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from partial to complete:Wing-and tail-feather moult sequence and intensity depend on species,life-cycle stage,and moult completeness in passerines

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Avian Research 2024年第1期15卷 98-107页

作者： Santi Guallar departament de Vertebrats Museu de Ciencies Naturals de BarcelonaBarcelona08003Spain

Passerines moult during various life-cycle stages.Some of these moults involve the retention of a variable quantity of wing and tail feathers.This prompts the question whether these partial moults are just arrested complete moults or follow different processes.To address it,I investigated whether three relevant features remain constant across partial and complete moults:1) moult sequence(order of activation) within feather tracts(e.g.,consecutive outward moult of primaries) and among tracts(e.g.,starting with marginal coverts,followed by greater coverts second,tertials,etc.);2) dynamics of moult intensity(amount of feathers growing along the moult progress);and 3) protection of wing quills by overlapping fully grown feathers.To study the effect of moult completeness on these three features,I classified moults of 435 individuals from 61 species in 3 groups:i) complete and partial,ii) without and iii) with retention of feathers within tracts.To study the effect of life-cycle stage,I used postbreeding,postjuvenile,and prebreeding moults.I calculated phylogenetically corrected means to establish feather-moult sequence within tracts.I applied linear regression to analyse moult sequence among tracts,and polynomial regression to study the dynamics of moult intensity as moult progresses.Sequence and intensity dynamics of partial moults tended resemble those of the complete moult as moult completeness increased.Sequence within and among feather tracts tended to shift as moult intensity within tracts and number of tracts increased.Activation of primaries advanced in relation to the other feather tracts as number of moulted primaries increased.Tertial quills were protected by the innermost greater covert regardless of moult completeness.These findings suggest that moult is a self-organised process that adjusts to the degree of completeness of plumage renewal.However,protection of quills and differences among species and between postjuvenile-and prebreeding-moult sequences also suggest an active control linked to feather fun

关键词： Mass-gap index Moult extent Moult regulation Polynomial regression

Solution of the Center Problem for a Class of Polynomial Differential Systems

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Acta Mathematica Sinica,English Series 2024年第7期40卷 1685-1696页

作者： Chang Jian LIU Jaume LLIBRE Rafael RAMíREZ Valentín RAMíREZ School of Mathematics (Zhuhai) Sun Yat-sen University departament de Matemàtiques Universitat Autònoma de Barcelona departament d'Enginyeria Informàtica i Matemàtiques Universitat Rovira i Virgili

Consider the polynomial differential system of degree m of the form ■ where μ and ν are real numbers such that（μ2+ ν2）(μ + ν（m-2）)（a1～2+ a2～2） ≠0, m > 2 and Ωm-1（x, y） is a homogenous polynomial of degree m-1. A conjecture, stated in J. Differential Equations 2019,suggests that when ν = 1, this differential system has a weak center at the origin if and only if after a convenient linear change of variable（x, y） →（X, Y） the system is invariant under the transformation（X, Y, t） →（-X, Y,-t）. for every degree m we prove the extension of this conjecture to any value of ν except for a finite set of values of μ.

关键词： Center problem polynomial differential system 34C07 34C20

5-Bromo-2'-deoxyuridine labeling:historical perspectives,factors infiuencing the detection,toxicity,and its implications in the neurogenesis

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Neural Regeneration Research 2024年第2期19卷 302-308页

作者： Joaquín Martí-Clúa Unidad de Citología e Histología.departament de Biologia Cel·lular de Fisiologia i d’Immunologia.Facultad de Biociencias.Institut de Neurociències.Universidad Autónoma de Barcelona08193 BellaterraBarcelonaSpain

The halopyrimidine 5-bromo-2′-deoxyuridine(BrdU)is an exogenous marker of DNA synthesis.Since the introduction of monoclonal antibodies against BrdU,an increasing number of methodologies have been used for the immunodetection of this synthesized bromine-tagged base analogue into replicating DNA.BrdU labeling is widely used for identifying neuron precursors and following their fate during the embryonic,perinatal,and adult neurogenesis in a variety of vertebrate species including birds,reptiles,and mammals.Due to BrdU toxicity,its incorporation into replicating DNA presents adverse consequences on the generation,survival,and settled patterns of cells.This may lead to false results and misinterpretation in the identification of proliferative neuroblasts.In this review,I will indicate the detrimental effects of this nucleoside during the development of the central nervous system,as well as the reliability of BrdU labeling to detect proliferating neuroblasts.Moreover,it will show factors influencing BrdU immunodetection and the contribution of this nucleoside to the study of prenatal,perinatal,and adult neurogenesis.Human adult neurogenesis will also be discussed.It is my hope that this review serves as a reference for those researchers who focused on detecting cells that are in the synthetic phase of the cell cycle.

关键词： 5-bromo-2′-deoxyuridine adult neurogenesis human adult neurogenesis labeling pitfalls prenatal neurogenesis proliferation S-phase suturing S-phase toxicity

Protein glycation:a wolf in sweet sheep’s clothing behind neurodegeneration

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Neural Regeneration Research 2024年第5期19卷 975-976页

作者： Ana B.Uceda francisco Leal-Pérez Miquel Adrover Institut Universitari d’Investigacióen Ciències de la Salut(IUNICS) Institut d’InvestigacióSanitària Illes Balears(IdISBa) departament de Química Universitat de les Illes BalearsCtraPalma de MallorcaSpain

At the beginning of the 16th century,Paracelsus coined the maxim:“the dose makes the poison”.This principle can be applied to all living organisms,including organs and cells.The brain and its glial and neuronal cells are no exception.Even small compounds that are essential for the life of brain cells can become truly toxic when overdosed.

关键词： organs sheep sweet

design and redesign journey of a drug for transthyretin amyloidosis

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Neural Regeneration Research 2025年第4期20卷 1096-1097页

作者： francisca Pinheiro Salvador Ventura Institut de Biotecnologia i Biomedicina Departament de Bioquímica i Biologia MolecularUniversitat Autònoma de BarcelonaBellaterraSpain

The misfolding and subsequent aggregation of proteins into amyloid fibrils underlie the onset of a variety of human disorders collectively known as amyloidosis.Transthyretin(TTR)is one of the>30 amyloidogenic proteins identified to date and is associated with a group of highly debilitating and life-threatening disorders called TTR amyloidosis(ATTR).ATTR comprises senile systemic amyloidosis,which is linked to wild-type(WT)TTR aggregation,and hereditary ATTR,a dominantly inherited disorder caused by the deposition of one of over 130 TTR genetic variants.Senile systemic amyloidosis is a prevalent age-related amyloidosis,affecting up to 25%of the population over 80 years of age,and is characterized by the build-up of TTR fibrils in the myocardium.Regarding hereditary ATTR,the clinical presentation is highly heterogeneous,primarily affecting the peripheral nervous system(familial amyloid polyneuropathy-fAP)or the heart(familial amyloid cardiomyopathy).In rare cases,aggregation develops in the central nervous system,giving rise to a phenotype known as familial leptomeningeal amyloidosis(Carroll et al.,2022).

关键词： amyloid aggregation senile

Area Operators on Bergman Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1161-1176页

作者： Xiao fen LV Jordi PAU Mao fa WANG department of Mathematics Huzhou UniversityHuzhou 313000P.R.China departament de Matemàtiques i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain School of Mathematics and Statistics Wuhan UniversityWuhan 430072P.R.China

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0for the case n=1,some partial results were previously obtained by Wu in[Wu,Z.:Volterra operator,area integral and Carleson measures,Sci.China Math.,54,2487–2500(2011)].Especially,in the case qfor the area operators to be bounded.We solve the cases left open there and extend the results to n-complex dimension.

关键词： Area operator Bergman space tent space area formula

Refractive outcomes after V4c Toric collamer lens implantation over 1y of follow-up

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1322-1330页

作者： Humberto Carreras-Díaz Josefina Reñones de Abajo María del Rosario Carreras-Díaz Amalia Lorente-Velázquez Vithas Eurocanarias Las Palmas de Gran Canaria 35004Spain University Hospital of Girona Doctor Josep Trueta Gerona 17007Spain departament of Optometry and Vision Faculty of Optics and OptometryComplutense University of MadridMadrid 28040Spain

AIM:To evaluate refractive outcomes and corneal astigmatism changes after Toric implantable collamer lens with a central port(V4c T-ICL)implantation over 1y of follow-up.METHODS:A retrospective study was performed including 50 eyes of 50 patients that underwent V4c T-ICL implantation.Uncorrected(UDVA)and corrected(CDVA)distance visual acuities,refraction,refractive and corneal astigmatism changes and corneal coupling correction were evaluated preoperatively,1 and 12mo postoperatively.Vector analysis was used for astigmatism changes.Coefficient of adjustment(CAdj)was calculated for corneal coupling analysis.RESULTS:The mean UDVA achieved was 0.03 logMAR at 1mo and remained unchanged throughout the whole follow-up(P=0.193).At the last visit,84%of the eyes achieved a CDVA of 0.00 logMAR or better.Regarding spherical equivalent refraction(SEQ),96%of eyes were ranges of±1.00 D and 84%of them within±0.50 D.Also,94%of eyes had a remaining refractive cylinder within±1.00 D and 78%of them within±0.50 D.Both,SEQ and refractive cylinder,remain stable over the postoperative follow-up(P=1.000 and P=0.660,respectively).In terms of surgically induced astigmatism(SIA),no statistically significant differences were found over the follow-up(P=0.102)and under correction was found with a correction index lower than the unit at each visit.A keratometric astigmatism induced of 0.59±0.53(vector mean:0.26×73º)D was reached at the last visit.No significant changes in terms of corneal astigmatism orientation were reported over post-surgery visits(P=0.129 and P=0.097 at 1 and 12mo respectively).No clinical significance was found for CAdj on with-the-rule astigmatism.No postoperative complications resulting from the surgery were found.CONCLUSION:Refractive outcomes suggest that the V4c T-ICL implantation for correction of myopic astigmatism was satisfactory in terms of effectiveness,safety,and stability during 1y of follow-up.Corneal astigmatism induced by the incision around 0.5 D is achieved according to the remaining refractive cylinder f

关键词： V4c Toric collamer lens corneal astigmatism surgically induced astigmatism corneal coupling

Solar hydrogen production from electrochemical ammonia splitting powered by a single perovskite solar cell

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Journal of Energy Chemistry 2024年第5期92卷 292-295页

作者： Anna MBeiler Wenhui Li Alisa denisiuk Emilio Palomares Antoni Llobet Institute of Chemical Research of Catalonia(ICIQ).Barcelona Institute of Science and Technology(BIST) 43007 TarragonaSpain Catalan Institution for Research and Advanced Studies(ICREA) 08010 BarcelonaSpain departament de Química Universitat Autònoma de BarcelonaCerdanyola del Vallès08193 BarcelonaSpain

for carbon-free electrochemical fuel formation,the electrochemical cell must be powered by renewable energy.Obtaining solar-powered H_(2) fuel from water typically requires multiple photovoltaic cells and/or junctions to drive the water splitting reaction.Because of the lower thermodynamic requirements to oxidize ammonia compared to water,solar cells with smaller open circuit voltages can provide the required potential for ammonia splitting.In this work,a single perovskite solar cell with an open-circuit potential of 1.08 V is coupled to a 2-electrode electrochemical cell employing hybrid electroanodes functionalized with Ru-based molecular catalysts.The device is active for more than 30 min,producing N_(2) and H_(2) in a 1:2.9 ratio with 89%faradaic efficiency with no external applied bias.This work illustrates that hydrogen production from ammonia can be driven by conventional semiconductors.

关键词： Ammonia oxidation Redox catalysis Perovskites Solarfuels Transitionmetal complexes

A stable anthraquinone-derivative cathode to develop sodium metal batteries: The role of ammoniates as electrolytes

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Journal of Energy Chemistry 2023年第2期77卷 572-580,I0015页

作者： Débora Ruiz-Martínez José M.Orts Roberto Gómez departament de Química física i Institut Universitari d’Electroquímica Universitat d’AlacantApartat 99Alicante E-03080Spain

Rechargeable sodium metal batteries constitute a cost-effective option for energy storage although sodium shows some drawbacks in terms of reactivity with organic solvents and dendritic growth.Here we demonstrate that an organic dye,indanthrone blue,behaves as an efficient cathode material for the development of secondary sodium metal batteries when combined with novel inorganic electrolytes.These electrolytes are ammonia solvates,known as liquid ammoniates,which can be formulated as NaI·3.3NH_(3) and NaBf_(4)·2.5NH_(3).They impart excellent stability to sodium metal,and they favor sodium non-dendritic growth linked to their exceedingly high sodium ion concentration.This advantage is complemented by a high specific conductivity.The battery described here can last hundreds of cycles at 10 C while keeping a Coulombic efficiency of 99%from the first cycle.Because of the high capacity of the cathode and the superior physicochemical properties of the electrolytes,the battery can reach a specific energy value as high as 210 W h kgIB^(-1),and a high specific power of 2.2 kW kgIB^(-1),even at below room temperature(4℃).Importantly,the battery is based on abundant and cost-effective materials,bearing promise for its application in large-scale energy storage.

关键词： Sodium metal batteries Anthraquinone-based cathode Vat dye Indanthrone blue Inorganic electrolytes Liquid ammoniates