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Anti-enteric bacterial activity of the traditional medicinal plants of Kanyakumari coast,Tamilnadu,India

Journal of Coastal Life Medicine 2015年第8期 640-644页

作者： Suyambu Rajan Parameshwaran Suvetha Thiyagarajan Thirunalasundari Solomon Jeeva department of microbiology M.R.Government Arts CollegeMannargudi-614001Thiruvarur DistrictTamilnaduIndia department of microbiology Srimad Andavan Arts and Science CollegeThiruvanai KoilTiruchirappalli-620005TamilnaduIndia department of Biotechnology Bharathidasan UniversityTiruchirappalli-620024TamilnaduIndia department of Botany Scott Christian CollegeNagercoil-629003KanyakumariTamilnaduIndia

Objective:To evaluate the antimicrobial potentials of 6 traditionally used medicinal plants to treat gastrointestinal infection against pathogenic bacteria,as most of the pathogens develop drug resistance against commonly used ***:Crude extracts from different parts of different plants were tested against bacterial strains of clinical *** of bioactive principles was done with water and *** of antibacterial activity was done by disc diffusion assay against selected bacterial ***:Of the 6 different plant materials tested,extracts prepared from Psidium guajava leaves showed significantly higher *** prepared using alcohol exhibited higher antibacterial activity when compared to their corresponding aqueous ***:The findings of the present study suggested that phytochemical extracts of the presently studied plant materials possess significant anti-enteric bacterial activity,and thus lend pharmacological credibility to the suggested traditional use of the plant as a natural remedy for the treatment,management and/or control of gastrointestinal diseases in the coastal tracts of Kanyakumari district,Tamilnadu,India.

关键词： Antibacterial activity Disc diffusion assay Enteric bacteria Plant extracts

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Evaluation of antibacterial potential of seaweeds occurring along the coast of Mandapam,India against human pathogenic bacteria

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Journal of Coastal Life Medicine 2014年第3期 196-202页

作者： Gopalraj Karthikai Devi Karunamoorthy Manivannan Perumal Anantharaman department of Zoology D.G.G.Arts College for WomenMayiladuthuraiTamil Nadu-609001India Division of Microbial Biodiversity and Bioenergy Department of MicrobiologyBharathidasan UniversityTiruchirapalliTamilnadu-620024India Centre of Advanced Study in Marine Biology Faculty of Marine SciencesAnnamalai UniversityParangipettaiTamilnadu–608502India

Objective:To investigate the antibacterial activity of six seaweeds against twelve human bacterial pathogens using seven different ***:Antibacterial activity was evaluated using the disc diffusion technique on Mueller Hinton *** dilution assays are standard method used to compare the inhibition efficiency of the antimicrobial ***:Among the six seaweeds tested,the antibacterial activity was higher in the brown seaweeds when compared to red and green *** gymnospora was found exerting a strong antibacterial activity with a high range inhibition[(6.00±0.82)to(22.67±1.25)mm].Broth dilution assay was conducted against Salmonella *** the chloroform extract of Padina gymnospora and the growth inhibition was found in the range of 74.26%to 82.56%.Conclusions:Further research studies are being carried out on other species of seaweeds of different habitats in order to provide complete data of the antimicrobial potential of these *** is also essential to study the principle compound present in the seaweeds which is responsible for antimicrobial *** can be achieved by using advanced separation techniques.

关键词： Antibacterial Seaweeds Mandapam Human pathogenic bacterium Different extracts

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Assessment of non-steroidal anti-inflammatory drugs from selected wastewater treatment plants of Southwestern India

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Emerging Contaminants 2021年第1期7卷 43-51页

作者： Yerabham Praveenkumarreddy Krishnamoorthi Vimalkumar Babu Rajendran Ramaswamy Virendra Kumar Rakesh Kumar Singhal Hirakendu Basu Chikmagalur Mallappa Gopal Kalwaje Eshwara Vandana Krishnamurthy Bhat Harikripa Narayana Udayashankar Keshava Balakrishna department of Civil Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipal576104India Ecotoxicology and Toxicogenomics Lab Department of Environmental BiotechnologySchool of Environmental SciencesBharathidasan UniversityTiruchirappalli620024Tamil NaduIndia Radiation Technology Development Division(RTDD) Bhabha Atomic Research CentreTrombayMumbai400085India Analytical Chemistry Division Bhabha Atomic Research CentreTrombayMumbai400085India department of microbiology Kasturba Medical CollegeManipal Academy of Higher EducationManipal576104India department of Pharmaceutical Quality Assurance Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipal576104India

Non-steroidal anti-inflammatory drugs(NSAIDs)(aspirin,ibuprofen,naproxen,ketoprofen,and diclofenac)were determined in three selected wastewater treatment plants(WWTPs)in southwestern India and the Gurupura *** concentrations of the NSAIDs in the influents of the WWTPs ranged 125-184 mg/L for aspirin,5e22 mg/L for ibuprofen,11-217 mg/L for naproxen,3-41 mg/L for ketoprofen and 12-68 mg/L for *** the effluents,concentrations ranged 0.4-0.7 mg/L for aspirin,0.1-2 mg/L for ibuprofen,3-14 mg/L for naproxen,0.6-0.8 mg/L for ketoprofen and 2-26 mg/L for *** NSAIDs in the WWTPs were found in the order of aspirin>naproxen>diclofenac>ketoprofen>*** the Gurupura river,aspirin(0.02 mg/L),ibuprofen(0.17 mg/L),naproxen(8.8 mg/L),ketoprofen(1.5 mg/L)and diclofenac(1.6 mg/L)were *** quotient(HQ)for various aquatic organisms were calculated for the effluents of WWTPs and Gurupura river *** results showed medium risk of ibuprofen and naproxen to polyp Hydra *** discharge of NSAIDs into the river can result in adverse effects to the resident organisms.

关键词： NSAIDs Wastewater GC MS Hazard quotient Risk assessment Aquatic environment

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