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One-year status of hepatic venous pressure gradient measurement from 85 hospitals in China

Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao Wang Ting Cui Linpeng Zhang Zhiping Yan Lei Li Jinjun Chen Junhui Sun Hua Xiang He Zhu Hao Wu Jiancuo Gengzang Feng Zhang Wei Wu Guohong Cao Wuhua Guo Haibin Shi Hui Xue Guangjun Huang Qiang Yu Meng Niu Huiling Xiang Derun Kong Wei Gou Xuefeng Luo Fuliang He Min Yuan Wei Liu Yong Wang Hongjie Hu Xiaoli Zhu Tao Yu Qinxue Sun Wei Qu Ting Lu Deqiang Ma Li Zhang Jun Ma Jun Yang Ketao Mu Xiaoliang Zhu Kai Xiong Huiguo Ding Shengjuan Yao Mingsheng Huang Fang Wang Zexin Wang Yong Huang Jianan Li Hongfeng Yi Birun Huang Zhongwei Zhao Duiping Feng Yanming Lei Changlong Hou Wenbo Guo Shirong Liu Gaojun Teng Kangshun Zhu Fan Wu Xiaogang Hu Wenfeng Zhang Shaoqi Yang Zhouchao Hu Pengfei Pang Shaowu Zhuang Weidong Wang Qingliang Zhu Kunpeng Zhang Chengyu Liu Dongliang Li Chao Ma Hong Jiang Xingong Zhao Weixin Ren Zhiwei Wang Lei Yu Fuhuang Lin Chaoguang Yan Feng Wang Lei Yu Hui Huan Wenyong Shen Shaofei He Chengda Zhang Jinlun Bao Jiangtao Liu Jun Wu Jianbo Zhao Jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina department of interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina department of intervention Taiyuan Third People's HospitalTaiyuanShanxiChina department of intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina department of interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina department of intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina department of intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina department of intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina department of interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina department of interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in China in ***:We investigated the overall status of HVPG technology in China-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in China used HVPG technology in 2022 distributed across 29 provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2022,of which 2813 cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2327.9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82/87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in China and confirmed that some medical institutions in China have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey

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microRNAs and ceRNAs: RNA networks in pathogenesis of cancer

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Chinese Journal of Cancer Research 2013年第2期25卷 235-239页

作者： Xiangqian Su Jiadi Xing Zaozao Wang Lei Chen Ming Cui Beihai Jiang Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Minimally Invasive Gastrointestinal Surgery Peking University Cancer Hospital & Institute

microRNAs （miRNAs） are a class of endogenous, single-stranded non-coding RNAs of 20- 23 nucleotides in length, functioning as negative regulators of gene expression at the post-transcriptional level. The dysregulation of miRNAs has been demonstrated to play critical roles in tumorigenesis, either through inhibiting tumor suppressor genes or activating oncogenes inappropriately. Besides their promising clinical applications in cancer diagnosis and treatment, recent studies have uncovered that miRNAs could act as a regulatory language, through which messenger RNAs, transcribed pseudogenes, and long noncoding RNAs crosstalk with each other and form a novel regulatory network. RNA transcripts involved in this network have been termed as competing endogenous RNAs （ceRNAs）, since they influence each other＇s level by competing for the same pool of miRNAs through miRNA response elements （MREs） on their target transcripts. The discovery of miRNA-ceRNA network not only provides the possibility of an additional level of post-transcriptional regulation, but also dictates a reassessment of the existing regulatory pathways involved in cancer initiation and progression.

关键词： miRNA ceRNA cancer

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Hydrochloric acid-enhanced radiofrequency ablation for treating a large hepatocellular carcinoma with spontaneous rapture:a case report

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Chinese Journal of Cancer 2017年第1期36卷 44-49页

作者： Ru-Hai Zou Yang-Kui Gu Fei Gao Tian-Qi Zhang Wang Yao Xiong-Ying Jiang Yan-Yang Zhang department of minimally invasive interventional Therapy Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer Medicine department of Oncologic interventional Therapy The First Affiliated Hospital Sun Yat-sen University department of Radiology intervention Sun Yat-sen Memorial Hospital Sun Yat-sen University department of intervention The Third Affiliated Hospital Sun Yat-sen University

Background:A ruptured hepatocellular carcinoma(HCC)is often *** addition to surgery and transarterial embo?lization,radiofrequency ablation(RFA)might be another option for treating a ruptured ***,conven?tional RFA has a limited ablation zone;as such,it is rarely used to treat ruptured *** presentation:This case was a 60?year?old man who had a large,ruptured HCC in which hydrochloric acid(HCl)?enhanced RFA successfully controlled the bleeding and made the tumor completely ***:Considering the effectiveness of HCl?enhanced RFA in achieving hemostasis and tumor ablation,it might be a new option for treating large,ruptured HCCs.

关键词： Hydrochloric acid Radiofrequency ablation Spontaneous rupture Hepatocellular carcinoma

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Silicon nanoparticles: Preparation, properties, and applications

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Chinese Physics B 2014年第8期23卷 23-36页

作者：常欢孙树清 Shenzhen Key Laboratory for minimally invasive Medical Technologies Graduate School at Shenzhen Tsinghua University department of Biomedical Engineering Tsinghua University

Silicon nanoparticles have attracted great attention in the past decades because of their intriguing physical properties, active surface state, distinctive photoluminescence and biocompatibility. In this review, we present some of the recent progress in preparation methodologies and surface functionalization approaches of silicon nanoparticles. Further, their promising applications in the fields of energy and electronic engineering are introduced.

关键词： silicon nanoparticle quantum confinement effect optical performance

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Complete mesocolic excision and central vascular ligation in colorectal cancer in the era of minimally invasive surgery

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World Journal of Clinical Cases 2021年第25期9卷 7297-7305页

作者： Marzia Franceschilli Sara Di Carlo Danilo Vinci Bruno Sensi Leandro Siragusa Vittoria Bellato Roberto Caronna Piero Rossi Giuseppe Cavallaro Andrea Guida Simone Sibio department of Surgery Minimally Invasive UnitTor Vergata University of RomeRome 00133Italy department of Surgical Sciences Unit of Pancreatic and Biliary SurgerySapienza University of RomeRome 00161Italy department of Surgery P Valdoni Unit of Oncologic and Minimally Invasive SurgerySapienza University of RomeRome 00161Italy

Since the 19th century,appropriate lymphadenectomy has been considered a cornerstone of oncologic surgery and one of the most important prognostic *** approach can be applied to any surgery for gastrointestinal *** surgery for colon and rectal cancer,an adequate portion of the mesentery is removed together with the segment of bowel affected by the *** adequate number of lymph nodes to be removed is standardized and reported by several *** is mandatory to determine the appropriate extent of lymphadenectomy and to balance its oncological benefits with the increased morbidity associated with its execution in cancer *** review focuses on the concept of“complete mesenteric excision(CME)with central vascular ligation(CVL),”a radical lymphadenectomy for colorectal cancer that has gained increasing interest in recent *** aim of this study was to evaluate the evolution of this approach over the years,its potential oncologic benefits and potential risks,and the improvements offered by laparoscopic *** advantages of CME are improved local-relapse rates due to complete removal of the intact mesocolic fascia and improved distance recurrence rates due to ligation of vessels at their origin(CVL)which guarantees removal of a larger number of lymph *** development and worldwide diffusion of laparoscopic techniques minimized postoperative trauma in oncologic surgery,providing the same oncologic results as open *** has been widely applied to colorectal cancer surgery;however,CME entails a technical complexity that can limit its wide minimally-invasive application. This review analyzesresults of these procedures in terms of oncological outcomes, technical feasibilityand complexity, especially within the context of minimally invasive surgery.

关键词： Complete mesenteric excision Central vascular ligation Colorectal cancer Lymphadenectomy Laparoscopy minimally invasive surgery

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The use of botulinum toxin A in chemical component separation: a review of techniques and outcomes

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Plastic and Aesthetic Research 2020年第4期7卷 1-9页

作者： Sharbel A.Elhage Eva B.Deerenberg Jenny M.Shao Vedra A.Augenstein B.Todd Heniford department of Gastrointestinal and minimally invasive Surgery Carolinas Medical CenterCharlotteNC 28204USA

Fascial closure is crucial for abdominal wall reconstruction (AWR) but can be especially difficult in patients with massive ventral hernias or loss domain. Recently, botulinum toxin A (BTA) has been increasingly utilized as an adjunct in AWR to aid in fascial closure. This review aims to evaluate the current literature on the use of BTA in AWR to assess current treatment regimens, side effects, outcomes and complications. A literature search was performed, yielding 10 studies that met the inclusion criteria. There was a significant amount of heterogeneity in treatment regimens, with studies differing in BTA injection timing, dosage, concentration, and location. The majority of studies showed that injection of BTA preoperatively was able to augment abdominal wall musculature, with many showing a decrease in mean transverse defect size and high rates of successful fascial closure. No major complications were reported from BTA administration, with only mild side effects reported by some studies. The most common side effects include a weak cough or sneeze, bloating, and back pain, which generally all resolved prior to surgery. While BTA appears to be a promising adjunct for AWR, further investigation is needed to determine optimal patient selection and treatment regimens.

关键词： Hernia abdominal wall reconstruction botulinum toxin botox chemical component separation

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Percutaneous transgastric endoscopic tube ileostomy in a porcine survival model

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World Journal of Gastroenterology 2016年第37期22卷 8375-8381页

作者： Hong Shi Su-Yu Chen Yong-Guang Wang Sheng-Jun Jiang He-Li Cai Kai Lin Zhao-Fei Xie Fen-Fang Dong department of Gastro- intestinal Endoscopy Fujian Provincial Cancer Hospital Affiliated Cancer Hospital of Fujian Medical University department of minimally invasive Surgery Beijing Chuiyangliu Hospital Institute of Minimally Invasive Medicine of Tongji University department of Gastroenterology Fuzhou Seventh Hospital department of General Surgery Fuzhou Seventh Hospital Faculty of Medical Technology and Engineering Fujian Medical University

AIM To introduce natural orifice transgastric endoscopic surgery(NOTES) tube ileostomy using pelvis-directed submucosal tunneling endoscopic gastrostomy and endoscopic tube *** Six live pigs(three each in the non-survival and survival groups) were used. A double-channeled therapeutic endoscope was introduced perorally into the stomach. A gastrostomy was made using a 2-cmtransversal mucosal incision following the creation of a 5-cm longitudinal pelvis-directed submucosal tunnel. The pneumoperitoneum was established via the endoscope. In the initial three operations of the series, a laparoscope was transumbilically inserted for guiding the tunnel direction, intraperitoneal spatial orientation and distal ileum identification. Endoscopic tube ileostomy was conducted by adopting an introducer method and using a Percutaneous Endoscopic Gastrostomy Catheter Kit equipped with the Loop Fixture. The distal tip of the 15 Fr catheter was placed toward the proximal limb of the ileum to optimize intestinal content drainage. Finally, the tunnel entrance of the gastrostomy was closed using nylon endoloops with the aid of a twin grasper. The gross and histopathological integrity of gastrostomy closure and the abdominal wall-ileum stoma tract formation were assessed 1 wk after the *** Transgastric endoscopic tube ileostomy was successful in all six pigs, without major bleeding. The mean operating time was 71 min(range: 60-110 min). There were no intraoperative complications or hemodynamic instability. The post-mortem, which was conducted 1-wk postoperatively, showed complete healing of the gastrostomy and adequate stoma tract formation of *** Transgastric endoscopic tube ileostomy is technically feasible and reproducible in an animal model, and this technique is worthy of further improvement.

关键词： Natural orifice transluminal endoscopic surgery Tube ileostomy Endoloop Pigs Submucosal tunneling

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Matched-pair analysis of postoperative morbidity and mortality for pancreaticogastrostomy and pancreaticojejunostomy using mattress sutures in soft pancreatic tissue remnants

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Hepatobiliary & Pancreatic Diseases International 2012年第1期11卷 89-95页

作者： Fritz Klein Marcus Bahra Matthias Glanemann Wladimir Faber Peter Warnick Andreas Andreou Safak Gül Dietmar Jacob department of General Visceraland Transplantation SurgeryCharité-Campus VirchowUniversit tsmedizin Berlin department of Visceral Vascularand Minimally Invasive SurgeryVivantes Klinikum Spandau

BACKGROUND:After pancreaticoduodenectomy,the incidence of postoperative pancreatic fistula remains high,especially in patients with 'soft' pancreatic tissue *** 'gold standard' surgical technique for pancreaticoenteric anastomosis has been *** study aimed to compare the postoperative morbidity and mortality of pancreaticogastrostomy and pancreaticojejunostomy for 'soft' pancreatic tissue remnants using modified mattress ***:Seventy-five patients who had undergone pancreaticogastrostomy and 75 who had undergone pancreaticojejunostomy after pancreaticoduodenectomy between 2002 and 2008 were retrospectively compared using matched-pair analysis.A modified mattress suture technique was used for the pancreaticoenteric *** with an underlying 'hard' pancreatic tissue remnant,as in chronic pancreatitis,were *** groups were homogeneous for age,gender,and underlying *** morbidity,mortality,and preoperative and operative data were ***:There were no significant differences between the groups for the incidence of postoperative pancreatic fistula (10.7% in both).Postoperative morbidity and mortality,median operation time,median length of hospital stay,intraoperative blood loss,and the amount of intraoperatively transfused erythrocyte concentrates also did not significantly differ between the *** age >65 years (P=0.017),operation time >350minutes (P=0.001),and intraoperative transfusion of erythrocyte concentrates (P=0.038) were identified as risk factors for postoperative ***:Our results showed no significant differences between the groups in the pancreaticogastrostomy and pancreaticojejunostomy anastomosis techniques using mattress sutures for 'soft' pancreatic tissue *** our experience,the mattress sutures are safe and simple to use,and pancreaticogastrostomy in particular is feasible and easy to learn,with good endoscopic accessibility to the anastomos

关键词： mattress sutures pancreaticoduodenectomy pancreaticogastrostomy pancreaticojejunostomy soft pancreatic tissue remnant

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Comment on:“Completion pancreatectomy or a pancreas-preserving procedure during relaparotomy for pancreatic fistula after pancreatoduodenectomy:a multicentre cohort study and meta-analysis”

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Hepatobiliary Surgery and Nutrition 2022年第1期11卷 94-96页

作者： Régis Souche Jean-Michel Fabre department of Oncologic and minimally invasive Digestive Surgery Hospital Saint EloiUniversity Hospital of MontpellierMontpellierFrance

We read with great interest the recently published article of Groen et *** the Dutch Pancreatic Cancer Group(1)appeared on British Journal of *** authors compared salvage completion pancreatectomy with a pancreas-preserving procedure in patients undergoing relaparotomy for severe pancreatic fistula after pancreatoduodenectomy(PD).This retrospective multi center cohort study included patients who underwent relaparotomy for pancreatic fistula after PD from 2005-2018 and provided a systematic review with a meta-analysis on postoperative *** the literature,large retrospective studies dedicated to this question are rare and no randomized study is available to date.

关键词： pancreas fistula

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Establishing a center of excellence in abdominal wall reconstruction

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Plastic and Aesthetic Research 2020年第4期7卷 63-72页

作者： Jenny Shao Sharbel Elhage Eva Deerenberg Vedra Augenstein B.Todd Heniford Gastrointestinal and minimally invasive Surgery Department of SurgeryCarolinas Medical CenterCharlotteNC 28204USA

Building a tertiary referral center of excellence for complex abdominal wall reconstruction is a multi-step process that requires many elements to garner and promote *** the creation of such a center is important for continual improvement of abdominal wall reconstruction outcomes by decreasing complications,recurrences,length of hospital stay,hospital readmissions,and overall *** a center of excellence incorporates several key components including the surgeon's desires and expertise,institutional participation,multidisciplinary collaboration,outcomes research and innovation,and financial *** article outlines the principal elements of building a sustainable,functional,and successful center of excellence for complex abdominal wall reconstruction.

关键词： Complex abdominal wall reconstruction center of excellence

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