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Environmental Regulation of Antiviral Host Defense

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Environmental Regulation of Antiviral Host Defense

Collision Avoidance Strategy Supported by LTE-V-Based Vehicle Automation and Communication Systems for Car Following

中国生物工程学会第二届青年科技论坛暨首届青年工作委员会学术年会

作者： Pinglong Xu Life Sciences Institute and Innovation center for Cell Signaling network Zhejiang University

Cytosolic RNA/DNA sensing elicits primary defense against viral pathogens,by igniting cascades through MAVS or STING adaptor,TBK1 and IKKekinases and IRF3 transcriptional factor to summon antiviral ***,how the status ...

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Tsinghua Science and Technology 2020年第1期25卷 127-139页

作者： Jiayang Li Yi Zhang Mengkai Shi Qi Liu Yi Chen Department of Mathematics Tsinghua UniversityBeijing 100084China Beijing National Research center for Information Science and Technology(BNRist) Department of AutomationTsinghua UniversityBeijing 100084China Tsinghua-Berkeley Shenzhen Institute(TBSI) Shenzhen 518055China Jiangsu Province Collaborative Innovation center of Modern Urban Traffic Technologies Nanjing 210096China Beijing Nebula Link Tech.Co.Ltd Beijing 100080China network Technology Research Institute China UnicomBeijing 100044China

We analyzed and improved a collision avoidance strategy, which was supported by Long Term EvolutionVehicle(LTE-V)-based Vehicle-to-Vehicle(V2 V) communication, for automated vehicles. This work was completed in two steps. In the first step, we analyzed the probability distribution of message transmission time, which was conditional on transmission distance and vehicle density. Our analysis revealed that transmission time exhibited a near-linear increase with distance and density. We also quantified the trade-off between high/low resource reselection probabilities to improve the setting of media access parameters. In the second step, we studied the required safety distance in accordance with the response time, i.e., the transmission time, derived on the basis of a novel concept of Responsibility-Sensitive Safety(RSS). We improved the strategy by considering the uncertainty of response time and its dependence on vehicle distance and density. We performed theoretical analysis and numerical testing to illustrate the effectiveness of the improved robust RSS strategy. Our results enhance the practicability of building driverless highways with special lanes reserved for the exclusive use of LTE-V vehicles.

关键词： vehicle automation and communication collision avoidance Long Term Evolution-Vehicle(LTE-V) Responsibility-Sensitive Safety(RSS)

Novel insights into immune-related genes associated with type 2 diabetes mellitus-related cognitive impairment

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World Journal of Diabetes 2024年第4期15卷 735-757页

作者： Jing Gao Ying Zou Xiao-Yu Lv Li Chen Xin-Guo Hou Department of Endocrinology Qilu Hospital of Shandong UniversityCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina Institute of Endocrine and Metabolic Diseases Shandong UniversityJinan 250012Shandong ProvinceChina Key Laboratory of Endocrine and Metabolic Diseases Shandong Province Medicine&HealthJinan 250012Shandong ProvinceChina Department of Endocrinology Jinan Clinical Research Center for Endocrine and Metabolic DiseaseJinan 250012Shandong ProvinceChina

BACKGROUND The cognitive impairment in type 2 diabetes mellitus(T2DM)is a multifaceted and advancing state that requires further exploration to fully ***-roinflammation is considered to be one of the main mechanisms and the immune system has played a vital role in the progression of the *** To identify and validate the immune-related genes in the hippocampus associated with T2DM-related cognitive *** To identify differentially expressed genes(DEGs)between T2DM and controls,we used data from the Gene Expression Omnibus database *** identify T2DM module genes,we used Weighted Gene Co-Expression network *** the genes were subject to Gene Set Enrichment ***-protein interaction network construction and machine learning were utilized to identify three hub *** cell infiltration analysis was *** three hub genes were validated in GSE152539 via receiver operating characteristic curve *** experiments including reverse transcription quantitative real-time PCR,Western blotting and immunohistochemistry were conducted both in vivo and in *** identify potential drugs associated with hub genes,we used the Comparative Toxicogenomics Database(CTD).RESULTS A total of 576 DEGs were identified using *** taking the intersection of DEGs,T2DM module genes,and immune-related genes,a total of 59 genes associated with the immune system were ***,machine learning was utilized to identify three hub genes(H2-T24,Rac3,and Tfrc).The hub genes were associated with a variety of immune *** three hub genes were validated in *** experiments were conducted at the mRNA and protein levels both in vivo and in vitro,consistent with the bioinformatics ***,11 potential drugs associated with RAC3 and TFRC were identified based on the *** Immune-related genes that differ in expression in the hippocampus are closely linked to microgli

关键词： Bioinformatics analysis Type 2 diabetes mellitus Cognitive impairment Hippocampus Immune Microglia

Asymptotic Analysis of Transmission Capacities for Overlaid Spread-Spectrum Wireless networks

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China Communications 2010年第3期7卷 81-90页

作者： Huarui Wu Di Li Changchuan Yin Department of computer Application National Engineering Research Center for Information Technology in Agriculture Beijing 100097 China Key Laboratory of Universal Wireless Communications Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

We study the transmission capacities of two coexisting spread-spectrum wireless networks (a primary network vs. a secondary network) that operate in the same geographic region and share the same spectrum. We defi ne transmission capacity as the product among the density of transmissions, the transmission rate, and the successful transmission probability. The primary (PR) network has a higher priority to access the spectrum without particular considerations for the secondary (SR) network, while the SR network limits its interference to the PR network by carefully controlling the density ofits transmitters. Considering two types of spread-spectrum transmission schemes (FH-CDMA and DS-CDMA) and the channel inversion power control mechanism, we quantify the transmission capacities for these two networks based on asymptotic analysis. Our results show that if the PR network permits a small increase ofits outage probability, the sum transmission capacities of the two networks (i.e., the overall spectrumefficiency per unit area) will be boosted significantly over that of a single network.

关键词： transmission capacity ad hoc network spread spectrum stochastic geometry

A novel approach to model the role of mobility suppression and vaccinations in containing epidemics in a network of cities

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Infectious Disease Modelling 2024年第2期9卷 397-410页

作者： Leen Alrawas Abdessamad Tridane Ghassane Benrhmach Department of Physics New York University Abu DhabiAbu DhabiAbu DhabiUnited Arab Emirates Department of Mathematical Sciences United Arab Emirates UniversityAl AinAbu DhabiUnited Arab Emirates Emirates center for Mobility Research United Arab Emirates UniversityAl AinAbu DhabiUnited Arab Emirates Department of Statistics and Business Analytics United Arab Emirates UniversityAl AinAbu DhabiUnited Arab Emirates

This paper presents a comprehensive agent-based model for the spread of an infection in a network of *** mobility is defined between each two cities and can take different *** work examines the role that such mobility levels play in containing the infection with various vaccination coverage and age *** results indicate that mobility reduction is sufficient to control the disease under all circumstances and full lockdowns are not a *** has to be reduced to different ratios depending on the vaccination level and age distribution.A key finding is that increasing vaccination coverage above a certain level does not affect the mobility suppression level required to control the infection anymore for the cases of young population and heterogeneous age *** investigating several migration and commuting patterns,it is found that shutting mobility in a few local places is favored against reducing mobility over the entire country *** addition,commuting-and not migration-influences the spread level of the *** work offers an exclusive combined network-based and agent-based model that makes use of randomly generated mobility matrices.

关键词： Agent-based modeling network Epidemics

Interactive free-viewpoint video generation

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Virtual Reality & Intelligent Hardware 2020年第3期2卷 247-260页

作者： Yanru WANG Zhihao HUANG Hao ZHU Wei LI Xun CAO Ruigang YANG School of Electronic Science and Engineering Nanjing UniversityNanjing 210023China center on Frontiers of Computing Studies Peking UniversityBeijing 100871China Department of computer Science University of KentuckyLexingtonKY 40506USA

Background Free-viewpoint video(FVV)is processed video content in which viewers can freely select the viewing position and *** delivers an improved visual experience and can also help synthesize special effects and virtual reality *** this paper,a complete FVV system is proposed to interactively control the viewpoints of video relay programs through multimedia terminals such as computers and *** The hardware of the FVV generation system is a set of synchronously controlled cameras,and the software generates videos in novel viewpoints from the captured video using view *** interactive interface is designed to visualize the generated video in novel viewpoints and enable the viewpoint to be changed *** Experiments show that our system can synthesize plausible videos in intermediate viewpoints with a view range of up to 180°.

关键词： Free-viewpoint video View interpolation Interactive interface

3D Multilayered Turtle Shell Models for Image Steganography

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computer Modeling in Engineering & Sciences 2020年第11期124卷 879-906页

作者： Ji-Hwei Horng Juan Lin Yanjun Liu Chin-Chen Chang Quemoy University Kinmen County892TaiwanChina Engineering Research center for ICH Digitalization and Multi-Source Information Fusion Fuqing Branch of Fujian Normal UniversityFujian Province UniversityFuzhou350300China Department of Information Engineering and computer Science Feng Chia UniversityTaichung40724TaiwanChina School of computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China

By embedding secret data into cover images,image steganography can produce non-discriminable *** turtle shell model for data hiding is an excellent method that uses a reference matrix to make a good balance between image quality and embedding ***,increasing the embedding capacity by extending the area of basic structures of the turtle shell model usually leads to severe degradation of image *** this research,we innovatively extend the basic structure of the turtle shell model into a three-dimensional(3D)*** intrinsic properties of the original turtle shell model are well preserved in the 3D *** analysis shows that the new proposed models have good performance both in the image quality and in the complexity of the reference *** experimental results justify the theoretic conclusions.

关键词： 3D turtle shell data hiding reference matrix image quality

Automatic Eyewitness Identification During Disasters by Forming a Feature-Word Dictionary

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computers, Materials & Continua 2022年第9期72卷 4755-4769页

作者： Shahzad Nazir Muhammad Asif Shahbaz Ahmad Hanan Aljuaid Shahbaz Ahmad Yazeed Ghadi Zubair nawaz Department of computer Science National Textile UniversityFaisalabadPakistan computer Sciences Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman University(PNU)P.O.Box 84428Riyadh 11671Saudi Arabia Department of Software Engineering and computer Science Al Ain UniversityAbu DhabiUnited Arab Emirates Department of Data Science University of the PunjabPakistan

Social media provide digitally interactional technologies to facilitate information sharing and exchanging ***,in case of disasters,a massive corpus is placed on platforms such as *** accounts can benefit humanitarian organizations and agencies,but identifying the eyewitness Tweets related to the disaster from millions of Tweets is *** approaches have been developed to address this kind of *** recent state-of-the-art system was based on a manually created dictionary and this approach was further refined by introducing linguistic ***,these approaches suffer from limitations as they are dataset-dependent and not *** this paper,we proposed a method to identify eyewitnesses from *** experiment,we utilized 13 features discovered by the pioneer of this domain and can classify the tweets to determine the *** each feature,a dictionary of words was created with the Word Dictionary Maker algorithm,which is the crucial contribution of this *** algorithm inputs some terms relevant to a specific feature for its initialization and then creates the words ***,keyword matching for each feature in tweets is *** a feature exists in a tweet,it is termed as 1;otherwise,***,for 13 features,we created a file that reflects features in each *** classify the tweets based on features,Naïve Bayes,Random Forest,and Neural network were *** approach was implemented on different disasters like earthquakes,floods,hurricanes,and Forest *** results were compared with the state-of-the-art linguistic rule-based system with 0.81 F-measure *** the same time,the proposed approach gained a 0.88 value of *** results were comparable as the proposed approach is not ***,it can be used for the identification of eyewitness accounts.

关键词： Word dictionary social media eyewitness identification disasters

Influencing factors and mechanism of high-temperature oxidation of high-entropy alloys: A review

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International Journal of Minerals,Metallurgy and Materials 2021年第6期28卷 915-930页

作者： Ya Wei Yu Fu Zhi-min Pan Yi-chong Ma Hong-xu Cheng Qian-cheng Zhao Hong Luo Xiao-gang Li National Materials Corrosion and Protection Data center Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083China Key Laboratory for Corrosion and Protection of The Ministry of Education(MOE) Beijing 100083China BRI Southeast Asia network for Corrosion and Protection(MOE) Shunde Graduate School of University of Science and Technology BeijingFoshan 528000China

High-temperature oxidation is a common failure in high-temperature environments,which widely occur in aircraft engines and aerospace thrusters;as a result,the development of anti-high-temperature oxidation materials has been ***-based alloys are a common high-temperature material;however,they are too ***-entropy alloys are alternatives for the anti-oxidation property at high temperatures because of their special structure and *** recent achievements of high-temperature oxidation are reviewed in this *** high-temperature oxidation environment,temperature,phase structure,alloy elements,and preparation methods of high-entropy alloys are *** reason why high-entropy alloys have anti-oxidation ability at high temperatures is *** research,material selection,and application prospects of high-temperature oxidation are introduced.

关键词： high-entropy alloy high-temperature oxidation influencing factors oxidation mechanism