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How we can improve patients’comfort after Milligan- Morgan open haemorrhoidectomy

World Journal of Gastroenterology 2011年第11期17卷 1448-1456页

作者： Ma-Mu-Ti-Jiang A ba-bai-ke-re Hong-Guo Huang Wen-Ni Re Kai Fan Hui Chu Er-Ha-Ti Ai Mai-Mai-Ti-Tu-Er-Xun KE Li-Mu Yi-Rui Wang Hao Wen department of Anorectal Surgical First Affiliated Hospital of Xinjiang Medical University Urumqi 830011 Xinjiang Uygur Autonomous Region China department of otolaryngeological Urumqi General Hospital Lanzhou Military Command Urumqi 830011 Xinjiang Uygur Autonomous Region China department of Pharmocological First Affiliated Hospital of Xinjiang Medi- cal University Ururnqi 830011 Xinjiang Uygur Autonomous Region China Digestive and Vascular Surgical Center First Affili. ated Hospital Xinjiang Medical University Urumqi 830011 Xinjiang Uygur Autonomous Region China

AIM:To demonstrate the value of Diosmin(flavonidic fraction)in the management of post-haemorhoidectomic ***:Eighty-six consecutive patients with grades ⅢandⅣacute mixed hemorrhoids admitted to the Anorectal Surgical department of First Affiliated Hospital,Xinjiang Medical University from April 2009 to April 2010,were enrolled in this *** observerblinded,randomized trial was conducted to compare post-haemorhoidectomic symptoms with use of Diosmin flavonidic fraction vs ***-six patients were randomly allocated to receive Diosmin flavonidic fraction 500 mg for 1 wk(n=43)or placebo(n=43).The Milligan-Morgan open haemorrhoidectomy was performed by a standardized diathermy excision ***,bleeding,heaviness,pruritus,wound edema and mucosal discharge were observed after *** postoperative symptoms and hospitalization time were ***:The mean age of the Diosmin group and controls was 53.2 and 51.3 years,*** Diosmin group,haemorrhoid piles were of the third degree in 33 patients and the fourth degree in 10;and in the control group,29 were of the third degree and 14 were of the fourth *** was no statistically significance in age,gender distribution,degree and number of excised haemorrhoid piles,and the mean duration of haemorrhoidal disease between the two *** was a statistically significant improvement in pain,heaviness,bleeding,pruritus from baseline to the 8th week after operation(P<0.05).Patients taking Diosmin had a shorter hospitalization stay after surgery(P< 0.05).There was also a significant improvement on the proctoscopic appearance(P<0.001).However,there was no statistical difference between the two groups in terms of wound mucosal *** patients experienced minor bleeding at the 8th week in Diosmin group,and underwent ***:Diosmin is effective in alleviating postoperational symptoms of ***,it should be considered for the initial treatment afte

关键词： Flavonidic fraction Postoperative complication Haemorrhoids

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