检索结果-南通市图书馆

Delayed Management of Parotid Sialocele:Role for Two-week Intraoral Drainage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2022年第4期42卷 902-904页

作者： Amin Rahpeyma Saeedeh Khajehahmadi oral&Maxillofacial Diseases Research Center Mashhad University of Medical Sciences MashhadIran department of oral and Maxillofacial Surgery School of DentistryMashhad University of Medical SciencesMashhadIran Dental Research Center Mashhad University of Medical Sciences MashhadIran department of oral and Maxillofacial pathology School of DentistryMashhad University of Medical SciencesMashhadIran

Iatrogenic injury or trauma to the salivary gland duct is one of the most common causes of parotid sialoceles,which are usually superficial,soft,and filled with *** enrolled 7 patients with parotid sialocele were divided into two groups:trauma group(4 cases)and iatrogenic group(3 cases).No evidence of recurrence or cranial nerve injuries were *** persisted parotid sialocele,intraoral drainage for two weeks as a safe and inexpensive method is recommended.

关键词： parotid gland sialocele saliva

Clinicopathological study of malignant peripheral nerve sheath tumors in the head and neck:Case reports and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界临床病例杂志 2023年第25期11卷 5910-5918页

作者： Long Li Xiao-Kun Ma Yan Gao Dian-Can Wang Rong-Fang Dong Jing Yan Ran Zhang department of oral pathology Peking University School and Hospital of StomatologyNational Clinical Research Center for Oral DiseasesNational Engineering Laboratory for Digital and Material Technology of StomatologyBeijing Key Laboratory of Digital StomatologyBeijing 100000China Research Unit of Precision Pathologic Diagnosis in Tumors of the oral and Maxillofacial Regions Chinese Academy of Medical SciencesBeijing 100000China department of oral pathology Xiangya Stomalogical Hospital&School of StomatologyCentral South UniversityChangsha 410078Hunan ProvinceChina department of oral and Maxillofacial Surgery The Affiliated Stomatological Hospital of Soochow UniversitySuzhou Stomatological HospitalSuzhou 215000Jiangsu ProvinceChina department of oral and Maxillofacial Surgery Peking University School and Hospital of StomatologyPeking University School and Hospital of StomatologyBeijing 100000China department of pathology Beijing Jishuitan HospitalBeijing 100000China

BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma that poses a major diagnostic and therapeutic *** SUMMARY We retrospectively reviewed patients with head and neck MPNSTs treated in our hospital from 2000 to *** clinical features,pathological manifestations,treatments,and prognoses were *** also reviewed the literature,focusing on MPNST in the mandible and *** study population consisted of five women and five men aged 22–75 years(mean age,49 years).Of the 10 patients,7 were initial cases and 3 were recurrent *** lesions were *** most common site was the *** most frequently encountered symptoms were a progressive mass and local *** or partial loss of trimethylation at lysine 27 of histone H3(H3K27me3)was evident on staining in four of nine cases(one case was excluded due to lack of tissue for evaluation of loss of H3K27me3).The 2-and 5-year disease-specific survival rates were 86%a nd 43%,*** average survival time was 64 *** MPNST is a highly malignant tumor with a poor prognosis,prone to a high risk of recurrence and distant *** surgical resection is the main treatment.

关键词： Malignant peripheral nerve sheath tumor Head and neck Treatment Intraosseous Surgery Case report

Mucosal healing and inflammatory bowel disease:Therapeutic implications and new targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2023年第7期29卷 1157-1172页

作者： Megan Lynn Otte Raju Lama Tamang Julia Papapanagiotou Rizwan Ahmad Punita Dhawan Amar B Singh department of pathology and microbiology University of Nebraska Medical CenterOmahaNE 68198United States department of Biochemistry and Molecular Biology University of Nebraska Medical CenterOmahaNE 68198United States

Mucosal healing(MH)is vital in maintaining homeostasis within the gut and protecting against injury and *** factors and signaling pathways contribute in a dynamic and coordinated manner to maintain intestinal homeostasis and mucosal regeneration/***,when intestinal homeostasis becomes chronically disturbed and an inflammatory immune response is constitutively active due to impairment of the intestinal epithelial barrier autoimmune disease results,particularly inflammatory bowel disease(IBD).Many proteins and signaling pathways become dysregulated or impaired during these pathological conditions,with the mechanisms of regulation just beginning to be ***,there remains a relative lack of broadly effective therapeutics that can restore MH due to the complexity of both the disease and healing processes,so tissue damage in the gastrointestinal tract of patients,even those in clinical remission,*** increased understanding of the molecular mechanisms of IBD and MH,tissue damage from autoimmune disease may in the future be ameliorated by developing therapeutics that enhance the body’s own healing *** this review,we introduce the concept of mucosal healing and its relevance in IBD as well as discuss the mechanisms of IBD and potential strategies for altering these processes and inducing MH.

关键词： Inflammation Injury/repair Mucosal healing Mucosal barrier Therapeutics Colitis

The oncofetal protein IMP3 is an indicator of early recurrence and poor outcome in mucoepidermoid carcinoma of salivary glands

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2016年第2期13卷 286-295页

作者： Mohamed R.Elshafey Rehab A.Ahmed Mohamed I Mourad Essam T.Gaballah oral pathology department Faculty of Dentistry Mansoura University pathology department Faculty of Medicine Mansoura University

Objective: Mucoepidermoid carcinoma(MEC) is the most common primary malignancy of the salivary glands. Insulin-like growth factor-II m RNA-binding protein-3(IMP3) is an important prognostic factor in some cancers and a tool that differentiates between benign and malignant pancreatic lesions. This study aimed to identify a relationship between the expression of IMP3 and the outcome of salivary gland MEC, as well as to differentiate MEC from pleomorphic adenoma(PA).Methods: Tissue specimens from 70 cases of salivary gland MEC, 40 cases of PA, and 10 cases with normal salivary gland were examined immunohistochemically for IMP3. The association among the expression of IMP3, clinicopathological characteristics and patient's survival was ***: IMP3 was present in 51.4% of MEC but absent in PA and normal salivary gland tissues. IMP3 expression was associated with age > 60 years, submandibular gland tumors, tumor size > 4 cm, high-grade tumors, lymph node metastasis, involvement of surgical margins, perineural invasion, distant metastasis, advanced TNM stage, tumor relapse, and death(P<0.05). Increased expression of IMP3, tumors of the submandibular gland, and lymph node metastasis were independent prognostic factors of disease-free survival(DFS). In addition, IMP3 was a strong predictor of overall survival(OS) together with distant metastasis and intermediate and high-grade ***: IMP3 expression is highly important in evaluating the outcome of MEC. IMP3 can be used to differentiate MEC from PA of salivary glands.

关键词：粘液表皮样癌涎腺预后复发胚蛋白胰岛素样生长因子恶性肿瘤 RNA结合蛋白

NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第5期7卷 1797-1807页

作者： Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang department of oral and Maxillofacial-Head Neck Oncology Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of Stomatology Research Unit of oral and Maxillofacial Regenerative Medicine Chinese Academy of Medical SciencesShanghaiChina department of oral and Maxillofacial Surgery Zhang Zhiyuan Academician WorkstationHainan Western Central HospitalShanghai Ninth People’s HospitalDanzhouHainanChina department of oral and Maxillofacial Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunanChina department of oral pathology Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina department of Occupational Health Third Military Medical UniversityChongqingChina department of pathology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina School of Medicine Guangxi UniversityNanningGuangxi Zhuang Autonomous RegionChina department of oral and Maxillofacial Surgery Affiliated Hospital of Guilin Medical UniversityGuilinGuangxi Zhuang Autonomous RegionChina Institute of pathology and Southwest Cancer Centre Southwest HospitalThird Military Medical UniversityChongqingChina and 10Department of Emergency MedicineFirst Affiliated Hospital and Department of Environmental MedicineSchool of Public HealthSchool of MedicineZhejiang UniversityHangzhouZhejiangChina

oral squamous cell carcinoma(OSCC)is the most common type of oral malignancy,and metastasis accounts for the poor prognosis of *** is considered to facilitate OSCC development by mitigating various cellular stresses;nevertheless,the mechanisms of autophagy in OSCC cell proliferation and metastasis remain *** our study,high-sensitivity label-free quantitative proteomics analysis revealed nuclear protein 1(NUPR1)as the most significantly upregulated protein in formalin-fixed paraffin-embedded tumour samples derived from OSCC patients with or without lymphatic metastasis.

关键词： metastasis squamous prognosis

Peltzman effect and resurgence of COVID-19 in India

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2021年第5期14卷 193-194页

作者： Simi Thankappan Sherin Nedumpillil oral Medicine&Radiology Specialist KochiKerala India department of oral pathology&microbiology Govt.Dental CollegeDibrugarhAssam India

With a daily rise of over 400000 cases,the deadly COVID-19 wave has gripped India with grim ***’s test positivity rate(TPR)was 16%with 1356133 tests[1,2](Figure 1).The number is still steeply climbing and has burdened the already overwhelmed health system.A frightening situation of lack of availability of hospital beds and critical care units has been witnessed in several states in recent days.

关键词： Figure India COV

Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of oral Science 2023年第3期15卷 390-400页

作者： Jue Wang Abigail McVicar Yilin Chen Hong-Wen Deng Zhihe Zhao Wei Chen Yi-Ping Li department of pathology School of MedicineUniversity of Alabama at BirminghamBirminghamALUSA State Key Laboratory of oral Diseases&National Center for Stomatology&National Clinical Research Center for oral Diseases&department of Orthodontics West China Hospital of StomatologySichuan UniversityChengduChina Division in Cellular and Molecular Medicine Department of Pathology and Laboratory MedicineTulane University School of MedicineTulane UniversityNew OrleansLAUSA Tulane Center of Biomedical Informatics and Genomics Deming Department of MedicineTulane University School of MedicineNew OrleansLAUSA

The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly *** found that Atp6i deficient mice(Atp6i^(−/−))arrested tooth root formation,indicated by truncated Hertwig’s epithelial root sheath(HERS)***,Atp6i deficiency significantly reduced the proliferation and differentiation of radicular odontogenic cells responsible for root ***6i^(−/−)mice had largely decreased expression of odontoblast differentiation marker gene expression profiles(Col1a1,Nfic,Dspp,and Osx)in the alveolar ***6i^(−/−)mice sample RNA-seq analysis results showed decreased expression levels of odontoblast ***,there was a significant reduction in Smad2/3 activation,inhibiting transforming growth factor-β(TGF-β)signaling in Atp6i^(−/−)*** treating pulp precursor cells with Atp6i^(−/−)or wild-type OC bone resorption-conditioned medium,we found the latter medium to promote odontoblast differentiation,as shown by increased odontoblast differentiation marker genes expression(Nfic,Dspp,Osx,and Runx2).This increased expression was significantly blocked by anti-TGF-β1 antibody neutralization,whereas odontoblast differentiation and Smad2/3 activation were significantly attenuated by Atp6i^(−/−)OC conditioned ***,ectopic TGF-β1 partially rescued root development and root dentin deposition of Atp6i^(−/−)mice tooth germs were transplanted under mouse kidney ***,our novel data shows that the prevention of TGF-β1 release from the alveolar bone matrix due to OC dysfunction may lead to osteopetrosis-associated root formation via impaired radicular odontoblast *** such,this study uncovers TGF-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation and may contribute to future therapeutic approaches to tooth root regeneration.

关键词： Smad2/3 impaired prevention

A dental perspective on the successes and limitations of the disaster victim identification response to the Nepal earthquake

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Forensic Sciences Research 2022年第3期7卷 366-370页

作者： Samarika Dahal Gopal Kumar Chaudhary Mani Raj Maharjan Eugen Dolma Walung department of oral pathology&Forensic Dentistry Maharajgunj Medical CampusInstitute of MedicineKathmanduNepal department of Forensic Medicine Maharajgunj Medical CampusInstitute of MedicineKathmanduNepal

This article describes the forensic odontological analysis of the events of the 2015 Nepal *** identifies the problems encountered in the aftermath,lessons learned,and prospective future advances aimed at reducing the subjectivity in disaster victim identification(DVI).During a crisis,dental practitioners,particularly forensic odontologists,can make a substantial contribution to DVI,as highlighted in this *** also promotes best practices in forensic dentistry that may be used by anyone in situations with few resources or people to deal with comparable scenarios.

关键词： Forensic sciences earthquake forensic dentistry identification Nepal

Towards an actionable One Health approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

贫困所致传染病(英文) 2024年第2期13卷 1-6页

作者： Zhang Xiao-Xi Lederman Zohar Han Le-Fei Schurer Janna M. Xiao Li-Hua Zhang Zhi-Bing Chen Qiu-Lan Pfeiffer Dirk Ward Michael P. Sripa Banchob Gabri?l Sarah Dhama Kuldeep Acharya Krishna Prasad Robertson Lucy J. Deem Sharon L. Aenishaenslin Cécile Dantas-Torres Filipe Otranto Domenico Grace Delia Wang Yang Li Peng Fu Chao Poeta Patrícia Rahman Md. Tanvir Kassegne Kokouvi Zhu Yong-Zhang Yin Kun Liu Jiming Wang Zhao-Jun Guo Xiao-Kui Gong Wen-Feng Schwartl?nder Bernhard Ren Ming-Hui Zhou Xiao-Nong School of Global Health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Institute of One Health Shanghai Jiao Tong University Shanghai People’s Republic of China Medical Ethics and Humanities Unit Hong Kong University Hong Kong People’s Republic of China Center for One Health University of Global Health Equity Butaro Rwanda College of Veterinary Medicine South China Agricultural University Guangzhou People’s Republic of China School of Ecology and Environment Hainan University Haikou Hainan People’s Republic of China Branch of animal and vector-borne diseases Division of Infectious Disease Control Chinese Center for Disease Control and Prevention Beijing People’s Republic of China Centre for Applied One Health Research and Policy Advice Department of Infectious Diseases and Public Health Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong Kong Hong Kong SAR People’s Republic of China department of Pathobiology and Population Sciences Royal Veterinary College London United Kingdom Sydney School of Veterinary Science The University of Sydney Camden Australia Tropical Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand Laboratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of pathology ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India department of Livestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitology Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway One Government Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidémi

Background Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the One Health Action Commission (OHAC) was established as an academic community for One Health action with an emphasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of, and motivation for, the recently formed OHAC. Recognizing the urgent need for evidence to support the formulation of necessary action plans, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial resistance, addressing food safety, and to enhance capacity building for context-sensitive One Health *** By promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.

关键词： One Health Global Health One Health Action Commission Research agenda