检索结果-南通市图书馆

Gender disparities and woman-specific trends in Barrett’s esophagus in the United States:An 11-year nationwide populationbased study

引用

World Journal of Methodology 2025年第1期15卷 60-71页

作者： Karina Fatakhova Faisal Inayat Hassam Ali Pratik Patel Attiq Ur Rehman Arslan Afzal Muhammad Sarfraz Shiza Sarfraz Gul Nawaz Ahtshamullah Chaudhry Rubaid Dhillon Arthur Dilibe Benjamin Glazebnik Lindsey Jones Emily Glazer Division of Gastroenterology and Hepatology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States department of Internal medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Gastroenterology and Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States department of Internal medicine East Carolina University Brody School of MedicineGreenvilleNC 27834United States department of Internal medicine St.Dominic's HospitalJacksonMS 39216United States department of Gastroenterology Hepatologyand NutritionCleveland Clinic FoundationClevelandOH 44195United States department of Internal medicine Mather Hospital and Hofstra University ZuckerSchool of MedicinePort JeffersonNY 11777United States

BACKGROUND Barrett's esophagus(BE)is a known premalignant precursor to esophageal adenocarcinoma(EAC).The prevalence rates continue to rise in the United States,but many patients who are at risk of EAC are not *** practice guidelines include male gender as a predisposing factor for BE and *** population-based clinical evidence regarding female gender remains *** To study comparative trends of gender disparities in patients with BE in the United *** A nationwide retrospective study was conducted using the 2009-2019 National Inpatient Sample(NIS)*** with a primary or secondary diagnosis code of BE were *** major outcome of interest was determining the gender disparities in patients with *** analysis for respective outcomes for females was also reported to ascertain any time-based *** We identified 1204190 patients with BE for the study *** the included patients,717439(59.6%)were men and 486751(40.4%)were *** mean age was higher in women than in men(67.1±0.4 vs 66.6±0.3 years,P<0.001).The rate of BE per 100000 total NIS hospitalizations for males increased from 144.6 in 2009 to 213.4 in 2019(P<0.001).The rate for females increased from 96.8 in 2009 to 148.7 in 2019(P<0.001).There was a higher frequency of obesity among women compared to men(17.4%vs 12.6%,P<0.001).Obesity prevalence among females increased from 12.3%in 2009 to 21.9%in 2019(P<0.001).A lower prevalence of smoking was noted in women than in men(20.8%vs 35.7%,P<0.001).However,trend analysis showed an increasing prevalence of smoking among women,from 12.9%in 2009 to 30.7%in 2019(P<0.001).Additionally,there was a lower prevalence of alcohol abuse,Helicobacter pylori(***),and diabetes mellitus among females than males(P<0.001).Trend analysis showed an increasing prevalence of alcohol use disorder and a decreasing prevalence of *** and diabetes mellitus among women(P<0.001).CONCLUSION The prevalence of BE among

关键词： Barrett’s esophagus Gender disparity Epidemiological trends Esophageal adenocarcinoma Screening endoscopy Female gender Risk factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Changing Patterns of Mortality in Diabetes Mellitus Among Older Adults—China,1987-2021

引用

China CDC weekly 2023年第50期5卷 1120-1124页

作者： Chen Chen Yihao Zhao Shangjun Liu Yu Wu Shan Yang Binbin Su Xiaoying Zheng department of population health and Aging science School of Population Medicine and Public HealthChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina department of Chronic Diseases and Multimorbidity School of Population Medicine and Public HealthChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Institute of population Research Peking UniversityBeijingChina department of Health Economics School of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina HeSAY/Institute of population Research Peking UniversityBeijingChina

What is already known about this topic?Diabetes mellitus poses a significant public health concern for older adults in China,resulting in increased mortality *** is added by this report?This study investigates the evolving pattern of mortality associated with diabetes mellitus and analyzes the contributions of age,period,and cohort effects from 1987 to *** results demonstrate a consistent rise in diabetes mellitus mortality over the last 30 years,notably in rural *** are the implications for public health practice?This research offers valuable insights to aid policymakers in developing targeted intervention strategies that address the specific needs of higher-risk populations,such as women,older adults,and individuals in rural areas.

关键词： mortality Diabetes policy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

引用

Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury I.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye Institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA department of medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and Imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characterizing functional consequences of DNA copy number alterations in breast and ovarian tumors by spaceMap

引用

Journal of Genetics and Genomics 2018年第7期45卷 361-371页

作者： Christopher J.Conley Umut Ozbek Pei Wang Jie Peng department of Statistics University of California Davis department of population Health Science and Policy Icahn School of Medicine at Mount Sinai department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai

We propose a novel conditional graphical model -- spaceMap -- to construct gene regulatory networks from multiple types of high dimensional omic profiles. A motivating application is to characterize the perturbation of DNA copy number alterations （CNAs） on downstream protein levels in tumors. Through a penalized multivariate regression framework, spaceMap jointly models high dimensional protein levels as responses and high dimensional CNAs as predictors. In this setup, spaceMap infers an undirected network among proteins together with a directed network encoding how CNAs perturb the protein network, spaceMap can be applied to learn other types of regulatory relationships from high dimensional molecular profiles, especially those exhibiting hub structures. Simulation studies show spaceMap has greater power in detecting regulatory relationships over competing methods. Additionally, spaceMap includes a network analysis toolkit for biological interpretation of inferred networks. We applies spaceMap to the CNAs, gene expression and proteomics data sets from CPTAC-TCGA breast （n = 77） and ovarian （n = 174） cancer studies. Each cancer exhibits disruption of＇ion transmembrane transport＇ and ＇regulation from RNA polymerase lI promoter＇ by CNA events unique to each cancer. Moreover, using protein levels as a response yields a more functionally-enriched network than using RNA expressions in both cancer types. The network results also help to pinpoint crucial cancer genes and provide insights on the functional consequences of important CNA in breast and ovarian cancers.

关键词： Integrative genomics Proteogenomics Conditional graphical models Network analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A novel Rad gene polymorphism combined with obesity increases risk for type 2 diabetes mellitus

引用

Chinese Medical Journal 2004年第5期117卷 770-771页

作者：王国英牛天华陈常忠李琼芳徐希平 department of Endocrinology Program for population Genetics

The ras-associated diabetes (Rad) was initially identified by subtraction cloning from the skeletal muscle of humans with non-insulin dependent diabetes mellitus (type 2 DM).1 Rad mRNA expression is markedly increased... 详细信息

关键词： Rad gene·obesity · polymorphism·type 2 diabetes mellitus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Long-Term Patterns of Meningitis Mortality:A Continual Downward Trend and a Vulnerable Infant population—China,1987–2021

引用

China CDC weekly 2023年第34期5卷 745-750页

作者： Yu Wu Huiyun Fan Binbin Su Chao Guo Luzhao Feng department of population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina APEC Health Science Academy(HeSAY) Peking UniversityBeijingChina Institute of population Research Peking UniversityBeijingChina department of Infectious Diseases School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina.

Summary What is already known about this topic?Meningitis,a life-threatening disease,presents a significant public health *** rate of progress in burden reduction notably lags behind other diseases that can be prevented through *** is added by this report?This research explored the changes in the mortality rate of meningitis in China over a span of 35 *** study further identified the effects of age,period,and cohort on the mortality trends.

关键词： mortality diseases vaccination

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Activities of Daily Living-Related Functional Impairment Among population Aged 65 and Older—China,2011–2050

引用

China CDC weekly 2023年第27期5卷 593-598页

作者： Binbin Su Panliang Zhong Chen Chen Yu Wu Xiaoying Zheng School of population medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina department of population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina

Summary What is already known about this topic?The elevated prevalence of functional impairment among elderly individuals in China contributes to an increased burden of *** is added by this report?This report presents a comprehensive evaluation of trends in functional impairment related to activities of daily living(ADL)among the elderly population in ***,it offers insights for future projections of these trends in this demographic *** are the implications for public health practice?Addressing the care needs and functional impairment issues among the aging population in China necessitates interdepartmental collaboration.

关键词： population demographic elderly

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Systematic overview of hepatitis C infection in the Middle East and North Africa

引用

World Journal of Gastroenterology 2018年第27期24卷 3038-3054页

作者： Karima Chaabna Sohaila Cheema Amit Abraham Hekmat Alrouh Albert B Lowenfels Patrick Maisonneuve Ravinder Mamtani Institute for population Health Weill Cornell Medicine-Qatar department of Surgery and the department of Family medicine New York Medical College Division of Epidemiology and Biostatistics European Institute of Oncology

AIM To assess the quality of and to critically synthesize the available data on hepatitis C infections in the Middle East and North Africa(MENA) region to map evidence *** We conducted an overview of systematic reviews(SRs) following an a priori developed protocol(CRD42017076736). Our overview followed the preferred reporting items for systematic reviews and metaanalyses guidelines for reporting SRs and abstracts and did not receive any funding. Two independent reviewers systematically searched MEDLINE and conducted a multistage screening of the identified articles. Out of 5758 identified articles, 37 SRs of hepatitis C virus(HCV) infection in populations living in 20 countries in the MENA region published between 2008 and 2016 were included in our overview. The nine primary outcomes of interest were HCV antibody(anti-) prevalences and incidences in different at-risk populations; the HCV viremic(RNA positive) rate in HCV-positive individuals; HCV viremic prevalence in the general population(GP); the prevalence of HCV co-infection with the hepatitis B virus, human immunodeficiency virus, or schistosomiasis; the HCV genotype/subtype distribution; and the risk factors for HCV transmission. The conflicts of interest declared by the authors of the SRs were also extracted. Good quality outcomes reported by the SRs were defined as having the population, outcome, study time and setting defined as recommended by the PICOTS framework and a sample size > *** We included SRs reporting HCV outcomes with different levels of quality and precision. A substantial proportion of them synthesized data from mixed populations at differing levels of risk for acquiring HCV or at different HCV infection stages(recent and prior HCV transmissions). They also synthesized the data over long periods of time(e.g., two decades). Anti-HCV prevalence in the GP varied widely in the MENA region from 0.1%(study dates not reported) in the United Arab Emirates to 2.1%-13.5%(2003-2006) in

关键词： Hepatitis C meta-research risk factors incidence genotype Middle East and North Africa systematic review Micro-elimination Pakistan Gulf Cooperation Council

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Changing Patterns of Mortality in Viral Hepatitis——China,1987–2021

引用

China CDC weekly 2023年第42期5卷 933-937页

作者： Chen Chen Zuliyaer Talifu Yu Wu Binbin Su Wanwei Dai department of population health and Aging science School of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina School of population medicine and Public Health Chinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina department of Health economics School of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina Office of Academic Research of Peking University Third Hospital BeijingChina

Summary What is already known about this topic?Viral hepatitis continues to present a major global public health challenge,with China shouldering the heaviest burden of this disease *** is added by this report?This study examined evolving trends and assessed the impacts of age,period,and cohort on viral hepatitis mortality from 1987 to 2021 in both urban and rural settings across *** are the implications for public health practice?This research provides critical insights,enabling policymakers to develop precise and effective intervention strategies that are specifically tailored to address the needs of high-risk older adults.

关键词： mortality precise policy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evidence base of randomized controlled trials and guideline recommendations of patent Traditional Chinese medicines for uncomplicated acute lower respiratory tract infections in adults

引用

Journal of Traditional Chinese medicine 2018年第4期38卷 490-503页

作者： Xia Ruyu Hu Xiaoyang Wang Di Wang Ying Merlin Willcox Liu Jianping Michael Moore Andrew Flower Li Xun Lily Lai Hu Ruixue Wen Lingzi Zhang Lishan Wang Qi Fei Yutong Centre for Evidence-Based Chinese medicine Beijing University of Chinese Medicine Primary Care and population Sciences University of Southampton Respiratory department Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine Respiratory department Dongfang Hospital Affiliated to Beijing University of Chinese Medicine

OBJECTIVE:To compare clinical practice guideline recommendations on the use of oral patent Traditional Chinese medicines(PTCMs) for uncomplicated acute lower respiratory tract infections(ALRTIs)in adults with the existing evidence using results of a systematic review of randomized controlled trials(RCTs).METHODS:A systematic review on RCTs and a systematic review of current guidelines on orally taken PTCMs for uncomplicated ALRTIs were *** Med,Cochrane Library,EMBASE and four Chinese databases were searched from inception to September 2016 for RCTs testing orally taken PTCMs for uncomplicated ALRTIs(excluding pneumonia).Two reviewers independently screened each study,extracted study data,and assessed risk of *** were resolved through discussion or by consultation with a third *** practice guidelines for uncomplicated ALRTIs containing PTCM recommendations were identified and quality *** quality of pooled evidence of the RCTs and the guidelines was assessed with GRADE and AGREE Ⅱ *** consistency of the evidence base in RCTs and the guideline recommendations were then ***:For the systematic review of RCTs,4810 papers were identified,among which 29 RCTs(5093 patients) were included in the *** compared to placebo increased the effective treatment rate of cough(3 trials,949 patients,risk ratio(RR) 2.50,1.16 to 5.43;low certainty);improved assessment of global health(3 trials,948 patients,RR1.70,1.44 to 2.01;low certainty);and increased the effective rate of specific symptom relief(1 trial,478 patients,RR 4.01,2.76 to 5.81;moderate certainty).21 trials(3432 patients) compared effects of different *** the guideline evaluation,29 PTCMs were recommended for the use of uncomplicated ALRTIs,of which27 had no supportive evidence from ***:The evidence base of PTCMs for uncomplicated ALRTIs is weak and the guideline recommendations were based on almost no clinical trial evidence.

关键词： Traditional Chinese medicine Acutelower respiratory tract infections Antibiotic Ay-stematic review Guideline

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：