检索结果-南通市图书馆

Recent Strategies and advances in Hydrogel-Based Delivery Platforms for Bone Regeneration

NANO-MICRO LETTERS 2025年第1期17卷 1-51页

作者： Wang, Xiao Zeng, Jia Gan, Donglin Ling, Kun He, Mingfang Li, Jianshu Lu, Yongping Guangyuan Cent Hosp Sci & Technol Innovat Ctr Biomed Mat & Clin Res Guangyuan Key Lab Multifunct Med Hydrogel Guangyuan 628000 Peoples R China Nanjing Normal Univ Jiangsu Collaborat Innovat Ctr Biomed Funct Mat Sch Chem & Mat Sci Jiangsu Key Lab Biofunct Mat Nanjing 210023 Peoples R China Sichuan Univ Coll Polymer Sci & Engn State Key Lab Polymer Mat Engn Chengdu 610065 Peoples R China

Recent advances in the combined delivery platform that integrate nano-/microscale carriers and with 3D hydrogel network for bone regeneration are *** strategies for bioactive molecules delivery involving nanoparticles, nanosheets, and microspheres, along with extra stimuli such as near-infrared light, temperature changes, ultrasonication, and inflammatory conditions, are *** prospects and challenges for the clinical translation and the development of nano-/microscale incorporated hydrogel-based delivery platform are discussed. Bioactive molecules have shown great promise for effectively regulating various bone formation processes, rendering them attractive therapeutics for bone regeneration. However, the widespread application of bioactive molecules is limited by their low accumulation and short half-lives in vivo. Hydrogels have emerged as ideal carriers to address these challenges, offering the potential to prolong retention times at lesion sites, extend half-lives in vivo and mitigate side effects, avoid burst release, and promote adsorption under physiological conditions. This review systematically summarizes the recent advances in the development of bioactive molecule-loaded hydrogels for bone regeneration, encompassing applications in cranial defect repair, femoral defect repair, periodontal bone regeneration, and bone regeneration with underlying diseases. Additionally, this review discusses the current strategies aimed at improving the release profiles of bioactive molecules through stimuli-responsive delivery, carrier-assisted delivery, and sequential delivery. Finally, this review elucidates the existing challenges and future directions of hydrogel encapsulated bioactive molecules in the field of bone regeneration.

关键词： Hydrogel Bone regeneration Bioactive molecules Drug delivery Nano-/microscale carriers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental investigation and numerical analysis on high-efficiency shock vectoring control serpentine nozzles

引用

CHINESE JOURNAL OF AERONAUTICS 2024年第12期37卷 296-324页

作者： Hui, Zhonghao Shi, Jingwei Lin, Wentao Zhou, Li Wang, Zhanxue Liu, Yongquan Northwestern Polytech Univ Sch Power & Energy Xian 710072 Peoples R China Natl Key Lab Sci & Technol adv Light Duty Gas Turb Xian 710129 Peoples R China collaborat innovat ctr adv aeroengine Beijing 100191 Peoples R China

The high-efficiency Shock Vectoring Control Serpentine Nozzle (SVCSN) takes into account both thrust vectoring and infrared stealth, and significantly improves the comprehensive performance of the aero-engines through an additional auxiliary duct. In this paper, the schlieren photographs at the exit of the high-efficiency SVCSN and the wall static pressure distributions were obtained by experiments, and the numerical results were used to enrich the thrust vectoring characteristics. The effects of the auxiliary injection were analyzed first to reveal the advantages of the high-efficiency SVCSN compared to the conventional SVCSN. Then, the aerodynamic parameters and the structural parameters of the high-efficiency SVCSN were investigated, including the Nozzle Pressure Ratio (NPR), the Secondary flow Pressure Ratio (SPR), the secondary flow relative area and the secondary flow injection angle. Finally, the coupling performance of the high-efficiency SVCSN is studied by using the approximate modeling technology. Results show that the auxiliary injection increases the range between the two shock legs of the "k" shock wave induced by the secondary flow, then causes the separation zone and high-pressure boss of the down wall to expand upstream, and finally results in a prominent increase in the thrust vectoring performance. The thrust vectoring angle and Vectoring Efficiency (VE) of the high-efficiency SVCSN are about 61.6% and 75.7%, respectively, higher than those of the conventional SVCSN at NPR = 6. The effects of the NPR and the SPR on the thrust vectoring performance of the high-efficiency SVCSN are coupled with each other. A larger NPR matched with a smaller SPR shows better thrust vectoring performance. The maximum fluctuations in thrust vectoring angle and VE caused by the NPR and SPRare about 22% and 64%. The VE decreases monotonously with the increase of the secondary flow relative area. Smaller secondary flow injection angle shows better thrust vector performan

关键词： Shock vectoring control Serpentine nozzle Auxiliary injection Thrust vectoring performance Flow control

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flexible and resilient Co/TiO₂/SiOC nanofibers via electrospinning: Towards thermal and electromagnetic wave protection

引用

JOURNAL OF advANCED CERAMICS 2024年第10期13卷 1666-1676页

作者： Pan, Linghao Liu, Rui Meng, Fanqi Li, Zhonglin Hou, Yi Wang, Lixi Nanjing Tech Univ Coll Mat Sci & Engn Nanjing 211816 Peoples R China Jiangsu collaborat innovat ctr adv Inorgan Funct C Nanjing 211816 Peoples R China

Polymer-derived ceramic (PDC)-SiOC is a highly promising microwave-absorbing material characterized by high temperature resistance, lightweight, high strength, and extremely low cost. The weak electromagnetic wave (EMW) attenuation capacity and poor flexibility of single precursor-derived SiOC ceramics significantly limit their further application. This study employs a simple electrospinning technique to uniformly distribute Co and TiO2 within amorphous SiOC nanofibers. The three-dimensional porous structure formed by continuous nanofibers endows Co/TiO2/SiOCs with high porosity, significantly reducing the thermal conductivity and enhancing the conductive loss of electromagnetic waves within the nanofiber mats. Additionally, the introduction of Co and Ti promotes nanostructuring of the fibers and introduces polarization interfaces and defects, thereby enhancing the polarization loss of the samples. With a filler content of only 5 wt%, the Co/TiO2/SiOC sample heat-treated at 800 degrees C (in silicone resin) exhibits an effective absorption bandwidth (EAB) of up to 8.64 GHz (9.36-18.00 GHz) at a thickness of 3.25 mm, achieving a minimum reflection loss (RLmin) value of -66.00 dB at 17.11 GHz with a matching thickness of 2.50 mm. Moreover, the nanofiber mats also demonstrate excellent thermal insulation performance (thermal conductivity ranging m(-1)k(-1)), remarkable flexibility (the resistance change rate after 1500 cycles of 180 degrees bending test is less than 4%), and impressive resilience performance (residual strain < 12% after 500 cycles under 60% strain conditions). The successful preparation of such multi-functional nanofiber mats is promising for the application of thermal and microwave protection.

关键词： SiOC nanofibers electrospinning microwave absorption thermal insulation flexibility and resilience

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Understanding microwave dielectric properties of (1-x)CaTiO3-xLaAlO3 ceramics in terms of A/B-site ionic-parameters

引用

Journal of advanced Ceramics 2017年第1期6卷 20-26页

作者： Dou, Zhanming Wang, Gan Jiang, Juan Zhang, Fan Zhang, Tianjin Hubei Univ Minist Educ Hubei Collaborat Innovat Ctr Adv Organ Chem Mat Key Lab Green Preparat & Applicat Funct Mat Wuhan 430062 Peoples R China Hubei Univ Sch Mat Sci & Engn Wuhan 430062 Peoples R China

We prepared (1-x)CaTiO3-xLaAlO3 (0 ≤x≤ 1) microwave dielectric ceramics using a conventional two-step solid-state reaction method,and investigated microwave dielectric properties of the ceramics in terms of A/B-site ***-parameters such as ionic polarizability,A-site bond valence,and ionic rattling were linked to the microwave dielectric *** the LaAlO3 content x in the (1-x)CaTiO3-xLaAlO3 ceramics increased from 0.3 to 0.7,the dielectric constant gradually decreased,which was attributed to the decrease of polarizability deviation and suppression of the cation *** temperature coefficient of the resonant frequency decreased as the content of LaAlO3 increased because of the increase of A-site cation bond *** quality factor value (Q × f) increased as LaAlO3 content increased because of the enhancement of the order degree of B-site cation.A significant deterioration of the temperature coefficient of the resonant frequency and Q ×fvalue was observed at the composition x =*** decreases were attributed to a phase transition from orthorhombic crystal (for x ≤ 0.5) to rhombohedral crystal (for x ＞ 0.5).

关键词： (1-x)CaTiO3-xLaAlO3 (CTLA) microwave dielectric ceramics ionic polarizability bond valence cation rattling effect

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metal-organic framework loaded manganese oxides as efficient catalysts for low-temperature selective catalytic reduction of NO with NH3

引用

Frontiers of Chemical Science and Engineering 2017年第4期11卷 594-602页

作者： Zhang, Minhua Huang, Baojuan Jiang, Haoxi Chen, Yifei Tianjin Univ Key Lab Green Chem Technol Minist Educ R&D Ctr Petrochem Technol Tianjin 300072 Peoples R China collaborat innovat ctr Chem Sci & Engn Tianjin 300072 Peoples R China

A mild in-situ deposition method was used to fabricate Mn-based catalysts on a UiO-66 carder for the selective catalytic reduction of NO by NH3 （NH3-SCR）. The catalyst with 8.5 wt-% MnOx loading had the highest catalytic activity for NH3-SCR with a wide temperature window （100-290 C） for 90% NO conversion. Char- acterization of the prepared MnOx/UiO-66 catalysts showed that the catalysts had the crystal structure and porosity of the UiO-66 carrier and that the manganese particles were well-distributed on the surface of the catalyst. X-ray photoelectron spectroscopy analysis showed that there are strong interactions between the MnOx and the Zr oxide secondary building units of the UiO-66 which has a positive effect on the catalytic activity. The 8.5 wt-% MnOx catalyst maintained excellent activity during a 24-h stability test and exhibited good resistance to SO2 poisoning.

关键词： metal-organic framework selective catalyticreduction manganese oxides deNOx SO2 resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bimetallic Ni-Fe catalysts derived from layered double hydroxides for CO methanation from syngas

引用

Frontiers of Chemical Science and Engineering 2017年第4期11卷 613-623页

作者： Tang, Honggui Li, Shuangshuang Gong, Dandan Guan, Yi Liu, Yuan Tianjin Univ Sch Chem Engn Dept Catalysis Sci & Technol Tianjin 300072 Peoples R China Tianjin Univ Sch Chem Engn Collaborat Innovat Ctr Chem Sci & Engn Tianjin Tianjin 300072 Peoples R China

Carbon deposition and sintering of active components such as nano particles are great challenges for Ni-based catalysts for CO methanation to generate synthetic natural gas from syngas. Facing the challenges, bimetallic catalysts with different Fe content derived from layered double hydroxide containing Ni, Fe, Mg, A1 elements were prepared by co-precipitation method. Nanoparticles of Ni-Fe alloy were supported on mixed oxides of aluminium and magnesium after calcination and reduction. The catalysts were characterized by Brunner- Emmett-Teller （BET）, X-ray diffraction, hydrogen tem- perature programmed reduction, inductively coupled plasma, X-ray photoelectron spectroscopy, transmission electron microscopy and thermogravimetric techniques, and their catalytic activity for CO methanation was investigated. The results show that the Ni-Fe alloy catalysts exhibit better catalytic performance than mono- metallic catalysts except for the Ni4Fe-red catalyst. The Ni2Fe-red catalyst shows the highest CO conversion （100% at 260-350 ~C）, as well as the highest CH4 selectivity （over 95% at 280-350 ~C）, owing to the formation of Ni-Fe alloy. In stability test, the Ni2Fe-red catalyst exhibits great improvement in both anti-sintering and resistance to carbon formation compared with the Ni0Fe-red catalyst. The strong interaction between Ni and Fe element in alloy and surface distribution of Fe element not only inhibits the sintering ofnanoparticles but restrains the formation of Ni clusters.

关键词： methanation layered double hydroxide bime-tal Ni-Fe alloy sintering carbon deposition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Variations in summertime ozone in Nanjing between 2015 and 2020: roles of meteorology, radical chain length and ozone production efficiency

引用

FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING 2024年第11期18卷 137-137页

作者： Li, Lin Li, Jingyi Qin, Momei Xie, Xiaodong Hu, Jianlin Zhang, Yuqiang Nanjing Univ Informat Sci & Technol Collaborat Innovat Ctr Atmospher Environm & Equipm Jiangsu Key Lab Atmospher Environm Monitoring & Po Nanjing 210044 Peoples R China Shandong Univ Environm Res Inst Qingdao 266237 Peoples R China

Changes in ozone (O3) can be evaluated to inform policy effectiveness and develop reasonable emissions reduction measures. This study investigated the causes of summertime maximum daily 8-h average (MDA8) O3 variation between 2015 and 2020 in Nanjing, China, a megacity in the Yangtze River Delta (YRD) region, from the perspective of meteorological conditions and anthropogenic emissions of O3 precursors (VOCs and Nox). Compared with 2015, the observed MDA8 O3 decreased by 19.1 mu g/m3 in August 2020. The indirect and indirect impacts of meteorological conditions contributed 44% of the decline, with temperature, relative humidity, and wind playing important roles in the O3 variation. The O3 drop by 10.7 mu g/m3 (56% of the total decrease) may have been due to the decreases in anthropogenic emissions of VOCs and NOx by 7.8% and 11.7%, respectively. The longer hydroxyl (OH) radical chain length and higher ozone production efficiency (OPE) indicated that the reduction of anthropogenic emissions accelerated the ROx (ROx = OH + HO2 + RO2) and NOx cycles in O3 production, making O3 more sensitive to NOx. This corresponded to the O3 formation shifting from a VOC-limited regime in 2015 to a transition regime in 2020 and O3 decrease with anthropogenic emission reduction. Hence, the joint control of O3 precursor emissions can effectively mitigate O3 pollution in Nanjing.

关键词： Ozone Meteorological condition Anthropogenic emission OH radical chain length OPE

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flexible Mg_(3)N_(2)layer regulates lithium plating-striping for stable and high capacity lithium metal anodes

引用

Nano Research 2022年第9期15卷 8128-8135页

作者： Dong Ding Bo Zhang Lu Wang Jianmin Dou Yanjun Zhai Liqiang Xu Key Laboratory of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShandong UniversityJinan 250100China collaborat innovat ctr Chemn Energy Storage&Nove Shandong Prov Key LabLiaocheng UniversityLiaocheng 252000China

Lithium metal is regarded as one of the most promising candidates for next-generation ***,lithium dendrite formation and dead lithium accumulation are the critical problems which hinder its practical ***,we constructed a flexible coating membrane layer which could effectively uniform the lithium deposition by isolating lithium metal from electrolyte and regulating the ion flux *** modification,both the Li||Li symmetric cells(more than 1,400 h at 1 mA·cm^(−2)and 1 mAh·cm^(−2))and Li||Cu cells(more than 500 cycles at 0.5 mA·cm^(−2)and 0.5 mAh·cm^(−2),coulombic efficiency over 98%)deliver excellent long-cycle performance with high coulombic *** high performance is also proved in LiFePO4(capacity retention increases from 79%to 93%at 2 C after 400 cycles)and NCM811 full cells(capacity retention from 28.5%to 78%at 2 C after 500 cycles).High electro-performance in batteries demonstrates that the multifunctional layer plays a crucial role in stabilizing lithium ***,in order to verify the universality of the method,we have extended this facile way to fabricate other types of flexible *** work offers an insight into solving the current obstacles in the application of lithium metal batteries.

关键词： lithium metal battery Mg_(3)N_(2) solid electrolyte interphase(SEI) deposition flexible

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Electron microscopy studies of the coronavirus ribonucleoprotein complex

引用

Protein & Cell 2017年第3期8卷 219-224页

作者： Gui, Miao Liu, Xin Guo, Deyin Zhang, Zhen Yin, Chang-Cheng Chen, Yu Xiang, Ye Peking Univ Hlth Sci Ctr Sch Basic Med Sci Dept Biophys Beijing 100191 Peoples R China Tsinghua Univ Sch Med Dept Basic Med SciCtr Global Hlth & Infect Dis Beijing Adv Innovat Ctr Struct BiolCollaborat In Beijing 100084 Peoples R China Wuhan Univ Coll life Sci State Key Lab Virol Wuhan 430072 Peoples R China

Coronaviruses are enveloped viruses that cause different diseases in humans and animals （Suet al., 2016）. Murine hepatitis virus （MHV） causes hepatitis, enteritis and central nervous system diseases in rodents and is one of the best- studied coronaviruses. MHV belongs to the genera betacoronavirus. Members from the same genera also include highly pathogenic coronaviruses such as the severe acute respiratory syndrome coronavirus （SARS-CoV） and the Middle-East respiratory syndrome coronavirus （MERS-CoV）（Vijay and Perlman, 2016）.

关键词： studies microscopy Electron

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Preparation and characteristics of TEMPO-oxidized cellulose nanofibrils from bamboo pulp and their oxygen-barrier application in PLA films

引用

Frontiers of Chemical Science and Engineering 2017年第4期11卷 554-563页

作者： Wu, Bozhen Geng, Biyao Chen, Yufei Liu, Hongzhi Wu, Qiang Li, Guangyao Zhejiang Univ Technol Coll Mat Sci & Engn Hangzhou 310014 Zhejiang Peoples R China Zhejiang Prov collaborat innovat ctr Bamboo Resou Hangzhou 311300 Zhejiang Peoples R China Zhejiang Agr & Forestry Univ Sch Engn Hangzhou 311300 Zhejiang Peoples R China

Bleached bamboo kraft pulp was pretreated by 2,2,6,6-tetramethylpiperidine-l-oxy radical （TEMPO）- mediated oxidation using a TEMPO/NaBr/NaC10 system at pH = 10 in water to facilitate mechanical disintegration into TEMPO-oxidized cellulose nanofibrils （TO-CNs）. A series of TO-CNs with different carboxylate contents were obtained by varying amounts of added NaC10. An increase in carboxylate contents results in aqueous TO-CN dispersions with higher yield, zeta potential values, and optical transparency. When carboxylate groups are introduced, the DPv value of the TO-CNs remarkably decreases and then levels off. And the presence of hemicellulose in the pulp is favorable to TEMPO oxidization. After the oxidization, the native cellulose I crystalline structure and crystal size of bamboo pulp are almost maintained. TEM micrographs revealed that the degree of nanofibrillation is directly proportional to the carboxylate contents. With increasing carboxylate con- tents, the free-standing TO-CN films becomes more transparent and mechanically stronger. The oxygen permeability of PLA films drastically decreases from 355 for neat PLA to 8.4 mL-1 m a. d-1 after coating a thin layer of TO-CN with a carboxylate content of 1.8 mmol.g1. Therefore, inexpensive and abundant bamboo pulp would be a promising starting material to isolate cellulose nanfibrils for oxygen-barrier applications.

关键词： bamboo TEMPO cellulose nanofibrils oxy-gen barrier

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：