University First Affiliated HospitalNanjingJiangsuChina department of Infectious Disease The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina department of Clinical Science Intervention and Technology(CLINTEC)Karolinska InstitutetStockholmSweden Changzhou Medical Center Nanjing Medical UniversityNanjingJiangsuChina Research Units of Cohort Study on Cardiovascular Diseases and Cancers Chinese Academy of Medical SciencesBeijingChina Collaborative Innovation Center for Cancer Personalized medicine Nanjing Medical UniversityNanjingJiangsuChina

Background and Aims:Age-related mosaic chromosomal alterations(mCAs)detected from genotyping of blood-de-rived DNA are structural somatic variants that indicate clonal *** study aimed to investigate whether mCAs contribute to the risk of cirrhosis and modify the effect of a polygenic risk score(PRS)on cirrhosis risk ***:mCA call sets of individuals with European ancestry were obtained from the UK *** PRS was constructed based on 12 susceptible single-nucleotide poly-morphisms for *** proportional hazard models were applied to evaluate the associations between mCAs and cirrhosis ***:Among 448,645 individuals with a median follow-up of 12.5 years,we identified 2,681 cas-es of cirrhosis,1,775 cases of compensated cirrhosis,and 1,706 cases of decompensated *** to non-carriers,individuals with copy-neutral loss of heterozygosity mCAs had a significantly increased risk of cirrhosis(hazard ratio(HR)1.42,95%confidence interval(CI)1.12-1.81).This risk was higher in patients with expanded cell fractions of mCAs(cell fractions≥10%*** fractions<10%),especially for the risk of decompensated cirrhosis(HR 2.03[95%CI 1.09-3.78]vs.1.14[0.80-1.64]).In comparison to non-carriers of mCAs with low genetic risk,individuals with expanded copy-neutral loss of heterozygosity and high genetic risk showed the highest cirrhosis risk(HR5.39[95%CI 2.41-12.07]).Conclusions:The presence of mCAs is associated with increased susceptibility to cirrhosis risk and could be combined with PRS for personalized cirrhosis risk stratification.

关键词： UK Biobank Cirrhosis Mosaic chromosomal alterations Polygenic risk score Genetic susceptibility Interaction effect

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