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Data-Driven Healthcare:The Role of Computational Methods in Medical Innovation

Computer Modeling in engineering & Sciences 2025年第1期142卷 1-48页

作者： Hariharasakthisudhan Ponnarengan Sivakumar Rajendran Vikas Khalkar Gunapriya Devarajan Logesh Kamaraj department of Mechanical engineering Dr.Mahalingam College of Engineering and TechnologyPollachiCoimbatoreTamil Nadu642003India department of Mechanical engineering JKKN College of Engineering and TechnologyKumarapalayamNamakkalTamil Nadu637209India department of Mechanical engineering Gharda Institute of TechnologyLavelMaharashtra415708India department of electrical and electronics engineering Sri Eshwar College of EngineeringCoimbatoreTamilnadu641202India department of Mechanical engineering Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and TechnologyChennai600062India

The purpose of this review is to explore the intersection of computational engineering and biomedical science,highlighting the transformative potential this convergence holds for innovation in healthcare and medical *** review covers key topics such as computational modelling,bioinformatics,machine learning in medical diagnostics,and the integration of wearable technology for real-time health *** findings indicate that computational models have significantly enhanced the understanding of complex biological systems,while machine learning algorithms have improved the accuracy of disease prediction and *** synergy between bioinformatics and computational techniques has led to breakthroughs in personalized medicine,enabling more precise treatment ***,the integration of wearable devices with advanced computational methods has opened new avenues for continuous health monitoring and early disease *** review emphasizes the need for interdisciplinary collaboration to further advance this *** research should focus on developing more robust and scalable computational models,enhancing data integration techniques,and addressing ethical considerations related to data privacy and *** fostering innovation at the intersection of these disciplines,the potential to revolutionize healthcare delivery and outcomes becomes increasingly attainable.

关键词： Computational models biomedical engineering bioinformatics machine learning wearable technology

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Wafer‑Scale Ag_(2)S‑Based Memristive Crossbar Arrays with Ultra‑Low Switching‑Energies Reaching Biological Synapses

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Nano-Micro Letters 2025年第3期17卷 328-339页

作者： Yuan Zhu Tomas Nyberg Leif Nyholm Daniel Primetzhofer Xun Shi Zhen Zhang Division of Solid‑State electronics Department of Electrical EngineeringUppsala University75121 UppsalaSweden department of Chemistry Uppsala UniversityUppsalaSweden department of Physics and Astronomy Uppsala UniversityUppsalaSweden State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China

Memristive crossbar arrays(MCAs)offer parallel data storage and processing for energy-efficient neuromorphic ***,most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor(CMOS)technology still suffer from substantially larger energy consumption than biological synapses,due to the slow kinetics of forming conductive paths inside the memristive *** we report wafer-scale Ag_(2)S-based MCAs realized using CMOS-compatible processes at temperatures below 160℃.Ag_(2)S electrolytes supply highly mobile Ag+ions,and provide the Ag/Ag_(2)S interface with low silver nucleation barrier to form silver filaments at low energy *** further enhancing Ag+migration in Ag_(2)S electrolytes via microstructure modulation,the integrated memristors exhibit a record low threshold of approximately−0.1 V,and demonstrate ultra-low switching-energies reaching femtojoule values as observed in biological *** low-temperature process also enables MCA integration on polyimide substrates for applications in flexible ***,the intrinsic nonidealities of the memristive units for deep learning can be compensated by employing an advanced training *** impressive accuracy of 92.6%in image recognition simulations is demonstrated with the MCAs after the *** demonstrated MCAs provide a promising device option for neuromorphic computing with ultra-high energy-efficiency.

关键词： Wafer-scale Ag_(2)S films Reactive sputter Silver nucleation Ag^(+)migration Energy-efficient neuromorphic computing

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Nonlinear optical holograms for spatial and spectral shaping of light waves

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Science Bulletin 2015年第16期60卷 1403-1415页

作者： Asia Shapira Liran Naor Ady Arie department of physical electronics School of Electrical Engineering Tel Aviv University

Shaping either the spatial or the spectral output of a nonlinear interaction is accomplished by introducing basic concepts of computer-generated holography into the nonlinear optics regime. The possibilities of arbitrarily spatially shaping the result of a nonlinear interaction are presented for different phase-matching schemes allowing for both one- and two-dimensional shaping. Shaping the spectrum of a beam in nonlinear interaction is also possible by utilizing similar holographic techniques. The novel and complete control of the output of a nonlinear interaction opens exciting options in the fields of particle manipulation, optical communications, spectroscopy and quantum information.

关键词： Nonlinear optics Beam shaping Spectral shaping Computer-generated holograms

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A comparison study of on-chip short pulse generation circuits based on a coplanar waveguide

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Chinese Physics C 2011年第3期35卷 278-281页

作者：邹焕耿永涛王平山李家胤 department of electrical and Computer engineering Clemson University department of physical electronics University of Electronics Science and Technology of China

A few traditional pulse-forming circuits are implemented in a commercial 0.13 μm digital complementary-metal-oxide-semiconductor （CMOS） technology. These circuits, based on a coplanar waveguide, are analyzed and compared through CadenceTM Spectre simulations. The results show that these traditional pulse-forming-line （PFL） based circuits can be implemented in standard CMOS technology for short pulse generations. Further work is needed to explore the potential of the circuit techniques and to minimize parasitic effects.

关键词： pulse generation circuit transmission line PFL CMOS coplanar waveguide

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Unified MPPT Controller for Partially Shaded Panels in a Photovoltaic Array

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International Journal of Automation and computing 2014年第5期11卷 536-542页

作者： R.Sridhar S.Jeevananthan S.S.Dash N.T.Selvan department of electrical and electronics engineering SRM University department of electrical and electronics engineering Pondicherry Engineering College

The power output of the photovoltaic(PV) system having multiple arrays gets reduced to a great extent when it is partially shaded due to environmental hindrances. The maximum power trackers which are conventionally used may not be competent enough to find the maximum power point(MPP) during partially shaded conditions. The sensible reason for the failure of conventional trackers is during partial shaded conditions the PV arrays exhibit multi peak power curves, thereby making simple maximum power point tracking(MPPT) algorithms like perturb and observe(P&O) to get stuck with local maxima instead of capturing global ***, global search MPPT aided by evolutionary and swarm intelligence algorithms will be conducive to find global power point during partially shaded conditions. This work suggests a unified controller which feeds control signal to its power electronic conditioner placed at each module. The evolutionary algorithm which is taken into consideration in this work is differential evolution(DE).The performance of the proposed method is compared to the classical un-dimensional search controller and it is evident from the Matlab/Simulink results that the unified controller prevails over the distributed counterpart.

关键词： Maximum power point tracking (MPPT) solar energy photovoltaic (PV) differential evolution (DE) solar power generation evolutionary algorithm soft computing

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Tunable diameter electrostatically formed nanowire for high sensitivity gas sensing

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Nano Research 2015年第7期8卷 2206-2215页

作者： Alex Henning Nandhini Swaminathan Andrey Godkin Gil Shalev Iddo Amit Yossi Rosenwaks department of physical electronics School of Electrical Engineering TeI-Aviv University Ramat-Aviv 69978 Israel

We report on an electrostatically formed nanowire （EFN）-based sensor with tunable diameters in the range of 16 nm to 46 nm and demonstrate an EFN- based field-effect transistor as a highly sensitive and robust room temperature gas sensor. The device was carefully designed and fabricated using standard integrated processing to achieve the 16 nm EFN that can be used for sensing without any need for surface modification. The effective diameter for the EFN was determined using Kelvin probe force microscopy accompanied by three- dimensional electrostatic simulations. We show that the EFN transistor is capable of detecting 100 parts per million of ethanol gas with bare SiO2.

关键词： gas sensing,silicon nanowires, Kelvin probe forcemicroscopy (KPFM), electrostatic confinement,multiple gate transistor

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Covering the More Visible Region by Electrochemical Copolymerization of Carbazole and Benzothiadiazole Based Donor-Acceptor Type Monomers

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Chinese Journal of Polymer Science 2019年第1期37卷 28-35页

作者： Emine Gul Cansu-Ergun department of electrical and electronics engineering Baskent University

An electrochromic copolymer film of 2-(3,3-dihexyl-3,4-dihydro-2 H-thieno[3,4-b][1,4]dioxepin-6-yl)-7-(3,3-dihexyl-3,4-dihydro-2 H-thieno[3,4-b][1,4]dioxepin-8-yl)-9 H-carbazole(M1) and 4,7-bis(thiophen-2-yl)benzo[c][1,2,5]thiadiazole(M2) was prepared via electrochemical technique. The copolymerization was performed with one to one monomer feed ratio. Electrochemical and optical properties of the resulting copolymer film(P3) and the homopolymer films of M1 and M2(P1 and P2) were investigated by using cyclic voltammetry and UV-Vis spectrometry techniques, and the corresponding results were compared. Incorporation of M1 and M2 into copolymer matrix was clearly observed on the resulting cyclic voltammograms and UV-Vis spectra. P3 covered the visible regions coming from both P1 and P2, and exhibited a neutral state darker color than those of homopolymers. P3 film was found to have a multichromic behavior, appearing as brown in its neutral state while changing its color upon oxidation to dark-gray(at about 0.3 V), to blue(at about 0.6 V) and finally to grayish cyan(beyond 0.9 V), with a corresponding optical band gap of 1.65 eV.

关键词： Electrochemical polymerization Copolymer Electrochromic polymers

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Analysis of highly efficient perovskite solar cells with inorganic hole transport material

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Chinese Physics B 2019年第12期28卷 393-399页

作者： I Kabir S A Mahmood department of electrical and electronics engineering Bangladesh University of Engineering and Technology

Organo-halide perovskites in planar heterojunction architecture have shown considerable promise as efficient light harvesters in solar cells. We carry out a numerical modeling of a planar lead based perovskite solar cell(PSC) with Cu2ZnSnS4(CZTS) as the hole transporting material(HTM) using the one-dimensional solar cell capacitance simulator(SCAPS-1 D). The effects of numerous parameters such as defect density, thickness, and doping density of the absorber layer on the device performance are investigated. The doping densities and electron affinities of the electron transporting material(ETM) and the HTM are also varied to optimize the PSC performance. It has been observed that a thinner absorber layer of220 nm with a defect density of 1014 cm-3 compared to the reference structure improves the device performance. When doping density of the absorber layer increases beyond 2×1016 cm-3, the power conversion efficiency(PCE) reduces due to enhanced recombination rate. The defect density at the absorber/ETM interface reduces the PCE as well. Considering a series resistance of 5 ?·cm2 and all the optimum parameters of absorber, ETM and HTM layers simultaneously, the overall PCE of the device increases significantly. In comparison with the reference structure, the PCE of the optimized device has been increased from 12.76% to 22.7%, and hence the optimized CZTS based PSC is highly efficient.

关键词： CH3NH3PbI3 Cu2ZnSnS4(CZTS) SCAPS-1D absorption coefficient

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Simulation of Secondary Electron and Backscattered Electron Emission in A6 Relativistic Magnetron Driven by Different Cathode

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Plasma Science and Technology 2015年第1期17卷 64-70页

作者：刘美琴李博轮刘纯亮 Fuks MIKHAIL Edl SCHAMILOGLU Key Laboratory of physical electronics and Devices of the Ministry of Education Xi'an Jiaotong University department of electrical and Computer engineering University of New Mexico

Prticle-in-cell（PIC） simulations demonstrated that,when the relativistic magnetron with diffraction output（MDO） is applied with a 410 kV voltage pulse,or when the relativistic magnetron with radial output is applied with a 350 kV voltage pulse,electrons emitted from the cathode with high energy will strike the anode block *** emitted secondary electrons and backscattered electrons affect the interaction between electrons and RF fields induced by the operating modes,which decreases the output power in the radial output relativistic magnetron by about 15%（10%for the axial output relativistic magnetron）,decreases the anode current by about 5%（5%for the axial output relativistic magnetron）,and leads to a decrease of electronic efficiency by 8%（6%for the axial output relativistic magnetron）.The peak value of the current formed by secondary and backscattered current equals nearly half of the amplitude of the anode current,which may help the growth of parasitic modes when the applied magnetic field is near the critical magnetic field separating neighboring ***,mode competition becomes more serious.

关键词： secondary electron and backscattered electron emission relativistic magnetron mode competition critical magnetic field output power anode current electronic efficiency transparent cathode solid cathode

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RF characteristics of wireless capsule endoscopy in human body

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Journal of Central South University 2016年第5期23卷 1198-1207页

作者：王璟琛王炤 Mark Leach LEE Sanghyuk Eng Gee Lim HUANG Yi department of Electronic and electrical engineering Xi'an Jiaotong-Liverpool University department of electrical engineering and electronics The University of Liverpool

The wireless capsule endoscope,as a small electronic device,has conquered some limitations of traditional wired diagnosing tools,such as the uncomfortableness of the cables for the patient and the inability to examine the very convoluted small intestine ***,this technique is still encountering a lot of practical challenges and is looking for feasible *** work investigates the RF performance of the wireless capsule endoscope system by studying the electromagnetic(EM) wave propagation within the human body.A wireless capsule endoscopy transmission channel model is constructed to serve the purpose of investigating signal attenuations according to the relative position between the transmitter and the *** 300-500 MHz,the S_(21) results are regular and do not display any sudden changes,which allows a suitable expression to be derived for S_(21) in terms of frequency and *** results provide useful information for capsule localization.

关键词： wireless capsule endoscopy (WCE) electromagnetic wave propagation signal attenuations positioning transmission channel

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