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Computer Modeling in Engineering & sciences 2024年第2期138卷 1405-1425页

作者： Muhammad Shoaib Arif Kamaleldin Abodayeh Yasir Nawaz department of Mathematics and sciences College of Humanities and SciencesPrince Sultan UniversityRiyadh11586Saudi Arabia department of Mathematics Air UniversityIslamabad44000Pakistan

This work aimed to construct an epidemic model with fuzzy *** the classical epidemic model doesnot elaborate on the successful interaction of susceptible and infective people,the constructed fuzzy epidemicmodel discusses the more detailed versions of the interactions between infective and susceptible ***-generation matrix approach is employed to find the reproduction number of a deterministic *** analysis and local stability analysis of the systemare also *** solving the fuzzy epidemic model,a numerical scheme is constructed which consists of three time *** numerical scheme has an advantage overthe existing forward Euler scheme for determining the conditions of getting the positive *** establishedscheme also has an advantage over existing non-standard finite difference methods in terms of order of *** stability of the scheme for the considered fuzzy model is also *** the plotted results,it can beobserved that susceptible people decay by rising interaction parameters.

关键词： Epidemic model fuzzy rate parameters next generation matrix local stability proposed numerical scheme

Effects of family non-universal Z′model in angular observables of B→(ρ,a_(1))µ^(+)µ^(−)decays

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Chinese Physics C 2024年第10期48卷 86-113页

作者： Nimra Farooq Marwah Zaki M.Ali Paracha Faisal Munir Bhutta department of Physics School of Natural SciencesNational University of Sciences and TechnologyH-12Islamabad44000Pakistan

We present the angular distribution of the four-fold B→ρ(→ππ)µ^(+)µ^(−) and B→a_(1)(→ρ_(Ⅱ).⊥π)µ^(+)µ^(−) decays in the Standard Model and family non-universal Z'*** the quark level,these decays are govered by the b→dµ^(+)µ^(−) *** with different angular observables,we provide predictions of differential branching ***,forward-backward asymmetry,and longitudinal polarization fractions of ρ and a_(1) *** analysis showsthat the signatures of the fimily non-universal Z’model are more distinct in the observables associated with the B→ρ(→ππ)µ^(+)µ^(−) decay than in those associated with the B→a_(1)(→ρ_(Ⅱ).⊥π)µ^(+)µ^(−) *** measurements ofthe predicted angular observables,both at current and fiuture high energy colliders,will provide useful *** data required to clarify the structure of the family non-universal Z' model in |△b|=△d|=1 processes.

关键词： heavy quark physics B meson physics beyond the Standard Model

Endotoxin-induced alterations of adipose tissue function:a pathway to bovine metabolic stress

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1391-1407页

作者： Miguel Chirivi G.Andres Contreras department of Large Animal Clinical sciences Michigan State UniversityEast LansingMIUSA

During the periparturient period, dairy cows exhibit negative energy balance due to limited appetite and increased energy requirements for lactogenesis. The delicate equilibrium between energy availability and expenditure puts cows in a state of metabolic stress characterized by excessive lipolysis in white adipose tissues(AT), increased production of reactive oxygen species, and immune cell dysfunction. Metabolic stress, especially in AT, increases the risk for metabolic and inflammatory diseases. Around parturition, cows are also susceptible to endotoxemia. Bacterial-derived toxins cause endotoxemia by promoting inflammatory processes and immune cell infiltration in different organs and systems while impacting metabolic function by altering lipolysis, mitochondrial activity, and insulin sensitivity. In dairy cows, endotoxins enter the bloodstream after overcoming the defense mechanisms of the epithelial barriers, particularly during common periparturient conditions such as mastitis, metritis, and pneumonia, or after abrupt changes in the gut microbiome. In the bovine AT, endotoxins induce a pro-inflammatory response and stimulate lipolysis in AT, leading to the release of free fatty acids into the bloodstream. When excessive and protracted, endotoxin-induced lipolysis can impair adipocyte's insulin signaling pathways and lipid synthesis. Endotoxin exposure can also induce oxidative stress in AT through the production of reactive oxygen species by inflammatory cells and other cellular components. This review provides insights into endotoxins' impact on AT function, highlighting the gaps in our knowledge of the mechanisms underlying AT dysfunction, its connection with periparturient cows' disease risk, and the need to develop effective interventions to prevent and treat endotoxemia-related inflammatory conditions in dairy cattle.

关键词： Adipose tissue dysfunction Endotoxin Inflammation Insulin resistance

Optimised CNN Architectures for Handwritten Arabic Character Recognition

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Computers, Materials & Continua 2024年第6期79卷 4905-4924页

作者： Salah Alghyaline department of Computer Science TheWorld Islamic Sciences and Education UniversityAmman1101-11947Jordan

Handwritten character recognition is considered challenging compared with machine-printed characters due to the different human writing *** is morphologically rich,and its characters have a high *** Arabic language includes 28 *** character has up to four shapes according to its location in the word(at the beginning,middle,end,and isolated).This paper proposed 12 CNN architectures for recognizing handwritten Arabic *** proposed architectures were derived from the popular CNN architectures,such as VGG,ResNet,and Inception,to make them applicable to recognizing character-size *** experimental results on three well-known datasets showed that the proposed architectures significantly enhanced the recognition rate compared to the baseline *** experiments showed that data augmentation improved the models’accuracies on all tested *** proposed model outperformed most of the existing *** best achieved results were 93.05%,98.30%,and 96.88%on the HIJJA,AHCD,and AIA9K datasets.

关键词： Optical character recognition(OCR) handwritten arabic characters deep learning

Adverse effects of early-life stress:focus on the rodent neuroendocrine system

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Neural Regeneration Research 2024年第2期19卷 336-341页

作者： Seung Hyun Lee Eui-Man Jung department of Molecular Biology College of Natural SciencesPusan National UniversityBusanRepublic of Korea

Early-life stress is associated with a high prevalence of mental illnesses such as post-traumatic stress disorders,attention-deficit/hyperactivity disorder,schizophrenia,and anxiety or depressive behavior,which constitute major public health *** the early stages of brain development after birth,events such as synaptogenesis,neuron maturation,and glial differentiation occur in a highly orchestrated manner,and external stress can cause adverse long-term effects throughout *** body utilizes multifaceted mechanisms,including neuroendocrine and neurotransmitter signaling pathways,to appropriately process external *** individuals first exposed to early-life stress deploy neurogenesis as a stress-defense mechanism;however,in adulthood,early-life stress induces apoptosis of mature neurons,activation of immune responses,and reduction of neurotrophic factors,leading to anxiety,depression,and cognitive and memory *** process involves the hypothalamus-pituitary-adrenal axis and neurotransmitters secreted by the central nervous system,including norepinephrine,dopamine,and *** rodent early-life stress model is generally used to experimentally assess the effects of stress during *** paper reviews the use of the early-life stress model and stress response mechanisms of the body and discusses the experimental results regarding how early-life stress mediates stress-related pathways at a high vulnerability of psychiatric disorder in adulthood.

关键词： early-life stress hypothalamic-pituitary-adrenergic axis maternal separation mental illness neurodevelopmental disorder neuroendocrine system neurotransmitter

Feeding prehistoric coastal community:A study of marine faunal remains at the Jingtoushan site

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Science China Earth sciences 2024年第5期67卷 1574-1590页

作者： Endong WU Guoping SUN Ying ZHANG School of Culture History and LanguageAustralian National UniversityCanberra 2600Australia Zhejiang Provincial Institute of cultural Relics and Archaeology Hangzhou 310012China National Centre for Archaeology Beijing 100013China

This article examines the abundant marine mollusc,and fish remains at the Jingtoushan shell midden(8,300 to7,800 cal a BP)in Zhejiang Province,China,to investigate the fishing economy,community development,the palaeoenvironment,and their interactions among the prehistoric populations in the lower Yangtze River Basin and southeastern coastal *** also attempts to explore the prosperity and decline of coastal settlements in China during the Neolithic Age and the potential reasons for their rise and fall,*** on the ecological and biological principles of marine animals,standard zooarchaeological methods and radiocarbon dating analysis are used for sampling,identification,measurement,and *** show that at least 11 mollusc taxa and 14 fish taxa can be identified from the Jingtoushan faunal *** ancient Jingtoushan residents possibly lived in a settlement close to the coast and engaged in inshore and offshore fishing,hunting,and gathering as their primary subsistence strategies,with low-level rice cultivation as a supplementary means of ***,the changes in the coastal environment could be one of the reasons why the Jingtoushan residents abandoned their *** research contributes to Chinese Neolithic archaeology with new evidence of the exploitation of marine resources around 8000 a BP in the eastern coastal areas and the relationship between Neolithic community development and environmental changes.

关键词： Neolithic Age Marine faunal remains Fishing economy Palaeoenvironment Community development

Unsteady MHD Casson Nanofluid Flow Past an Exponentially Accelerated Vertical Plate:An Analytical Strategy

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Computer Modeling in Engineering & sciences 2024年第7期140卷 431-460页

作者： T.Aghalya R.Tamizharasi department of Mathematics School of Advanced SciencesVellore Institute of TechnologyVelloreTamilnadu632014India

In this study,the characteristics of heat transfer on an unsteady magnetohydrodynamic(MHD)Casson nanofluid over an exponentially accelerated vertical porous plate with rotating effects were *** flow was driven by the combined effects of the magnetic field,heat radiation,heat source/sink and chemical *** oxide(CuO)and titanium oxide(TiO2)are acknowledged as nanoparticle *** nondimensional governing equations were subjected to the Laplace transformation technique to derive closed-form *** representations are provided to analyze how changes in physical parameters,such as the magnetic field,heat radiation,heat source/sink and chemical reaction,affect the velocity,temperature and concentration *** computed values of skin friction,heat and mass transfer rates at the surface were tabulated for various sets of input *** is perceived that there is a drop in temperature due to the rise in the heat source/sink and the Prandtl *** should be noted that a boost in the thermal radiation parameter prompts an increase in *** increase in the Prandtl number,heat source/sink parameter,time and a decrease in the thermal radiation parameter result in an increase in theNusselt *** computed values of the skin friction,heat andmass transfer rates at the surface were tabulated for various values of the flow *** present results were compared with those of previously published studies andwere found to be in excellent *** research has practical applications in areas such as drug delivery,thermal medicine and cancer treatment.

关键词： Thermal radiation radiative flux nanofluid copper oxide titanium oxide accelerated plate

Single-cell RNA sequencing to understand host-virus interactions

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Virologica Sinica 2024年第1期39卷 1-8页

作者： Jia-Tong Chang Li-Bo Liu Pei-Gang Wang Jing An department of Microbiology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China

Single-cell RNA sequencing(scRNA-seq)has allowed for the profiling of host and virus transcripts and host-virus interactions at single-cell *** review summarizes the existing scRNA-seq technologies together with their strengths and *** applications of scRNA-seq in various virological studies are discussed in depth,which broaden the understanding of the immune atlas,host-virus interactions,and immune ***-seq can be widely used for virology in the near future to better understand the pathogenic mechanisms and discover more effective therapeutic strategies.

关键词： Single-cell RNA sequencing(scRNA-seq) Host-virus interaction COVID-19 Flavivirus

On hypersurfaces of H2×H2

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Science China Mathematics 2024年第2期67卷 339-366页

作者： Dong Gao Hui Ma Zeke Yao School of Science Beijing University of Civil Engineering and Architecture department of Mathematical sciences Tsinghua University

In this paper, we study hypersurfaces of H2× H2. We first classify the hypersurfaces with constant principal curvatures and constant product angle functions. Then we classify homogeneous hypersurfaces and isoparametric hypersurfaces, respectively. Finally, we classify the hypersurfaces with at most two distinct constant principal curvatures, as well as those with three distinct constant principal curvatures under some additional conditions.

关键词： constant principal curvature homogeneous hypersurface isoparametric hypersurface 53C42 53B25 53C40

Mineral Chemistry,Trace Elements,Isotopic Analysis and Zircon U-Pb Dating in the Hesar Pluton,Northern UDMA,Iran:Implications for Pre-Collisional Magma Mixing

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 657-678页

作者： Kazem KAZEMI Soroush MODABBERI Parisa GHARIBNEJAD XIAO Yilin Fatemeh SARJOUGHIAN Ali KANANIAN School of Geology College of ScienceUniversity of TehranTehranIran Research Centre for Mineral Resources Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China National Key Laboratory of Ecological Security and Resource Utilization in Arid Areas Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China department of Geochemistry and Environmental sciences School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China department of Earth and sciences Faculty of SciencesUniversity of KurdistanSanandajIran department of Science Education Farhangian UniversityTehranIran

The Hesar pluton in the northern Urumieh-Dokhtar magmatic arc hosts numerous mafic-microgranular enclaves(MMEs).Whole rock geochemistry,mineral chemistry,zircon U-Pb and Sr-Nd isotopes were *** is suggested that the rocks are metaluminous(A/CNK=1.32-1.45),subduction-related I-type calc-alkaline gabbro to diorite with similar mineral assemblages and geochemical *** host rocks yielded an U-Pb crystallization age of 37.3±0.4 Ma for *** have relatively low SiO_(2) contents(52.9-56.6 wt%)and high Mg^(#)(49.8-58.7),probably reflecting a mantle-derived ***-and mantle-normalized trace element patterns are characterized by LREE and LILE enrichment,HREE and HFSE depletion with slight negative Eu anomalies(Eu/Eu^(*)=0.86-1.03).The host rocks yield(^(87)Sr/^(86)Sr)_(i) ratios of 0.70492-0.70510,positive ε_(Nd)(t)values of+1.55-+2.06 and T_(DM2)of 707-736 Ma,which is consistent with the associated mafic microgranular enclaves((^(87)Sr/^(86)Sr)_(i)=0.705014,ε_(Nd)(t)=+1.75,T_(DM2)=729 Ma).All data suggest magma-mixing for enclave and host rock formation,showing a complete equilibration between mixed-mafic and felsic magmas,followed by rapid *** T_(DM1)(Nd)and T_(DM2)(Nd)model ages and U-Pb dating indicate that the host pluton was produced by partial melting of the lower continental crust and subsequent mixing with injected lithospheric mantlederived magmas in a pre-collisional setting of Arabian-Eurasian *** composition indicates a crystallization temperature of~1000℃ and a depth of~9 km.

关键词： enclave magma mixing zircon U-Pb dating Urumieh-Dokhtar magmatic arc