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Optimization of substrate ratio for beer production from finger millet and barley

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International Journal of Agricultural and biological engineering 2015年第2期8卷 110-120页

作者： Sanjay Kumar Anupama Singh Navin Chandra Shahi Khan Chand Kopal gupta department of Post-harvest process&food engineering College of TechnologyG.B.Pant University of Agriculture and TechnologyPantnagar 263145Udham Singh NagarUttarakhandIndia

Seventeen designed experiments were conducted in three steps(malting,brewing and fermentation)to produce beer from barley,finger millet and the combination of *** of independent variables with three levels for each *** ratios of grains(100:0,50:50,0:100),kilning temperature(50℃,70℃,90℃)and malted grain to water ratios(1:3,1:5,1:7)were investigated on product *** results of the study indicated that all the independent parameters *** ratio,kilning temperature and slurry ratio affected the responses(pH,colour,bitterness and alcohol content)*** values of parameters,from the simultaneous optimization done using Design Expert 8.***.6.1 software,for beer production,were found to be 68:32 blend ratio,50℃ kilning temperature and 1:7 slurry *** model F-value was found to be highly significant at 1% level of significance for all the *** the responses could be predicted by fitting the second order mathematical model and adequacy checked by R^(2).

关键词： beer production fermentation technology blend ratio alcohol content bitterness finger millet barley

Effects of moisture content and feed rate on milling characteristics of wild apricot pits (Prunus armeniaca L.)

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International Journal of Agricultural and biological engineering 2014年第1期7卷 103-110页

作者： A.E.Kate U.C.Lohani N.C.Shahi J.P.Pandey A.Sarkar Khan Chand department of Post Harvest process&food engineering College of TechnologyG.B.Pant University of Agriculture and TechnologyPantnagarU.S.Nagar(Uttarakhand)-263145India department of agricultural and biological engineering South Dakota State UniversityBrookingsSD 57006USA

Milling with decortication of wild apricot pits was done in wild apricot pit decorticator working on the principle of“impact and compression”.The milling characteristics includes decortication efficiency,percentage of husk,percentage of broken kernels and output capacity was evaluated at the different levels of moisture content,i.e.,8%,10%,12%,14%and 16%(w.b.)and feed rates,i.e.,12 g/stroke,14 g/stroke,16 g/stroke,18 g/stroke and 20 g/*** moisture content as well as feed rate significantly(Pge of husk as well as brokens and output *** efficiency was initially increased and then decreased and opposite nature was found for the percentage of *** percentage of broken kernels and output capacity decreases with the increase in moisture content,while output capacity increases with the increase in feed rate and brokens decreases with the increase in feed rate of wild apricot pits.

关键词： wild apricot pit milling characteristics decortication efficiency moisture content husk percentage broken percentage output capacity

Additivity of pore structural parameters of granular activated carbons derived from different coals and their blends

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International Journal of Mining Science and technology 2016年第4期26卷 661-667页

作者： Yao Xin Xie Qiang Yang Chuan Zhang bo Wan Chaoran Cui Shanshan School of Chemical and Environmental engineering China University of Mining and Technology department of Chemical and food engineering Hefei University of Technology

A series of granular activated carbons （gACs） were prepared by briquetting method from Chinese coals of different ranks and their blends, with coal pitch as the binder. Pore structural parameters including bET specific surface area （SbEr）, total pore volume （Vr） and average pore diameter （da） were measured and cal- culated as well as process parameters such as yield of char （CY） and burn-off （b）. The relationship between the pore structural parameters of the gAC from coal blend （bC-gAC） and the ones of the gACs from corresponding single coals （SC-gACs） was analyzed, in which an index, the relative error （δ）, was presented to define the bias between fitted values and experimental values of these parameters of the bC-gACs. The results show that the bC-gAC keeps qualitatively the pore structural features of the SC-gACs; as concerned as the quantitative relationship, the pore structural parameters of the bC-gAC from coal blend consisting of non-caking coals can be obtained by adding proportionally the pore structural parameters of the SC-gACs with a less than 10%. Meanwhile, for the bC-gAC from coal blend containing weak caking bituminous coal, the δ increases up to 25% and the experimental pore size distribution differs greatly from the fitted one.

关键词： granular activated carbon Coal blend Pore structural parameters Additivity

Computational Design of Single Mo Atom Anchored Defective boron Phosphide Monolayer as a High-performance Electrocatalyst for the Nitrogen Reduction Reaction

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Energy & Environmental Materials 2021年第2期4卷 255-262页

作者： Zaichun Liu Ting Huang Huhu Chang Faxing Wang Juan Wen Haodong Sun Masud Hossain Qingji Xie Yan Zhao Yuping Wu State Key Laboratory of Materials-Oriented Chemical engineering School of Energy Science and Engineering&Institute of Advanced MaterialsNanjing Tech UniversityNanjing 211816Jiangsu ProvinceChina State Key Laboratory of Silicate Materials for Architectures Wuhan University of TechnologyWuhan 430070China Key Laboratory of Chemical biology&Traditional Chinese Medicine Research(Ministry of Education of China) College of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081HunanChina department of Chemistry and food Chemistry&Center for Advancing Electronics Dresden(cfaed) Technische Universit¨at DresdenDresden 01062Germany

Catalytic reduction of molecular dinitrogen(N_(2))to ammonia(NH_(3))is one of the most important and challenging industrial *** reduction is considered as an energy-saving technology for artificial ambient nitrogen fixation,which is emerging as an optimal potential sustainable strategy to substitute for the Haber–bosch ***,this process demands efficient catalysts for the N_(2)reduction reaction(NRR).Here,by means of first-principles calculations,we systematically explored the potential electrocatalytic performance of single transition metal atoms(Pd,Ag,Rh,Cu,Ti,Mo,Mn,Zn,Fe,Co,Ru,and Pt)embedded in monolayer defective boron phosphide(TMs/bP)monolayer with a phosphorus monovacancy for ambient NH_(3)*** them,the Mo/bP exhibits the best catalytic performance for ambient reduction of N_(2)through the typical enzymatic and consecutive reaction pathways with an activation barrier of 0.68 e V,indicating that Mo/bP is an efficient catalyst for N_(2)*** believe that this work could provide a new avenue of ambient NH_(3)synthesis by using the designed single-atom electrocatalysts.

关键词： boron phosphide monolayer first-principles calculations nitrogen reduction reaction single-atom electrocatalysts

Efect of fermentation parameters on physicochemical and sensory properties of burans wine

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Systems Microbiology and biomanufacturing 2022年第2期2卷 380-392页

作者： Dhiraj Kumar Yadav Khan Chand Purnima Kumari department of Post-Harvest process and food engineering College of TechnologyG.B.Pant University of Agriculture and TechnologyPantnagarUttarakhand 263145India department of Agricultural engineering School of Agricultural Sciences and Rural DevelopmentCentral University of NagalandMedziphemaDimapurNagaland 797106India National Institute of food technology Entrepreneurship and Management KundliSonipatHaryana 131028India

burans is an evergreen tree that bears fowers with colors ranging from bright red to pink and are distributed throughout the *** fowers of burans exhibit many therapeutic,nutritional,and aromatic properties along with diverse health *** characteristics of burans can have a great impact on the quality of alcoholic wines and provide value addition to the burans fowers as a fermented product,which is otherwise ***,in this study,burans fowers were used for the preparation of a new favor of the wine to enhance the utility of this *** time(5,8 and 11 days),temperature(30,32 and 34℃),pH(3.5,4.0 and 4.50),and total soluble solids(TSS:22,24 and 26°bx)were varied to identify the most suitable conditions for high-quality wine *** titratable acidity,reducing sugar,pH,and TSS of burans wine were analyzed after fermentation which ranged from 0.36 to 0.78%,9.8 to 13.3%,3.43 to 4.13,and 6.9 to 16.8ºbx,*** study also provides a useful benchmark for the industrial production of burans fower wine with a standard alcohol content of 14.1%.

关键词： Rhododendron fowers burans wine Yeast Waste utilization Fermentation

Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice

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药物分析学报:英文版 2023年第8期13卷 908-925页

作者： Qiuyan guo Jiangpeng Wu Qixin Wang Yuwen Huang Lin Chen Jie gong Maobo Du guangqing Cheng Tianming Lu Minghong Zhao Yuan Zhao Chong Qiu Fei Xia Junzhe Zhang Jiayun Chen Feng Qiu Jigang Wang State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Centerand Institute of Chinese Materia MedicaChina Academy of Chinese Medical SciencesBeijing100700China School of Chinese Materia Medica and State Key Laboratory of Component-Based Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin301617China department of Nephrology Shenzhen Key Laboratory of Kidney DiseasesShenzhen Clinical Research Centre for GeriatricsShenzhen People's HospitalThe First Affiliated HospitalSouthern University of Science and TechnologyShenzhenGuangdong518020China College of food Science and engineering Institute of OceanBohai UniversityJinzhouLiaoning121013China State Key Laboratory of Infectious Disease Prevention and Control Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing102206China Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing100700China The Fourth Clinical Medical College of guangzhou university of Chinese Medicine ShenzhenGuangdong518033China

Tripterygium glycosides tablet(TgT),the classical commercial drug of Tripterygium wilfordii *** been effectively used in the treatment of rheumatoid arthritis,nephrotic syndrome,leprosy,behcet's syndrome,leprosy reaction and autoimmune ***,due to its narrow and limited treatment window,TgT-induced organ toxicity(among which liver injury accounts for about 40%of clinical reports)has gained increasing *** present study aimed to clarify the cellular and molecular events underlying TgT-induced acute liver injury using single-cell RNA sequencing(scRNA-seq)*** TgT-induced acute liver injury mouse model was constructed through short-term TgT exposure and further verified by hematoxylin-eosin staining and liver function-related serum indicators,including alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase and total *** the mouse model,we identified 15 specific subtypes of cells in the liver tissue,including endothelial cells,hepatocytes,cholangiocytes,and hepatic stellate *** analysis indicated that TgT caused a significant inflammatory response in liver endothelial cells at different spatial locations;led to marked inflammatory response,apoptosis and fatty acid metabolism dysfunction in hepatocytes;activated hepatic stellate cells;brought about the activation,inflammation,and phagocytosis of liver capsular macrophages cells;resulted in immune dysfunction of liver lymphocytes;disturbed the intercellular crosstalk in liver microenvironment by regulating various signaling ***,these findings elaborate the mechanism underlying TgT-induced acute liver injury,provide new insights into the safe and rational applications in the clinic,and complement the identification of new biomarkers and therapeutic targets for liver protection.

关键词： Tripterygium glycosides tablet Acute liver injury scRNA-seq

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biomarkers of aging

Science China(Life Sciences) 2023年第5期66卷 893-1066页

作者： Aging biomarker Consortium Hainan bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun guo Mengmeng guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen guobing Chen Hou-Zao Chen Jun Chen Weimin Ci bi-Sen Ding Qiurong Ding Feng gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou gang Pei guang-Hui Liu Aging biomarker Consortium(AbC) Beijing 100101China CAS Key Laboratory of genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China State Key Laboratory of Stem Cell and Reproductive biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410008China Hunan Key Laboratory of Aging biology Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Clinic Center of Human gene Research Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Hubei Clinical Research Center of Metabolic and Cardiovascular Disease Huazhong University of Science and TechnologyWuhan 430022China Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging Huazhong University of Science and TechnologyWuhan 430022China Stem Cell Translational Research Center Tongji HospitalTongji University School of MedicineShanghai 200065China department of Nuclear Medicine Daping HospitalThird Military Medical UniversityChongqing 400042China CAS Key Laboratory of Nutrition Metabolism and Food SafetyShanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Shanghai Key Laboratory of Maternal Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchShanghai Key Laboratory of Signaling and Disease ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China The department of Endovascular Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Regenerative Medicine of Ministry of Education Institute of Ageing and Regenerative MedicineJ

Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological *** a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly *** immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this ***,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory *** fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant.

关键词： aging senescence biomarker clock