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Challenges and improvement in management of neonates born to mothers with COVID-19 in China

Frigid Zone Medicine 2022年第2期2卷 94-102页

作者： Jie Yang Zhuxiao Ren Lingkong Zeng Shiwen Xia Lin Wang Jiayu Miao Zhe Zhao Chuanzhong Yang Xiuyong Cheng Huayan Zhang Yuanfang Zhu Li Liu Xirong Gao Bin Yi Zhenlang Lin Wei Liu Xiaoyu Zhou Benqing Wu Ling Chen Zhankui Li Xuefeng Zhang Wei Lu Lianhong Zhang Xiao Chen Xiaoyun Zhong Falin Xu Jinhui Wu Yong Ji Jiahua Pan Yanxiang Chen Carine Ronsmans Zhichun Feng Department of Neonatology Guangdong Women and Children HospitalGuangzhou 510000China Department of Neonatology Wuhan Children’s HospitalTongji Medical CollegeHuazhong University of Science&TechnologyWuhan 430000China Department of Neonatology Hubei Women and Children HospitalWuhan 430000China Department of Neonatology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Department of Neonatology Seventh Medical CenterPeople’s Liberation Army General HospitalBeijing 100010China Department of Neonatology Affiliated Shenzhen Maternity&Child Healthcare HospitalSouthern Medical UniversityShenzhen 518000China Department of Neonatology the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China Division of Neonatology and Center for Newborn Care Guangzhou Women and Children’s HospitalGuangzhou 510000China Division of Neonatology Children’s Hospital of PhiladelphiaPhiladelphiaPennsylvania 19104United States Department of Obstetrics Shenzhen Baoan Women’s and Children’s HospitalJinan UniversityShenzhen 518000China Department of Neonatology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710000China Department of Neonatology Hunan Children's HospitalChangsha410000China Department of Neonatology Gansu Provincial Maternal and Child Health HospitalLanzhou 730000China Department of Neonatology Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325000China Department of Pediatrics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Neonatal Medical Centre Children's Hospital of Nanjing Medical UniversityNanjing 210000China Department of Neonatology The University of Chinese Academy of Science-Shenzhen HospitalShenzhen 518000China Department of Neonatology Northwest Women and Children's HospitalXi’an 730000China Department of Neonatology The Fifth Medical CenterPeople’s Liberation Army General HospitalBeijing 100010China Neonatal Intensive Care

Objective:China was the first country suffering from the SARS-CoV-2 pandemic and one of the countries with stringent mother-neonate isolation measure *** increasing evidence suggests that coronavirus disease 2019(COVID-19)should not be taken as an indication for formula feeding or isolation of the infant from the ***:We conducted a retrospective cohort study in 44 hospitals from 14 provinces in China to investigate the management of neonates whose mothers have confirmed or suspected *** addition,65 members of Chinese Neonatologist Association(CNA)were invited to give their comments and suggestions on the clinical management guidelines for high-risk ***:There were 121 neonates born to 118 mothers suspected with COVID-19 including 42 mothers with SARS-CoV-2 positive results and 76 mothers with SARS-CoV-2 negative *** neonates were born by caesarean section,isolated from their mothers immediately after birth and were *** neonates were positive for SARSCoV-2 at initial testing between 36 and 46 h after *** the confusion on the clinical management guidelines,58.78%of the newborns were put into isolation,32.22%were subject to PCR tests,and 5.16%and 2.75%received breastfeeding and vaccination,***:The clinical symptoms of neonates born to mothers with confirmed SARS-CoV-2 were mild,though five neonates might have been infected in utero or during *** the favorable outcomes of neonates born to COVID-confirmed mothers,full isolation may not be ***,separation of the mother and her newborn should be assessed on a case-by-case basis,considering local facilities and risk factors for adverse outcomes,such as prematurity and fetal distress.

关键词： coronavirus disease 2019 neonates pregnant women infection control

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