检索结果-南通市图书馆

A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone loss

引用

骨研究:英文版 2023年第3期11卷 512-531页

作者： Fei Wei Zewen Kelvin Tuong Mahmoud Omer Christopher Ngo Jackson Asiatico Michael Kinzel Abinaya Sindu Pugazhendhi Annette R.Khaled Ranajay Ghosh Melanie Coathup Biionix Cluster and Department of Internal MedicineCollege of MedicineUniversity of Central FloridaOrlandoFLUSA Molecular Immunity Unit Department of MedicineUniversity of CambridgeCambridgeUK Cellular Genetics Wellcome Sanger InstituteHinxtonUK Department of Mechanical and Aerospace Engineering University of Central FloridaOrlandoFLUSA Burnett School of Biomedical Sciences College of MedicineUniversity of Central FloridaOrlandoFLUSA

Radiotherapy is a critical component of cancer care but can cause osteoporosis and pathological insufficiency fractures in surrounding and otherwise healthy ***,no effective countermeasure exists,and ionizing radiation-induced bone damage continues to be a substantial source of pain and *** purpose of this study was to investigate a small molecule aminopropyl carbazole named P7C3 as a novel radioprotective *** studies revealed that P7C3 repressed ionizing radiation(IR)-induced osteoclastic activity,inhibited adipogenesis,and promoted osteoblastogenesis and mineral deposition in *** also demonstrated that rodents exposed to clinically equivalent hypofractionated levels of IR in vivo develop weakened,osteoporotic ***,the administration of P7C3 significantly inhibited osteoclastic activity,lipid formation and bone marrow adiposity and mitigated tissue loss such that bone maintained its area,architecture,and mechanical *** findings revealed significant enhancement of cellular macromolecule metabolic processes,myeloid cell differentiation,and the proteins LRP-4,TAGLN,ILK,and Tollip,with downregulation of GDF-3,SH2B1,and *** proteins are key in favoring osteoblast over adipogenic progenitor differentiation,cell matrix interactions,and shape and motility,facilitating inflammatory resolution,and suppressing osteoclastogenesis,potentially via Wnt/β-catenin signaling.A concern was whether P7C3 afforded similar protection to cancer ***,and remarkably,at the same protective P7C3 dose,a significant reduction in triple-negative breast cancer and osteosarcoma cell metabolic activity was found in ***,these results indicate that P7C3 is a previously undiscovered key regulator of adipo-osteogenic progenitor lineage commitment and may serve as a novel multifunctional therapeutic strategy,leaving IR an effective clinical tool while diminishing the risk of adverse post-IR *** data uncov

关键词： protective inhibited prevention

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fe_(3)O_(4)对黄铜矿在酸性硫酸铁溶液中铜溶解氧化还原反应的影响

引用

Transactions of Nonferrous Metals Society of China 2024年第6期34卷 1965-1975页

作者： Kolela J NYEMBWE Elvis FOSSO-KANKEU Frans WAANDERS Martin MKANDAWIRE Didier K NYEMBWE Bhekie B MAMBA Water Pollution Monitoring and Remediation Initiatives Research Group School of Chemical and Minerals EngineeringFaculty of EngineeringNorth-West UniversityPotchefstroomSouth Africa Department of Mining Engineering College of Science Engineering and TechnologyUniversity of South AfricaFlorida Science CampusJohannesburgSouth Africa Department of Metallurgy Faculty of Engineering and Built EnvironmentUniversity of JohannesburgDoornfonteinJohannesburgSouth Africa Department of Chemistry School of Science and TechnologyCape Breton UniversityCanada School of Mining Metallurgy and Chemical EngineeringFaculty of Engineering and the Built EnvironmentUniversity of JohannesburgJohannesburgSouth Africa Institute for Nanotechnology and Water Sustainability College of Science Engineering and TechnologyUniversity of South AfricaFlorida Science CampusJohannesburgSouth Africa

由于钝化层的形成,黄铜矿(CuFeS_(2))在氧化条件下浸出通常具有溶解速率缓慢的特点。为了将黄铜矿浸出过程中的钝化效应降至最低并提高铜的回收率,研究了CuFeS_(2)在不同pH值(1.0、1.5和1.8)和温度(25和50℃)条件下浸出时,向Fe_(2)(SO_(... 详细信息

由于钝化层的形成,黄铜矿(CuFeS_(2))在氧化条件下浸出通常具有溶解速率缓慢的特点。为了将黄铜矿浸出过程中的钝化效应降至最低并提高铜的回收率,研究了CuFeS_(2)在不同pH值(1.0、1.5和1.8)和温度(25和50℃)条件下浸出时,向Fe_(2)(SO_(4))_(3)−H_(2)SO_(4)浸出剂中添加磁铁矿(Fe_(3)O_(4))对铜溶解速率的影响。结果表明,溶液pH值、电位和温度在溶解过程中起着关键作用。在pH 1.8、50℃和400 mV的条件下,Fe_(3)O_(4)−CuFeS_(2)混合体系中铜的回收率达到最大值(70%),而未添加Fe_(3)O_(4)时,CuFeS_(2)中铜的回收率较低(48%)。添加Fe_(3)O_(4)有助于维持较高的氧化还原值。添加Fe_(3)O_(4)还使活化能从79.04 kJ/mol降低到53.69 kJ/mol。这表明,当Fe_(3)O_(4)存在时,由于形成了更易溶解的中间体斑铜矿(Cu_(5)FeS_(4))和辉铜矿(Cu_(2)S),CuFeS_(2)更易被氧化。两种溶解过程都受到矿物表面的化学控制。此外,对浸出残渣的矿物学分析表明,当无Fe_(3)O_(4)存在时,作为表面钝化物的黄钾铁矾浓度较高。因此,添加Fe_(3)O_(4)减少了钝化层的形成,提升了铜的回收率。

关键词：黄铜矿溶解磁铁矿电偶钝化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Monitor and Acceptance among Couples in Romantic Relationships:Actor-Partner Interdependence Models Based on the Monitor and Acceptance Theory

引用

International Journal of Mental Health Promotion 2024年第7期26卷 589-598页

作者： Xue Wen Yuyang Zhou Jiaxuan Du Xiaoyan Liu Wei Xu Beijing Key Laboratory of Applied Experimental Psychology National Demonstration Center for Experimental Psychology Education(Beijing Normal University)Faculty of PsychologyBeijing Normal UniversityBeijing100875China School of Psychology Nanjing Normal UniversityNanjing210097China college of Business Florida International UniversityMiamiFL 11200USA School of Philosophy Psychology and Language SciencesUniversity of EdinburghEdinburghEH89YLUK

Communication could be an essential part of couples in their daily *** on Monitor and Acceptance Theory(MAT),the present study explored the mediating role of communication in the relationship between mindfulness and relationship quality among college-student *** research examined the dynamic relationship of monitoring and acceptance to relationship satisfaction in the Actor-Partner Interdependence Model(APIM),and the mediating effect of positive or negative communications in these relationships.A total of 96 pairs of couples in the universities in Nanjing,China participated in the *** measurements were used to measure the momentary levels of their monitor,acceptance,positive/negative communication,and relationship satisfaction.A Hierarchical Linear Model(HLM)was used to deal with the *** showed that the women’s monitor facet of state mindfulness negatively predicted men’s relationship satisfaction through women’s negative communication,and the women’s acceptance facet of state mindfulness positively predicted women’s relationship satisfaction through women’s positive and negative communication at the within-person *** study highlights the importance of cooperation in monitoring and acceptance for couples to own and hold high levels of relationship satisfaction.

关键词： Romantic relationship communication mindfulness monitor acceptance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Promising applications of D-amino acids in periprosthetic joint infection

引用

Bone Research 2023年第2期11卷 248-272页

作者： Matthew Caldwell Megan Hughes Fei Wei Christopher Ngo Raven Pascua Abinaya Sindu Pugazhendhi Melanie J.Coathup Biionix Cluster&college of Medicine University of Central FloridaBlvdOrlandoFL32827USA School of Biosciences Cardiff UniversityCF103AT WalesUK Burnett School of Biomedical Sciences College of MedicineUniversity of Central Florida6900 Lake NonaBlvdOrlandoFL32827USA

Due to the rise in our aging population,a disproportionate demand for total joint arthroplasty(TJA)in the elderly is *** joint infection(PJI)represents one of the most challenging complications that can occur following TJA,and as the number of primary and revision TJAs continues to rise,an increasing PJI burden is *** advances in operating room sterility,antiseptic protocols,and surgical techniques,approaches to prevent and treat PJI remain difficult,primarily due to the formation of microbial *** difficulty motivates researchers to continue searching for an effective antimicrobial *** dextrorotatory-isoforms of amino acids(D-AAs)are essential components of peptidoglycan within the bacterial cell wall,providing strength and structural integrity in a diverse range of *** many tasks,D-AAs regulate cell morphology,spore germination,and bacterial survival,evasion,subversion,and adhesion in the host immune *** administered exogenously,accumulating data have demonstrated that D-AAs play a pivotal role against bacterial adhesion to abiotic surfaces and subsequent biofilm formation;furthermore,D-AAs have substantial efficacy in promoting biofilm *** presents D-AAs as promising and novel targets for future therapeutic *** their emerging antibacterial efficacy,their role in disrupting PJI biofilm formation,the disassembly of established TJA biofilm,and the host bone tissue response remains largely *** review aims to examine the role of D-AAs in the context of *** to date suggest that D-AA bioengineering may serve as a promising future strategy in the prevention and treatment of PJI.

关键词： prevention spite furthermore

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Intelligent MCGDM Model in Green Suppliers Selection Using Interactional Aggregation Operators for Interval-Valued Pythagorean Fuzzy Soft Sets

引用

Computer Modeling in Engineering & Sciences 2024年第5期139卷 1829-1862页

作者： Rana Muhammad Zulqarnain Wen-Xiu Ma Imran Siddique Hijaz Ahmad Sameh Askar School of Mathematical Sciences Zhejiang Normal UniversityJinhua321004China Department of Mathematics and Statistics University of South FloridaTampaFL 33620-5700USA School of Mathematical and Statistical Sciences North-West UniversityMafikeng CampusMmabatho2735South Africa Department of Mathematics University of SargodhaSargodha40100Pakistan Section of Mathematics International Telematic University UninettunoCorso Vittorio Emanuele IIRoma00186Italy Near East University Operational Research Center in HealthcareNicosia/Mersin99138Turkey Department of Statistics and Operations Research College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

Green supplier selection is an important debate in green supply chain management(GSCM),attracting global attention from scholars,especially companies and *** frequently search for new ideas and strategies to assist them in realizing sustainable *** of the speculative character of human opinions,supplier selection frequently includes unreliable data,and the interval-valued Pythagorean fuzzy soft set(IVPFSS)provides an exceptional capacity to cope with excessive fuzziness,inconsistency,and inexactness through the decision-making *** main goal of this study is to come up with new operational laws for interval-valued Pythagorean fuzzy soft numbers(IVPFSNs)and create two interaction operators-the intervalvalued Pythagorean fuzzy soft interaction weighted average(IVPFSIWA)and the interval-valued Pythagorean fuzzy soft interaction weighted geometric(IVPFSIWG)operators,and analyze their *** operators are highly advantageous in addressing uncertain problems by considering membership and non-membership values within intervals,providing a superior solution to other ***,specialist judgments were calculated by the MCGDM technique,supporting the use of interaction AOs to regulate the interdependence and fundamental partiality of green supplier assessment ***,a statistical clarification of the planned method for green supplier selection is presented.

关键词： Interval-valued Pythagorean fuzzy soft set IVPFSIWA operator IVPFSIWG operator MCGDM SCM

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Unsupervised full-color cellular image reconstruction through disordered optical fiber

引用

Light(Science & Applications) 2023年第6期12卷 1091-1102页

作者： Xiaowen Hu Jian Zhao Jose Enrique Antonio-Lopez Rodrigo Amezcua Correa Axel Schülzgen CREOL The College of Optics and PhotonicsUniversity of Central FloridaOrlandoFL 32816USA The Picower Institute for Learning and Memory Massachusetts Institute of TechnologyCambridgeMA 02139USA

Recent years have witnessed the tremendous development of fusing fiber-optic imaging with supervised deep learning to enable high-quality imaging of hard-to-reach ***,the supervised deep learning method imposes strict constraints on fiber-optic imaging systems,where the input objects and the fiber outputs have to be collected in *** unleash the full potential of fiber-optic imaging,unsupervised image reconstruction is in ***,neither optical fiber bundles nor multimode fibers can achieve a point-to-point transmission of the object with a high sampling density,as is a prerequisite for unsupervised image *** recently proposed disordered fibers offer a new solution based on the transverse Anderson ***,we demonstrate unsupervised full-color imaging with a cellular resolution through a meter-long disordered fiber in both transmission and reflection *** unsupervised image reconstruction consists of two *** the first stage,we perform a pixel-wise standardization on the fiber outputs using the statistics of the *** the second stage,we recover the fine details of the reconstructions through a generative adversarial *** image reconstruction does not need paired images,enabling a much more flexible calibration under various *** new solution achieves full-color high-fidelity cell imaging within a working distance of at least 4 mm by only collecting the fiber outputs after an initial *** imaging robustness is also demonstrated when the disordered fiber is bent with a central angle of 60°.Moreover,the cross-domain generality on unseen objects is shown to be enhanced with a diversified object set.

关键词： fiber optical image

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Post-op cocaine use resulting in catastrophic cardiovascular compromise

引用

Journal of Geriatric Cardiology 2023年第2期20卷 155-158页

作者： Abhinav Karan Aleem Azal Ali Khadeeja Esmail Temitope Akinjogbin Sanjay Lamsal Emil Missov Internal Medicine University of Florida College of Medicine-JacksonvilleFloridaUSA Division of Cardiology University of Florida College of Medicine-JacksonvilleFloridaUSA Department of Radiology University of Florida College of Medicine-JacksonvilleFloridaUSA

Cardiac tamponade can result from a variety of intrapericardial or extrapericardial sources of compression of the heart and great *** tamponade can be acute or subacute and results from fluid or gas collection in the pericardial space leading to impairment in cardiac *** cardiac tamponade following open heart surgery can be caused by hemorrhage within the pericardial sac or by mediastinal hematoma formation.

关键词： cardiac function acute

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tricuspid valve avulsion

引用

Journal of Geriatric Cardiology 2023年第4期20卷 317-318页

作者： Abhinav Karan Anamarys Blanco Emil Missov Srinivasan Sattiraju Internal Medicine University of Florida College of Medicine-JacksonvilleFloridaUSA Department of Cardiology University of Florida College of Medicine-JacksonvilleFloridaUSA

A 71-year-old male with a medical history of sick sinus syndrome with dual-chamber pacemaker system implantation six years prior,and hypertension presented to the emergency department with complaints of generalized ma... 详细信息

关键词： hypertension implantation fever

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

All-optical sampling of few-cycle infrared pulsesusing tunneling in a solid

引用

Photonics Research 2021年第6期9卷 929-936页

作者： YANGYANG LIU SHIMA GHOLAM-MIRZAEI JOHN E.BEETAR JONATHAN NESPER AHMED YOUSIF M.NRISIMHAMURTY MICHAEL CHINI Department of Physics University of Central FloridaOrlandoFlorida 32816USA CREOL The College of Optics and PhotonicsUniversity of Central FloridaOrlandoFlorida 32816USA

Recent developments in ultrafast laser technology have resulted in novel few-cycle sources in the *** characterizing the time-dependent intensities and electric field waveforms of such laser pulses is essential to their applications in strong-field physics and attosecond pulse generation,but this remains a ***,it was shown that tunnel ionization can provide an ultrafast temporal“gate”for characterizing highenergy few-cycle laser waveforms capable of ionizing ***,we show that tunneling and multiphoton excitation in a dielectric solid can provide a means to measure lower-energy and longer-wavelength pulses,and we apply the technique to characterize microjoule-level near-and mid-infrared *** method lends itself to both all-optical and on-chip detection of laser waveforms,as well as single-shot detection geometries.

关键词： optical tunneling cycle

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Invasive versus non-invasive hemodynamic monitoring of heart failure patients and their outcomes

引用

Journal of Geriatric Cardiology 2022年第4期19卷 315-318页

作者： Fadi Kandah Pooja Dhruva Raj Shukla Maedeh Ganji Carlos Palacio Emil Missov Jose Ruiz-Morales Internal Medicine University of Florida College of Medicine-JacksonvilleJacksonvilleFloridaUSA Division of Cardiology University of Florida College of Medicine-JacksonvilleJacksonvilleFloridaUSA

Acute decompensated heart failure(HF)is the most common cause of hospital ad-mission in patients older than 65 *** length of hospital stay is about 5-6 days and with a frequent number of hospital readmission rates of 25%to 50%at 30 days and 6-12 months,respect-ively.[1]Treatment options are vast and depend on certain patient characteristics,including hemody-namics,which drive the acute management.A pop-ular modality to assess hemodynamics in acute HF is the right heart catheterization(RHC).While in-vasive,the use of RHC gives providers the oppor-tunity to evaluate values that directly contribute to the management of the *** numbers can calculate the cardiac output as well as help establish the underlying etiology of the patient’s symptoms and guide therapy.

关键词： patients acute Acute

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：