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What Do Employers Want? Views of Chinese and Canadian Job Seekers

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China & World Economy 2006年第6期14卷 107-120页

作者： M.W. Luke Chan James H. Tiessen Associate Professor School of Management University of Science and Technology Beijing China. Email: sunying@*** Professor Michael G. DeGroote School of Business McMaster University Canada. Email: chanmwl@mcmaster.ca Associate Professor Michael G. DeGroote School of Business McMaster University Canada. Email: tiessenj@mcmaster.ca.

Rapid globalization has led to many studies of cross-cultural issues and their implications for management. As China＇s importance in the international economy rises, the level of international business cooperation continues to increase. This paper first identifies differences in the cultural orientations of Chinese and Canadians entering the job market and then examines how these orientations are related to their perceptions of the criteria employers use when hiring. The analyses show that the cultural differences are not consistent with Hofstede＇s previous work. Further, there are significant differences in the qualities that are considered important when seeking a job. The results of this study increase mutual understanding and improve business relationships between the two countries.

关键词： Canada China cultural difference job selection criteria business student

Survey： Use of Acupuncture for the Treatment of Acute Low Back Pain by Physicians and Physiotherapists in Ontario

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Journal of Acupuncture and Tuina Science 2010年第6期8卷 331-335页

作者： Kien Vinh Trinh Alice Sy degroote school of medicine Office of MD Admissions McMaster University Ontario L8N 3Z5 Canada Faculty of Health Sciences McMaster University Ontario L8N 3Z5 Canada

Objective： To determine the prevalence of the use of acupuncture treatment for acute low back pain （LBP） among acupuncture practitioners, and investigate acupuncture practitioners＇ perceptions on the effectiveness of this treatment modality and the costs associated with its use in Canada. Methods： A questionnaire designed to achieve our objectives was distributed to all 285 members in the Ontario chapter of the Acupuncture Foundation of Canada （AFC） in September of 1996. Only responses from physicians and physiotherapists were included in the analysis. Results： Of the 281 eligible physicians and physiotherapists, 197 completed the survey （response rate of 70.1%）. 45.0% of the respondents were physicians and 55.0% of them were physiotherapists. 87.0% of the respondents had used acupuncture for the treatment of acute LBP in the past, 66.0% of them were using it at the time of the survey and 87.0% said they would continue to use it in the future. 83.0% of the respondents perceived acupuncture to be effective for acute LBP and 60.0% of them believed that treating acute LBP with acupuncture will prevent the development of chronic LBE The average cost per treatment was $28 and the average time of treatments thought to be necessary to treat acute LBP was 5.7. Conclusions： The results showed that the majority of the respondents had a positive and favorable outlook towards using acupuncture for the treatment of acute LBP. They frequently used acupuncture for treating this condition in their practice and an overwhelming majority perceived acupuncture to be effective for treating acute LBP. In addition, over half of the respondents believed that acupuncture treatment would prevent the progression of acute LBE Although the acupuncture practitioners surveyed in this study perceived acupuncture to be an effective treatment for acute LBP, quantitative data from high quality research are needed to validate these perceptions.

关键词： Low Back Pain: Acuouncture Theranv: Ouestionnaires

IL-25 and IL-25 receptor expression on eosinophils from subjects with allergic asthma

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IL-25 and IL-25 receptor expression on eosinophils from subj...

The mechanisms of sorafenib resistance in hepatocellular carcinoma:theoretical basis and therapeutic aspects

中华医学会呼吸病学年会——2013（第十四次全国呼吸病学学术会议）

作者： WEI TANG Steven Smith Sue Beaudin Benny Dua Karen Howie Gail Gauveaur Paul OByrne Firestone Institute of Respiratory Health Michael G DeGroote School of MedicineMcMaster UniversityHamiltonOntarioCanada. Department of Respirology Ruijin HospitalShanghai Jiaotong University School of Medicine

Background Allergic asthma is an inflammatory airway disease in which Th2 cytokines play an important role. Epithelial derived IL-25 has been suggested to be important in the maintenance of Th2-type responses. The effects of IL-25 are mediated by the IL-25 receptor, composed of two subunits IL-17RA and IL-17RB. Eosinophils are effector ceils in allergic *** role of IL-25 in eosinophil function is *** study examined the expression of IL-25 and it’s receptor on eosinophils in allergic asthmatics compared to atopic non-asthmatics and normal controls. Methods The expression of IL-25 and IL-17RA and

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1713-1727页

作者： Weiwei Tang Ziyi Chen Wenling Zhang Ye Cheng Betty Zhang Fan Wu Qian Wang Shouju Wang Dawei Rong F.P.Reiter E.N.De Toni Xuehao Wang Department of General Surgery Nanjing First HospitalNanjing Medical UniversityNanjingChina Hepatobiliary/Liver Transplantation Center The First Affiliated Hospital of Nanjing Medical UniversityKey Laboratory of Living Donor TransplantationChinese Academy of Medical SciencesNanjingChina Department of Gastroenterology The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Michael G.degroote school of medicine McMaster UniversityHamiltonONCanada Department of Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Department of medicine II University HospitalLMUMunichGermany Liver Center Munich University HospitalLMUMunichGermany

Sorafenib is a multikinase inhibitor capable of facilitating apoptosis,mitigating angiogenesis and suppressing tumor cell *** late-stage hepatocellular carcinoma(HCC),sorafenib is currently an effective first-line ***,the development of drug resistance to sorafenib is becoming increasingly *** study aims to identify factors contributing to resistance and ways to mitigate *** studies have shown that epigenetics,transport processes,regulated cell death,and the tumor microenvironment are involved in the development of sorafenib resistance in HCC and subsequent HCC *** study summarizes discoveries achieved recently in terms of the principles of sorafenib resistance and outlines approaches suitable for improving therapeutic outcomes for HCC patients.

关键词： sorafenib therapeutic hepatocellular

A Needs-Based Rheumatologist Education Program on Treating to Target in Psoriatic Arthritis and Spondyloarthropathy: Insights and Challenges

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Open Journal of Rheumatology and Autoimmune Diseases 2017年第1期7卷 53-64页

作者： Janet Pope Linda Wang Paul Tingey Angela Montgomery Art Karasik Pauline Boulos Vandana Ahluwalia Maggie Larche Sara Haig Nikhil Chopra Gina Rohekar Sherry Rohekar Schulich school of medicine & Dentistry University of Western Ontario London Canada St. Joseph’s Health Care London Canada Medical school Brisbane Australia Unit 502 Mississauga Canada Suite 202 Toronto Canada Rheumatology Division Department of Medicine Michael G. DeGroote School of Medicine McMaster University Hamilton Canada Suite 314 Brampton Canada Suite 411 London Canada

Objectives: To determine if comparative practice data and education for rheumatologists would change physician behavior for monitoring and treating psoriatic arthritis (PsA) and spondyloarthritis (SpA). Methods: Participating rheumatologists each performed a chart audit on 20 patients with PsA and SpA. Accredited education (determined by a survey and chart audits) and results of chart audits (comparing to other rheumatologists) were provided for each participant (intervention). Eight months later, a repeat chart audit by each participant was conducted on another 20 PsA and SpA patients. Changes in measurements collected, treatment given and patient characteristics pre and post intervention were analyzed. Results: Nine rheumatologists received the intervention. At baseline, most routinely monitored PsA and SpA for clinical and laboratory markers. In PsA, there was no change post-intervention in performing SJC (96%), TJC (≥91%), ESR (≥70%), CRP (≥73%), and CDAI (25%). In SpA, there were increased measurements of inflammatory markers (54% pre vs. 61% post for CRP), more NSAID use and decreased physical exam measures and HAQ but no significant changes. There were no major treatment differences pre and post intervention including NSAIDs, DMARDs and biologics. Conclusions: The rheumatologists frequently performed measurements of disease activity, did not change significantly with educational intervention so there may have been little room for improvement and many patients were already in a low disease state. Calculation of composite scores did not increase in PsA. The validity of physical exam and BASDAI as a measurement of disease activity were noted as concerns in applying a treat-to-target approach in SpA. Significance and Innovation: This study did not show a significant change in behavior for rheumatologists who had education based on care gaps and needs assessment in psoriatic arthritis and spondyloarthropathy. The rheumatologists identified that disease activity is

关键词： Education Seronegative Arthritis Psoriatic Arthritis Ankylosing Spondylitis Behavioral Change Outcome Assessments

Relative Contributions of Intraoperative Low Dose Ketamine, Lidocaine and Ketamine-Lidocaine Combination in Addition to Intrathecal Morphine for Postoperative Analgesia in Open Liver Resection: A Prospective, Randomized, Four-Arm, Triple Blind, Placebo-Controlled Trial

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Open Journal of Anesthesiology 2020年第9期10卷 313-326页

作者： Shalini Dhir Debashis Roy Tim Hall Yves Bureau Janice Yu Achal K. Dhir Department of Anesthesia and Perioperative medicine Schulich School of Medicine London Ontario Canada Sunnybrook Health Sciences Centre Department of Anesthesiology Toronto Ontario Canada Department of Anesthesia & Perioperative medicine Auckland Hospital University of Auckland Auckland New Zealand Department of Psychology Department of Medical Biophysics Western University London Ontario Canada Department of Anesthesia Michael G. DeGroote School of Medicine McMaster University Hamilton Ontario Canada

Background and Aims: Open liver resection requiring an upper abdominal incision is associated with significant opioid use due to postoperative pain. We tested the hypothesis that the intraoperative combination of low dose lidocaine and ketamine would reduce opioid consumption when given in conjunction with intrathecal morphine for liver resection surgery. Methods: In this triple blind, parallel group four-arm placebo-controlled trial, we randomized 124 adult ASA 2 - 4 liver resection patients to receive intraoperative lidocaine 0.33 mg/kg/h (group L), ketamine 70 μg/kg/h (group K), combination of lidocaine 0.33 mg/kg/h and ketamine 70 μg/kg/h (group KL) and saline (group P). All patients received 300 μg intrathecal morphine prior to induction of anesthesia. All infusions were started immediately after intubation and continued until the end of surgery. Primary outcome measurements included opioid consumption at 24-hours. Secondary outcomes included pain scores, opioid consumption at 48 and 72-hours and side effects including nausea, vomiting, dizziness, hallucinations, headaches and signs of local anaesthetic toxicity. Patients were followed up for 12 weeks. Results: There was no difference in the primary outcome of opioid consumption within all 4 groups at rest or movement at 24-hours. Secondary outcome of 48-hour rest pain score was significantly higher in the L group (p = 0.03) but without any difference in opioid use.

Preoperative Medication Management, Compliance and Adverse Events in Adult Patients Undergoing Elective Surgery: A Historical Chart Review

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Open Journal of Anesthesiology 2022年第3期12卷 113-133页

作者： James E. Paul Henry He Justin Diep Thuva Vanniyasingam Sean Middleton Department of Anesthesia McMaster University Hamilton ON Canada Michael G. degroote school of medicine McMaster University Hamilton ON Canada Department of Health Research Methods Evidence and Impact Biostatistics Unit St. Joseph’s Healthcare Hamilton Hamilton ON Canada

Purpose: Medication compliance for chronic medications has been well studied, but there is a gap in the literature regarding compliance within the perioperative period. Our objective was to determine the incidence of patient non-compliance with preoperative medication instructions for adult non-emergent surgery. Additional objectives were to identify predictors of compliance, describe medication instructions by drug type, and explore the impact of non-compliance. Patients and Methods: This historical chart review evaluated preoperative compliance to medication instructions in 393 adults undergoing non-emergent surgeries at Hamilton Health Sciences between May 1, 2012, and April 30, 2013. Seven patient factors (age;sex;American Society of Anesthesiologists class;number of medications;type of surgery;time between preoperative appointment to surgery;the individual collecting the medication list) were evaluated as potential predictors of non-compliance and analyzed using logistic regression analysis. Consequences of non-compliance were assessed by impact on intraoperative blood pressure, blood glucose level, drop in hemoglobin, bronchospasm, and case delays. Results: One hundred forty-six (37.2%) patients were non-compliant with one or more medication reconciliation instructions provided by the anesthesiologist. No significant associations were observed for any patient risk factors and non-compliance. Non-compliance was not associated with any clinically significant consequences. Conclusions: Our study shows that 37.15% of adult patients undergoing non-emergent surgery were non-compliant with medication instructions, although patients did not receive any written instructions for 46% of their medications. We did not identify any predictive patient factors or adverse outcomes associated with non-compliance.

关键词： Preoperative Medication Compliance Medication Adherence Perioperative Period Medication Reconciliation

Phishing行为及网络金融机构应对策略的博弈分析(英文)

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电子科技大学学报 2009年第S1期38卷 37-44页

作者：刘业政丁正平袁雨飞合肥工业大学管理学院合肥230009 The degroote school of Business Mcmaster University Canada

Phishing是近年来新出现的一种网络欺诈,是指欺诈者(Phisher)通过大量发送欺骗性垃圾邮件或采用其他的方式,意图引诱疏于防范的网络用户登陆假冒的知名站点,从而窃取个人敏感信息的一种攻击方式。这种欺诈行为给网络用户尤其是网络金融... 详细信息

Phishing是近年来新出现的一种网络欺诈,是指欺诈者(Phisher)通过大量发送欺骗性垃圾邮件或采用其他的方式,意图引诱疏于防范的网络用户登陆假冒的知名站点,从而窃取个人敏感信息的一种攻击方式。这种欺诈行为给网络用户尤其是网络金融机构的用户带来了大量的损失,也给网络金融机构带来了危害。该文在分析Phisher和网络金融机构的损益函数的基础上,建立了它们之间的二阶段动态博弈模型,并通过对纳什均衡的分析,求出了网络金融机构面对Phishing欺诈的最优策略。

关键词：基博弈网络金融机构 Phishing

Anatomical and Radiological Description of the Macaca fascicularis Spine in Comparison with the Human Spine

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Open Journal of Veterinary medicine 2022年第12期12卷 171-186页

作者： Anant Krishnan Guneet Kaleka Scott Emerson Guy Sovak Heather Simmons Kevin Brunner Dane Schalk John Sledge Amber Hoggatt Shanker Nesathurai Department of Diagnostic Radiology Oakland University William Beaumont School of Medicine Auburn Hills USA Department of Diagnostic Radiology and Molecular Imaging Beaumont Hospital Royal Oak USA Canadian Memorial Chiropractic College Toronto Canada Wisconsin National Primate Research Center Madison USA Lafayette Bone and Joint Clinic Lafayette USA Harvard Medical school Boston USA Department of Physical medicine and Rehabilitation Hamilton Health Sciences Corporation Hamilton Canada Division of Physical medicine and Rehabilitation Michael G. DeGroote School of Medicine McMaster University Hamilton Canada

Background: This paper describes and displays the spinal radiological anatomy and associated pathology in a Macaca fascicularis and compares it to the spinal anatomy of humans. Animal models are commonly used in research. As compared to Macaca mulatta, the anatomy of M. fascicularis is less well described in the literature. Materials and methods: The authors anatomically reconstructed and reviewed the defleshed spine of a single adult M. fascicularis visually, radiographically, and with high resolution CT. Results: 7 cervical, 12 thoracic, 6 lumbar, 3 sacral, and 16 caudal vertebrae were identified. Similarities in the spine to humans were seen as well as differences such as the beaked anterior arch of C1, the anterior pointed lower lumbar vertebrae, the upward curved transverse processes, and presence of three sacral segments. Degenerative changes were seen at multiple locations similar to humans though most pronounced at T3-4. Conclusions: This paper addresses the normal spinal anatomy and degenerative changes in an adult M. fascicularis and compares it to humans.

关键词： Macaca Fascicularis Macaques Spine Anatomy Radiology CT Comparative Study Computed Tomography