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Present status and future directions:Apexification

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World Journal of Methodology 2025年第1期15卷 26-32页

作者： Sachin Chauhan Radha Chauhan Prashant Bhasin Bhavna G Sharaf department of Conservative Dentistry and Endodontics Sudha Rustagi College of Dental Sciences and ResearchFaridabad 121002HaryanaIndia department of prosthodontics and crown and bridge and Oral Implantology Mahatma Gandhi Dental College&HospitalJaipur 302022RajasthanIndia department of Pedodontics and Preventive Dentistry Sudha Rustagi College of Dental Sciences and ResearchFaridabad 121002HaryanaIndia

The success rate of apexification is primarily determined by multiple factors,including the material used,the size of the open apex compared to the length of the root,and the technique used in each *** main objective of this review was to provide an update on the present management of open apex to identify factors and circumstances that may influence the success of apexification using different materials and *** research on apexification should focus on how to treat open apices with wide periapical lesions without ***,the predictability of these parameters with non-surgical procedures was uncertain,but now,with the use of a dental operating microscope,it has become more *** reason could be that extra visits are no longer required due to major advances in the armamentarium and materials used for apexification.

关键词： Bioceramics Magnification Biodentine Mineral trioxide aggregate Apexification Open apex

Effect of Self-adhesive Resin Cement and Tribochemical Treatment on Bond Strength to Zirconia

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International Journal of Oral Science 2010年第1期2卷 28-34页

作者： Akikazu Shinya Harunori Gomi Akiyoshi Shinya department of crown and bridge School of Life Dentistry at TokyoThe Nippon Dental University

Aim To evaluate the interactive effects of different self- adhesive resin cements and tribochemical treatment on bond strength to zirconia. Methodology The following self-adhesive resin cements for bonding two zirconia blocks were evaluated： Maxcem （MA）, Smartcem （SM）, Rely X Unicem Aplicap （UN）, Breeze （BR）, Biscem （BI）, Set （SE）, and Clearfil SA luting （CL）. The specimens were grouped according to conditioning as follows： Group 1, polishing with 600 grit polishing paper; Group 2, silica coating with 110 μm Al2O3 particles which modified with silica; and, Group 3, tribochemical treatment - silica coating ＋ silanization. Specimens were stored in distilled water at 37℃ for 24 hours before testing shear bond strength. Results Silica coating and tribochemical treatment significantly increased the bond strength of the MA, UN, BR, B1, SE and CL to zirconia compared to #600 polishing. For both #600 polished and silica coating treatments, MDP- containing self-adhesive resin cement CL had the highest bond strengths to zirconia. Conclusion Applying silica coating and tribochemical treatment improved the bond strength of self-adhesive resin cement to zirconia, especially for CL.

关键词： self-adhesive resin cement zirconia silica coating tribochemical treatment bond strength

Non-Thermal Atmospheric Plasma:Can it Be Taken as a Common Solution for the Surface Treatment of Dental Materials?

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Plasma Science and Technology 2016年第4期18卷 417-423页

作者： Emre SEKER Mehmet Ali KILICARSLAN Serdar POLAT Emre OZKIR Suat PAT department of prosthodontics Faculty of DentistryEskisehir Osmangazi University department of prosthodontics Faculty of DentistryAnkara University department of prosthodontics Faculty of DentistryGazi University department of prosthodontics Faculty of DentistryAfyon Kocatepe University Faculty of Art and Science Eskisehir Osmangazi University

This study aimed to evaluate the surface roughness and wetting properties of various dental prosthetic materials after different durations of non-thermal atmospheric plasma（NTAP）*** hundred and sixty discs of titanium（Ti）（n：40）,cobalt chromium（Co-Cr）（n：40）,yttrium stabilized tetragonal zirconia polycrystals（Y-TZP）（n：40）and polymethylmethacrylate（PMMA）（n：40）materials were machined and smoothed with silicon carbide *** surface roughness was evaluated in a control group and in groups with different plasma exposure times [1-3-5 s].The average surface roughness（Ra）and contact angle（CA）measurements were recorded via an atomic force microscope（AFM）and tensiometer,*** changes were examined with a scanning electron microscope（SEM）.Data were analyzed with two-way analysis of variance（ANOVA）and the Tukey HSD test α=0.05）.According to the results,the NTAP surface treatment significantly affected the roughness and wettability properties（P 〈 0.05）.SEM images reveal that more grooves were present in the NTAP *** an increase in the NTAP application time,an apparent increment was observed for Ra,except in the PMMA group,and a remarkable reduction in CA was observed in all *** is concluded that the NTAP technology could enhance the roughening and wetting performance of various dental materials.

关键词： dental material atmospheric plasma surface treatment roughness contact angle

Revolutionizing breast cancer detection:Advances in fluorescent probe technology

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Nano Research 2025年第1期18卷 653-674页

作者： Qian Gao Lin Tang Jun Zhan Yiyuan Xue Feng Luo State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu 610041China Emergency Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China department of prosthodontics West China School of StomatologySichuan UniversityChengdu 610041China

With the increasing incidence of breast cancer globally,there is an urgent demand for enhanced diagnostic and therapeutic *** comprehensive review explores advancements in fluorescent probe technology for breast cancer imaging and early *** probes offer unparalleled sensitivity and specificity in detecting cancer biomarkers,enabling early diagnosis and delineation of tumor margins during *** categorize these probes into molecular,nano,ratiometric,the second near-infrared window(NIR-II),and multifunctional varieties,each with unique capabilities for targeting specific cancer *** review highlights recent innovations in probe design,emphasizing their applications in pathogenesis studies,drug development,precision medicine,and fluorescence-guided *** their promising clinical potential,challenges such as safety,biomarker targeting accuracy,system compatibility,and clinical translation *** these hurdles is crucial for the integration of fluorescent probes into standard cancer care,aiming to improve treatment outcomes and patient quality of life.

关键词： breast cancer fluorescent probes imaging early diagnosis biomarker

Effect of Different Pretreatments to Post-space on Bonding Strength of Fiber Posts Luted with a Self-adhesive Resin Cement

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Journal of Wuhan University of Technology(Materials Science) 2013年第5期28卷 984-989页

作者：夏勇程祥荣 department of prosthodontics School and Hospital of StomatologyWuhan University

The effects of different post-space pretreatments on the retentive force of fiber posts cemented with a self-adhesive resin cement were investigated. Twenty-eight single-canal premolars were obturated by Resilon using warm vertical compaction and treated with distilled water, 2.5% NaOCl, 17% EDTA and 2.5% NaOCI; or 17% EDTA, 2.5% NaOCI, and ultrasonic agitation （U/E/N treatment）. Subsequently, radicular dentin surfaces were observed under scanning electron microscopy （SEM）. RelyX Fiber Posts were cemented in the treated canals by using RelyX U100, and thin-slice push-out test and SEM observation of coronal and apical regions of the specimens were performed. Data were analyzed using two-way ANOVA and Tukey＇s HSD post- hoc tests, and the percentage of failure type was calculated. Ultrasonic/EDTA/NaOC1 irrigation showed the maximum effectiveness in removing the smear layer and debris on the dentin surface. The apical bond strength of the experimental groups was significantly higher than that of the control group （P〈 0.05）. Adhesive failure between cement and dentin was the most common mode of failure. No obvious RDIZ or resin tag was detected. Chemical irrigants facilitated the bonding of these fiber posts, and ultrasonic activation improved retention. Future studies should evaluate the effectiveness of irrigation on fiber post push-out strength in fatigue cycling condition.

关键词： irrigation post space push-out strength Resilon self-adhesive cements smear layer

Influence of acrylamide monomer addition to the acrylic denture-base resins on mechanical and physical properties

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International Journal of Oral Science 2013年第4期5卷 229-235页

作者： Elif Aydogan Ayaz Rukiye Durkan department of prosthodontics Faculty of DentistryKaradeniz Technical University

The aim of the study was to evaluate the effect of adding acrylamide monomer （AAm） on the characterization, flexural strength, flexural modulus and thermal degradation temperature of poly（methyl methacrylate）（PMMA） denture-base resins. Specimens （n= 10） were fabricated from a conventional heat-activated QC-20 （Qc-） and a microwave heat-activated Acron MC （Ac-） PMMA resins. Powder/ liquid ratio followed the manufacturer＇s instructions for the control groups （Qc-c and Ac-c） and for the copolymer groups, the resins were prepared with 5% （-5）, 10% （- 10）, 15% （- 15） and 20% （-20） acrylamide contents, according to the molecular weight ratio, respectively. The flexural strength and flexural modulus were measured by a three-point bending test. The data obtained were statistically analyzed by Kruskal-Wallis test （a=O.05） to determine significant differences between the groups, The chemical structures of the resins were characterized by the nuclear magnetic resonance spectroscopy. Thermal stabilities were determined by thermogravimetric analysis （TGA） with a heating rate of 10 ~***-1 from 35 ~C to 600 ~C. Control groups from both acrylic resins showed the lowest flexural strength values. Qc-15 showed significant increase in the flexural strength when compared to Qc-c （P〈O.01）. Ac-10 and Ac-15 showed significance when compared to Ac-c （P〈O.01）. Acrylamide incorporation increased the elastic modulus in Qc-10, Qc-15 and Qc-20 when compared to Qc-c （P〈0.01）. Also significant increase was observed in Ac-10, Ac-15 and Ac-20 copolymer groups when compared to Ac-c （P〈0.01）. According to the 1H-nuclear magnetic resonance （NMR） results, acrylamide copolymerization was confirmed in the experimental groups. TGA results showed that the thermal stability of PMMA is increased by the insertion of AAm.

关键词： acrylamide denture resin nuclear magnetic resonance poly(methyl methacrylate) thermogravimetric analysis three-point bending test

Study on repairing canine mandibular defect with porous Mg-Sr alloy combined with Mg-Sr alloy membrane

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Regenerative Biomaterials 2020年第3期7卷 331-336页

作者： Shanning Zhang Xirao Sun Chunyu Kang Man Yang Yuan Zhao Chengyue Wang department of prosthodontics Second Affiliated Hospital of Jinzhou Medical UniversityJinzhou 121000China department of prosthodontics JinZhouShi Oral Cavity HospitalJinzhou 121000China

To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in *** second and third mandibular premolars on both sides were extracted from six *** model of mandible buccal fenestration bone defects were prepared after the sockets *** bone defects were randomly divided into groups A and B,then Mg-Sr alloy was implanted in bone defects of group A and covered by Mg-Sr alloy membrane while Mg-Sr alloy was implanted in bone defects of group B and covered by mineralized collagen *** defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4,8 and 12 *** 12 weeks,the healing of bone defects were evaluated by gross observation,X-ray microscopes and histological observation of hard *** defects in each group were *** 8 and 12 weeks,the gray value of group A was higher than that of group B(P<0.05).At 12 weeks,the bone volume fraction of group A was higher than that of group B(P<0.05).The newly woven bone in group A is thick and arranged staggered,which was better than that of group *** Mg-Sr alloy combined with Mg-Sr alloy membrane could further promote the repair of mandibular defects,and obtain good osteogenic effect.

关键词： Mg-Sr alloy Mg-Sr alloy membrane mineralized collagen membrane mandibular defects guided bone regeneration

Tooth wear against ceramic crowns in posterior region: a systematic literature review

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International Journal of Oral Science 2013年第4期5卷 183-190页

作者： Rim Hmaidouch Paul Weigl department of prosthodontics and Geriatric Dentistry Johann Wolfgang Goethe University

The objective of this systematic review was to assess tooth wear against ceramic crowns in posterior region in vitro and in vivo. An electronic PubMed search was conducted to identify studies on tooth wear against ceramic crowns in posterior region. The selected studies were analyzed in regard to type of crowns, natural antagonist, measuring protocol and outcome. From a yield of 1 000 titles, 43 articles were selected for full-text analysis; finally, no in vitro and only five in vivo studies met the inclusion criteria. As there is heterogeneity in design, used measuring method, ceramics and analysis-form, a meta-analysis was not possible. Results of these studies are very controversial which makes a scientifically valid comparison impossible. This review indicated that some all-ceramic crowns are as wear friendly as metal-ceramic crowns. Up to now, it has been impossible to associate tooth wear with any specific causal agent. The role of ceramic surface treatment that might be responsible for the changing in rate of tooth wear seems undetermined as yet through clinical trials. The literature reveals that studies on this topic are subject to a substantial amount of bias. Therefore, additional clinical studies, properly designed to diminish bias, are warranted.

关键词： all-ceramic crowns tooth wear

New Mini Dental Implant Attachments versus O-ring Attachment after Cyclic Aging: Analysis of Retention Strength and Gap Space

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2017年第3期37卷 419-424页

作者： Abdalbseet A Fatalla 宋珂曹颖光 department of prosthodontics and Implantology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology department of prosthodontics College of Dentistry University of Baghdad

Overdenture as a treatment modality for both partially and fully edentulous patients is costeffective and less expensive. The purpose of the present study was to examine the newly fabricated attachments by comparing them with conventional O-ring attachment in vitro in terms of retention force and cyclic aging resistance. A total of 150 samples were prepared and divided into five groups according to the materials used(O-ring attachment, Deflex M10 XR, Deflex Classic SR, Deflex Acrilato FD, and flexible acrylic resin). The retention force of different attachments was measured by a mini dental implant after three subsequent aging(0, 63, and 126) cycles in the circumstances similar to the oral environment. The gap space between the head of the implant and the inner surface of the attachments was detected. Two-way analysis of variance(ANOVA) analysis with multiple comparisons test was applied for statistical analysis. The results showed that Deflex M10 XR had the highest retention force and the lowest gap space after cyclic aging; in addition, by comparing the relative force reduction, the lowest values were obtained in the O-ring attachment and the highest values in the flexible acrylic resin attachment. The retention force measured after cyclic aging for the Deflex M10 XR attachment was greatly improved when compared with the O-ring attachment and other types of attachment materials; in addition, the Deflex M10 XR attachment exhibited the minimum gap space between the inner surface and the mini dental implant head. In conclusion, Deflex M10 XR has the ability to withstand weathering conditions and retains its durable and retentive properties after aging when compared with other attachments.

关键词： mini dental implant O-ring attachment flexible acrylic resin deflex material