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Deep learning echocardiographic intelligent model for evaluation on left ventricular regional wall motion abnormality

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中国医学影像技术 2024年第8期40卷 1135-1139页

作者： WANG Yonghuai DONG Tianxin MA Chunyan department of cardiovascular Ultrasound the First Hospital of China Medical UniversityShenyang 110002China Clinical Medical Research Center of imaging in Liaoning Province Shenyang 110002China

Objective To observe the value of deep learning echocardiographic intelligent model for evaluation on left ventricular(LV)regional wall motion abnormalities(RWMA).Methods Apical two-chamber,three-chamber and four-chamber views two-dimensional echocardiograms were obtained prospectively in 205 patients with coronary heart *** model for evaluating LV regional contractile function was constructed using a five-fold cross-validation method to automatically identify the presence of RWMA or not,and the performance of this model was assessed taken manual interpretation of RWMA as *** Among 205 patients,RWMA was detected in totally 650 segments in 83 *** myocardial segmentation model demonstrated good efficacy for delineation of LV *** average Dice similarity coefficient for LV myocardial segmentation results in the apical two-chamber,three-chamber and four-chamber views was 0.85,0.82 and 0.88,*** myocardial segmentation model accurately segmented LV myocardium in apical two-chamber,three-chamber and four-chamber *** mean area under the curve(AUC)of RWMA identification model was 0.843±0.071,with sensitivity of(64.19±14.85)%,specificity of(89.44±7.31)%and accuracy of(85.22±4.37)%.Conclusion Deep learning echocardiographic intelligent model could be used to automatically evaluate LV regional contractile function,hence rapidly and accurately identifying RWMA.

关键词： ventricular function,left systolic function echocardiography deep learning

Preliminary clinical application of total free-breathing cardiac MR examination

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中国医学影像技术 2024年第8期40卷 1183-1188页

作者： YANG Kai YIN Gang AN Jing YANG Xinling LAN Tian ZHAO Shihua LU Minjie department of Magnetic Resonance imaging Fuwai HospitalNational Center for Cardiovascular DiseasesPeking Union Medical College and Chinese Academy of Medical SciencesBeijing 100037China Siemens Shenzhen Magnetic Resonance Ltd. Shenzhen 518057China Key Laboratory of cardiovascular imaging Chinese Academy of Medical SciencesBeijing 100730China

Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination *** Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding *** No significant difference of imaging quality was found between total free-breathing and conventional breath-holding *** differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were *** Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.

关键词： heart magnetic resonance imaging respiratory motion motion correction

Development and validation of a preoperative prediction model for all-cause mortality in patients following abdominal aortic aneurysm repair

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Chinese Medical Journal 2024年第10期137卷 1255-1257页

作者： Tan Li Guangxiao Li Yijun Wu Chao Yang Jun Yang Liping Sun Chunyan Ma department of cardiovascular Ultrasound The First Hospital of China Medical UniversityShenyangLiaoning 110001China Clinical Medical Research Center of imaging in Liaoning Province The First Hospital of China Medical UniversityShenyangLiaoning 110001China department of Medical Record Management Center The First Hospital of China Medical UniversityShenyangLiaoning 110001China Tumor Etiology and Screening department of Cancer Institute and General Surgery The First Hospital of China Medical UniversityShenyangLiaoning 110001China Trauma Center and department of Burns The First Hospital of China Medical UniversityShenyangLiaoning 110001China

To the Editor:Abdominal aortic aneurysm(AAA)is a life-threatening vascular *** intervention is typically recommended when the maximum AAA diameter reaches a threshold of 5.5cm for men and 5.0cm for women,or when an AAA experiences a rapid expansion of greater than 1.0cm/year.[1]Survival after AAA repair is inuenced by various factors,and the identication of independent prognostic factors and the development of accurate prediction models are crucial for optimal treatment planning,counseling,and postoperative *** several scoring systems with varying degrees of accuracy have been developed to predict the risk of mortality after intervention for patients with ruptured AAA.

关键词： patients mortality aneurysm

Asymptomatic recurrence in patients with pulmonary embolism

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Chinese Medical Journal 2024年第9期137卷 1118-1120页

作者： Song Hu Lei Wang Jiangshan Tan Wei Fang Xinghong Ma Tingting Guo Xin Gao Yan Wu Yuzi Zhou Li Wang Lu Hua State Key Laboratory of cardiovascular Disease National Center for Cardiovascular DiseasesFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China department of Nuclear Medicine National Center for Cardiovascular DiseasesFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Key Laboratory of Pulmonary Vascular Medicine Department of CardiologyNational Clinical Research Center of Cardiovascular DiseasesNational Center for Cardiovascular DiseasesFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Fuwai Shenzhen hospital Chinese Academy of Medical SciencesShenzhenGuangdong 518057China

To the Editor:Pulmonary embolism(PE)is the third most common cause of cardiovascular-related death worldwide after stroke and heart *** a consequence of hemodynamic differences,patients with PE present a wide spectrum of clinical manifestations,ranging from asymptomatic to life-threatening *** are high rates of recurrence in PE patients,and although most patients survive after the initial phase of the disease,the risk of recurrence remains throughout *** to patients experiencing theirrst PE episodes,patients with recurrent PE may be *** date,much of our knowledge about recurrent PE has come from clinical trials or registry studies in which symptomatic recurrence was a major endpoint,while asymptomatic recurrence is rarely ***,current guidelines suggest treating patients with asymptomatic PE similarly to those with symptomatic PE,[1,2]but do not recommend routine follow-up of asymptomatic patients by imaging methods after PE diagnosis.

关键词： patients routine clinical

Interaction between systemic iron parameters and left ventricular structure and function in the preserved ejection fraction population:a two-sample bidirectional Mendelian randomization study

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Journal of Geriatric Cardiology 2024年第1期21卷 64-80页

作者： Xiong-Bin MA Yong-Ming LIU Yan-Lin LV Lin QIAN The First Clinical Medical College of Lanzhou University LanzhouGansuChina Geriatric cardiovascular department and Gansu Clinical Research Center for Geriatric Diseases First Hospital of Lanzhou UniversityGansuChina

BACKGROUND Left ventricular(LV)remodeling and diastolic function in people with heart failure(HF)are correlated with iron status;however,the causality is *** Mendelian randomization(MR)study investigated the bidirectional causal relationship between systemic iron parameters and LV structure and function in a preserved ejection fraction *** Transferrin saturation(TSAT),total iron binding capacity(TIBC),and serum iron and ferritin levels were extracted as instrumental variables for iron parameters from meta-analyses of public genome-wide association *** without myocardial infarction history,HF,or LV ejection fraction(LVEF)cardiovascular Magnetic Resonance imaging Study constituted the outcome *** dataset included LV end-diastolic volume,LV endsystolic volume,LV mass(LVM),and LVM-to-end-diastolic volume ratio(LVMVR).We used a two-sample bidirectional MR study with inverse variance weighting(IVW)as the primary analysis method and estimation methods using different algorithms to improve the robustness of the *** In the IVW analysis,one standard deviation(SD)increased in TSAT significantly correlated with decreased LVMVR(β=-0.1365;95%confidence interval[CI]:-0.2092 to-0.0638;P=0.0002)after Bonferroni ***,no significant relationships were observed between other iron and LV *** Bonferroni correction,reverse MR analysis showed that one SD increase in LVEF significantly correlated with decreased TSAT(β=-0.0699;95%CI:-0.1087 to-0.0311;P=0.0004).No heterogeneity or pleiotropic effects evidence was observed in the *** We demonstrated a causal relationship between TSAT and LV remodeling and function in a preserved ejection fraction population.

关键词： fraction function parameters

Multimodal cardiac imaging assisted tumor characterization and surgical planning of a patient with rare primary cardiac paraganglioma

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Journal of Geriatric Cardiology 2024年第2期21卷 246-250页

作者： Shu-Yu MENG Li-Qun WANG Hao-Dan DANG Lin ZHANG Sheng-Li JIANG Bo-Han LIU department of Ultrasound Diagnosis the First Medical CenterChinese PLA General HospitalBeijingChina department of Nuclear Medicine the First Medical CenterChinese PLA General HospitalBeijingChina department of Pathology the First Medical CenterChinese PLA General HospitalBeijingChina department of cardiovascular Surgery the First Medical CenterChinese PLA General HospitalBeijingChina

Paragangliomas,also known as pheochromocytomas(1–9 cases per million),arise in the paraganglia.[1]Pheochromocytomas occur in the adrenal glands,while paragangliomas occur elsewhere.[2]Paragangliomas originate from paraganglion cells,which are derived from the neural ectoderm of the nerves and migrate along both sides of the median axis from the base of the skull to the pelvis during embryonic development.

关键词： glioma cardiac nerves

Circulating biomarker-and magnetic resonance-based nomogram predicting long-term outcomes in dilated cardiomyopathy

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Chinese Medical Journal 2024年第1期137卷 73-81页

作者： Yupeng Liu Wenyao Wang Jingjing Song Jiancheng Wang Yi Fu Yida Tang department of Cardiology Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China Guangdong cardiovascular Institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China department of Cardiology Institute of Vascular MedicinePeking University Third HospitalBeijing 100191China department of Cardiology State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems State Key Laboratory of Natural and Biomimetic DrugsSchool of Pharmaceutical SciencesPeking UniversityBeijing 100083China department of Physiology and Pathophysiology School of Basic Medical SciencesPeking University Health Science CenterBeijing 100083China Key Laboratory of Molecular cardiovascular Science Ministry of EducationBeijing 100191China

Background:Dilated cardiomyopathy(DCM)has a high mortality rate and is the most common indication for heart *** study sought to develop a multiparametric nomogram to assess individualized all-cause mortality or heart transplantation(ACM/HTx)risk in DCM ***:The present study is a retrospective cohort *** demographic,clinical,blood test,and cardiac magnetic resonance imaging(CMRI)data of DCM patients in the tertiary center(Fuwai hospital)were *** primary endpoint was ACM/*** least absolute shrinkage and selection operator(LASSO)Cox regression model was applied for variable *** Cox regression was used to develop a *** concordance index(C-index),area under the receiver operating characteristic curve(AUC),calibration curve,and decision curve analysis(DCA)were used to evaluate the performance of the ***:A total of 218 patients were included in the present *** were randomly divided into a training cohort and a validation *** nomogram was established based on eight variables,including mid-wall late gadolinium enhancement,systolic blood pressure,diastolic blood pressure,left ventricular ejection fraction,left ventricular end-diastolic diameter,left ventricular end-diastolic volume index,free triiodothyronine,and N-terminal pro-B type natriuretic *** AUCs regarding 1-year,3-year,and 5-year ACM/HTx events were 0.859,0.831,and 0.840 in the training cohort and 0.770,0.789,and 0.819 in the validation cohort,*** calibration curve and DCA showed good accuracy and clinical utility of the ***:We established and validated a circulating biomarker-and CMRI-based nomogram that could provide a personalized prediction of ACM/HTx for DCM patients,which might help risk stratification and decision-making in clinical practice.

关键词： Cardiomyopathy,dilated Heart transplantation Mortality Nomograms Least absolute shrinkage and selection operator Decision curve analysis

Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2724-2734页

作者： Song Fei Wei-Dong Wu Han-Shuo Zhang Shao-Jie Liu Dan Li Bo Jin department of Thoracic and cardiovascular Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina department of Gastrointestinal Surgery Guangzhou Red Cross Hospital of Jinan UniversityGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Neuroendocrine tumors(NETs)arise from the body’s diffuse endocrine *** primary adenocarcinoma of the colon and NETs of the duodenum(D-NETs)is a rare occurrence in clinical *** classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been *** SUMMARY We report the details of a case involving female patient with coexisting primary adenocarcinoma of the colon and a D-NET diagnosed by imaging and surgical *** tumors were treated by surgery and four courses of *** patient achieved a favorable clinical *** Coexisting primary adenocarcinoma of the colon and D-NET were diagnosed by imaging,laboratory indicators,and surgical *** resection com-bined with chemotherapy was a safe,clinically effective,and cost-effective treat-ment.

关键词： Neuroendocrine tumor of the duodenum Multiple primary tumors Colorectal cancer Endoscopic resection Case report

Transcatheter aortic valve replacement:A journey of two decades and beyond

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Chinese Medical Journal 2024年第9期137卷 1012-1015页

作者： Tianyuan Xiong Mao Chen department of Cardiology West China HospitalSichuan UniversityChengduSichuan 610041China Laboratory of Cardiac Structure and Function Institute of Cardiovascular DiseasesWest China HospitalSichuan UniversityChengduSichuan 610041China

The number of patients with calcic aortic stenosis(AS)is 9.4 million according to 2019 Global Disease Burden estimates,which will continue to increase as the population ages.[1]For the treatment of symptomatic severe AS,transcatheter aortic valve replacement(TAVR)has evolved to be a well-established option across all risk spectra,with a rapid growth of procedures *** rise of TAVR initiates the revolution of the management of valvular heart diseases,from patient surveillance,the staging of disease,the use of multimodality imaging,the concept of the Heart Team,new designs and iterations of devices to technical innovations and the discovery of unmet clinical *** a consequence of the global adoption of TAVR,geographical differences in the epidemiology of AS and patient characteristics have also been further identi*** examination of the changing patient population,current applications and breakthroughs,and remaining challenges are crucial for the future of this ***,we discuss the temporal utilization of TAVR,the accumulation of evidence and progress of devices,the selection of patients,and some ongoing topics concerning the improvement of TAVR.

关键词： epidemiology breakthrough beyond