检索结果-南通市图书馆

Valorization of malaysian tropical fruit seeds: A review of their nutrition, bioactivity, processing and food application

在线全文

学校读者我要写书评

暂无评论

food Bioscience 2022年第6期50卷 2023-2034页

作者： Anis Nashuha Md Sani Noranizan Mohd Adzahan Mohammad Rashedi Ismail-Fitry department of food technology Faculty of Food Science and TechnologyUniversiti Putra Malaysia 43400 UPM SerdangMalaysia

malaysia produces varieties of tropical fruits such as durian, rambutan, jackfruit, mango, papaya, and mangosteen but the seeds are considered waste. The seeds contain beneficial nutrients such as protein, carbohydrates, fat, and minerals, and have high bioactive properties. Various processing methods have been applied to extract the seeds and apply them to the food system. The information is scattered and incomprehensive, therefore, this paper aims to review the chemical properties and biological activities of the selected tropical fruit seeds, and their processing and functional properties to the food. Most seeds are rich in carbohydrates but also contain various minerals and fatty acids. The antioxidant, antidiabetic, anti-bacterial/anti-fungal, anti-inflammatory, anti-hyper cholesterol and anti-proliferative properties were also reported with rambutan and papaya seeds having the most bioactive properties. Novel and conventional extraction methods of the seeds, the functionality of the seeds to improve the food such as pasting and emulsifying properties, and their effect on the colour, texture, sensory and storage stability were also highlighted. In summary, all the selected seeds have the potential to be upcycled as food ingredients as they contain various nutrients while providing therapeutic and functional properties, however, further research can be considered to optimize the seeds' usability.

关键词： food ingredients Fruit waste Seeds extraction Seeds composition Seeds toxicity

Identification of commonly regulated genes in HPV18-and HPV16-infected cervical cancer cells treated with the curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2018年第1期8卷 44-51页

作者： Felicia Paulraj Faridah Abas Nordin H.Lajis Iekhsan Othman Sharifah Syed Hassan Rakesh Naidu Jeffrey Cheah School of Medicine & Health sciences Monash University Malaysia Laboratory of Natural Products Faculty of Science Universiti Putra Malaysia department of food science Faculty of Food Science and Technology Universiti Putra Malaysia

Objective: To identify commonly regulated genes in HPV-infected He La and Ca Ski cervical cancer cells treated with curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one(MS17) and to explore potential mechanisms that underlie its cytotoxic, anti-proliferative and apoptotic activity. Methods: He La and Ca Ski cells were treated with 2×EC50 and 3×EC50 doses of MS17 for 24 h and the RNA extracts were subjected to one-colour microarray-based gene expression profiling. Pair-wise significant genes(false discovery rate-corrected, P<0.05) were analysed for fold change(FC) compared to control samples. Differentially expressed genes with FC≥2.0(up-regulated; FC≥2.0 and down-regulated; FC≤-2.0) compared to the control samples were filtered through and analysed to create a global gene expression profile. Mutually regulated genes were ranked by FC and categorised by gene ontology. Results: Our data indicated dose-dependent regulation by MS17 and identified top 20 mutually upand down-regulated genes each in He La and Ca Ski cells. Amongst these 17 were commonly regulated in both cell lines. These include the up-regulation of CCL26, DEFB103 B, IL1 RL1, LY96, GCNT3, MMP10, MMP3, GADD45 G and HSPA6, and the down-regulation of TENM2, NEBL, KIFC1, CTDSP1, IGFBP5, LTBP1, NREP and MXD3. These genes were associated with key biological functions that were proposed to mediate the anticancer activity of MS17 in cervical cancer cells such as immune response, metabolic processes, proteolysis, programmed cell death, unfolded protein response, cell adhesion, cytoskeletal organisation, phosphatase activity, signal transduction and transcription regulator activity. Conclusions: Identification of seventeen common genes modulated by MS17 could be used as potential therapeutic targets in both cervical cancer cell lines and the findings of this study could be used to present an insight into the potential antitumor activity of MS17 in cervical cancer.

关键词： Diarylpentanoid Cervical cancer Gene expression profiling Microarray Curcumin analogue

Anti-hypercholesterolemic effect of kenaf(Hibiscus cannabinus L.)seed on high-fat diet Sprague dawley rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2015年第1期8卷 6-13页

作者： Ng Shy Kai Tee Ai Nee Elaine Lai Chia Ling Tan Chin Ping Long Kamariah Nyam Kar Lin department of food science and Nutrition Faculty of Applied SciencesUCSI University department of food technology Faculty of Food Science and TechnologyUniversiti Putra Malaysia malaysian Agricultural Research & Development Institute

Objective:To determine? the anlihypercholesterolemic effects of kenaf seed samples and compare with the commercial hypocholesterolemic drug on serum lipids profiles and malondialdehyde(MDA) level in the ***:Kenaf seed oil(KSO),microencapsulated kenaf seed oil(MKSO),kenaf seed extract(KSE) and defatted kenaf seed meal(DKSM) were prepared and phytocHemicals screening on these samples were done prior in viro *** compounds in *** quantified using high performance liquid *** were 40(divided in eight diet groups of 5) male Sprague dawley rats adapted lo normal standard diet or hypercholesterolemic diet(HD) with or without the treatment of these kenaf samples for 32 ***:All the kenaf samples exhibited to contain most of the major *** possessed gallic acid,tannic acid,*** acid,syringic acid,sinapic acid,ferulic acid,naringin acid,and protocatechuic *** significant higher(P<0.05) serum total cholesterol,low density lipoprotein cholesterol and MDA levels in HD group without treatment than the normal control group suggested the hypercholesterolemia was induced by the Incorporation of cholesterol into *** exhibited higher cholesterol-lowering properties due to the significant lower(P<0.05)in serum triglycerides,total cholesterol and MDA *** showed the highest efficiency of cholesterol-lowering activity,followed by *** and ***:*** and KSE appeared lo have comparable anti-hypercholesterolemic effect with the commercial hypocholesterolemic ***,kenaf seed could be used as an alternative natural source lo replace the synthetic hypocholosterolemic drugs.

关键词： Hibiscus cannabinus Hypercholesterolemia Phytochemical screening Phenolic compounds Sprague dawley Oxidative stress

Identification of commonly regulated protein targets and molecular pathways in PC-3 and DU145 androgen-independent human prostate cancer cells treated with the curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2018年第9期8卷 436-445页

作者： Kamini Citalingam Faridah Abas Nordin H.Lajis Iekhsan Othman Rakesh Naidu Jeffery Cheah School of Medicine and Health sciences Monash University Malaysia Jalan Lagoon Selatan Laboratory of Natural Products Faculty of Science Universiti Putra Malaysia department of food science Faculty of Food Science and Technology Universiti Putra Malaysia

Objective: To identify mutually regulated proteins in PC-3 and DU145 androgen-independent prostate cancer cell lines treated with 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one(MS17), and to study the molecular pathways that contributed to the anticancer activity of ***: PC-3 and DU145 cells were treated with 3 × EC_(50)(15 μM) concentration of MS17 for 24 h and were subjected to protein expression profiling using two-dimensional gel electrophoresis and protein identification by mass *** differentially expressed proteins with significant P-value of P<0.05 and fold change over 1.5-folds were filtered through and ontologically *** regulated proteins were ranked by fold change and identified as common protein targets of ***: Profiling data revealed that, the mutually down-regulated proteins included ACTB and ACTG associated with structural molecule activity, ACTN1 with cell cycle, ACTN4 with cell migration, HNRPK with apoptosis, PLST with morphogenesis and TERA with ***, the expressions of CH60 and HS71 A respectively associated with response to unfolded protein demonstrated opposing regulation in PC-3 and DU145 *** analysis of the differentially expressed proteins in PC-3 cells demonstrated the modulation of top pathways associated with cell-cell adhesion and cytoskeletal organization while in DU145 cells the pathways were associated with proteosomal degradation, regulation of electrolytes and water, regulation control of germ cells and organization of filament assembly/***: The findings of the present study provide an understanding on the anti-tumorigenic activity of MS17 at the proteome level and warrant further research for its potential application for the management and treatment of androgen-independent prostate cancer.

关键词： Androgen-independent prostate cancer Diarylpentanoid Proteomics profiling Mass spectrometry Pathway analysis

T4-like coliphage ΦKAZ14 virulent to pathogenic and extended spectrum β-lactamase-producing Escherichia coli of poultry origin

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2015年第1期30卷 73-75页

作者： Kaikabo Adamu Ahmad Abdulkarim Sabo Mohanmmed Faridah Abas Sieo Chin Chin department of food science Faculty of Food Science and Technology Universitiy Putra Malaysia Bacterial Research department National Veterinary Research Institute department of Microbiology Faculty of Biotechnology and Biomolecular Sciences Universitiy Putra Malaysia

Dear Editor,Bacteriophages(otherwise called phages)are a type of virus that infect *** viral type has found useful applications in the control of bacterial pathogens in foods and food processing *** addition,phages ma... 详细信息

关键词： producing pathogenic lactamase ESBL otherwise environments phage chicken poultry avian

Seasonal changes in Porteresia coarctata (Tateoka) beds along a subtropical coast

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Oceanology and Limnology 2013年第1期31卷 1-9页

作者： ABU HENA M K department of Animal science and Fishery Faculty of Agriculture and Food Sciences University Putra Malaysia Bintulu Sarawak Campus

Shoot density, standing crop （above- and below-ground biomass） and habitat of salt marsh grass Porteresia coarctata were investigated along the coast of Bakkhali estuary, Cox＇s Bazar, Bangladesh from January to December 2006. Shoot density of P. coarctata was influenced by season and was found to be higher （〉2 500 shoots/m2） in post-monsoon and minimal in monsoon season; plants were particularly active in vegetative propagation during pre-monsoon. Above-ground biomass was greater along the protected coast compared with the exposed one in this estuary. Below-ground biomass was higher （7.75-269.53 g DW/m2） than that above ground （2.20-114.75 g DW/m2）. Standing crops ofP. coarctata showed a negative relationship （R=-0.77; P〈0.05） with sedimentation rate, while seasonal activity influenced sedimentation. The recorded sedimentation rate was lower （6.09 mg/（cm2·d）） in pre-monsoon and highest （14.55 mg/（cm2·d）） in monsoon season. The mean value of pore water salinity was higher （34.25±65.05） during post-monsoon and lowest （18.0±3.71） in monsoon season. The soil was sandy clay in this P. coarctata bed; it consisted of 86% sand, 13% clay and 1% silt. Soil organic matter dropped during the monsoon season （0.78%-0.67%） and was highest （（2.17±1.42）%-（2.3±1.47）%） during post-monsoon, probably owing to accumulation of decomposed peat on the marsh surface. The mean pore water NH4-N concentration ranged from 2.444-1.65 to 3.33±1.82 μg/L, with a minimum air temperature of 22.09℃ in post-monsoon and a maximum of 31.16℃ in pre-monsoon. Variations of physico-chemical parameters in the soil, water, and climate governed biological parameters of P. coarctata in the Bakkhali estuary, and were comparable with estuarine environments elsewhere.

关键词： standing crop salt marsh Porteresia coarctata Bangladesh

Metabolomics for quality assessment of poultry meat and eggs

在线全文

学校读者我要写书评

暂无评论

food Quality and Safety 2024年第1期8卷 27-40页

作者： M.S.Yogeswari Jinap Selamat Nuzul Noorahya Jambari Alf Khatib Mohd Hishammfariz Mohd Amin Suganya Murugesu Laboratory of food Safety and food Integrity Institute of Tropical Agriculture and Food SecurityUniversiti Putra MalaysiaSerdangSelangor Darul EhsanMalaysia department of food science Faculty of Food Science and TechnologyUniversiti Putra MalaysiaSerdangSelangor Darul EhsanMalaysia department of Pharmaceutical Chemistry Kulliyyah of PharmacyInternational Islamic University MalaysiaKuantanPahang Darul MakmurMalaysia faculty of Pharmacy Airlangga UniversitySurabayaIndonesia department of Veterinary Service malaysia Federal Government Administration CentrePutrajayaMalaysia

The poultry industry is experiencing rapid growth *** accelerated growth has led to multiple food fraud incidents across the food supply chain,which consequently created a demand for precise determination of quality poultry *** increase in demand for precise poultry production quality has necessitated advanced *** has emerged as a viable solution by offering detailed differentiation of biochemical indicators throughout the poultry supply ***,this study provides a means to address risk factors affecting the poultry industry without compromising animal welfare,which is a critical *** review focuses on important issues related to poultry product quality *** adulteration has escalated in recent years as it is driven by the increasing focus on consuming high-quality and nutritious ***,there is no specifc guideline for such determinations,especially when appearance,texture,and taste can be manipulated by substituting for food *** can pave the way for a deeper understanding of existing and novel biochemical indicators responsible for determining the quality of poultry meat and *** approach holds the potential to enhance the overall quality of poultry meat and egg products while also preventing food fraud.

关键词： Poultry metabolomics welfare application authentication.

Roles of fermented plant-,dairy-and meat-based foods in the modulation of allergic responses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

food science and Human Wellness 2023年第3期12卷 691-701页

作者： Muhamad Hafi z Abd Rahim Nur Hazlin Hazrin-Chong Hanis Hazeera Harith Wan Abd Al Qadr Imad Wan-Mohtar Rashidah Sukor faculty of food science and technology Universiti Putra Malaysia43400 SerdangSelangorMalaysia department of Biological sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 BangiSelangorMalaysia faculty of Medicine and Health sciences Universiti Putra Malaysia43400 SerdangSelangorMalaysia Functional Omics and Bioprocess Development Laboratory Institute of Biological SciencesFaculty of ScienceUniversiti Malaya50603 Kuala LumpurMalaysia Laboratory of food Safety and food Integrity Institute of Tropical Agriculture and Food SecurityUniversiti Putra Malaysia43400 SerdangSelangorMalaysia

This review attempts to delineate the effects and roles of fermented foods on allergic responses(AR),specifically from milk,plant,and meat *** for AR alleviation and aggravation were noted for many different fermented food *** outcomes on AR through fermented foods could be linked to microbial hydrolysis of food allergens,improvement in gut microbiota robustness,and modulation of the immune system that promotes a balance between T helper 1(Th1)and Th2 *** on plant-based,non-protein rich fermented foods tend to show more favourable results compared to those on meat-based or protein-rich *** usage of specific and known starter cultures are helpful in alleviating AR,as in the case for many yogurt,Kefir or Dahi *** fermentation time was also deemed important,exemplified in studies that showed inefficient AR reduction through consumption of fresh ***,formation of new allergens through fermentation of certain meat-based foods,or by using specific fermenting microbes(*** sp.),is ***,combination of starter cultures and food substrates must be considered in preventing or eliminating AR from intake of these *** review may aid consumers to make informed decision during the consumption of fermented food.

关键词： Allergy Fermented food Milk-based allergens Plant-based allergens Animal-based allergens

Cloning of a novel phytase from an anaerobic rumen bacterium, Mitsuokella jalaludinii, and its expression in Escherichia coli

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2015年第9期14卷 1816-1826页

作者： TAN Wan-qin Phang Chiun Yee Sieo Chin Chin Yiap Beow Chin Clemente Michael Wong Vui Ling Norhani Abdullah Son Radu Ho Yin Wan Laboratory of Vaccines and Immunotherapeutics Institute of BioscienceUniversiti Putra Malaysia department of Microbiology Faculty of Biotechnology and Biomolecular SciencesUniversiti Putra Malaysia department of Life sciences School of Pharmacy and HealthFaculty of Medicine and HealthInternational Medical University Biotechnology Research Institute Universiti Malaysia Sabah Institute of Tropical Agriculture Universiti Putra Malaysia department of Biochemistry Faculty of Biotechnology and Biomolecular SciencesUniversiti Putra Malaysia department of food science Faculty of Food Science and TechnologyUniversiti Putra Malaysia

The ful length phytase gene of Mitsuokel a jalaludini was successful y cloned and was found to be 1 047 bp in length, with 348 amino acids, and was designated as PHY7 phytase gene. A comparison of the sequence of PHY7 phytase gene of M. jalaludini with various microbial phytase gene sequences showed that it was not similar to those from other bacteria except Selenomonas ruminatium, thus suggesting that they may both express a new class of phytase. The PHY7 phytase gene was subsequently subcloned into bacterial expression vector, pET32a, for expression in Escherichia coli strain Ro-setta-gami. Expression of the recombinant phytase gene was optimised and characterised. The recombinant phytase was estimated to be approximately 55 kDa by SDS-PAGE analysis. The recombinant phytase exhibited optimum activity at 55°C, pH 4.5 and showed good pH stability from pH 3.5 to 5.5 (>78%relative activity). Metal ions such as Ca2+, Mg2+, and K+were found to exert signiifcant stimulatory effect on the recombinant phytase activity while Cu2+, Fe3+, and Zn2+greatly inhibited the enzyme activity. The recombinant phytase showed moderate resistance to trypsin proteolysis, but susceptible to pepsin proteolysis. The results of the study showed that several characteristics of recombinant phytase were slightly different from the native enzyme. Unfavourable characteristics such as reduced pH stability and metal ion effects should be taken into consideration during feed enzyme formulation.

关键词： phytase cloning recombinant Escherichia coli Mitsuokella jalaludinii