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Dynamics of perinuclear actin ring regulating nuclear morphology

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Applied Mathematics and mechanics(English Edition) 2024年第8期45卷 1415-1428页

作者： Haoxiang YANG Houbo SUN Jinghao SHEN Hao WU Hongyuan JIANG CAS Key Laboratory of Mechanical Behavior and design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230026China

Cells are capable of sensing and responding to the extracellular mechanical microenvironment via the actin *** vivo,tissues are frequently subject to mechanical forces,such as the rapid and significant shear flow encountered by vascular endothelial ***,the investigations about the transient response of intracellular actin networks under these intense external mechanical forces,their intrinsic mechanisms,and potential implications are very ***,we observe that when cells are subject to the shear flow,an actin ring structure could be rapidly assembled at the periphery of the *** gain insights into the mechanism underlying this perinuclear actin ring assembly,we develop a computational model of actin *** demonstrate that this perinuclear actin ring assembly is triggered by the depolymerization of cortical actin,Arp2/3-dependent actin filament polymerization,and myosin-mediated actin network ***,we discover that the compressive stress generated by the perinuclear actin ring could lead to a reduction in the nuclear spreading area,an increase in the nuclear height,and a decrease in the nuclear *** present model thus explains the mechanism of the perinuclear actin ring assembly under external mechanical forces and suggests that the spontaneous contraction of this actin structure can significantly impact nuclear morphology.

关键词： mechanical force actin dynamics perinuclear actin ring compressive stress nucleus

A design and manufacturing methodology for encoded soft-textile robots

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Science China(Physics,mechanics & Astronomy) 2024年第5期67卷 212-213页

作者： Yihui Zhang Applied mechanics Laboratory Department of Engineering MechanicsTsinghua UniversityBeijing 100084China

The development of programmable soft robots with bioinspired morphing capabilities has attracted considerable *** mode and complexity of morphing capabilities are essential to the manipulation and movement abilities o... 详细信息

关键词： environments robots manipulation

A strategy to drive nanoflow using Laplace pressure and the end effect

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Droplet 2024年第3期3卷 107-113页

作者： Keli Zhang Hengyu Xu Jingcun Fan Cancan Ouyang Hengan Wu Fengchao Wang CAS Key Laboratory of Mechanical Behavior and design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefeiChina

Nanofluidics holds significant potential across diverse fields,including energy,environ-ment,and ***,the fundamental driving mechanisms on the nanoscale remain elusive,underscoring the crucial importance of exploring nanoscale driving *** study introduces a Laplace pressure-driven flow method that is accurately controlled and does not interfere with interfacial ***,we first confirmed the applicability of the Young–Laplace equation for droplet radii ranging from 1 to 10 *** that,a steady-state liquid flow within the carbon nanotube was attained in molecular dynamics *** flow was driven by the Laplace pressure difference across the nanochannel,which originated from two liquid droplets of unequal sizes positioned at the channel ends,***,we employ the Sampson formula to rectify the end effect,ultimately deriving a theoretical model to quantify the flow rate,which satisfactorily describes the molecular dynamics simu-lation *** research enhances our understanding on the driving mechanisms of nanoflows,providing valuable insights for further exploration in fluid dynamics on the nanoscale.

关键词： flow holds satis

Bioinspired 3D flexible devices and functional systems

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National Science Review 2024年第3期11卷 271-295页

作者： Xu Cheng Zhangming Shen Yihui Zhang Applied mechanics Laboratory Department of Engineering Mechanics Tsinghua University Laboratory of Flexible Electronics Technology Tsinghua University

Flexible devices and functional systems with elaborated three-dimensional(3D) architectures can endow better mechanical/electrical performances, more design freedom, and unique functionalities, when compared to their two-dimensional(2D) counterparts. Such 3D flexible devices/systems are rapidly evolving in three primary directions, including the miniaturization, the increasingly merged physical/artificial intelligence and the enhanced adaptability and capabilities of heterogeneous *** challenges exist in this emerging research area, such as relatively poor controllability in the locomotion of soft robotic systems, mismatch of bioelectronic interfaces, and signal coupling in multi-parameter sensing. By virtue of long-time–optimized materials, structures and processes, natural organisms provide rich sources of inspiration to address these challenges, enabling the design and manufacture of many bioinspired 3D flexible devices/systems. In this Review, we focus on bioinspired 3D flexible devices and functional systems, and summarize their representative design concepts, manufacturing methods, principles of structure-function relationship and broad-ranging applications. Discussions on existing challenges, potential solutions and future opportunities are also provided to usher in further research efforts toward realizing bioinspired 3D flexible devices/systems with precisely programmed shapes,enhanced mechanical/electrical performances, and high-level physical/artificial intelligence.

关键词： bioinspired designs biomimetic 3D structures 3D flexible electronics 3D functional systems direct 3D manufacture 2D-to-3D assembly

Molecular Dynamics Simulations of Displacement Cascade in Ni-Based Concentrated Solid Solution Alloys

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Acta Mechanica Solida Sinica 2024年第1期37卷 82-89页

作者： Chaoquan Zhao Rongxuan Xie Chuanlong Xu Xiaobao Tian Qingyuan Wang Wentao Jiang Haidong Fan department of mechanics Sichuan UniversityChengdu 610065China

Single-phase concentrated solid solution alloys(SP-CSAs),including high-entropy alloys,have received extensive attention due to their excellent irradiation *** this work,displacement cascade simulations are conducted using the molecular dynamics method to study the evolution of defects in Ni-based *** with pure Ni,the NiCr,NiCo,and NiCu alloys exhibit a larger number of Frankel pairs(FPs)in the thermal peak stage,but a smaller number of surviving ***,the NiFe alloy displays the opposite *** explain these different observations for NiFe and other alloys,the formation energy and migration energy of interstitials/vacancies are *** the NiFe alloy,both the formation energy and migration energy barrier are *** the other hand,in NiCr and other alloys,the formation energy of interstitials/vacancies is lower,as is the migration energy barrier of *** energy analysis agrees well with previous *** present work provides new insights into the mechanism behind the irradiation resistance of binary Ni-based SP-CSAs.

关键词： Molecular dynamics simulation Displacement cascade Point defect Ni-based concentrated solid solution alloys

A vibration isolator with a controllable quasi-zero stiffness region based on nonlinear force design

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Applied Mathematics and mechanics(English Edition) 2024年第8期45卷 1279-1294页

作者： Xinyu LIAN Bing LIU Huaxia DENG Xinglong GONG CAS Key Laboratory of Mechanical Behavior and design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Nonlinear mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei 230026China

To achieve stability optimization in low-frequency vibration control for precision instruments,this paper presents a quasi-zero stiffness(QZS)vibration isolator with adjustable nonlinear ***,the stress-magnetism coupling model is established through meticulous theoretical *** controllable QZS interval is constructed via parameter design and magnetic control,effectively segregating the high static stiffness bearing section from the QZS vibration isolation ***,a displacement control scheme utilizing a magnetic force is proposed to regulate entry into the QZS working range for the vibration isolation *** results demonstrate that the operation within this QZS region reduces the peak-to-peak acceleration signal by approximately 66.7%compared with the operation outside this region,thereby significantly improving the low frequency performance of the QZS vibration isolator.

关键词： low frequency nonlinear vibration isolator quasi-zero stiffness(QzS)

Granular collapse in fluids:Dynamics and flow regime identification

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Particuology 2024年第9期92卷 30-41页

作者： Hu Tang Bisong Lin Dengming Wang department of mechanics and Engineering Science School of Civil Engineering and MechanicsKey Laboratory of Mechanics on Disaster and Environment in Western China of Ministry of EducationLanzhou UniversityLanzhou730000China

The collapse of granular material in fluids is a prevalent phenomenon in both natural and industrial processes,displaying a notable sensitivity to initial configuration of the *** study is specifically oriented towards falling process of collapsing material under various fluid conditions,employing the computational fluid dynamics-discrete element method(CFD-DEM)to primarily investigate the dynamics and scaling laws of deposit morphology of collapsed *** a comprehensive analysis of particle sedimentation in fluids,we introduce a refined inertial characteristic time for granular collapse within the inertial ***,we propose modifications to conventional fluid-particle density ratio and Reynolds number,aiming to enhance the accuracy of depicting collapse dynamics and identifying flow regimes across diverse column heights and fluid ***,we construct a phase diagram of flow regimes using modified dimensionless numbers,emphasizing the role of column height in transition between viscous and inertial *** parameters demonstrate enhanced relevance in governing the collapse of immersed granular columns,thereby contributing to a more nuanced understanding of fluid-particle interations in dense granular flows under different regimes.

关键词： Immersed granular material Collapse Dynamic Flow regime Computational fluid dynamics-discrete element method

A physics-informed neural network for simulation of finite deformation in hyperelastic-magnetic coupling problems

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Applied Mathematics and mechanics(English Edition) 2024年第10期45卷 1717-1732页

作者： WANG Lei LUO Zikun LU Mengkai TANG Minghai department of Engineering mechanics College of Mechanics and Engineering SciencesHohai UniversityNanjing 211100China School of Mechanical Engineering and mechanics Ningbo UniversityNingbo 315211Zhejiang ProvinceChina

Recently,numerous studies have demonstrated that the physics-informed neural network(PINN)can effectively and accurately resolve hyperelastic finite deformation *** this paper,a PINN framework for tackling hyperelastic-magnetic coupling problems is *** the solution space consists of two-phase domains,two separate networks are constructed to independently predict the solution for each phase *** addition,a conscious point allocation strategy is incorporated to enhance the prediction precision of the PINN in regions characterized by sharp *** the developed framework,the magnetic fields and deformation fields of magnetorheological elastomers(MREs)are solved under the control of hyperelastic-magnetic coupling *** examples are provided and contrasted with the reference results to validate the predictive accuracy of the proposed ***,the advantages of the proposed framework in solving hyperelastic-magnetic coupling problems are validated,particularly in handling small data sets,as well as its ability in swiftly and precisely forecasting magnetostrictive motion.

关键词： physics-informed neural network(PINN) deep learning hyperelastic-magnetic coupling finite deformation small data set

Analysis of piezoelectric semiconductor fibers under gradient temperature changes

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Applied Mathematics and mechanics(English Edition) 2024年第2期45卷 311-320页

作者： Shuangpeng LI Ruoran CHENG Nannan MA Chunli ZHANG department of Engineering mechanics Zhejiang UniversityHangzhou 310027China

Piezoelectric semiconductors(PSs)possess both semiconducting properties and piezoelectric coupling effects,making them optimal building blocks for semiconductor *** fiber-like structures have wide applications in multi-functional semiconductor *** this paper,a one-dimensional(1D)theoretical model is established to describe the piezotronic responses of a PS fiber under gradient temperature *** theoretical model aims to explain the mechanism behind the resistance change caused by such gradient temperature *** results demonstrate that a gradient temperature change significantly affects the physical fields within the PS fiber,and can induce changes in its surface *** provides important theoretical guidance on the development of piezotronic devices that are sensitive to temperature effects.

关键词： piezoelectric semiconductor(PS)fiber one-dimensional(1D)model piezotronic effect gradient temperature change