检索结果-南通市图书馆

Biomedical and Environmental Sciences 2013年第9期26卷 782-784页

作者： WANG Hai Bin SONG Yan Yan YOU Yuan Hai WANG Heng Wei HAN Qin Hua ZHAO Jian Hong ZHANG Xiao Xi Laboratory of Microbiology Chaoyang District Center for Disease Control and Prevention department of Diagnosis National Institute for Communicable Disease Control and Prevention Chinese Center for DiseaseControl and Prevention State Key Laboratory for Infectious disease Prevention and control

Group A streptococcus （GAS） causes a wide range of diseases in the human population. GAS diseases are more common in children than in adults, with clinical manifestations ranging from pharyngitis and impetigo to invasive infections and post streptococcal sequelae, such as acute rheumatic fever and acute post-streptococcal glomerulonephritis[1]. GAS harbors a host of virulence factors that contribute to its complex pathogenicity and differences in the disease severity and frequency. M protein, one of the major virulence factors, is encoded by the emm gene induces a type of specific host immune response and confers antiphagocytic properties.

关键词： Virulence Factor Genes and Erythromycin Resistant Genes emm Types Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing GAS

Economic Evaluation of the Comprehensive AIDS Prevention and control Program—Tianjin Municipality,China,2011-2022

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China CDC weekly 2023年第48期5卷 1067-1072页

作者： Maohe Yu Jianping Wang Jinhua Zhao Yan Guo Jianyun Bai Zhongquan Liu Hui Gong Tielin Ning Minna Zheng Jinyu Hou Zhuang Cui STD&AIDS control and Prevention Section Tianjin Centers for Disease Control and PreventionTianjinChina Tianjin Key Laboratory of Pathogenic Microbiology of Infectious disease Tianjin Centers for Disease Control and PreventionTianjinChina department of epidemiology and Biostatistics School of Public HealthTianjin Medical UniversityTianjinChina Tianjin Key Laboratory of Environment Nutrition and Public HealthTianjinChina

What is already known about this topic?Acquired immunodeficiency syndrome(AIDS)represents a significant public health challenge globally,not only inflicting harm on the health of individuals but also placing a considerable economic strain on *** is added by this report?This study represents the inaugural report on the potential reduction in economic burden attributable to human immunodeficiency virus(HIV)prevention strategies in *** 2011 and 2022,it is estimated that effective measures could prevent 2,965 new HIV infections and avert 658 deaths,resulting in an economic benefit of approximately 14.437 billion Chinese *** are the implications for public health practice?The findings of this study offer valuable evidence to inform the development of localized HIV prevention and control strategies,as well as to guide public health policymaking.

关键词： prevention globally Tianjin

Evaluation of Latent Tuberculosis Infection Using the ESAT6-CFP10 Skin Test Among International Freshmen With Diverse Skin Tones at a University—Nanjing City,Jiangsu Province,China,September 2023

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China CDC weekly 2024年第35期6卷 896-900,I0001页

作者： Peng Lu Rong Wang Jingjing Xu Jianming Wang Fangfang Du Guozhi Wang Shiming Cheng Limei Zhu department of Chronic Communicable disease Jiangsu Provincial Center for Disease Control and PreventionNanjing CityJiangsu ProvinceChina department of epidemiology School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Nanjing City Center for disease control and Prevention Nanjing CityJiangsu ProvinceChina Chinese Antituberculosis Association BeijingChina National Institutes for Food and Drug control BeijingChina

Introduction:Newer skin tests,including the ESAT6-CFP10(EC)skin test,were recommended for diagnosing Mycobacterium tuberculosis(***)***,no data exist assessing the diagnostic performance of the EC skin test among foreign students with different skin ***:A cohort study at Nanjing Medical University screened incoming foreign *** EC skin test was used to assess for *** infection,and results were read at 24,48,72,and 96-hours ***:Among 96 participants,*** infection rates at 24,48,72,and 96-hours post-injection were 3.13%,7.29%,13.54%,and 9.38%,*** infection rates were lower among individuals with darker skin tones,the difference was not statistically significant(P=0.186),and variations were consistent across different measurement *** analysis revealed 5.3%in the continuousincreasing group,86.5%in the low-stable group,and 5.2%in the elevated-decreasing ***,participants in the elevated-decreasing group had lighter skin tones,with trajectory patterns consistent across different skin ***:The EC skin test is safe,and redness diameter is a more reliable indicator than *** should be collected within 48 to 72 hours,with verification at 72 hours crucial if initial results are ***,skin color does not affect EC skin test outcomes.

关键词： CFP10 Skin Nanjing

Epidemiological Characteristics of Human Rabies——Shandong Province,China,2010-2020

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China CDC weekly 2022年第35期4卷 793-797页

作者： Xiaomei Zhang Xueying Tian Bo Pang Zhiqiang Wang Wenji Zhai Xiaolin Jiang Zengqiang Kou Shujun Ding Xianjun Wang Shandong Provincial Key Laboratory of Communicable disease control and Prevention Department of Communicable Disease Control and PreventionShandong Center for Disease Control and PreventionJinanShandongChina

Introduction:Rabies is a viral zoonotic disease that causes progressive and fatal inflammation in the *** has caused more than 5,000 human deaths in Shandong Province since *** study aimed to analyze the epidemiological characteristics of human rabies in Shandong Province from 2010 to 2020 and to provide a scientific basis for policy ***:The data of reported human rabies cases from 2010 to 2020 were obtained from China’s National Notifiable disease Reporting System,and data related to exposure and post-exposure prophylaxis(PEP)of the cases were acquired through case ***:A total of 414 human rabies cases were reported in Shandong Province from 2010 to *** of the 414 total cases,87.20%were primarily farmers;83.10%were over 40 years old.70.29%(265/377)belonged to categoryⅢexposure;and 96.67%(377/390)were exposed to the virus through infected *** vaccine inoculation rate of these cases after exposure was only 8.85%;1.03%(4/390)had been vaccinated with rabies immunoglobulin,developing the disease 11 to 13 days after categoryⅢ***:Dogs were still the primary animal *** rabies patients died due to no or inadequate post-exposure *** inoculation rates for dogs should reach the target of 70%as soon as *** departments should improve the accessibility and quality of PEP;and improve the health literacy of the elderly in rural areas.

关键词： Shandong category policy

Mapping the high burden areas of cholera in Nepal for potential use of oral cholera vaccine: An analysis of data from publications and routine surveillance systems

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Asian Pacific Journal of Tropical Medicine 2020年第3期13卷 107-114页

作者： Chulwoo Rhee Birendra Prasad Gupta Bibek Kumar Lal Jacqueline Kyungah Lim TAnh Wartel JuliaLynch Sushant Sahastrabuddhe International Vaccine Institute(IVI) SeoulRepublic of Korea epidemiology and disease control Division Department of Health ServicesMinistry of Health and PopulationKathmanduNepal

Objective:To assess the extent of existing published evidence on cholera and to characterize the epidemiologic data of cholera in ***:We conducted a literature scoping review by summarizing published literature reporting on cholera in Nepal from January 1946 to March 2019 in online databases:MEDLINE,Embase,Cochrane,and Global ***,we reviewed national surveillance data on clinically diagnosed and laboratory confirmed cholera reported by the Ministry of Health and ***:Most of the published studies were conducted predominantly in Kathmandu Valley during the rainy season;however,outbreaks have been reported in other parts of Nepal including Terai,Hilly and Mountain *** literature review exhibited that all age groups were affected by cholera,but particularly children and young adults were at-risk age groups in *** cholerae serogroup O1,biotype El Tor,serotype Ogawa has been predominantly isolated with an emergence of resistant strains since *** mass vaccination campaigns using oral cholera vaccines were conducted:Rautahat district in 2014 and Banke district in ***:Capacity building for a nation wide systematic cholera surveillance with rapid and reliable diagnosis is needed to better estimate the burden of cholera and identify geographically at-risk areas associated with the disease in *** is essential for developing an adequate policy on oral cholera vaccine introduction and effective water,sanitation and hygiene interventions.

关键词： Cholera Outbreak Oral cholera vaccine Surveillance Nepal

A Reverse-transcription Recombinase-aided Amplification Assay for the Rapid Detection of the Far-Eastern Subtype of Tick-borne Encephalitis Virus

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Biomedical and Environmental Sciences 2019年第5期32卷 357-362页

作者： WANG Qian Ying LI Fan SHEN Xin Xin FU Shi Hong HE Ying LEI Wen Wen LIANG Guo Dong WANG Huan Yun MA Xue Jun department of Viral Encephalitis NHC Key Laboratory of BiosafetyNational Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China State Key Laboratory for Infectious disease Prevention and control Chinese Center for Disease Control and PreventionBeijing 102206China NHC Key Laboratory of Medical Virology and Viral diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Objective Tick-borne encephalitis virus(TBEV) is an emerging pathogen in Europe and North Asia that causes tick-borne encephalitis(TBE). A simple, rapid method for detecting TBEV RNA is needed to control this disease. Methods A reverse-transcription recombinase-aided amplification(RT-RAA) assay was developed. This assay can be completed in one closed tube at 39℃ within 30 minutes. The sensitivity and specificity of RT-RAA were validated using non-infectious synthetic RNA representing a fragment of the NS5 region of the wild-type(WT) TBEV genome and the Senzhang strain. Additionally, 10 batches of tick samples were used to evaluate the performance of the RT-RAA assay. Results The analytical limit of detection of the assay was 20 copies per reaction of the TBEV synthetic transcript and 3 plaque-forming units(pfu) per reaction of TBEV titers. With the specific assay, no signal due to other arboviruses was observed. Of the 10 batches of tick samples obtained from the Changbai Mountains of China, three were TBEV-positive, which was consistent with the results of the quantitative real-time PCR assay. Conclusion A rapid, highly sensitive, specific, and easy-to-use method was developed for the detection of the TBEV Far-Eastern subtype.

关键词： Tick‐borne encephalitis virus Subtype Far‐eastern Detection RT‐RAA

Acute Effects of Low Temperatures and Cold Waves on Elderly Infectious Pneumonia Mortality—Jinan City,Shandong Province,China,2014-2022

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China CDC weekly 2024年第5期6卷 77-82,I0002-I0005页

作者： Huiyun Chang Mingjun Li Ying Wang Liangliang Cui Tiantian Li Jinan Municipal Center for disease control and Prevention Jinan Municipal Center for Disease Control and Prevention Affiliated to Shandong UniversityJinan CityShandong ProvinceChina Chinese Filed epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?The mortality rate due to pneumonia varies depending on the infectious agents present in a low-temperature *** is added by this report?This study aimed to examine the relationship between low temperatures and cold waves and the risk of mortality from infectious pneumonia in the *** findings indicate a significant increase in the risk of infectious pneumonia.

关键词： environment Shandong finding

Long Distance Transmission of SARS-CoV-2 from Contaminated Cold Chain Products to Humans——Qingdao City,Shandong Province,China,September 2020

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China CDC weekly 2021年第30期3卷 637-644页

作者： Huilai Ma Zhaoguo Wang Xiang Zhao Jun Han Yong Zhang Hong Wang Cao Chen Ji Wang Fachun Jiang Jie Lei Jingdong Song Shaofeng Jiang Shuangli Zhu Huihui Liu Dongyan Wang Yao Meng Naiying Mao Yanhai Wang Zhen Zhu Zhixiao Chen Bingling Wang Qinqin Song Haijun Du Qun Yuan Dong Xia Zhiqiang Xia Peipei Liu Yuchao Wu Zijian Feng Ruqin Gao George F.Gao Wenbo Xu Chinese Field epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina Qingdao Center for disease control and Prevention QingdaoShangdongChina National Institute for Viral disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Shandong Center for disease control and Prevention JinanShandongChina National Institute for Occupational Health and Poison control Chinese Center for Disease Control and PreventionBeijingChina Chinese Center for disease control and Prevention BeijingChina

Summary What is already known about this topic?Though coronavirus disease 2019(COVID-19)has largely been controlled in China,several outbreaks of COVID-19 have occurred from importation of cases or of suspected virus-contaminated *** several outbreaks have been traced to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)isolated on the outer packaging of cold chain products,live virus has not been obtained.

关键词： Chain outer Human

Etiological characteristics of influenza-like illness in Jiangsu province from 2012 to 2016

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The Journal of Biomedical Research 2019年第6期33卷 398-407页

作者： Ke Xu Xiang Huo Rongqiang Zu Shenjiao Wang Yuanfang Qin Qigang Dai Xian Qi Huiyan Yu Lilin Chen Lei Hong Yangting Xu Qianhua Yi Weixiang Wang Xuan Wang Wenjun Dai Jie Zha Weining Han Changjun Bao department of Acute Infectious disease control and Prevention Jiangsu Provincial Center for Disease Control and PreventionNanjingJiangsu 210009China department of Acute Infectious disease control and Prevention Suzhou Municipal Center for Disease Control and PreventionSuzhouJiangsu 215004China department of Acute Infectious disease control and Prevention Nanjing Municipal Center for Disease Control and PreventionNanjingJiangsu 210003China department of Acute Infectious disease control and Prevention Taizhou Municipal Center for Disease Control and PreventionTaizhouJiangsu 225300China

Influenza-like illness(ILI)is an acute respiratory infection caused by various ***,the epidemiologic characteristics of ILI pathogens in Jiangsu province are *** better understand the ILI etiology,the characteristics of the pathogens from nasopharyngeal swab samples of patients with ILI collected from 2012 to 2016 in 6 hospitals in Jiangsu province were *** pathogens,including influenza virus,respiratory syncytial virus(RSV),rhinovirus(HRV),adenovirus(ADV),herpes simplex virus(HSV),human coronavirus(hCoV),Streptococcus pneumoniae and Haemophilus influenzae,were detected by real-time *** least one pathogen was identified in 1334 of the patients(40.23%).Among viruses,HRV,influenza A virus(Flu A),ADV and RSV were the most frequently *** was the only pathogen that was distributed evenly in different years and regions(P>0.05).The etiological distribution varied in different age *** pneumoniae was the most common pathogen in co-infections with a co-detection rate of 64.57%(319/494).The spectrum of etiologies could help to estimate disease burden and provide guidance for vaccination.

关键词： influenza-like illness pathogens co-infection distribution

First Outbreak of Occupational Brucellosis Involving Multiple Clusters--Hubei Province,China,2019

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China CDC weekly 2020年第39期2卷 757-760页

作者： Zhong Zhang Yeqing Tong Xinjun Lei Li Liu Zhiqiang Deng Fei Sun Huilai Ma Zhaorui Chang Lijie Zhang Huihui Liu Qi Chen Jianzhong Zheng Haibing Chen Ximei Sun Yang Wu Xuhua Guan Nanjing Municipal Center for disease control and Prevention NanjingChina Chinese Field epidemiology Training Program(CFETP) BeijingChina Hubei Provincial Center for disease control and Prevention WuhanChina Chongyang Center for disease control and Prevention XianningChina Nanchang Municipal Center for disease control and Prevention NanchangChina Yiling Center for disease control and Prevention YichangChina Division of Infectious disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Xianning Municipal Center for disease control and Prevention XianningChina Jiayu Center for disease control and Prevention XianningChina.

What is already known on this topic?Human brucellosis,a neglected zoonotic disease,causes more than 500,000 new cases each year *** disease is of major public health concern in China,and northern provinces are traditionally endemic *** is added by this report?This is the first published outbreak of occupational brucellosis involving multiple clusters in Hubei *** investigation characterizes the transmission chain of the outbreak and reveals that provinces south of the Yangtze River are faced with a series of challenges and hurdles to overcome including,but not limited to,health education,law enforcement,and occupational *** are the implications for public health practice?In addition to measures aimed at this outbreak,the local agricultural department has issued special notices based on this investigation to adjust and strengthen local eradication program of brucellosis.

关键词： overcome neglected Yangtze