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Functionality indexes assessed through a simple model of muscle activation, fatigue and recovery

International Journal of Biomathematics 2014年第2期7卷 189-210页

作者： Luigi Fattorini Deborah Lacitigno.a department of physiology and pharmacology university sapienza of rome piazz.le aldo moro no. 5 00185 roma Italy department of Electrical and Information Engineering university of Cassino.and Southern Lazio Via di Biasio no. 43 03043 Cassino Italy

A no.linear dynamical system is proposed as a qualitative mathematical model with the twofold aim to reasonably describe the force behavior in a fatiguing sub-maximal contraction and to be possibly employed in assessing muscular activation indexes. The model's properties are studied in terms of its equilibria and their stability properties and the existence of the fatigue equilibrium is ensured as the only system's attractor in the feasibility range of the parameters. Suitable mathematical indicators — related to the dynamical properties of resilience and reactivity — are introduced to characterize the asymptotic and the transient system's behavior. The practical impact of the analytical results is elucidated and a connection is established between the introduced mathematical indicators and muscle functionality indexes as rate of force development, task failure time and complete restore time. Experimental validation with handgrip force signal at high load and possible practical applications are also presented.

关键词：数学模型功能指标肌肉疲劳活化评估非线性动力系统受力行为

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Epidemiology of antibiotic resistance in Burkina Faso

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Asian Pacific Journal of Tropical Medicine 2008年第2期1卷 1-6页

作者： Simpore J Zeba B Karou D Ilboudo D Pignatelli S Nacoulma OG Musumeci S Saint Camille Medical Centre(SCMC) OuagadougouBurkina Faso university of Ouagadougou Burkina Faso university of rome "Tor Vergata" RomeItaly department of pharmacology Gynecology and ObstetricsPediatricsUniversity of Sassari and Institute of Biomolecular ChemistryNational Research Council(CNR)Li Punti(SS)Italy

Burkina Faso(West Africa) is a tropical country with a high incidence of infectious *** uncontrolled use of antibiotics against bacterial pathogens has given rise to the emergence of antibiotic resistance in this *** aims of this study were;i) to determine the prevalences of the most important pathogenic bacteria isolated in the town of Ouagadougou;ii) to identify the bacterial species which have acquired resistance as a result of antibiotic selection;iii) to compare antibiotic-resistances of Escherichia coli isolated from stool culture in the present study with results obtained in 2002 from strains collected in the same structure in Burkina Faso;iv) to determine the trend of antibiotic resistance in Burkina Faso in order to give local advice on the most appropriate empiric antibiotic *** thousand two hundred and sixty four samples of blood,stools, urine,sputum,pus and vaginal secretion were collected and analyzed in Saint Camille Medical Center(SCMC) laboratory from May 2001 to May *** of the 6264 samples tested no.pathogen was identified in 1583(25.31%),whilst 4681(74.73%) were positive with the incidence of the microrganisms isolated being as follows;Escherichia coli 1291(27.6%),Staphylococcus aureus 922(19.7%),Salmonella spp 561(12. 0%),Streptococcus spp 499(10.7%),Klebsiella spp 359(7.7%),Shigella spp(6.3%),Acinetobacter spp 266(5.7%) and others 783(16.7%).Among the isolated pathogens,the highest resistance was found to amoxicillin:Proteus spp 95,6%,Escherichia coli 78,2%,Salmonella spp 62,2%,Shigella spp 73,4% and Klebsiella spp 89,9%,followed by resistance to ampicillin and *** the prevalence of antibiotic resistance of Escherichia cob’from stool cultures isolated during 1999-2000 to that of 2001-2006, a significant reduction was found which could be due to the improved use of antibiotics in recent *** reduced antibiotic-resistance observed in pathogens isolated in Burkina Faso during this study as compa

关键词： Escherichia coli antibiotic-resistance Burkina Faso

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