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Relationship between Inter Canine Width and Inter Alar Width, Inter Commissural Width, and Inter Canthal Distance: A Pilot Study

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Open Journal of Stomatology 2024年第6期14卷 279-290页

作者： Grevisse Bindele Ndombolo Augustin Mantshumba Milolo Fidele Nyimi Bushabu Em Kalala Kazadi Pierrot Kumpanya Ntumba Jean Marie Kayembe Bukama Elias Lubadi Tshilumba Jean Paul Sekele Isouradi department of prosthodontics Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo National Center of Research in Dental Sciences Kinshasa Democratic Republic of the Congo department of Oral and Maxillofacial Surgery Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo department of Periodontology Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo department of Operative Dentistry Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo

The aim of this study was to determine the relationship between inter canine width (ICW) and inter alar width (IAW), inter commissural width (ICoW), and inter canthal distance (ICaD) in Bantu population. Materials and Methods: It was a pilot study included all participants who were aged at least 18 years, without a history of orthodontics treatment from prosthodontics department, Faculty of Dental Medicine, University of Kinshasa. The Ethics committee of the National Center of Research for Dental Sciences in DR Congo approved the study protocol (CNRSB 1504.218). The participants medical records were obtained from the interview and dental examination. Nature of the study was explained with participant information sheet, and an informed consent of all participants was obtained. The inclusion criteria were no missing maxillary and mandibular teeth, no diastema, and no anterior restorations, 18 years old before enrollment in the study. The exclusion criteria were inability to meet the above requirements, pregnancy, and refusal to participate in the study. The inter-canine width (ICW), inter alar width (IAW), inter canthal distance (ICaD) and inter-commissural width (ICoW) of each participant were measured with a digital Vernier caliper (Mitutoyo, UK Ltd.,) (0.01 mm) three times and the average value was recorded. The inter canthal distance (ICaD) was measured without applying pressure by bringing the recording parts of the caliper just in contact with the medial angle. The inter alar width (IAW) was marked with a fine marked pencil on the widest outer surface of the alae of the nose on either side or width. Those two points were measured without applying pressure by bringing the recording parts of the caliper just in contact with the outer surface. The participant was told to stop breathing shortly to avoid any change in shape of the nose. The inter-commissural width (ICoW) was determined by measuring the maxillary lip vermilion from commissure to commissure without the

关键词： Relationship Inter-Canine Width Inter Alar Width Inter Canthal Distance Inter Commissural Width

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Update on the use of 45S5 bioactive glass in the treatment of bone defects in regenerative medicine

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World Journal of Orthopedics 2024年第3期15卷 204-214页

作者： Dayane Maria Braz Nogueira Marcelie Priscila de Oliveira Rosso Daniela Vieira Buchaim Mariana Schutzer Ragghianti Zangrando Rogério Leone Buchaim department of prosthodontics and Periodontics Bauru School of DentistryUniversity of São PauloBauru 17012-901Brazil department of Biological Sciences Bauru School of DentistryUniversity of São PauloBauru 17012-901Brazil Medical School University Center of AdamantinaAdamantina 17800-000Brazil Postgraduate Program in Structural and Functional Interactions in Rehabilitation Postgraduate DepartmentUniversity of MaríliaMarília 17525-902Brazil

Bone regeneration is a critical area in regenerative medicine,particularly in orthopedics,demanding effective biomedical materials for treating bone defects.45S5 bioactive glass(45S5 BG)is a promising material because of its osteoconductive and bioactive *** research in this field continues to advance,keeping up-to-date on the latest and most successful applications of this material is *** achieve this,we conducted a comprehensive search on Pub-Med/MEDLINE,focusing on English articles published in the last *** search used the keywords“bioglass 45S5 AND bone defect”in *** found 27 articles,and after applying the inclusion criteria,we selected 15 studies for detailed *** of these studies compared 45S5 BG with other cement or scaffold *** comparisons demonstrate that the addition of various composites enhances cellular biocompatibility,as evidenced by the cells and their osteogenic ***,the use of 45S5 BG is enhanced by its antimicrobial properties,opening avenues for additional investigations and applications of this biomaterial.

关键词： Biocompatible materials Bioglass Bone regeneration

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Self-adaptive hydrogel for breast cancer therapy via accurate tumor elimination and on-demand adipose tissue regeneration

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Chinese Chemical Letters 2024年第1期35卷 371-378页

作者： Ran Tian Xinyu Qiu Wenyun Mu Bolei Cai Zhongning Liu Shiyu Liu Xin Chen School of Chemical Engineering and Technology Department of Chemical EngineeringShaanxi Key Laboratory of Energy Chemical Process IntensificationXi'an Jiao Tong UniversityXi'an 710049China School of Stomatology State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi Clinical Research Center for Oral DiseasesDepartment of Preventive DentistryThe Fourth Military Medical UniversityXi'an 710032China School of Stomatology State Key Laboratory of Military StomatologyDepartment of Oral and Maxillofacial SurgeryThe Fourth Military Medical UniversityXi'an 710032China department of prosthodontics Peking University School and Hospital of StomatologyNational Clinical Research Center for Oral DiseasesNational Engineering Laboratory for Digital and Material Technology of StomatologyBeijing Key Laboratory of Digital StomatologyBeijing 100081China School of Stomatology State Key Laboratory of Military StomatologyNational Clinical Research Center for Oral DiseasesShaanxi International Joint Research Center for Oral DiseasesCenter for Tissue EngineeringThe Fourth Military Medical UniversityXi'an 710032China

The irregular defects and residual tumor tissue after surgery are challenges for effective breast cancer ***,a smart hydrogel with self-adaptable size and dual responsive cargos release was fabricated to treat breast cancer via accurate tumor elimination,on-demand adipose tissue regeneration and effective infection *** hydrogel consisted of thiol groups ended polyethylene glycol(SH-PEG-SH)and doxorubicin encapsulated mesoporous silica nanocarriers(DOX@MSNs)double crosslinked hyaluronic acid(HA)after loading of antibacterial peptides(AP)and adipose-derived stem cells(ADSCs).A pH-cleavable unsaturated amide bond was pre-introduced between MSNs and HA frame to perform the tumor-specific acidic environment dependent DOX@MSNs release,meanwhile an esterase degradable glyceryl dimethacrylate cap was grafted on MSNs,which contributed to the selective chemotherapy in tumor cells with over-expressed *** bond cleavage between MSNs and HA would also cause the swelling of the hydrogel,which not only provide sufficient space for the growth of ADSCs,but allows the hydrogel to fully fill the irregular defects generated by surgery and residual tumor atrophy,resulting in the on-demand regeneration of adipose ***,the sustained release of AP could be simultaneously triggered along with the size change of hydrogel,which further avoided bacterial infection to promote tissue regeneration.

关键词： Smart hydrogel with self-adaptable size Breast cancer therapy Dual responsive cargoes release Selective tumor elimination On-demand adipose tissue regeneration Effective bacteria inhibition

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Classification and detection of dental images using meta-learning

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World Journal of Clinical Cases 2024年第32期12卷 6559-6562页

作者： Pradeep Kumar Yadalam Raghavendra Vamsi Anegundi Mario Alberto Alarcón-Sánchez Artak Heboyan department of Periodontics Saveetha Dental College and HospitalSaveetha Institute of Medical and Technical SciencesSaveetha UniversityChennai 600077Tamil NaduIndia South Pacific Dental Institute Chilpancingo de los Bravo 39022GuerreroMexico department of prosthodontics Faculty of StomatologyYerevan State Medical University after Mkhitar HeratsiYerevan 0025Armenia

Meta-learning of dental X-rays is a machine learning technique that can be used to train models to perform new tasks quickly and with minimal *** of just memorizing a task,this is accomplished through teaching a model how to *** for meta-learning are typically trained on a collection of training problems,each of which has a limited number of labelled *** Xray classification tasks,including the detection of pneumonia,coronavirus disease 2019,and other disorders,have demonstrated the effectiveness of ***-learning has the benefit of allowing models to be trained on dental X-ray datasets that are too few for more conventional machine learning *** to the high cost and lengthy collection process associated with dental imaging datasets,this is significant for dental X-ray classification *** ability to train models that are more resistant to fresh input is another benefit of meta-learning.

关键词： Artificial intelligence Meta-learning Dental diagnosis Image segmentation Medical image interpretation Dental radiography

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Effect of Different Pretreatments to Post-space on Bonding Strength of Fiber Posts Luted with a Self-adhesive Resin Cement

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Journal of Wuhan University of Technology(Materials Science) 2013年第5期28卷 984-989页

作者：夏勇程祥荣 department of prosthodontics School and Hospital of StomatologyWuhan University

The effects of different post-space pretreatments on the retentive force of fiber posts cemented with a self-adhesive resin cement were investigated. Twenty-eight single-canal premolars were obturated by Resilon using warm vertical compaction and treated with distilled water, 2.5% NaOCl, 17% EDTA and 2.5% NaOCI; or 17% EDTA, 2.5% NaOCI, and ultrasonic agitation （U/E/N treatment）. Subsequently, radicular dentin surfaces were observed under scanning electron microscopy （SEM）. RelyX Fiber Posts were cemented in the treated canals by using RelyX U100, and thin-slice push-out test and SEM observation of coronal and apical regions of the specimens were performed. Data were analyzed using two-way ANOVA and Tukey＇s HSD post- hoc tests, and the percentage of failure type was calculated. Ultrasonic/EDTA/NaOC1 irrigation showed the maximum effectiveness in removing the smear layer and debris on the dentin surface. The apical bond strength of the experimental groups was significantly higher than that of the control group （P〈 0.05）. Adhesive failure between cement and dentin was the most common mode of failure. No obvious RDIZ or resin tag was detected. Chemical irrigants facilitated the bonding of these fiber posts, and ultrasonic activation improved retention. Future studies should evaluate the effectiveness of irrigation on fiber post push-out strength in fatigue cycling condition.

关键词： irrigation post space push-out strength Resilon self-adhesive cements smear layer

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Study on repairing canine mandibular defect with porous Mg-Sr alloy combined with Mg-Sr alloy membrane

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Regenerative Biomaterials 2020年第3期7卷 331-336页

作者： Shanning Zhang Xirao Sun Chunyu Kang Man Yang Yuan Zhao Chengyue Wang department of prosthodontics Second Affiliated Hospital of Jinzhou Medical UniversityJinzhou 121000China department of prosthodontics JinZhouShi Oral Cavity HospitalJinzhou 121000China

To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in *** second and third mandibular premolars on both sides were extracted from six *** model of mandible buccal fenestration bone defects were prepared after the sockets *** bone defects were randomly divided into groups A and B,then Mg-Sr alloy was implanted in bone defects of group A and covered by Mg-Sr alloy membrane while Mg-Sr alloy was implanted in bone defects of group B and covered by mineralized collagen *** defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4,8 and 12 *** 12 weeks,the healing of bone defects were evaluated by gross observation,X-ray microscopes and histological observation of hard *** defects in each group were *** 8 and 12 weeks,the gray value of group A was higher than that of group B(P<0.05).At 12 weeks,the bone volume fraction of group A was higher than that of group B(P<0.05).The newly woven bone in group A is thick and arranged staggered,which was better than that of group *** Mg-Sr alloy combined with Mg-Sr alloy membrane could further promote the repair of mandibular defects,and obtain good osteogenic effect.

关键词： Mg-Sr alloy Mg-Sr alloy membrane mineralized collagen membrane mandibular defects guided bone regeneration

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New Mini Dental Implant Attachments versus O-ring Attachment after Cyclic Aging: Analysis of Retention Strength and Gap Space

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2017年第3期37卷 419-424页

作者： Abdalbseet A Fatalla 宋珂曹颖光 department of prosthodontics and Implantology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology department of prosthodontics College of Dentistry University of Baghdad

Overdenture as a treatment modality for both partially and fully edentulous patients is costeffective and less expensive. The purpose of the present study was to examine the newly fabricated attachments by comparing them with conventional O-ring attachment in vitro in terms of retention force and cyclic aging resistance. A total of 150 samples were prepared and divided into five groups according to the materials used(O-ring attachment, Deflex M10 XR, Deflex Classic SR, Deflex Acrilato FD, and flexible acrylic resin). The retention force of different attachments was measured by a mini dental implant after three subsequent aging(0, 63, and 126) cycles in the circumstances similar to the oral environment. The gap space between the head of the implant and the inner surface of the attachments was detected. Two-way analysis of variance(ANOVA) analysis with multiple comparisons test was applied for statistical analysis. The results showed that Deflex M10 XR had the highest retention force and the lowest gap space after cyclic aging; in addition, by comparing the relative force reduction, the lowest values were obtained in the O-ring attachment and the highest values in the flexible acrylic resin attachment. The retention force measured after cyclic aging for the Deflex M10 XR attachment was greatly improved when compared with the O-ring attachment and other types of attachment materials; in addition, the Deflex M10 XR attachment exhibited the minimum gap space between the inner surface and the mini dental implant head. In conclusion, Deflex M10 XR has the ability to withstand weathering conditions and retains its durable and retentive properties after aging when compared with other attachments.

关键词： mini dental implant O-ring attachment flexible acrylic resin deflex material

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Clinical Data-Driven Finite Element Analysis of the Kinetics of Chewing Cycles in Order to Optimize Occlusal Reconstructions Dedicated to Professor Karl Stark Pister for his 95th birthday

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Computer Modeling in Engineering & Sciences 2021年第12期129卷 1259-1281页

作者： Simon Martinez Jurgen Lenz Hans Schindler Willi Wendler Stefan Rues Karl Schweizerhof Sophia Terebesi Nikolaos Nikitas Giannakopoulos Marc Schmitter Institute of Mechanics Karlsruhe Institute of Technology(KIT)KarlsruheGermany department of prosthodontics Dental SchoolUniversity of WurzburgWurzburgGermany department of prosthodontics University of HeidelbergHeidelbergGermany

The occlusal design plays a decisive role in the fabrication of dental *** and dental technicians depend on mechanical simulations of mandibular movement that are as accurate as possible,in particular,to produce interference-free yet chewing-efficient dental *** this,kinetic data must be available,i.e.,movements and deformations under the influence of forces and *** the present study,so-called functional data were collected from healthy volunteers to provide consistent information for proper *** the latter purpose,biting and chewing forces,electrical muscle activity and jaw movements were registered synchronously,and individual magnetic resonance tomograms(MRI)were *** acquired data were then added to a large complex finite element model of the complete masticatory system using the functional information obtained and individual anatomical geometries so that the kinetics of the chewing process and teeth grinding could be realistically *** allows developing algorithms that optimize computer-aided manufacturing of dental prostheses close to *** this way,a failure-free function of the dental prosthesis can be guaranteed and its damage during usage can be reduced or prevented even including endosseous implants.

关键词： Occlusal design mechanical simulations of mandibular movement finite element model of the complete masticatory system simulation of chewing process and teeth grinding

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Porous titanium granules in critical size defects of rabbit tibia with or without membranes

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International Journal of Oral Science 2014年第2期6卷 105-110页

作者： Rafael Arcesio Delgado-Ruiz Jose Luis Calvo-Guirado Marcus Abboud Maria Piedad Ramirez-Ferna'ndez Jose Eduardo Maté-Snchez Bruno Negri Alex Won Georgios Romanos department of prosthodontics and Digital Technology School of Dental Medicine Stony Brook University Stony Brook USA department of prosthodontics and Digital Technology School of Medicine and Dentistry Murcia University Murcia Spain

Recently, porous titanium granules （PTGs） have been indicated for the preservation of the dimensions of post-extraction sockets, as a filler in sinus lift procedures and for the treatment of peri-implant and periodontal defects, based on the osteoconductivity and dimensional stability of the titanium granules. However, there is a lack of information regarding the use of this material in larger defects and in conjunction with membranes. The objective of this study is to test the behavior of PTGs used to fill critical size defects in rabbit tibiae, with and without membranes. Critical defects were created in both tibiae of rabbits, divided randomly into three groups： Group A （defect filled with PTG）, Group B （defect filled with PTG＋collagen membrane） and a control group （empty defect）. After six weeks, histomorphometric analysis was performed. The results showed more defect closures at the cortical area （87.37%±2.2%） and more bone formation at the marrow area （57.6%± 1.3%） in Group B, in comparison with the other groups （P〈0.05）; the use of membranes improved the material stability expressed as more percentages of the original material when membranes were used （P〈0.05）. Finally, inflammatory reactions were observed when the granules were not protected by membranes. In spite of the limitations of this animal study, it may be concluded that PTG particles are osteoconductive and allow bone growth. The PTG particles must be covered by a membrane, especially when grafting larger defects, in order to control particle migration, promote clot stabilization and separate the PTG graft from undesired soft tissue cells.

关键词： bone substitutes collagen membranes critical size defects histomorphometry titanium granules

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Exploring the Association between Oral Microbiome and Mild Cognitive Impairment: A Narrative Review

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Advances in Alzheimer's Disease 2024年第2期13卷 27-34页

作者： Arghavan Tonkaboni Maryam Sayyari Pedram Khodadadzadeh Sotude Khorshidi Shaghayegh Golalipour Leyli Haghighi department of Oral Medicine School of Dentistry Tehran University of Medical Sciences Tehran Iran Grupo de Investigacion en Patologia Oral Medico Quirurgica Universidade de Santiago de Compostela Santiago de Compostela Spain Faculty of Dentistry Tehran University of Medical Sciences Tehran Iran Faculty of Dentistry Tehran Islamic Azad University Tehran Iran department of prosthodontics (Dental Branch) Islamic Azad University Tehran Iran department of Pediatrics School of Dentistry Islamic Azad University of Medical Sciences Tehran Iran

Objective: Some studies have investigated the association between oral microbiome and mild cognitive impairment (MCI). However, there needs to be more narrative reviews synthesizing this evidence. This study aimed to bridge this gap in the current knowledge. Methods: A comprehensive search was conducted on PubMed (MEDLINE) to identify studies examining the association between the oral microbiome and MCI. Search parameters and inclusion criteria were clearly defined, encompassing terms related to the oral microbiome, MCI, and their association. Two authors independently selected relevant studies and performed data extraction. Result: Four studies were included. Two cohort studies and two case-control reported an association between the oral microbiome and MCI. Conclusion: Based on the evidence synthesized from the included studies, the review suggests an association between MCI and the oral microbiome. Specifically, all included studies identified significant differences in the abundance of specific microbial species between individuals with MCI and those with normal cognitive function, underscoring the potential role of these species in neuroinflammatory diseases.

关键词： Microbiota Neurocognitive Disorders Neuroinflammations Alzheimer’s Disease Cognitive Dysfunction Neuroinflammatory Disorder

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