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Clinical Study of P_(ET)CO_2 in One-lung Ventilation

Journal of Huazhong University of Science and Technology(Medical Sciences) 1996年第3期16卷 179-182页

作者：张传汉马自成金士翱 department of anethesiology Tongji Hospital Tongji Medical University Wuhan

Fourty-eight patients (ASA physical status Ⅰ - Ⅱ) undergoing selected thoracotomy and pulmonectomy were studied. They were divided into two groups according to different respiratory modes, two-lung ventilation (TLV) and onelung ventilation (OLV) or TLV and OLV with a Bain cyclic system for CPAP on the side of operated lung. PETCO2 and PaCO2 were measured after 30 min TLV,30 min and 60 min OLV, and repeated TLV (R-TLV) 30 min after pulmonectomy, to evaluate the difference between PETCO2 and PaCO2 in OLV and to observethe effect of abating hypoxemia and discharge of CO2 in OLV with Bain *** results showed that the PaCO2 and PETCO2 in different test groups were normal though the measured values in OLV were slightly higher than that in TLV (P0. 05). There was nosignificant difference between group 1. and 2. in OLV (P>0. 05). There was aclose correlation between PETCO2 and PaCO2 (P<0. 05). The differences of the calculated P(a-ET)CO2 and radio of PETCO2/PaCO2 in different ventilation modes were not significant. Hypoxemia in OLV was corrected by Bain system, but the discharge of CO2 was not affected. The results showed that measurement of PET CO2 as a non-invasive procedure can be commonly used to monitor OLV.

关键词： CO_2 partial pressure one-lung ventilation non-invasive monitoring

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A New adaptor to improve oxygenation and ventilation during bronchoscopy

A New adaptor to improve oxygenation and ventilation during ...

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2016中国中西医结合麻醉学会[CSIA]年会暨第三届全国中西医结合麻醉学术研讨会、河南省中西医结合学会麻醉专业委员会成立大会

作者： Tiegang Wei department of anethesiology Mudanjiang cancer HospitalMudanjiang Medical University

Background:Bronchoscopy is an increasing commonly procedure for diagnosis and treatment of various lung disease,but general anesthesia for the procedure is challenging because of sharing a common airwaybetween anesthesiologists and *** have successfully using a newly designed adaptor in combination with LMA to facilitate airway management during the bronchoscopy under general anesthesia.

关键词： A New adaptor to improve oxygenation and ventilation during bronchoscopy

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Application Research of Fragmented Case Teaching in Standardized Training of Residents in Anesthesiology department

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Journal of Clinical and Nursing Research 2023年第5期7卷 1-6页

作者： Xiaokai Zhou Jian Shen department of anethesiology and Perioperative Medicine Jiangsu Province HospitalNanjing 210029Jiangsu ProvinceChina

Objective:To explore the effect of fragmented case teaching in the standardized training of residents in anesthesiology ***:80 doctors who participated in the standardized training of residents in anesthesiology department from January 2021 to January 2022 were selected as the research objects,and the 80 doctors were divided into experimental groups according to the clinical teaching mode(n=40,implemented case fragmented teaching method)and the control group(n=40,traditional teaching method).The training lasted for 2 months,and the medical history collection,medical record analysis,practical operation ability,theoretical assessment results,and the degree of satisfaction towards the training of the two groups of doctors were ***:After 2 months of training,the theoretical knowledge and operational ability of the doctors in the two groups have improved to a certain extent,but the medical history collection,medical record analysis,practical operation ability,theoretical assessment results and satisfaction of the doctors in the experimental group were significantly better than those in the control group(P<0.05).Conclusion:The effect of the fragmented case teaching method in the standardized training of anesthesiology residents is significantly better than the traditional teaching *** abilities of doctors have significantly improved after the ***,the fragmented case teaching method is worthy of promotion in clinical practice.

关键词： Case fragmentation teaching Anesthesiology department Resident physician Standardized training Application

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Xiaoyu Jiangzhi capsule protects against heart failure via Ca^(2+)/CaMKII signaling pathways in mice

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Journal of Traditional Chinese Medical Sciences 2022年第3期9卷 289-297页

作者： Jianwei Wu Yafang Tan Dongyuan Kang Juan Yu Jianyong Qi Jiashin Wu Minzhou Zhang department of anethesiology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510006China Guangdong Province Hospital of Chinese Medicine Guangdong Province Academy of Chinese MedicineGuangzhou510006China nd Clinical Medical College Guangzhou University of Chinese MedicineGuangzhou510006China Animal Center Guangdong Province Academy of Chinese MedicineGuangzhou510006China College of Pharmacy Northeast Ohio Medical UniversityRootstown44272USA

Objective: Heart failure(HF), a worldwide health condition, is the result of many cardiovascular *** traditional Chinese medicine(TCM) Xiaoyu Jiangzhi capsule(XYC) has long been in use in China to treat hyperlipidemia and inhibit platelet aggregation. This study explores the effects of XYC on heart failure(HF) and its detailed ***: Isoproterenol(ISO, 30 mg/kg) was injected intraperitoneally for 7 days to copy a HF model of 10-12 weeks old, 20-30 g male mice. We then compared the CON(control) group, ISO(HF model)group, MET(metoprolol) group, and XYC group. Cardiac systolic function and left wall thickness were evaluated by echocardiograph. Using western blot analysis, we detected the proteins of calmodulin dependent protein kinase Ⅱ(Ca MKII) and sarco/endoplasmic reticulum Ca^(2+)-ATPase(Serca). Furthermore, ts A201 cells were cultured and the human CaV1.2 calcium channel current(hCaV1.2) were detected by patch clamp ***: XYC reduced HF, inhibiting the protein expression of Ca MKII, but Serca did not change significantly. Moreover, XYC inhibited the peak amplitude of the hCaV1.2 current, depolarizing shifted the activation curve 27.6 mV, and shifted the inactivation curve toward a positive potential 17.6 mV. The fraction recovered from inaction was reduced in XYC group compared with that in CON ***: XYC could inhibit ISO-induced HF by reducing the Ca^(2+)/Ca MKII signaling pathway in mice.

关键词： Heart failure CaV1.2 channel Patch clamp CaMKII Serca Traditional Chinese medicine Xiaoyu Jiangzhi capsule Mice

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