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Journal of Rare earths 2024年第10期42卷 1950-1959页

作者： P.A.Martínez-Montoya J.M.del Río A.de J.Morales-Ramirez M.Corea escuela Superior de Ingeniería Química e Industrias extractivas ESIQIE-IPNDepartamento de Ingeniería Metalúrgica UPALM S/N Col.Lindavista escuela Superior de ingenieria Química e Industrias extractivas ESIQIE-IPNLaboratorio de Investigación en Polímeros y NanomaterialesUPALM S/N Col.Lindavista Centra de Investigación e Innovación Tecnológica CIITEC-IPNCda.de CECATIs/n

Polymeric nanoparticles of poly(methyl methacrylate) were obtained by emulsion polymerization techniques in a proce ss of two *** particles were functionalized with acrylic acid,curcumin,and fumaramide and three series of polymeric particles were *** incorporation of functional groups was confirmed by Fourier transform-infrared spectrosocopy(FT-IR) and ultraviolet-visible(UV-Vis) *** spherical morphology of particles with an average diameter of 100 nm was observed by scartning electron microscopy(SeM).The polymeric materials were used for recovery of [eu]from synthetic *** nanoparticles show excellent chelation capacity to trap rare-earth ions,because they recover more than 85% of [eu] at pH of *** images of SeM after extraction process show arrays between particles with larger average particle sizes to 1.5 *** addition,the particles have a good stripping capacity,exceeding 50% of it,maintaining their homogeneity in morphology and good stability in dispersion for the recovery and stripping processes.A pseudo-second model order is obtained for the extraction and stripping processes while the best results of stripping process are obtained at pH of6.

关键词： Chelating effect emulsion polymerization extraction process Rare earths Stripping process [eu]recovery

Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats withα-synucleinopathy

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Neural Regeneration Research 2024年第9期19卷 2057-2067页

作者： Bismark Gatica-Garcia Michael J.Bannon Irma Alicia Martínez-Dávila Luis O.Soto-Rojas David Reyes-Corona Lourdes escobedo Minerva Maldonado-Berny Me Gutierrez-Castillo Armando J.espadas-Alvarez Manuel A.Fernandez-Parrilla Juan U.Mascotte-Cruz CP Rodríguez-Oviedo Irais e.Valenzuela-Arzeta Claudia Luna-Herrera Francisco e.Lopez-Salas Jaime Santoyo-Salazar Daniel Martinez-Fong departamento de Fisiología Biofísica y NeurocienciasCentro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico department of Pharmacology Wayne State University School of MedicineDetroitMIUSA Laboratorio de Patogénesis Molecular Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Red de Medicina para la educación y desarrollo y la Investigación Científica de Iztacala(Red MeDICI) Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Nanoparticle Therapy Institute AguascalientesMéxico departamento de Biociencias e Ingeniería Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de MéxicoMéxico escuela Nacional de Medicina y Homeopatía Instituto Politécnico NacionalCiudad de MéxicoMéxico departamento de Fisiología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalCiudad de MéxicoMéxico departamento de Biología Molecular y Biotecnología Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico departamento de Física Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Programa de Nanociencias y Nanotecnología Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico

Parkinsonism by unilateral,intranigralβ-sitosterolβ-D-glucoside administration in rats is distinguished in that theα-synuclein insult begins unilaterally but spreads bilaterally and increases in severity over time,thus replicating several clinical features of Parkinson’s disease,a typicalα-*** Nurr1 repressesα-synuclein,we evaluated whether unilateral transfected of rNurr1-V5 transgene via neurotensin-polyplex to the substantia nigra on day 30 after unilateralβ-sitosterolβ-D-glucoside lesion could affect bilateral neuropathology and sensorimotor deficits on day 30 *** study found that rNurr1-V5 expression but not that of the green fluorescent protein(the negative control)reducedβ-sitosterolβ-D-glucoside-induced ***,a bilateral increase in tyrosine hydroxylase-positive cells and arborization occurred in the substantia nigra and increased tyrosine hydroxylase-positive ramifications in the *** addition,tyrosine hydroxylase-positive cells displayed less senescence markerβ-galactosidase and more neuron-cytoskeleton markerβIII-tubulin and brain-derived neurotrophic factor.A significant decrease in activated microglia(positive to ionized calcium-binding adaptor molecule 1)and neurotoxic astrocytes(positive to glial fibrillary acidic protein and complement component 3)and increased neurotrophic astrocytes(positive to glial fibrillary acidic protein and S100 calcium-binding protein A10)also occurred in the substantia *** effects followed the bilateral reduction inα-synuclein aggregates in the nigrostriatal system,improving sensorimotor *** results show that unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neurodegeneration(senescence and loss of neuron-cytoskeleton and tyrosine hydroxylase-positive cells),neuroinflammation(activated microglia,neurotoxic astrocytes),α-synuclein aggregation,and sensorimotor *** neurotrophic astrocytes and

关键词： A1 astrocytes A2 astrocytes gene therapy microglia motor deficits nanoparticles neurodegeneration neuroinflammation senescence α-synuclein aggregates

The effect of Water and Salt Stress on Paspalum dilatatum,a Constituent of Pampas Natural Grasslands

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Phyton-International Journal of experimental Botany 2024年第8期93卷 2009-2018页

作者： Claudia A.Porcelli Gerardo Rubio Flavio H.Gutiérrez Boem Raul S.Lavado departamento de Química Facultad de AgronomíaUniversidad de Buenos AiresBuenos AiresC1417DSEArgentina Instituto de investigaciones en Biociencias Agricolas y Ambientales(INBA) Facultad de AgronomíaUniversidad de Buenos AiresBuenos AiresC1417DSEArgentina

The effects of the salt stress on plant growth are usually increased by the water *** studied the impact of both stresses in simultaneous pulses of drought and salinity on Paspalum *** forage species is native to South America,spread in grasslands in many tropical,subtropical,and temperate areas of the world,and very common in grasslands of the Flooding Pampas of *** what happens in *** compared a pot experiment,a non-stressed control against water stress for a month(midpoint between field capacity and wilting point),and two saline stresses(moderate,6 d·Sm^(−1)and strong,12 d·Sm^(−1)),also for a *** biomass(green leaf;non-leaf green material,and dry material)and roots were harvested,weighed,and analyzed for nitrogen,phosphorus,and *** biomass of all components significantly decreased when both stresses were *** plus strong saline stress reduced by half the total biomasses,compared to the *** proportion of aerial biomass/root biomass ratio as well as aerial green component/dry materials ratio tend to decrease when subjected to both *** concentration in plants was not significantly affected,but phosphorus concentration increased in aerial biomass components,from 0.10 to 0.18 mg·kg^(−1)between the extreme treatments,but did not change in *** concentration in plants increased(i.e.,in green leave sodium(Na)increased from 0.27 to 2.01 mg·kg^(−1)between the extreme treatments),whereas other cations either did not change or decreased,affecting the ratios between *** performance allows us to infer that the Na accumulation of *** behaves in an intermediate range,compared to very tolerant to salts or non-salt tolerant species of the Paspalum *** agreement,when salts were applied in the form of a pulse,*** tolerated higher salinity than that found by other authors for the same species,using continuous salinity.

关键词： Dallis grass salinity drought sodium in plants phosphorus in plants potassium/sodium ratio

Influence of Pipe-Diameter on Water Hammer Phenomenon

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Journal of Mechanics engineering and Automation 2015年第6期5卷 370-376页

作者： Provenzano Pablo Gabriel departamento de ingenieria e investigaciones teenol6gicas Universidad Naeional de La Matanza San Justo (C.P. 1744) Provinciade Buenos Aires Argentina

The influence of parameters pertaining to the confinant structure on water hammer had been less studied than those relative to the fluid. One of them is the inner pipe-diameter, a basic structural-parameter that makes its influence in essential hydraulic topics such as head loss, in pipelines. In this paper, the objective is to analyze the inner-diameter influence on water hammer phenomenon. An analytical algorithm for solving the unsteady-one-dimensional water hammer model had been applied. It had allowed estimating the instantaneous head at any point of a single pipeline. The model was solved by mean of the Laplace＇s Transformed application and the anti-transforming procedure into the complex field. To determinate the influence of internal-diameter conduit on the pressure oscillation, four distinct inside-diameter values were introduced into the solution, successively. The first overpressure-peak at each case was tabulated along with the corresponding inner^liameter and a mathematical relation had been founded. The obtained results show a close dependence between both, over-pressure peaks and internal-pipe diameter. It was founded that this dependence is given in terms of a non-linear relation between them. It was further founded that the wave frequency is sensitive to the variation of the pipe-diameter.

关键词： Transient overpressure shear stress radial.

Fault diagnosis of spur gearbox based on random forest and wavelet packet decomposition

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Frontiers of Mechanical engineering 2015年第3期10卷 277-286页

作者： Diego CABReRA Fernando SANCHO Rene-Vinicio SANCHeZ Grover ZURITA Mariela CeRRADA Chuan LI Rafael e. VASQUeZ departamento de ingenieria Mecainica Universidad Politecnica Salesiana Cuenca Ecuador departamento de Ciencias de la Computaci6n e Inteligencia Artificial Universidad de Sevilla Espafia departamento de ingenieria electro-Mechnica Universidad PrivadaBoliviana Cochabamba Bolivia departamento de Sistemas de Control Universidad de Los AndesM6rida Venezuela Research Center of System Health Maintenance Chongqing Technologyand Business University Chongqing 400067 China Facultad de ingenieria Mecainica Universidad Pontificia BolivarianaMedellln Colombia

This paper addresses the development of a random forest classifier for the muki-class fault diagnosis in spur gearboxes. The vibration signal＇s condition parameters are first extracted by applying the wavelet packet decomposition with multiple mother wavelets, and the coefficients＇ energy content for terminal nodes is used as the input feature for the classification problem. Then, a study through the parameters＇ space to find the best values for the number of trees and the number of random features is performed. In this way, the best set of mother wavelets for the application is identified and the best features are selected through the internal ranking of the random forest classifier. The results show that the proposed method reached 98.68% in classification accuracy, and high efficiency and robustness in the models.

关键词： fault diagnosis spur gearbox wavelet packet decomposition random forest

Antifeedant Activity of Caesalpinia coriaria essential Oil Against Incisitermes marginipennis (Latreille)

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Phyton-International Journal of experimental Botany 2021年第3期90卷 907-920页

作者： Cesar B.Ramírez-López Rita Beltrán-Sánchez Alistair Hernández-Izquierdo JoséLuis Salvador-Hernández eduardo Salcedo-Pérez Rosa e.del Río Mauro M.Martínez Pacheco Instituto de investigaciones Químico Biológicas Universidad Michoacana de San Nicolás de HidalgoMorelia58030Mexico departamento de Botánica y Zoología CUCBA Universidad de GuadalajaraNextipac45200Mexico

This study scrutinized the possibility of finding toxicant or deterrent plant metabolites against the dry wood termite Incisitermes marginipennis(Latreille).Plant deterrent agents act as repellents or antifeedants to prevent wood decay and increase its useful *** potential of the tree Caesalpinia coriaria(Fabaceae)as a biological source of molecules with deterrent effects against the dry wood termite was assessed by a phytochemical fractionation guided by repellence and antifeedant *** gas chromatography-mass spectrometry analysis of the leaf essential oil showed geraniol to be one of the major components and its repellent and antifeedant effects were *** had only an antifeedant effect without affecting the body weight or survival of the dry wood *** the leaf essential oil,geraniol did not exhibit a repellency *** in-silico approach of the activity of acetylcholinesterase in interaction with geraniol resulted in an affinity energy of−7.5 Kcal/*** interacted with the amino acid tyrosine 324 located in the enzyme’s active site while citronellol(negative control)interacted with tryptophan 83 located adjacent to the active *** deterring terpenes have not been implemented for the preservation and restoration of wood products exposed to the attack of the dry wood ***,they are an important natural control alternative.

关键词： Termite geraniol repellent antifeedant deterrent

Insights into the effect of a Natural Arsenate Dose on Growth,Nodulation and Redox Metabolism of Soybean Plants

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Pedosphere 2019年第4期29卷 527-533页

作者： eliana BIANUCCI Ana FURLAN Luis e.HeRNáNdeZ Stella CASTRO Instituto de investigaciones Agrobiotecnológicas INIAB CONICET-UNRC Facultad de Ciencias ExactasFísico-Químicas y Naturales Universidad Nacional de Río Cuarto Laboratorio de Fisiología Vegetal Departamento de BiologíaUniversidad Autónoma de Madrid

dear editor, Arsenic (As) is a harmful metalloid that occurs in soil and water;its concentration varies considerably among geographic regions, with groundwater being the principal source of human contamination (Smedley and Kinniburgh, 2002). Besides the direct contamination effect of drinking water that contains high As concentration, human poisoning may also occur after ingestion of contaminated food.

关键词： Natural Arsenate Soybean Plants Redox Metabolism

effects of chlorpyrifos on enzymatic systems of Cydia pomonella （Lepidoptera： Tortricidae） adults

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Insect Science 2017年第3期24卷 455-466页

作者： Laura Beatriz Parra Morales Raul Adolfo Alzogaray Liliana Cichon Silvina Garrido Jimena Soleno Cristina Monica Montagna Laboratorio de investigaciones Bioquimicas Quimicas y de Medio Ambiente Facultad de Ingenieria Universidad Nacional del ComahueBuenos Aires 1400 (Q83001BX) Neuquen Facultad de Ciencias del Ambiente y la Salud Universidad Nacional del Comahue Buenos Aires 1400 Neuquen Centro de investigaciones de Plagas e Insecticidas (CIPeIN-UNIdeFICONICeT) Villa Martelli Buenos Aires Instituto de Investigacion e ingenieria Ambiental (3iA-UNSAM) San Martin Provincia de Buenos Aires Instituto Nacional de Tecnologia Agropecuaria Estacion Experimental Alto Valle General Roca Argentina

The control program of codling moth （Cydia pomonella L.） in the Rio Negro and Neuqu6n Valley is intended to neonate larvae. However, adults may be subjected to sublethal pesticide concentrations generating stress which might enhance both mutation rates and activity of the detoxification system. This study assessed the exposure effects of chlorpyrifos on target enzyme and, both detoxifying and antioxidant systems of surviving adults from both a laboratory susceptible strain （LSS） and a field population （FP）. The results showed that the FP was as susceptible to chlorpyrifos as the LSS and, both exhibited a similar chlorpyrifos-inhibitory concentration 50 （IC50） of acetylcholinesterase （ACHe）. The FP displayed higher carboxylesterase （Care） and 7-ethoxycoumarine O-deethylase （eCOD） activities than LSS. Both LSS and FP showed an increase on Care activity after the exposure to low-chlorpyrifos concentrations, followed by enzyme inhibition at higher concentrations. There were no significant differences neither in the activities of glutathione S-transferases （GST）, catalase （CAT） and superoxide dismutase （SOD） nor in the reduced glutathione （GSH） content between LSS and FP. Moreover, these enzymes were unaffected by chlorpyrifos. In conclusion, control adults from the FP exhibited higher Care and eCOD activities than control adults from the LSS. AChe and Care activities were the most affected by chlorpyrifos. Control strategies used for C. pomonella, such as rotations of insecticides with different modes of action, will probably delay the evolution of insecticide resistance in FPs from the study area.

关键词： acetylcholinesterase antioxidant system chlorpyrifos codling moth detoxification enzymes

The detrimental effects of lipopolysaccharideinduced neuroinflammation on adult hippocampal neurogenesis depend on the duration of the pro-inflammatory response

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Neural Regeneration Research 2019年第5期14卷 817-825页

作者： Martha Pérez-Domínguez evangelina ávila-Mu?oz eduardo Domínguez-Rivas Angélica Zepeda departamento de Medicina Genómica y Toxicología Ambiental Instituto de Investigaciones Biomédicas.Universidad Nacional Autónoma de MéxicoCDMX

Adult hippocampal neurogenesis is a finely tuned process regulated by extrinsic factors. Neuroinflammation is a hallmark of several pathological conditions underlying dysregulation of neurogenesis. In animal models, lipopolysaccharide(LPS)-induced neuroinflammation leads to a neurogenic decrease mainly associated to the early inflammatory response. However, it is not well understood how the neuroinflammatory response progresses over time and if neurogenesis continues to be diminished during the late neuroinflammatory response. Moreover, it is unknown if repeated intermittent administration of LPS along time induces a greater reduction in neurogenesis. We administered one single intraperitoneal injection of LPS or saline or four repeated injections(one per week) of LPS or saline to young-adult mice. A cohort of new cells was labeled with three 5-bromo-2-deoxyuridine injections(one per day) 4 days after the last LPS injection. We evaluated systemic and neuroinflammation-associated parameters and compared the effects of the late neuroinflammatory response on neurogenesis induced by each protocol. Our results show that 1) a single LPS injection leads to a late pro-inflammatory response characterized by microglial activation, moderate astrocytic reaction and increased interleukin-6 levels. This response correlates in time with decreased neurogenesis and 2) a repeated intermittent injection of LPS does not elicit a late pro-inflammatory response although activated microglia persists. The latter profile is not accompanied by a continued longterm hippocampal neurogenic decrease. Hereby, we provide evidence that the neuroinflammatory response is a dynamic process that progresses in a milieu-dependent manner and does not necessarily lead to a neurogenic decrease, highlighting the complex interaction between the immune system and neurogenesis.

关键词： dentate gyrus subgranular zone inflammation microglia astrocytes IL-6 cytokines cell proliferation neural progenitor cells immature neurons long-term short-term adult hippocampal neurogenesis

Reiterated homogenization of a laminate with imperfect contact:gain-enhancement of effective properties

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Applied Mathematics and Mechanics(english edition) 2018年第8期39卷 1119-1146页

作者： F.e.ALVAReZ-BORGeS J.BRAVO-CASTILLeRO M.e.CRUZ R.GUINOVART-DIAZ L.D.PeReZ-FeRNANdeZ R.RODRIGUeZ-RAMOS F.J.SABINA Facultad de Matematica y Computacion Departamento de MatematicaUniversidad de La HabanaSan Lazaro y LHabana 4La HabanaCP 10400Cuba departamento de Matematicas y Mecanica Universidad Nacional Autonoma de MexicoInstituto de Investigaciones en Matematicas Aplicadas y en Sistemas01000 CDMXAP 20-126M′exico departamento de engenharia Mecanica Universidade Federal do Rio de JaneiroPolitecnica/COPPECaixa Postal 68503Rio de JaneiroRJCEP 21941-972Brasil departamento de Matematica e estatistica Universidade Federal de PelotasCaixa Postal 354PelotasRio Grande do SulCEP 96010-900Brasil

A family of one-dimensional(1D) elliptic boundary-value problems with periodic and rapidly-oscillating piecewise-smooth coefficients is considered. The coefficients depend on the local or fast variables corresponding to two different structural scales. A finite number of imperfect contact conditions are analyzed at each of the scales. The reiterated homogenization method(RHM) is used to construct a formal asymptotic solution. The homogenized problem, the local problems, and the corresponding effective coefficients are obtained. A variational formulation is derived to obtain an estimate to prove the proximity between the solutions of the original problem and the homogenized problem. Numerical computations are used to illustrate both the convergence of the solutions and the gain of the effective properties of a three-scale heterogeneous 1D laminate with respect to their two-scale counterparts. The theoretical and practical ideas exposed here could be used to mathematically model multidimensional problems involving multiscale composite materials with imperfect contact at the interfaces.

关键词： reiterated homogenization method(RHM) imperfect contact variational formulation effective coefficient gain