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Psychological burden of food allergy

World Journal of Gastroenterology 2007年第25期13卷 3456-3465页

作者： Martin Teufel Tilo Biedermann Nora Rapps Constanze Hausteiner Peter Henningsen Paul Enck Stephan Zipfel department of internal medicine vi -psychosomatic medicine and psychotherapy University of Tübingen Tübingen 72076 Germany department of Dermatology University of Tübingen Tübingen 72076 Germany department of psychosomatic medicine University Hospital Technical University Munich 81675 Germany

One fifth of the population report adverse reactions to food. Reasons for these symptoms are heterogeneous, varying from food allergy, food intolerance, irritable bowel syndrome to somatoform or other mental disorders. Literature reveals a large discrepancy between truly diagnosed food allergy and reports of food allergy symptoms by care seekers. In most studies currently available the characterization of patient groups is incomplete, because they did not distinguish between immunologic reactions and other kinds of food reactions. In analysing these adverse reactions, a thorough physical and psychological diagnostic approach is important. In our qualitative review, we present those diagnostic measures that are evidenced-based as well as clinically useful, and discuss the various psychological dimensions of adverse reactions to food. It is important to acknowledge the complex interplay between body and mind： Adults and children suffering from food allergy show impaired quality of life and a higher level of stress and anxiety. Pavlovian conditioning of adverse reactions plays an important role in maintaining symptoms. The role of personality, mood, or anxiety in food reactions is debatable. Somatoform disorders ought to be identified early to avoid lengthy and fiustrating investigations. A future task will be to improve diagnostic algorithms, to describe psychological aspects in clearly characterised patient subgroups, and to develop strategies for an optimized management of the various types of adverse reactions to food.

关键词： Food allergy Food reactions Diagnostic measures Psychological aspects Quality of life

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The psyche and the gut

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World Journal of Gastroenterology 2007年第25期13卷 3405-3408页

作者： Paul Enck Ute Martens Sibylle Klosterhalfen University Hospitals Tübingen Department of Internal Medicine Ⅵ Psychosomatic Medicine and Psychotherapy Germany

Research on gut-brain interactions has increased over the last decade and has brought about a number of new topics beyond ＂classical＂ subjects, such as ＂stress＂ and personality; which have dominated the psychosomatic literature on gastrointestinal disorders over the past century. These novel topics include brain imaging of intestinal functions, placebo responses in gastroenterology, learning of gastrointestinal symptoms, quality of life in patients with intestinal complaints, and psychotherapy and familial aggregation of functional intestinal disorders. Currently, these new topics appear with a frequency of 1% to 3% in leading gastroenterological journals, either as data presentation or review papers. Increasing focus underlines the importance of enhandng our understanding on how the psyche and the brain communicate in order to better meet the needs of our patients.

关键词： Gut-brain interactions Psyche Functionalbowel disorders Irritable bowel syndrome

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Psychosocial issues in evidence-based guidelines on inflammatory bowel diseases: A review

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World Journal of Gastroenterology 2014年第13期20卷 3663-3671页

作者： Winfried Huser Gabriele Moser Petra Klose Antonina Mikocka-Walus department of internal medicine Ⅰ Klinikum SaarbrückenD-66119 SaarbrückenGermany department psychosomatic medicine and psychotherapy Technische Universit?t MünchenD-81675 MünchenGermany department of internal medicine Ⅲ Division of Gastroenterology and HepatologyMedical University of Vienna1090 ViennaAustria department internal medicine Ⅴ (Integrative medicine) Kliniken Essen-MitteEssenD-45276 EssenGermany department of Health Sciences University of YorkHeslingtonYorkYO105DDUnited Kingdom

AIM: To study statements and recommendations on psychosocial issues as presented in international evidence-based guidelines on the management of inflammatory bowel diseases (IBD).

关键词： Anxiety Depression Guidelines Inflammatory bowel diseases Psychological psychotherapy Smoking Stress

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Psychiatric comorbidities in cancer survivors across tumor subtypes:A systematic review

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World Journal of Psychiatry 2022年第4期12卷 623-635页

作者： Anne Bach Klara Knauer Johanna Graf Norbert Schäffeler Andreas Stengel Section Psychooncology Department of Psychosomatic Medicine and PsychotherapyUniversity Hospital TübingenTübingen 72076Germany Germany&CharitéCenter for internal medicine and Dermatology Department for Psychosomatic MedicineCharite-Universitätsmedizin BerlinCorporate Member of Freie Universität BerlinHumboldt-Universität zu Berlin and Berlin Institute of HealthBerlin 10117Germany

BACKGROUND Psychiatric disorders are common but underdiagnosed in cancer *** suggests that tumor type has an effect on the prevalence of clinically relevant depression,anxiety,comorbid anxiety-depression and posttraumatic stress disorder(PTSD).AIM To identify studies that examined the prevalence of clinically relevant levels of depression,anxiety,comorbid anxiety-depression and PTSD for patients with one or more tumor sites and compare those prevalences between cancer *** Four databases(PubMed,PsycInfo,PubPsych and the Cochrane Database)were searched and resulted in a total of 2387 articles to be *** be included,a study must have investigated cancer-free and posttreatment survivors using tools to assess clinically relevant levels of the listed psychiatric *** articles were screened by two authors with a third author reviewing debated *** Twenty-six studies on ten different tumor types fulfilled all inclusion criteria and were included in the *** studies showed heterogeneity regarding the study characteristics,number of participants,time since diagnosis,and assessment ***,all four comorbidities show higher prevalences in cancer survivors than the general *** tumor survivors were reported to have a relatively high prevalence of both depression and *** with melanoma survivors reported high prevalences of all four psychiatric *** comorbidities,a wide range in prevalence existed across the tumor *** one cancer site,the prevalence also varied considerably among the *** Psychiatric comorbidities are more frequent in cancer survivors than in the general population,as reflected by the prevalence of depression,anxiety,comorbid anxiety-depression and PTSD across all tumor *** generalized screening tools that examine psychological distress in cancer survivors up to at least ten years after diagnosis could help to

关键词： Cancer survivor Cancer type Prevalence Psychiatric disorder Psychiatric comorbidity Survivorship Tumor site

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Altered attentive bias towards interpersonal communication information across phases of schizophrenia: an eye-tracking study

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General Psychiatry 2022年第2期35卷 119-126页

作者： Yikang Zhu Lihua Xu Qian Guo Tianhong Zhang Xiaochen Hu Paul Enck Jijun Wang Chunbo Li Shanghai Key Laboratory of Psychotic Disorder Shangai Mental Heath CenterShanghai Jiao Tong University School of MedicineShanghaiChina department of Psychiatry and psychotherapy Medical FacultyUniversity of ColognenCologneGermany department of Interal medicine vi:psychosomatic medicine and psychotherapy University Hospital TubingenTubingenGermany CAS Center for Excellence in Brain Science and Intelligence Technology(CEBSIT)Chinese Academy of Sciences ShanghaiChina Institute of Psychology and Behavioral Science Shanghai Jiao Tong UniversityShanghaiChina

Background Eye movement abnormality in schizophrenia has been studied for several ***,patient differences in eye movements across phases of schizophrenia from eye-tracking studies have not been well *** This pilot study used eye-tracking technology to investigate attentive bias towards interpersonal communication information across different clinical phases of *** This study included 78 persons at clinical high risk(CHR)for schizophrenia,68 first-episode(FEZ)patients,and 39 chronically ill patients from the Shanghai At Risk for Psychosis Extending Project(SHARP Extending cohort)as well as 74 healthy controls(HCs).The experiment was an unguided-viewing task composed of 24 trials showing three types of pictures which varied in the degree of interpersonal *** 1 was a scenery picture without people,type 2 was a picture with four people not communicating,and type 3 was a picture with four people *** used two measures:(1)initial fixation duration and(2)total fixation *** A ratio for both measures was calculated between measures for pictures with more or less interpersonal *** ratio of initial fixation duration for pictures with people communicating versus pictures with people not communicating was lowest in chronically ill patients(0.13(0.34))compared with HCs(0.31(0.36)),FEZ patients(0.31(0.46)),and CHR patients(0.36(0.42)).The difference in the ratios of initial fixation duration for type 2 and type 3 pictures was also significant for female participants(HCs vs chronically ill patients,t=2.706,p=0.009;CHR patients vs chronically ill patients,t=4.079,p<0.001).In addition,the ratio of initial fixation duration on pictures with people not communicating versus pictures without people negatively correlated with participants’high-risk symptoms(r=−0.35,p=0.002)among the CHR group and also correlated with the negative symptom subscore on the Positive and Negative Syndrome Scale(PANS

关键词： schizophrenia communication measures

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Sleep Duration and Sleep Problems in a Representative Sample of German Children and Adolescents

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Health 2015年第11期7卷 1397-1408页

作者： Angelika A. Schlarb Marco D. Gulewitsch victoria Weltzer Ute Ellert Paul Enck department of Psychology and Sports University of Bielefeld Bielefeld Germany Faculty of Science Department of Psychology University of Tuebingen Tuebingen Germany department of Epidemiology Health Monitoring Robert Koch-Institute Berlin Germany department of internal medicine vi: psychosomatic medicine and psychotherapy University Hospital Tuebingen Germany

Objective: The main purpose of the present study was to evaluate sleep duration for nighttime sleep from early infancy to late adolescence in a German sample to illustrate the developmental course and age-specific variability of these variables among subjects. Methods: A total of 17,641 subjects from the KiGGS study were evaluated. The questionnaires contained questions about physical health, living circumstances, health behavior and risks, health supply, mental health, health-related quality of life and sleep. KiGGS assessed sleep by using parent questionnaire of children aged 0 to 10 years (n = 9944) and self-reports of adolescents (n = 7697) aged 11 to 17 years. Results: Total sleep duration decreased from 14.28 hours (SD = 2.33) at the ages 0 - 0.5 to 9.50 hours (SD = 0.82) at the ages of 10.5 - 11. Above the age of 11 adolescents report a decrease of sleep at night from 9.41 hours (SD = 1.33) at the age of 11 - 11.5 to 7.42 (SD = 1.73) at the age of 17.5 - 18 years. Unspecified sleep problems were reported of 19.5%, 13.0% of the children had difficulties falling asleep, difficulties sleeping through the night showed 8.8% of the children, whereas 3.0% report both symptoms—difficulties falling asleep and difficulties sleeping through the night. Conclusions: Age-specific variability of sleep duration is reported as well as sleep difficulties from infancy to adolescence. This is important knowledge for the health care professional who deals with sleep problems in pediatric practice.

关键词： Sleep Duration Infants Children Adolescents Sleep Problems

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