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肺栓塞的诊断:妇科肿瘤学中螺旋CT肺动脉造影术的应用经验

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世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 42-43页

作者： Martino M.A. Williamson E. Siegfried S. 刘亦恒 department of Obstetrics and Gynecology University of South Florida Harbourside Medical Towers 4 Columbia Drive Tampa FL 33606 United States

Objectives. To review our experience with the diagnosis and prognosis of pulmonary embolism (PE) in gynecologic oncology patients. Methods. Spiral CT pulmonary angiography (CTPA) studies on gynecologic oncology patients were collected from our radiology database from 6/2001 to 6/2003. Patient charts were retrospectively reviewed. Data were abstracted relative to presenting symptoms, demographics and laboratory and diagnostic evaluations. Patient data were compared using chi-square contingency tables and logistic regression analysis. Survival was studied using the Kaplan-Meier method and the log rank test. The effect of PE on survival was adjusted using a proportional hazards regression model. Results. One-hundred and eleven CTPA studies were performed over 2 years and 25 patients were diagnosed with *** PE (n = 25) and non-PE (n = 86) groups were similar for age, race, BMI and cancer diagnosis. Tachycardia (P = 0.02, OR = 3.03 95% CI 1.16-7.94 ) and leukocytosis (P = 0.04, OR = 2.93 95% CI 1.05-8.18 ) were more frequent among PE patients and confirmed as independently prognostic of *** other clinical and laboratory findings were similar between patients with and without PE. Overall survival for patients with and without PE was 63% versus 94% , respectively, at 2 years (P = 0.02). Conclusion. In a gynecologic oncology patient with high clinical suspicion for PE, our clinical pre-test probability was 23.0% . Two-year mortality rates were 6-fold higher for patients diagnosed with PE. The significant overlap in clinical presentations, multiple risk factors and higher mortality rates encourage the aggressive diagnosis and treatment of PE among this population. Further work is needed to reduce the incidence and mortality rate of PE.

关键词：妇科肿瘤学动脉造影术肺栓塞妇科肿瘤患者癌症诊断存活者列联表诊断评价模型校正年死亡率

髓腔内压对树脂水门汀与牙本质粘接强度的影响

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北京大学学报（医学版） 2019年第2期51卷 321-326页

作者：潘怡湘李秀花田福聪王晓燕北京大学口腔医学院.口腔医院牙体牙髓科国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院.口腔医院第五门诊部北京100020 department of Endodontics Dental College of GeorgiaAugusta University

目的:评价髓腔内压条件对树脂水门汀与牙本质微拉伸粘接强度的影响。方法:选择新拔除的人无龋第三磨牙30颗分成2组,去除咬合面釉质制备牙本质平面,选取剩余牙本质厚度为0.5~2.5 mm的牙本质试样,在有染料的髓腔内压条件下,观察牙本质表... 详细信息

目的:评价髓腔内压条件对树脂水门汀与牙本质微拉伸粘接强度的影响。方法:选择新拔除的人无龋第三磨牙30颗分成2组,去除咬合面釉质制备牙本质平面,选取剩余牙本质厚度为0.5~2.5 mm的牙本质试样,在有染料的髓腔内压条件下,观察牙本质表面与牙面处理剂Single Bond Universal(SBU)固化后表面在即刻、5 min、30min、2 h的染料渗透情况。保持最小剩余牙本质厚度为(1.0±0.1)mm,分别在有或无髓腔内压条件(15或0cm H2O,1 cm H2O=0.098 k Pa)下维持30 min,使用SBU并光照固化,然后使用模具在牙本质表面堆塑Rely X Ultimate(RLX)树脂水门汀(直径10 mm,高4 mm),制备牙本质-树脂水门汀粘接试样。试样在37℃蒸馏水中储存24 h后,将牙本质-树脂水门汀试样垂直于粘接界面切割形成横截面积为0.9 mm×0.9 mm条状试样,使用微拉伸测试仪测试计算其粘接强度(两独立样本t检验,双侧检验水平α=0.05),用扫描电镜观察统计试样断裂类型(Fisher精确检验,双侧检验水平α=0.05)。将牙本质-树脂水门汀试样垂直粘接界面做切片,厚度0.8 mm,扫描电镜下观察粘接界面形貌。结果:在髓腔内压条件下,随时间延长,粘接表面染料渗出增加。有髓腔内压时和无髓腔内压时RLX与牙本质微拉伸粘接强度分别为:(26.26±9.78)MPa和(28.70±9.09)MPa,两者差异无统计学意义(P>0.05)。两组试样断裂类型无明显差异(P>0.05),都以混合断裂为主。两组试样粘接界面可见4~8μm指状树脂突,分布及长短较均匀,形貌无明显差异。结论:SBU预处理牙本质后,髓腔内压不影响树脂水门汀RLX的即刻牙本质粘接强度。

关键词：树脂水门汀髓腔内压牙本质拉伸强度

玻璃体和通用型复合树脂耐磨性的临床对照研究

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北京大学学报（医学版） 2021年第1期53卷 120-125页

作者：穆海丽田福聪王晓燕高学军北京大学口腔医学院·口腔医院牙体牙髓科国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院·口腔医院第一门诊部综合科北京100034 department of Endodontics Dental College of Georgia Augusta University Augusta 300912 USA

目的:采用激光三维扫描技术评估玻璃体和通用型复合树脂用于后牙充填的耐磨性。方法:根据纳入标准选取48名患者共108颗患牙(每组各54颗),随机分配用玻璃体(BeautifilⅡ,简称BF)或通用型复合树脂(Filtek Z350,简称Z350)进行充填。分别于... 详细信息

目的:采用激光三维扫描技术评估玻璃体和通用型复合树脂用于后牙充填的耐磨性。方法:根据纳入标准选取48名患者共108颗患牙(每组各54颗),随机分配用玻璃体(BeautifilⅡ,简称BF)或通用型复合树脂(Filtek Z350,简称Z350)进行充填。分别于术后1周、6个月、18个月和4年,采用改良美国公共卫生署(United States Public Health Service,USPHS)标准对充填体进行临床评价并拍照和制取模型。使用激光三维扫描仪扫描模型后,对图像进行配准和计算磨耗深度,使用SPSS 20.0进行统计分析。结果:术后4年回访43名患者,回访率为89.6%。BF组和Z350组各有4例和3例出现脱落、继发龋、充填体折断和牙髓坏死。两组充填体的4年存留率均为95.8%,符合美国牙医协会(American Dental Association,ADA)标准(3年存留率>90%)。0~6个月两组充填体的磨耗速率最快,随后磨耗速率的下降趋于平缓,BF组4年总磨耗深度为(58±22)μm,Z350组为(54±16)μm(P>0.05),耐磨性均符合ADA标准(3年磨耗深度0.05)。结论:玻璃体的4年存留率和耐磨性均符合ADA标准,用于后牙牙合面重咬合接触区时,玻璃体的耐磨性略逊于复合树脂,用于非重咬合接触区时,二者间无明显差异。

关键词：复合树脂类牙修复磨损成像,三维

炎症性肠病患儿血清学标志物诊断的准确性:西弗吉尼亚的一项经验

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世界核心医学期刊文摘（胃肠病学分册） 2005年第12期1卷 43-43页

作者： Elitsur Y. Lawrence Z. Tolaymat N. 赵菊辉 department of Pediatrics Marshall University Joan C. Edwards School of Medicine 1600 Medical Center Drive Huntington WV 25701 United States Dr.

Goal: To assess the sensitivity/specificity of the serologic markers: perinuclear antineutrophil cytoplasmic antibody (pANCA) and anti- saccharomyces cerevisiae antibody (ASCA) in children diagnosed with inflammatory bowel disease (IBD), living in West Virginia. Background: In recent years, serologic markers have been used to differentiate between CD and UC diseases in children. The clinical usefulness of these markers in children was restricted by their low sensitivity and specificity. Racial and ethnic diversity may alter the accuracy of these markers in children. The demographic homogeneity of the West Virginia population may offer a better clinical setup to reassess the utility of those markers in children with IBD. Study: A retrospective analysis of all the charts of children diagnosed with IBD was performed at the gastroenterology clinics of Marshall University, Huntington, WV; and West Virginia University. Charleston division, Charleston, WV The diagnosis of IBD was established according to clinical, radiologic, and endoscopic data. laboratory data and serum markers were recorded, and their accuracy to diagnose UC or CD was assessed. Results: A total of 101 charts were reviewed, of which only 90 (89% ) included serologic markers and were considered for further analysis. Disease distribution included: UC- 41, CD- 44, and indeterminate colitis (IC)- 7 (2 patients changed diagnosis after colectomy). Serum antibody pANCA had a sensitivity of 73% and specificity of 84% for UC, but only 16% and 35% for CD, respectively. Serum antibody ASCA had a sensitivity of 58% and specificity of 92% for CD, but only 7% and 49% for UC. respectively. The outer membrane porin to Escherichia coli antibody (anti- OmpC) was available in 54 (59% ) children and demonstrated a very poor sensitivity for both diseases (sensitivity< 11% ). Conclusion: Despite our homogeneous patient population, pANCA and ASCA antibodies had an inadequate sensitivity/specificity for children with UC or CD.

关键词：炎症性肠病血清学标志物西弗尼亚克罗恩病埃希大肠杆菌临床基础溃疡性结肠炎蛋白抗体结肠切除术