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Design and development of an ACCT for the Shanghai advanced proton therapy facility

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Nuclear Science and Techniques 2022年第10期33卷 41-52页

作者： Hong Zhang Jun-Zhou Li Rui Hou Sun An Shi-Quan Xu You-Chun Liu Peng-Jiao Zhang Jie Song Yue-Lin Zhang college of Engineering and applied sciences Nanjing UniversityNanjing 210093China

The Shanghai advanced proton therapy facility is a proton cancer treatment device designed and built by the Shanghai Institute of applied physics at the Chinese academy of *** accelerator part comprises a proton linear accelerator(linac)injector and a circular *** alternating current current transformer(ACCT)is used for non-intercepting beam current measurement at the drift tube linac *** to the beam characteristics,the ACCT is required to complete real-time beam current and pulse width measurements at currents of3-30 mA,frequencies of 1-10 Hz,and pulse widths of40-400μ*** this paper,we report the design and development of an *** designed ACCT was simulated using CST Microwave Studio,and calibrated using an oscilloscope and signal *** in the output signal of the ACCT were investigated as a function of ceramic gap size,number of coil turns,and *** to the simulation and experimental results,the optimal number of coil turns was found to be *** addition,a low-pass filter was adopted to filter the noise introduced during long-distance signal transmission using a coaxial cable with the length of 20 *** calibration results show that the corresponding rise time of the ACCT is 800 ns with the sensitivity of 8.2 V/A and a droop of less than 1%,meeting the design requirements.

关键词： Beam current monitors ACCT Particle beam diagnostics

Boosting Oxygen Evolution Reaction Performance on NiFe‑Based Catalysts Through d‑Orbital Hybridization

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Nano-Micro Letters 2025年第1期17卷 281-292页

作者： Xing Wang Wei Pi Sheng Hu Haifeng Bao Na Yao Wei Luo State Key Laboratory of New Textile Materials and Advanced Processing Technology Key Laboratory of New Textile Materials and Applications of Hubei ProvinceSchool of Materials Science and EngineeringWuhan Textile UniversityWuhan 430200People’s Republic of China college of Chemistry and Molecular sciences Wuhan UniversityWuhan 430072People’s Republic of China

Anion-exchange membrane water electrolyzers(AEMWEs)for green hydrogen production have received intensive attention due to their feasibility of using earth-abundant NiFe-based *** introducing a third metal into NiFe-based catalysts to construct asymmetrical M-NiFe units,the d-orbital and electronic structures can be adjusted,which is an important strategy to achieve sufficient oxygen evolution reaction(OER)performance in ***,the ternary NiFeM(M:La,Mo)catalysts featured with distinct M-NiFe units and varying d-orbitals are reported in this *** and theoretical calculation results reveal that the doping of La leads to optimized hybridization between d orbital in NiFeM and 2p in oxygen,resulting in enhanced adsorption strength of oxygen intermediates,and reduced rate-determining step energy barrier,which is responsible for the enhanced OER *** critically,the obtained NiFeLa catalyst only requires 1.58 V to reach 1 A cm^(−2) in an anion exchange membrane electrolyzer and demonstrates excellent long-term stability of up to 600 h.

关键词： NiFe-based catalysts d-orbital coupling Oxygen evolution reaction Anion exchange membrane electrolyzer

Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)

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Chinese Journal of Polymer Science 2018年第5期36卷 604-611页

作者： Yan Zhang Zi-Peng Yuan Yu Qin Ji Dai Tao Zhang Department of Biomedical Engineering College of Engineering and Applied Sciences Nanjing University

Poly（vinyl chloride）（PVC） is one of the mostly produced plastics in the world and is widely used in single-use medical devices. However, the additives that are often necessary for PVC arouse concerns of its safety, thus quests the modifications of PVC itself. In this study, poly（ethylene glycol）（PEG） and polydimethylsiloxane（PDMS） segments were grafted onto PVC backbone in similar ways, and the chemical structures of the modified PVCs were characterized by Fourier transform infrared spectra, X-ray photoelectron spectra, thermogravimetric analysis and differential scanning calorimetry. Moreover, the water contact angle, protein adsorption, platelet adhesion, cell attachment and proliferation on different material surfaces were studied and compared. It was found that both PEG and PDMS grafting yielded improvement on biocompatibility compared with bare PVC, while hydrophobic PDMS grafted PVC showed more effective on cell attachment and proliferation than that of hydrophilic PEG grafted PVC.

关键词： Poly(vinyl chloride) Poly(ethylene glycol) Polydimethylsiloxane Grafting Biomedical properties

Composting of Disposal Organic Wastes: Resource Recovery for Agricultural Sustainability

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过程工程学报 2006年第4期6卷 585-591页

作者： Mohammad H.Golabi Peggy Denney Clancy Iyekar college of Natural and applied sciences University of Guam Mangilao Guam-USA

One of the major problems of agricultural soils in the tropical regions of the Pacific is the low organic matter *** of the hot and humid environment,the soil organic matter(SOM)is minimal due to rapid *** organic material is being applied on agricultural fields as an amendment to provide nutrients and enhance the organic matter content for improving the physical and chemical properties of the cultivated *** addition land application of composted material as a fertilizer source effectively disposes of wastes that otherwise are buried in *** our soil program at the University of Guam,we are evaluating the use of organic material as an alternative to synthetic *** goal is to develop management strategies and use available resources for improving crop production while conserving resources and preserving environmental *** case study project is designed to improve soil fertility status by using composted organic wastes and assessing how the nitrogen and other essential nutrients contribute to long-term soil fertility and crop productivity without application of synthetic *** our pilot project,compost is produced from wood chips,grinded typhoon debris mixed with animal manure,fish feed,shredded paper and other organic *** compost is then applied on the field at the rates of 0,5,10 and 20 t/ha as a soil amendment on the eroded cobbly soils of southern *** is planted and monitored for growth performance and *** effect of land application of composted material on the SOM content and overall soil quality indices are being evaluated in this pilot study.

关键词： composting resource recovery management soil improvement waste disposal agricultural sustainability

一种基于偶氮键一级断裂与C–C键二级断裂释放药物的β-lapachone高分子纳米前药用于肿瘤选择性治疗（英文）

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Science China Materials 2025年

作者：赵唯栋郑梦飞褚虹宇张景宣王昆杨晨光沈娜汤朝晖 Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences School of applied Chemistry and Engineering University of Science and Technology of China Department of Gastrointestinal Colorectal and Anal Surgery China-Japan Union Hospital of Jilin University Department of Pathogenbiology State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases College of Basic Medicine Jilin University

lapachone (β-Lap)是一种极具潜力的邻萘醌类抗肿瘤药物,但β-Lap临床应用受限于低水溶性和严重的毒副作用.前药修饰策略可有效增强药物的肿瘤选择性,但β-Lap受限于缺乏可修饰基团.本文设计了一种新型偶氮键一级断裂和碳碳键(C–C)二...

lapachone (β-Lap)是一种极具潜力的邻萘醌类抗肿瘤药物,但β-Lap临床应用受限于低水溶性和严重的毒副作用.前药修饰策略可有效增强药物的肿瘤选择性,但β-Lap受限于缺乏可修饰基团.本文设计了一种新型偶氮键一级断裂和碳碳键(C–C)二级断裂的β-Lap高分子纳米前药(Azo-Lap NP),自消除的对氨基苯基连接子通过偶氮键连接聚谷氨酸,在高表达NQO1和低pH的肿瘤环境下,实现肿瘤响应性β-Lap释放. Azo-Lap NPs对β-Lap的有效共价负载可显著提高β-Lap的给药剂量,并延长药物的肿瘤停留时间.此外, Azo-Lap NPs通过避免溶血和高铁血红蛋白的产生显著降低β-Lap的毒副作用.通过小鼠抑瘤实验验证了Azo-Lap NPs安全性.在4T1模型中, Azo-Lap NPs组的抑瘤率明显高于β-Lap组.本研究为肿瘤选择性递送β-Lap提供了一种更有效且安全的高分子纳米前药.

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Efficient and simple synthesis of B_(2)O_(3)-Al_(2)O_(3)nanocomposites assisted by deep eutectic solvent for production of 5-hydroxymethylfurfural from glucose

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Nano Research 2025年第1期18卷 236-248页

作者： Yuchen Wang Kai Rong Shanlei Chang Youxing Fang Shaojun Dong State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China college of Chemistry Jilin UniversityChangchun 130012China

The catalytic conversion of glucose to high valueadded platform chemical 5-hydroxymethylfurfural(HMF)is a promising biorefinery process,and alumina-boria catalysts are considered to be green and mild solid acid catalysts for this catalytic ***,compared to the common synthesis methods with complicated steps,we reported a simple and efficient strategy to prepare B_(2)O_(3)-Al_(2)O_(3)nanocomposites by calcining cost-effective glucose-urea deep eutectic solvent(DES)solution containing the *** prepared B_(2)O_(3)-Al_(2)O_(3)nanocomposites exhibited an open three-dimensional skeleton and two-dimensional porous lamellar substructure,endowing them with a high specific surface area(228.27 m2/g).The introduction of boron changed the ratios of different aluminum species(AlⅣ,AlⅤ,and AlⅥ)and borate species(BO3 and BO4),thus further affecting the acidity and the types of acid sites of the *** prepared B_(2)O_(3)-Al_(2)O_(3)bifunctional acid catalysts possessing abundant Lewis acid sites and adjustable Brønsted acid sites showed complete glucose conversion and 55.38%of HMF yield under the optimum *** study proposed a concise method to synthesize alumina-boria solid acid catalysts assisted by glucose-urea *** hope to extend the application and prospect of this efficient and simple synthesis strategy.

关键词： 5-hydroxymethylfurfural(HMF) deep eutectic solvent glucose alumina-boria acid catalyst

An AND-type 1T-FeFET array with robust write and read operations

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Science China(Information sciences) 2025年

作者： Jiacheng XU Jiayi ZHAO Hongrui ZHANG Haoji QIAN Jiani GU Bowen CHEN Gaobo LIN Rongzong SHEN Xinda SONG Huan LIU Yian DING Minglei MA Miaomiao ZHANG Xiao YU Bing CHEN Ran CHENG Gaobo XU Huaxiang YIN Yan LIU Jiajia CHEN Chengji JIN Genquan HAN Hangzhou Institute of Technology and School of Microelectronics Xidian University Zhejiang Lab college of Integrated Circuits Zhejiang University Key Laboratory of Microelectronics Devices and Integrated Technology Institute of MicroelectronicsChinese Academy of Sciences

HfO2-based ferroelectric field-effect transistor （FeF ET） has become a promising solution for next-generation embedded non-volatile memory （NVM） owing to its complementary metal-oxide-semiconductor （CMOS） compatibility,small footprint, high performance, and non-destructive readout [1]. Recent research of HfO2-based FeF ET has focused on the device operation mechanisms as well as reliability issues such as the interplay between polarization switching and charge trapping/detrapping [2], read-after-write latency [3] and endurance degradation [4]. It has been demonstrated that endurance higher than 1010cycles with negligible read-after-write latency is possible if the gate stack of FeF ET is well engineered [5].

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A spotlight on dosage and subject selection for effective neuroprotection: exploring the central role of mitochondria

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Neural Regeneration Research 2025年第4期20卷 1081-1082页

作者： John Mitrofanis Jonathan Stone Michael R.Hamblin Pierre Magistretti Alim-Louis Benabid Glen Jeffery Fonds Clinatec UniversitéGrenoble AlpesGrenobleFrance School of Medical Science University of SydneySydneyAustralia Faculty of Health sciences University of JohannesburgJohannesburgSouth Africa King Abdullah University of Science and Technology ThuwalSaudi Arabia Institute of Ophthalmology University College LondonLondonUK

Neurons are notoriously vulnerable cell *** the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological conditions,including stroke,head trauma,and neurodegenerative disease,can generate stress in neurons,affecting their survival and proper *** most neural pathologies,mitochondria become dysfunctional and this plays a pivotal role in the process of cell *** challenge over the last few decades has been to develop effective interventions that improve neuronal homeostasis under pathological *** interventions,often referred to as disease-modifying or neuroprotective,have,however,proved frustratingly elusive,at both preclinical and,in particular,clinical *** this perspective,we highlight two factors that we feel are key to the development of effective neuroprotective *** are:firstly,the choice of dose of intervention and method of application,and secondly,the selection of subjects,whether they be patients or the animal model.

关键词： protective dosage distress

半透明有机太阳能电池器件工程的最新进展（英文）

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Science China Materials 2025年

作者：朱陈宇杰郑昊霖赵垄堂朱晓张 Beijing National Laboratory for Molecular sciences CAS Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences School of Chemical sciences University of Chinese Academy of Sciences School of Chemistry College of Science and Engineering University of Edinburgh

半透明有机光伏(ST-OPV)是一种新型的绿色能源获取技术,是有机光伏应用中最有前景的领域之一.由于其活性层材料本征的吸收光谱可调特性,质轻可柔, ST-OPV与无机光伏相比,在可穿戴设备、自供电温室屋顶和建筑集成光伏一体化等方面具有独...

半透明有机光伏(ST-OPV)是一种新型的绿色能源获取技术,是有机光伏应用中最有前景的领域之一.由于其活性层材料本征的吸收光谱可调特性,质轻可柔, ST-OPV与无机光伏相比,在可穿戴设备、自供电温室屋顶和建筑集成光伏一体化等方面具有独特的潜力.为了进一步提高ST-OPV的实用性,提升光利用效率(LUE)仍然是研究的重点.因此,本文从半透明器件理论模型、透明顶电极材料、光学修饰策略和活性层材料选择等方面回顾了ST-OPV的研究进展,希望为STOPV的研究提供一定的借鉴.

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