检索结果-南通市图书馆

Perilesional reorganization of motor function in stroke patients

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第21期5卷 1668-1672页

作者： Sung ho jang Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University

Perilesional reorganization is an important recovery mechanism for stroke patients because it yields good motor outcomes. however, perilesional reorganization remains poorly understood. The scientific basis for stroke rehabilitation can be established when detailed mechanisms of recovery are clarified. In addition, studies at the subcortical level remain in the early stages. Therefore, the present study suggested that additional investigations should focus on perilesional reorganization at the subcortical level, identifying the critical period for this mechanism and determining treatment strategies and modalities to facilitate development. The present study reviews literature focused on perilesional reorganization in stroke patients with regard to demonstration, clinical characteristics, and rehabilitative aspects, as well as previous studies of perilesional reorganization at cortical and subcortical levels.

关键词： stroke motor recovery functional MRI diffusion tensor imaging brain plasticity reorganization

Appearance of a neural bypass between injured cingulum and brainstem cholinergic nuclei of a patient with traumatic brain injury on follow-up diffusion tensor tractography images

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2015年第3期10卷 498-500页

作者： Han Do Lee Sung ho jang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam University

The human brain is known to contain a maximum of eight cholinergic nuclei： the basal forebrain region： the medial septal nucleus （Ch 1）, the vertical nucleus of the diagonal band （Ch 2）, the horizontal limb of the diago- nal band （Ch 3）, and the nucleus basalis of Meynert （Ch 4）; the brainstem： the pedunculopontine nucleus （Ch 5）, the laterodorsal tegmental nucleus （Ch 6）, and the para- bigeminal nucleus （Ch 8）; and the thalamus： the medial habenular nucleus （Ch 7）（Nieuwenhuys et al., 2008; Naidich and Duvernoy, 2009）. The cingulum is the neu- ral tract extending from the orbitofrontal cortex to the medial temporal lobe （Mufson and Pandya, 1984）. The cingulum plays an important role in memory because it is a passage of the medial cholinergic pathway, which pro- vides cholinergic innervations to the cerebral cortex after originating from Ch 1 and Ch 2 as well as Ch 4 （mainly）（Selden et al., 1998; Nieuwenhuys et al., 2008; hong and lang, 2010）.

关键词： Appearance of a neural bypass between injured cingulum and brainstem cholinergic nuclei of a patient with traumatic brain injury on follow-up diffusion tensor tractography images DTI

Corticospinal tract recovery in a patient with traumatic transtentorial herniation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2013年第5期8卷 469-473页

作者： Sang Seok Yeo Sung ho jang Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University

Transtentorial herniation is one of the causes of motor weakness in traumatic brain injury. In this study, we report on a patient who underwent decompressive craniectomy due to traumatic intracerebral hemorrhage. Brain CT images taken after surgery showed intracerebral hemorrhage in the left fronto-temporal lobe and left transtentorial herniation. The patient presented with severe paralysis of the right extremities at the time of intracerebral hemorrhage onset, but the limb motor function recovered partially at 6 months after onset and to nearly normal level at 27 months. Through diffusion tensor tractography, the left corticospinal tract was disrupted below the cerebral peduncle at 1 month after onset and the disrupted left corticospinal tract was reconstructed at 27 months. These findings suggest that recovery of limb motor function in a patient with traumatic transtentorial herniation can come to be true by recovery of corticospinal tract.

关键词： neural regeneration neuroimaging diffusion tensor imaging diffusion tensor tractography ttanscranial magnetic stimulation traumatic brain injury intracerebral hemorrhage transtentorfa herniation corticospinal tract motor paralysis neuroimaing grants-supported paper photographs-containing paper neuroregeneration

Pravastatin activates PPARα/PPARγexpression in the liver and gallbladder epithelium of hamsters

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2011年第2期10卷 185-190页

作者： Seok ho Dong Jin Lee Dong Hee Koh Min ho Choi Hyun Joo jang Sea Hyub Kae Division of Gastroenterology Department of Internal MedicineKyung Hee University College of Medicine Division of Gastroenterology Department of Internal MedicineHallym University College of Medicine

BACKGROUND:Our earlier study with cultured gallbladder epithelial cells demonstrated that statins(HMG-CoA reductase inhibitors)activate the expression of PPARαand PPARγ, consequently blocking the production of pro-inflmmatory *** present study used hamsters to investigate the effects of pavastatin on PPARα/PPARγexpression in the liver and gallbladder epithelium,and to determine whether pravastatin suppresses cholesterol crystal formation in the gallbladder. METhoDS:A total of 40 Golden Syrian male hamsters(4 weeks old)were randomly assigned to four groups(basal diet control; basal diet+pavastatin;high cholesterol diet;high cholesterol diet+pravastatin).All hamsters were 11 weeks old at the end of the *** liver,gallbladder and bile were harvested. Immunohistochemical staining and Western blotting for PPARαand PPARγwere performed in the liver and gallbladder. A drop of fresh bile was examined for cholesterol crystals under a microscope. RESULTS:In the gallbladder and liver of the hamsters, pravastatin activated the PPARαand PPARγexpression of gallbladder epithelial cells and hepatocytes,and particularly the response of PPARγwas much stronger than that of PPARα. Pravastatin suppressed the formation of cholesterol gallstones or crystals in the gallbladder. CONCLUSION:Pravastatin is an effective medication to activate PPARs(especially PPARγ)in the liver and the gallbladder epithelium of hamsters,and contributes to the prevention of gallstone formation.

关键词： pravastatin PPARα PPARγ hamster gallstone

Correlations between endoscopic and clinical disease activity indices in intestinal Behcet's disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第40期18卷 5771-5778页

作者： Hyun Jung Lee Youn Nam Kim Hui Won jang Han ho Jeon Eun Suk Jung Soo Jung Park Sung Pil hong Tae Il Kim Won ho Kim Chung Mo Nam Jae Hee Cheon Department of Internal Medicine Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea Department of Biostatistics Yonsei University College of MedicineSeoul 120-752South Korea Department of Preventive Medicine Yonsei University College of MedicineSeoul 120-752South Korea

AIM:To develop a novel endoscopic severity model of intestinal Behcet's disease(BD) and to evaluate its feasibility by comparing it with the actual disease activity index for intestinal Behcet's disease(DAIBD).METhoDS:We reviewed the medical records of 167 intestinal BD patients between March 1986 and April *** also investigated the endoscopic parameters including ulcer locations,distribution,number,depth,shape,size and margin to identify independent factors associated with *** endoscopic severity model was developed using significant colonoscopic variables identified by multivariate regression analysis and its correlation with the DAIBD was *** determine factors related to the discrepancy between endoscopic severity and clinical activity,clinical characteristics and laboratory markers of the patients were ***:A multivariate regression analysis revealed that the number of intestinal ulcers(≥ 2,P = 0.031) and volcanoshaped ulcers(P = 0.001) were predictive factors for the *** endoscopic severity model(Y) was developed based on selected endoscopic variables as follows:Y = 47.44 + 9.04 × non-Ileocecal area + 11.85 ×≥ 2 of intestinal ulcers + 5.03 × shallow ulcers + 12.76 × deep ulcers + 4.47 × geographicshaped ulcers + 26.93 × volcano-shaped ulcers + 8.65 ×≥ 20 mm of intestinal ***,endoscopic parameters used in the multivariate analysis explained only 18.9% of the DAIBD *** with severe DAIBD scores but with moderately predicted disease activity by the endoscopic severity model had more symptoms of irritable bowel syndrome(21.4% vs 4.9%,P = 0.026) and a lower rate of corticosteroid use(50.0% vs 75.6%,P = 0.016) than those with severe DAIBD scores and accurately predicted disease by the ***:Our study showed that the number of intestinal ulcers and volcano-shaped ulcers were predictive factors for severe DAIBD ***,the correlation between endoscopic severity and DAIBD(r = 0.434) was weak.

关键词：临床疾病肠道内镜多元回归分析评估模型严重程度开发利用有限元分析

Injury of the Papez circuit in a patient with traumatic spinal cord injury and concomitant mild traumatic brain injury

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2018年第1期13卷 161-162页

作者： Sung ho jang Hyeok Gyu Kwon Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Physical Therapy College of Health Sciences Catholic University of Pusan

Little is known about brain injury in concomitant mild traumatic brain injury （TBI） following traumatic spinal cord injury （TSCI）. In this study, we reported on a male patient with memory impairment who showed inj... 详细信息

关键词： DIFFUSION TENSOR TRACTOGRAPHY MEMORY TRACT

Predictive value of ^(18)F-fluorodeoxyglucose PET/CT for transarterial chemolipiodolization of hepatocellular carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第25期18卷 3215-3222页

作者： Myeong Jun Song Si Hyun Bae Ie Ryung Yoo Chung-Hwa Park Jeong Won jang ho Jong Chun Byung Gil Choi Hae Giu Lee Jong Young Choi Seung Kew Yoon Department of Internal Medicine College of MedicineThe Catholic University of KoreaSeoul 137-040South Korea Department of Nuclear Medicine College of MedicineThe Catholic University of KoreaSeoul 137-040South Korea Department of Radiology College of MedicineThe Catholic University of KoreaSeoul 137-040South Korea

Myeong Jun Song,Si Hyun Bae,Chung-Hwa Park,Jeong Won jang,Jong Young Choi,Seung Kew Yoon,Department of Internal Medicine,college of Medicine,The Catholic University of Korea,Seoul 137-040,South Korea Ie Ryung Yoo,Department of Nuclear,Medicine college of Medicine,The Catholic University of Korea,Seoul 137-040,South Korea ho Jong Chun,Byung Gil Choi,Hae Giu Lee,Department of Radiology,college of Medicine,The Catholic University of Korea,Seoul 137-040,South

关键词：肝癌预测显像计算机断层扫描应用价值评价标准改性反应

Effects of visual information regarding tactile stimulation on the somatosensory cortical activation：a functional MRI study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第7期12卷 1119-1123页

作者： Hyeok Gyu Kwon Sung ho jang Mi Young Lee Department of Physical Therapy College of Health Sciences Catholic University of Pusan Pusan Republic of Korea Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Daegu Republic of Korea Department of Physical Therapy College of Health and Therapy Daegu Haany University Gyeongsansi Republic of Korea

Many studies have investigated the evidence for tactile and visual interactive responses to activation of various brain ***,few studies have reported on the effects of visuo-tactile multisensory integration on the amount of brain activation on the somatosensory cortical *** aim of this study was to examine whether coincidental information obtained by tactile stimulation can affect the somatosensory cortical activation using functional *** right-handed healthy subjects were recruited for this *** tasks（tactile stimulation and visuotactile stimulation）were performed using a block paradigm during f MRI *** the tactile stimulation task,in subjects with eyes closed,tactile stimulation was applied on the dorsum of the right hand,corresponding to the proximal to distal directions,using a rubber *** the visuotactile stimulation task,tactile stimulation was applied to observe the attached mirror in the MRI chamber reflecting their hands being touched with the *** the result of SPM group analysis,we found brain activation on the somatosensory cortical *** stimulation task induced brain activations in the left primary sensory-motor cortex（SM1）and secondary somatosensory cortex（S2）.In the visuo-tactile stimulation task,brain activations were observed in the both SM1,both S2,and right posterior parietal *** all tasks,the peak activation was detected in the contralateral *** examined the effects of visuo-tactile multisensory integration on the SM1 and found that visual information during tactile stimulation could enhance activations on SM1 compared to the tactile unisensory stimulation.

关键词： nerve regeneration functional MRI somatosensory cortex somatosensory cortical activation visuotactile stimulation neural regeneration

Improvement of ataxia in a patient with cerebellar infarction by recovery of injured cortico-ponto-cerebellar tract and dentato-rubro-thalamic tract: a diffusion tensor tractography study

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第8期14卷 1470-1472页

作者： Sung ho jang Hyeok Gyu Kwon Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Daegu Republic of Korea Department of Physical Therapy College of Health Science Eulji University Gyeonggi Republic of Korea

Coordinated movement is generated by communication between the cerebrum and cerebellum via the cerebellar peduncles (CPs). The CPs are classified into three types (superior, middle, and inferior), and each includes a variety of neural tracts. Among those tracts, the cortico-ponto-cerebellar tract (CPCT), a middle CP, is involved in motor planning and initiation of movement, while the dentato-rubro-thalamic tract (DRTT), a superior CP, is involved in motor coordination, movement timing, verbal fluency, and working memory (Kase et al., 1993.

关键词： Improvement of ataxia injured cortico-ponto-cerebellar tractography study