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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1711-1728页

作者： Jing-doo Wang Chayadi Oktomy Noto Susanto departement of Computer Science and Information Engineering Asia UniversityTaichungTaiwanChina departement of Information Technology Universitas Muhammadiyah YogyakartaYogyakartaIndonesia

A significant obstacle in intelligent transportation systems(ITS)is the capacity to predict traffic *** advancements in deep neural networks have enabled the development of models to represent traffic flow ***,accurately predicting traffic flow at the individual road level is extremely difficult due to the complex interplay of spatial and temporal *** paper proposes a technique for predicting short-term traffic flow data using an architecture that utilizes convolutional bidirectional long short-term memory(Conv-BiLSTM)with attention *** studies neglected to include data pertaining to factors such as holidays,weather conditions,and vehicle types,which are interconnected and significantly impact the accuracy of forecast *** addition,this research incorporates recurring monthly periodic pattern data that significantly enhances the accuracy of forecast *** experimental findings demonstrate a performance improvement of 21.68%when incorporating the vehicle type feature.

关键词： Traffic flow prediction sptiotemporal data heterogeneous data Conv-BiLSTM data-centric intra-data

Epidemiological, Clinical, Therapeutic, and Evolutionary Aspects of Heart Failure in the Medical department at Gao Regional Hospital

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World Journal of Cardiovascular diseases 2024年第5期14卷 309-321页

作者： Coulibaly Alhousseny dollo Ibrahim Guindo Hamadoun Sidibé Lamine Mariko Souleymane Traoré Bassirima dao Karim Guindo Ibrahim Togo Mamadou Sidibé Samba Sangaré Ibrahima Ba Hamidou Oumar Ichiaka Menta departement of Medicine Gao Hospital Gao Mali departement of Medicine Mopti Regional Hospital Mopti Mali departement of Medicine Tombouctou Hospital Tombouctou Mali departement of Cardiology CHU Gabriel TOURE Bamako Mali

Introduction: Heart failure is a major public health pandemic, particularly in Africa, where its prevalence continues to increase. In northern Mali, few data exist, hence the interest of this study with the objective of studying the epidemiological, clinical and therapeutic and evolutionary aspects of Heart failure at the regional hospital of Gao. Patients and Methods: This was a cross-sectional, descriptive study that took place from July 2022 to June 2023 in the medical department at Gao Hospital. Results: The hospital prevalence of heart failure was 44.1%. The mean age was 47.30 ± 20 years (range: 16-88). Hypertension was the most common with 46.1%, followed by a sedentary lifestyle, and diabetes with 18.2% and 8.3% respectively;NYHA stage III-IV dyspnea was found in 83.9%. Reduced EF heart failure was present in 110 patients (76.9%), seventeen cases with moderately reduced EF (11.9%) and sixteen patients had preserved EF (11.2%). Global heart failure was the dominant (91.6%). The main etiologies of heart failure were dominated by hypertensive heart disease in 46 patients (32.2%), followed by postpartum cardiomyopathy with 43 cases (30.1%), primary dilated cardiomyopathy in 18 patients (12.6%), ischemic heart disease in 16 patients with 11.2%. Seven cases of valvular heart disease, or 4.9%. The evolution was favorable under treatment in 104 patients or 72.7%. In-hospital mortality was 14.7%. Conclusion: Heart failure is a common condition in sub-Saharan Africa, particularly in our country.

关键词： Heart Failure Epidemioclinical Progressive Gao Hospital

On stability behaviors of 5d M-theory black objects

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Communications in Theoretical Physics 2024年第5期76卷 94-101页

作者： Adil Belhaj Abderrahim Bouhouch departement de Physique Equipe des Sciences de la matiere et du rayonnementESMaR Faculte des SciencesUniversite Mohammed V de RabatRabatMorocco

Using N=2 supergravity formalism,we investigate certain behaviors of five-dimensional black objects from the compactification of M-theory on a Calabi-Yau *** manifold has been constructed as the intersection of two homogeneous polynomials of degrees(ω+2,1)and(2,1)in a product of two weighted projective spaces given by WP^(4)(ω,1,1,1,1)×P^(1).First,we determine the allowed electric charge regions of the BPS and non BPS black holes obtained by wrapping M2-branes on appropriate two cycles in such a proposed Calabi-Yau *** that,we calculate the entropy of these solutions which takes a maximal value corresponding to ω=1 defining the ordinary projective space P^(4).For generic values of ω,we show that the non BPS states are ***,we conduct a similar study of five-dimensional black *** the allowed magnetic charge regions of the BPS and non BPS black stringy solutions derived from M5-branes on dual divisors,we calculate the tension taking a minimal value for P^(4).By determining the recombination factor,we show that the non-BPS black string states are stable in the allowed regions in the magnetic charge space.

关键词： M-theory Calabi-Yau manifolds black holes black strings stability behaviors

Advanced gastric cancer:Current treatment landscape and future perspectives

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World Journal of Gastroenterology 2016年第8期22卷 2403-2414页

作者： Antonia digklia Anna dorothea Wagner departement d’oncologie Centre Hospitalier Universitaire Vaudois

Gastric cancer currently ranks fourth in cancer-related mortality worldwide. In the western world, it is most often diagnosed at an advanced stage, after becoming metastatic at distant sites. Patients with advanced disease(locally advanced or metastatic) have a somber prognosis, with a median overall survival of 10-12 mo, and palliative chemotherapy is the mainstay of treatment. In recent years, novel approaches using inhibition of human epidermal growth factor receptor 2(HER2) have demonstrated significant improvements in progression-free and overall survival, compared with chemotherapy alone, in first-line treatment of patients with overexpression of HER2. In addition, both second-line chemotherapy and treatment with the vascular endothelial growth factor receptor-inhibitor ramucirumab demonstrated significant benefits in terms of overall survival, compared with best supportive care, in randomized studies. Moreover, ramucirumab in combination with chemotherapy demonstrated further significant benefits in terms of progression-free and overall survival, compared with chemotherapy alone, in second-line treatment for patients with metastatic gastric cancer. A recently published molecular classification of gastric cancer is expected to improve patient stratification and selection for clinical trials and provide a roadmap for future drug development. Nevertheless, despite these developments the prognosis of patients with advanced gastric cancer remains poor. In this review we discuss current standards of care and outline major topics of drug development in gastric cancer.

关键词： Gastric cancer Phase III Clinical trials Chemotherapy Targeted therapy Perspectives

Hyperprolactinemia in Hospitals in Lomé: diagnostic and Therapeutic Aspects

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Open Journal of Internal Medicine 2024年第1期14卷 43-52页

作者： Tchamdja Toyi djalogue Lihanimpo Kodjo Kossi Ganu Koudjo Kaaga Laconi Yéba Mossi Komi Edem M’bortché B. Kodjo djibril Mohaman Awalou Balaka Abago Internal Medicine departement University de Kara Kara Togo Internal Medicine departement Université of Lomé Lomé Togo

Introduction. Hyperprolactinemia represents a supraphysiological secretion of prolactin. In clinical practice, it is the most frequently encountered anterior pituitary disorder. However, its real prevalence is little known in Africa. The purpose of this study is to list all cases of hyperprolactinemia over the past four years and to make an inventory of the various etiologies found and their management. Methodology. This is a cross-sectional descriptive study on the files of patients who came for consultation in the internal medicine and endocrinology department with hyperprolactinemia retrospectively collected from January 2017 to december 2020. Included were patients followed or whose the diagnosis of hyperprolactinemia was established in endocrinological consultation during the study period. Results. This study recorded 26 cases of hyperprolactinemia. The female sex represented 73.08% (sex ratio M/F 0.37) and the average age was 33.92 years. The 40 - 50 age group was the most represented with 30.77%. In women, galactorrhea accounted for 73.07%, amenorrhea 57.69% of clinical pictures and infertility 23.08%. In men, infertility accounted for 7.69% of presentations, gynecomastia 11.54% and erectile dysfunction 15.38%. The duration of evolution of the signs was 4 months in 23.08% of the patients. The mean prolactinemia was 702.58 ng/ml. CT was performed in 80.85% of patients. The main etiologies were pituitary adenomas (77%). All our patients were treated with dopaminergic agonists. Cabergoline was prescribed in 77% of patients. The evolution was favorable in 96.25% of patients. Conclusion. Hyperprolactinemia is a pathology that exists in our regions. The main etiology remains pituitary adenomas and treatment with cabergoline.

关键词： Hyperprolactinemia Hospital Environment CHU SO Togo

Modelling of the variation of granular base materials resilient modulus with material characteristics and humidity conditions

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Journal of Road Engineering 2024年第1期4卷 27-35页

作者： Jean-Pascal Bilodeau Erdrick Leandro Perez-Gonzalez Ali Saeidi departement de Genie Civil et Genie des Eaux Universite LavalQuebecG1V 0A6Canada departement des Sciences Appliquees Universite du Quebeca ChicoutimiChicoutimiG7H 2B1Canada

This study aims to quantify the susceptibility of granular materials used in pavements to changes in moisture content and propose a correlation model to incorporate this susceptibility into seasonal *** fines content and the percentage of fractured coarse aggregates were identified as direct indicators of the resilient modulus susceptibility to changes in water *** results showed that the percentage of fractured coarse aggregates particles(FR)has a more significant impact on the resilient modulus(Er)of crushed granular materials used in pavement construction than the combined indicator of the fines content and sample volumetrics(nf).Crushed granular materials with a higher percentage of fractured coarse aggregates are relatively insensitive to changes in the degree of saturation,but become more sensitive as the fine fraction porosity *** adjusted model was proposed based on the existing formulation,but considers a complex parameter to describe and adjust the sensitivity of base granular materials to variations in moisture content with respect to fabrication charac-teristics,fines content and volumetric *** model shows that the variation of Er values is below10%for fully crushed granular ***,it reaches approximately±12%for materials with 75%of crushed coarse aggregates andþ40%and-25%for materials with FR=50%.This model could help select good ag-gregates characteristics and adjust grain-size distribution for environments where significant moisture content variations can occur in the pavement system,such as in the Province of Quebec(Canada).As it is based on pa-rameters that can be easily determined or estimated,it also represents a valuable tool for detailed design and analysis that can consider material characteristics.

关键词： Resilient modulus degree of saturation Humidity conditions Unbound granular materials Pavement base

Compliance with Oral Anti-diabetic Treatment in Lome

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Open Journal of Internal Medicine 2024年第1期14卷 53-63页

作者： Tchamdja Toyi djalogue Lihanimpo Kodjo Kossi Kaaga Laconi Yéba Mossi Komi Edem M’bortché B. Kodjo Ehon Ata Edem djibril Mohaman Awalou Balaka Abago Internal Medicine departement Université de Kara Kara Togo Internal Medicine departement Université de Lomé Lomé Togo

Objective: The objective of this study was to assess adherence to antidiabetic therapy in type II diabetic patients and factors associated with Lomé. Method: This was a descriptive observational study conducted among diabetics in diabetes care centers from May 1, 2020 to October 1, 2020, for a period of 6 months. Results: A total of 300 patients were questioned. The mean age was 56.61 years (standard deviation = 11.7). The sex ratio was 0.6. All the patients were on drug treatment, 83.4% of whom were on metformin and 37.5% on Glibenclamide. In 58.3% of the cases, the patients were on dual therapy and 96.2% had an abovenormal glycated hemoglobin value. There was a medication adherence problem with poor adherence in 30.7%. Being aged 50 and over (ORC = 1.78, p = 0.048), playing sports (ORR = 1.87, p = 0.046), have reaching a higher level of education (ORR = 5.78, p = 0.005) significantly increased the chances of patients having a good/minimal problem of adherence. Conclusion: diabetes affects in Togo, more women than men with a predominance of those aged 50 and over. Adherence to therapy remains a challenge.

关键词： Type II diabetes Metformin Compliance Associated Factors

The dual of the Two-Variable Exponent Amalgam Spaces (L^q(),l^p())(Ω)

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Journal of Applied Mathematics and Physics 2024年第2期12卷 383-431页

作者： Sambourou Massinanke Sékou Coulibaly Mamadou Traore departement d’Etudes et de Recherches de Mathématiques et d’Informatique Université des Sciences des Techniques et des Technolo-gies de Bamako Bamako Mali

Wiener amalgam spaces are a class of function spaces where the function’s local and global behavior can be easily distinguished. These spaces are ex-tensively used in Harmonic analysis that originated in the work of Wiener. In this paper: we first introduce a two-variable exponent amalgam space (Lq(),lp())(Ω). Secondly, we investigate some basic properties of these spaces, and finally, we study their dual.

关键词： Amalgam Spaces Variable Exponent Lebesgue Spaces dual of a Vector Space

Management of Testicular Cancers in Brazzaville

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Open Journal of Urology 2024年第5期14卷 324-332页

作者： Roland Bertile Banga-Mouss Yanick dimi Nyanga Brice Nkoua Epala Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Eliane Ndounga Alexis Bolenga Louis Constant Mbele Mantsouaka Judith Nsonde Malanda Aanani Séverin Wencesl Odzébé Prosper Alain Bouya departement of Urology and Andrology University Hospital of Brazzaville Brazzaville Republic of the Congo departement of Medicale Oncology and Radiotherapy University Hospital of Brazzaville Brazzaville Republic of the Congo

Introduction: Testicular cancer accounts for 5% of urological tumors, predominantly affecting young men. The aim of our study was to report the diagnostic and evolutionary aspects of testicular cancer cases treated in our center. Patients and Methods: A retrospective study conducted over a 15-year period involving 12 patients treated for testicular cancer at the University Hospital of Brazzaville. Results: The median age was 31 years (range 11 to 49 years), with a median consultation delay of 10.6 months (range 3 to 27 months). Scrotal mass was the most common reason for consultation. Cancer was bilateral in two patients. Two patients were admitted with metastatic disease. Histopathological examination favored germ cell tumors in 7 cases, two cases of non-Hodgkin’s malignant lymphoma, and one case of epididymo-testicular adenocarcinoma. Adjuvant chemotherapy resulted in complete remission in patients with germ cell tumors. However, neoadjuvant chemotherapy was not effective in patients admitted with advanced-stage disease. Conclusion: Testicular cancer is a rare condition that is curable in the majority of cases, but its management is often complicated in our setting due to delayed diagnosis caused by taboos surrounding genital organ pathologies.

关键词： Testicular Cancer Germ Cell Tumor Cisplatin Testicular Lymphoma Testicular Adenocarcinoma

Urological Emergencies at the University Hospital of Brazzaville: Epidemiological, Clinical, and Therapeutic Aspects

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Open Journal of Urology 2024年第5期14卷 333-345页

作者： Roland Bertile Banga-Mouss Yannick dimi Nyanga Irène Ondima Armel Melvin Atipo Ondongo Steve Aristide Ondziel-Opara Joseph Junior damba Nick Arnaud Monabeka Christ Ondzé daniella Gloire Ngassiele Gidmard Onguele Henock Songa Jetsvy Mayala Anani Wensels Severin Odzebe Prosper Alain Bouya departement of Urology and Andrology University Hospital of Brazzaville Brazzaville Republic of the Congo

Introduction: Urological emergencies play a significant role in the medical and surgical activity of a urology department. The objective of this study was to determine the hospital prevalence of urological emergencies at the University Hospital of Brazzaville (CHUB), identify the different pathologies requiring urgent care, and list the various therapeutic methods. Patients and methods: A retrospective study of patients admitted to the medical and surgical emergencies department of CHUB over a 5-year period. Patient records admitted and treated for a urological emergency were included. The variables studied were the frequency of urological emergencies, patient age at admission, gender, nature of the emergency, and various therapeutic options. Results: Urological emergencies accounted for 4.3% of all medical and surgical emergencies. The mean age was 57 ± 28 years with a range of 3 to 93 years. The male-to-female ratio was 7.1. The most common conditions were urinary retention (54.67%), hematuria (17.20%), and renal colic (8.13%). Therapeutically, surgical urinary drainage was dominated by cystostomy. Conclusion: Urological emergencies are infrequent at the University Hospital of Brazzaville. Their management is often delayed.

关键词： Urological Emergencies Urinary Retention Hematuria Renal Colic