检索结果-南通市图书馆

Multi‑omics integration identifies regulatory factors underlying bovine subclinical mastitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2024年第3期15卷 987-1007页

作者： Mengqi Wang Naisu Yang Mario Laterriere David Gagne Faith Omonijo Eveline M.Ibeagha‑Awemu agriculture and agri‑Food Canada Sherbrooke Research and Development CentreSherbrookeQCCanada department of Animal Science Universite LavalQuebec CityQCCanada Quebec Research and Development Centre Agriculture and Agri-Food CanadaQuebec CityQCCanada

Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy ***-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease ***,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus *** Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical *** abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),***,5 factors presenting the principal variation of differential multi-omics signatures were *** important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were *** of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical ***,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regu

关键词： Candidate discriminant multi-omics signature Gene Long non-coding RNA Methylation haplotype block MicroRNA Multi-omics integration Natural killer cell mediated cytotoxicity pathway Staphylococcus aureus infection pathway

Gut microbiome and serum metabolome analyses identify Bacteroides fragilis as regulators of serotonin content and PRL secretion in broody geese

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative agriculture 2024年第6期23卷 2033-2051页

作者： Yu Zhang Ning Zhou Jia Wu Lina Song Qiang Bao Kaiqi Weng Yang Zhang Wanwipa Vongsangnak Guohong Chen Qi Xu College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Joint International Research Laboratory of agriculture&agri-Product Safety of Ministry of Education Yangzhou UniversityYangzhou 225009China department of Zoology Faculty of ScienceKasetsart UniversityBangkok 10900Thailand

Broody behavior is regulated by hypothalamic prolactin secretion,which seriously affects egg production in poulty *** studies have provided evidence that animal behavior is governed by dynamic bidirectional communication between specific gut bacteria and their host via the brain-gut-microbiome ***,little research focused on how the gut microbiota influence broody behavior in *** this study,Zhedong white geese in laying and brooding phases were *** differentially abundant bacteria in cecum were detected between brooding and laying geese through metagenomic analyses and 16S rRNA sequencing(P<0.05),and Bacteroides fragilis was specifically identified as a key driver species in the brooding ***,the serum metabolites were quantified,and the 313 differentially abundant metabolites were found between the two groups of different physiological *** were primarily enriched in the tryptophan metabolism *** correlation analyses revealed there was a significant positive correlation between *** abundance and the context of 11 tryptophan metabolism-related metabolites(such as serotonin,etc.)in broody geese,which hinted that those tryptophan metabolites might be produced or driven by ***,the serum hormone levels were also *** found there was a positive correlation between *** abundance and content of ***,prolactin secreted by the pituitary gland was greater in brooding geese than that in laying geese,which was also highly correlated with *** *** result implied that *** could promote the secretion of prolactin by the pituitary ***,the current study findings provided the information on gut microbiota influencing broody behavior,*** produced or driven more serum serotonin,and stimulated the pituitary gland to secret more prolactin,which potentially offered a new enlightenment for the intervention of broody behavior in pou

关键词： geese broody behavior gut microbiota serotonin prolactin

Pre-mating nitenpyram exposure in male mice leads to depression-like behavior in offspring by affecting tryptophan metabolism in gut microbiota

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第3期137卷 120-130页

作者： Sen Yan Wei Sun Sinuo Tian Zhiyuan Meng Jinling Diao Zhiqiang Zhou Li Li Wentao Zhu Innovation Center of Pesticide Research Department of Applied ChemistryCollege of ScienceChina Agricultural UniversityBeijing 100193China College of Plant Protection/Joint International Research Laboratory of agriculture&agri-Product Safety Yangzhou UniversityYangzhou 225009China College of Plant Protection Shanxi Agricultural UniversityTaiyuan 030031China

Several studies have confirmed that the health status of the paternal affects the health of the offspring,however,it remains unknown whether paternal exposure to pesticides affect the offspring ***,we used untargeted metabolomics and 16S rRNA sequencing technology,combined with tail suspension test and RT-qPCR to explore the effects of paternal exposure to nitenpyram on the neurotoxicity of *** results found that the paternal exposure to nitenpyram led to the offspring’s depressive-like behaviors,accompanied by the reduction of tryptophan content and the disorder of microbial abundance in the gut of the ***,we determined the expression of tryptophan metabolism-related genes tryptophanase(tnaA)and tryptophan hydroxylase 1(TpH1)in gut bacteria and colonic *** found that tryptophan is metabolized to indoles rather than being absorbed into colonocytes,which coursed the reduce of tryptophan availability after nitenpyram *** conclusion,our study deepens our understanding of the intergenerational toxic effects of pesticides.

关键词： Nitenpyram Depressive-like behaviors Gut microbiota Tryptophan metabolism

The first factor affecting dryland winter wheat grain yield under various mulching measures: Spike number

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative agriculture 2024年第3期23卷 836-848页

作者： Yingxia Dou Hubing Zhao Huimin Yang Tao Wang Guanfei Liu Zhaohui Wang Sukhdev Malhi Coliege of Natural Resources and Environment Northwest A&F UniversityYangling 712100China Key Laboratory of Plant Nutrition and the agri-Environment in Northwest China Ministry of Agriculture and Rural AffairsYangling 712100China department of Renewable Resources University of AlbertaEdmonton T6G 2H1Canada

Water is the key factor limiting dryland wheat grain *** affects crop yield and yield components by affecting soil *** research is needed to determine the relationships between yield components and soil moisture with yield,and to identify the most important factor affecting grain yield under various mulching measures.A long-term 9-yearifeld experiment in the Loess Plateau of Northwest China was carried out with three treatments:no mulch (CK),plastic mulch (M_(P)) and straw mulch (M_(S)).Yield factors and soil moisture were measured,and the relationships between them were explored by correlation analysis,structural equation modeling and significance *** results showed that compared with CK,the average grain yields of M_(P) and M_(S) increased by 13.0and 10.6%,*** average annual grain yield of the M_(P) treatment was 134 kg ha^(–1) higher than the M_(S) *** were no significant differences in yield components among the three treatments (P<0.05).Soil water storage of the M_(S) treatment was greater than the M_(P) treatment,although the differences were not statistically *** water storage during the summer fallow period (SWSSF) and soil water storage before sowing (SWSS) of M_(S) were significantly higher than in CK,which increased by 38.5 and 13.6%,*** relationship between M_(P) and CK was not statistically significant for SWSSF,but the SWSS in M_(P) was significantly higher than in *** terms of soil water storage after harvest (SWSH) and water consumption in the growth period(ET),there were no signi?cant differences among the three *** on the three analysis methods,we found that spike number and ET were positively correlated with grain ***,the relative importance of spike number to yield was the greatest in the M_(P )and M_(S) treatments,while that of ET was the greatest in *** SWSSF could indirectly increase spike number and ET in the three treatments.B

关键词： dryland winter wheat plastic mulch spike number straw mulch

Plastic mulch increases dryland wheat yield and water-use productivity,while straw mulch increases soil water storage

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative agriculture 2024年第9期23卷 3174-3185页

作者： Hubing Zhao Guanfei Liu Yingxia Dou Huimin Yang Tao Wang Zhaohui Wang Sukhdev Malhi Adnan Anwar Khan College of Natural Resources and Environment Northwest A&F UniversityYangling 712100China Key Laboratory of Plant Nutrition and the agri-environment in Northwest China Ministry of Agriculture and Rural AffairsYangling 712100China department of Renewable Resources University of AlbertaEdmonton T6G 2H1Canada

Amplifying drought stress and high precipitation variability impair dryland wheat *** problems can potentially be minimized by using plastic mulch(PM)or straw mulch(SM).Therefore,wheat grain yield,soil water storage,soil temperature and water-use productivity of PM and SM treatments were compared with no mulch(CK)treatment on dryland wheat over a period of eight *** to the CK treatment,PM and SM treatments on average significantly increased grain yield by 12.6 and 10.5%,*** to the CK treatment,SM treatment significantly decreased soil daily temperature by 0.57,0.60 and 0.48℃ for the whole seasons,growing periods and summer fallow periods,*** contrast,compared to the CK treatment,PM treatment increased soil daily temperature by 0.44,0.51 and 0.27℃ for the whole seasons,growing periods and summer fallow periods,*** soil temperature under SM allowed greater soil water storage than under *** water storage pre-seeding was 17%greater under the SM than under the PM *** water storage post-harvest was similar for the PM and SM treatments,but evapotranspiration was 4.5%higher in the SM than in the PM ***,water-use productivity was 6.6%greater under PM than under the SM ***,PM treatment increased dryland wheat yield and water-use productivity,while straw mulch increased soil water storage.

关键词： plastic mulch soil water storage straw mulch water-use productivity winter wheat

A Brassica carinata pan-genome platform for Brassica crop improvement

在线全文

学校读者我要写书评

暂无评论

Plant Communications 2024年第1期5卷 20-23页

作者： Yan Niu Qingqing Liu Zhesi He Rosy Raman Hao Wang Xinxin Long Han Qin Harsh Raman Isobel A.P.Parkin Ian Bancroft Jun Zou National Key Laboratory of Crop Genetic Improvement College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhanChina department of Biology University of YorkHeslingtonYork YO105DDUK NSW department of Primary Industries Wagga Wagga Agricultural InstituteWagga WaggaNSW 2650Australia agriculture and agri-Food Canada Saskatoon Research and Development CentreSaskatoonSKCanada

Dear Editor,Brassica carinata(Bc Bc Cc Cc),an important agricultural crop cultivated for the edible oil,leafy vegetable,high-value protein stockfeed,and biofuel markets,contains favorable genetic variation that can be exploited to develop climate-resilient and wateruse-efficient Brassica crops(Seepaul et al.,2021).Although several quantitative trait loci(QTLs)for flowering time,seed quality traits,and pod shatter resistance(PSR)have been identified based on high-density genetic linkage maps(Zou et al.,2014;Raman et al.,2017;Zhang et al.,2017),this information alone is insufficient for practical genetic improvement and breeding applications.

关键词： breeding crops cultivated

Assessing Moroccan physician knowledge and practices regarding maternal obesity's impact on childhood obesity:Implications for prevention and intervention

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Pediatrics 2024年第2期13卷 146-160页

作者： Imane Douiyeh Jihane Khamlich Naima Nabih Asmae Saih Ilham Boumendil Anas Regragui Anass Kettani Amal Safi Laboratory Biochemistry Environment and agri-food Department of BiologyFaculty of Science and Technics MohammediaHassanⅡUniversity CasablancaMohammedia 28806Morocco department of Biology Faculty of Sciences Ben M’Sik HassanⅡUniversity of CasablancaCasablanca 20000Morocco department of Medical ACHAS Association of the Doctors Ain Chock Casablanca MoroccoCasablanca 20400Morocco department of Medical HassanⅡUniversityCasablanca 20400Morocco

BACKGROUND Childhood obesity is a growing global concern with far-reaching health *** study focuses on evaluating the knowledge and practices of physicians in Morocco regarding the link between maternal obesity and childhood *** the increasing prevalence of childhood obesity worldwide,this issue remains inadequately addressed in the Moroccan *** To assess the awareness and practices of physicians in Morocco concerning the connection between maternal obesity and childhood *** The research encompasses a comprehensive survey of practicing physicians,revealing significant gaps in awareness and practices related to maternal *** Notably,a significant portion of doctors do not provide adequate guidance to overweight pregnant women,highlighting the urgency for targeted educational *** In conclusion,this research illuminates critical areas for improvement in tackling childhood obesity in *** addressing these gaps,fostering awareness,and enhancing medical practices,the healthcare system can contribute significantly to preventing childhood obesity and improving the overall health of future generations.

关键词： Childhood obesity Maternal obesity Management Prevention Screening

Fractal image analysis and bruise damage evaluation of impact damage in guava

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information Processing in agriculture 2024年第2期11卷 217-227页

作者： Than Htike Rattapon Saengrayap Hiroaki Kitazawa Saowapa Chaiwong School of Agro-Industry Mae Fah Luang UniversityChiang Rai 57100Thailand department of agriculture Ministry of AgricultureLivestock and Irrigation 11181Myanmar Integrated agri-Tech Ecosystem Research Group Mae Fah Luang UniversityChiang Rai 57100Thailand Institute of Food Research National Agriculture and Food Research OrganizationIbaraki 305-8642Japan

Impact bruise damage and quality of‘Gim Ju’guava were investigated for different drop heights and number of drops using fractal image *** the impact test,a stainless-steel metal ball(250 g)was dropped on fruit from three drop heights(0,0.3,0.6 m)either once or five *** quality was evaluated for impact energy,bruise area(BA),bruise volume(BV),bruise susceptibility,bruise score and pulp color(L*,a*,b*and C values).The fractal dimension(FD)value using fractal image analysis was analyzed at the bruise *** showed that five drops(0.3 m)with a high impact energy(3678.75 J)and a single drop(0.6 m)with a low impact energy(1471.50 J)exhibited no significant in BA,BV,bruise score as well as all color values(L*,a*,b*and C).While the FD value of a single drop from 0.6 m had a higher FD value than that of five drops from 0.3 *** is indicated that FD exhibited a better performance to classify impact bruising level of guava than BA,BV and color *** FD value gradually decreased with increase of storage time and bruise *** correlation coefficient(r)values of FD(r=−0.794 and−0.745)between BA and BV were more significant than those L*(r=−0.660 and−0.615)and a*(r=0.579 and 0.473).The coefficient of determination(R^(2))of the polynomial equation in bruised fruit(R^(2)=0.85 to 0.99)was greater than the control(no bruise)(R^(2)=0.80).A higher R^(2)val(0.88 and 0.92)was exhibited at five ***,FD analysis showed greater potential than color measurement to assess bruise impact damage in guava.

关键词： Bruise susceptibility Impact bruise Mechanical injury Transportation

Inhibitory effect and mechanism of tannic acid against two starch digestive enzymes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Quality and Safety 2024年第1期8卷 115-123页

作者：钟毓秀倪德让杨玉波李元一王莉田金虎杨帆叶兴乾 department of Food Science and Nutrition Zhejiang Key Laboratory for Agri-Food ProcessingFuli Institute of Food ScienceZhejiang R&D Centre for Food Technology and EquipmentZhejiang UniversityHangzhouChina Institute of Science and Technology Moutai GroupZunyiChina Key Laboratory of Industrial Microbial Resources Development Kweichow Moutai Co.Ltd.RenhuaiChina

Backgrounds:Tannic acid(TA),as a plant-derived phenolic substance,is involved in regulating the activity of starch digestive enzymes,but its underlying mechanism remains *** and Results:In the present study,inhibition rate and inhibition kinetics assays were performed and confrmed that TA had a strong inhibitory effect on bothα-amylase andα-glucosidase with IC50 values of 0.1585 mg/mL and 0.00542 mg/mL,respectively,through a mixed inhibition *** secondary structures of both enzymes were confrmed to be modifed by TA through circular dichroism(CD)*** quenching analysis revealed that the interaction between TA and two enzymes was a static process of pontaneous complex ***,molecular docking revealed that non-covalent bonds were the main interaction forces between TA and both ***:Thus,TA was a promising candidate for the inhibition of starch-digesting enzymes,and the present research provided insight into postprandial glucose regulation through polyphenols.

关键词： Tannic acid α-amylase α-glucosidase inhibition starch digestion.