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A mediation system for continuous spatial queries on a unified schema using Apache Spark

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Big Earth Data 2024年第1期8卷 115-141页

作者： Thi Thu Trang Ngo François Pinet David Sarramia Myoung-Ah Kang universitéclermont Auvergne ISIMAAubièreFrance universitéclermont Auvergne INRAEUR TSCFClermont-FerrandFrance universitéclermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance

Recent advances in big and streaming data systems have enabled real-time analysis of data generated by Internet of Things(IoT)systems and sensors in various *** this context,many applications require integrating data from several heterogeneous sources,either stream or static *** such as Apache Spark are able to integrate and process large datasets from different ***,these frameworks are hard to use when the data sources are heterogeneous and *** address this issue,we propose a system based on mediation techniques for integrating stream and static data *** integration process of our system consists of three main steps:configuration,query expression and query *** the configuration step,an administrator designs a mediated schema and defines mapping between the mediated schema and local data *** the query expression step,users express queries using customized SQL grammar on the mediated ***,our system rewrites the query into an optimized Spark application and submits the application to a Spark *** results are continuously returned to *** experiments show that our optimizations can improve query execution time by up to one order of magnitude,making complex streaming and spatial data analysis more accessible.

关键词： Streaming data streaming data integration mediator geospatial data continuous queries

Rôles et vécus des pharmaciens d’officine dans les soins palliatifsàdomicile en France Role and Experience ofCommunity Pharmacists in Home Palliative Care in France

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Psycho-Oncologie 2024年第3期18卷 181-190页

作者： Isabelle Cuchet Michael Dambrun Axelle Van Lander ACCePPT LAPSCOUniversitéClermont AuvergneClermont-Ferrand63001France LAPSCO UniversitéClermont AuvergneClermont-Ferrand63001France ACCePPT UniversitéClermont AuvergneClermont-Ferrand63001France

The need for home palliative care is increasing in allWestern *** pharmacists are local professionals whose role in end-of-life care at home remains poorly *** aim of this study is to understand how community pharmacists see their role in end-of-life home care in France,and to analyze their experiences of this *** online questionnaire was distributed to community pharmacists working in France between December 2022 and March *** the 136 respondents to the questionnaire,87%had accompanied at least one patient at the end of life in the 3 months preceding the *** education(88%of respondents),psychological support for caregivers(85%of respondents),securing treatment(82%of respondents)and monitoring therapeutic compliance(80%of respondents)are the behaviors validated by the greatest number of *** majority of professionals surveyed had a positive overall experience of managing patients at the end of *** results pave the way for pharmacists to better support end-of-life patients at home.

关键词： Palliative care home community pharmacists end-of-life support

ON THE ASYMPTOTIC SPECTRUM OF A TRANSPORT OPERATOR WITH ELASTIC AND INELASTIC COLLISION OPERATORS

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Acta Mathematica Scientia 2020年第3期40卷 805-823页

作者： Abdul-Majeed AL-IZERI Khalid LATRACH universitéclermont Auvergne CNRSLMBPF-63000 Clermont-FerrandFrance

In this article,we investigate the spectral properties of a class of neutron transport operators involving elastic and inelastic collision operators introduced by Larsen and Zweifel[1].Our analysis is manly focused on the description of the asymptotic spectrum which is very useful in the study of the properties of the solution to Cauchy problem governed by such operators(when it exists).The last section of this work is devoted to the properties of the leading eigenvalue(when it exists).So,we discuss the irreducibility of the semigroups generated by these *** close this section by discussing the strict monotonicity of the leading eigenvalue with respect to the parameters of the operator.

关键词： Compactness properties transport operator abstract boundary conditions asymptotic spectrum irreducibility leading eigenvalue

Modelling of Electrical Conductivity of a Silver Plasma at Low Temperature

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Plasma Science and Technology 2016年第8期18卷 812-820页

作者： Pascal ANDRE William BUSSIERE Alain COULBOIS Jean-Louis GELET David ROCHETTE université clermont Auvergne LAEPT MERSEN 15 rue Jacques de Vaucanson

During the working of electrical fuses, inside the fuse element the silver ribbon first begins to melt, to vaporize and then a fuse arc appears between the two separated parts of the element. Second, the electrodes are struck and the burn-back phenomenon takes place. Usually, the silver ribbon is enclosed inside a cavity filled with silica sand. During the vaporization of the fuse element, one can consider that the volume is fixed so that the pressure increase appears to reach pressures higher than atmospheric pressure. Thus, in this paper two pressures, 1 atm and 10 atm, are considered. The electrical field inside the plasma can reach high values since the distance between the cathode surface and the anode surface varies with time. That is to say from zero cm to one cm order. So we consider various electrical fields： 102 V/m, 103 V/m, 5×103 V/m, 104 V/m at atmospheric pressure and 105 V/m at a pressure of 10 atm. This study is made in heavy species temperature range from 2,400 K to 10,000 K. To study the plasma created inside the electric fuse, we first need to determine some characteristics in order to justify some hypotheses. That is to say： are the classical approximations of the thermal plasmas physics justified？ In other words： plasma frequency, the ideality of the plasma, the Debye-Hückel approximation and the drift velocity versus thermal velocity. These characteristics and assumptions are discussed and commented on in this paper. Then, an evaluation of non-thermal equilibrium versus considered electrical fields is given. Finally, considering the high mobility of electrons, we evaluate the electrical conductivities.

关键词： electrical conductivity silver fuses non-ideal plasma Debye-Hiickelapproximation drift velocity thermal velocity thermal non-equilibrium electrical fields

Microbial markers in colorectal cancer detection and/or prognosis

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World Journal of Gastroenterology 2018年第22期24卷 2327-2347页

作者： Romain Villéger Amélie Lopès Julie Veziant Johan Gagnière Nicolas Barnich Elisabeth Billard Delphine Boucher Mathilde Bonnet université clermont Auvergne Research Biologics Sanofi R&D Chirurgie digestive Centre Hospitalier Universitaire université clermont Auvergne Institut Universitaire de Technologie de Clermont-Ferrand

Colorectal cancer(CRC) is the second leading cause of cancer worldwide. CRC is still associated with a poor prognosis among patients with advanced disease. On the contrary, due to its slow progression from detectable precancerous lesions, the prognosis for patients with early stages of CRC is encouraging. While most robust methods are invasive and costly, actual patient-friendly screening methods for CRC suffer of lack of sensitivity and specificity. Therefore, the development of sensitive, non-invasive and cost-effective methods for CRC detection and prognosis are necessary for increasing the chances of a cure. Beyond its beneficial functions for the host, increasing evidence suggests that the intestinal microbiota is a key factor associated with carcinogenesis. Many clinical studies have reported a disruption in the gut microbiota balance and an alteration in the faecal metabolome of CRC patients, suggesting the potential use of a microbialbased test as a non-invasive diagnostic and/or prognostic tool for CRC screening. This review aims to discuss the microbial signatures associated with CRC known to date, including dysbiosis and faecal metabolome alterations, andthe potential use of microbial variation markers for noninvasive early diagnosis and/or prognostic assessment of CRC and advanced adenomas. We will finally discuss the possible use of these markers as predicators for treatment response and their limitations.

关键词： Colorectal cancer microbiota F.nucleatum Colibactin-producing E.coli prognostic markers diagnostic markers dysbiosis

Formation of a 40 A DC Current Arc During the Opening of Silver Contacts

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Plasma Science and Technology 2014年第5期16卷 471-478页

作者： M'hammed ABBAOUI André LEFORT Erwann CARVOU Damien SALLAIS James Brian Alexander MITCHELL Noureddine BEN JEMAA clermont université Université d'AuvergneEA 3120LAEPTBP 10448F-63000 Clermont-FerrandFrance Equipe Contacts Electriques IPR(UMR CNRS 6251)Universite de Rennes 135042 Rennes CedexFrance

The erosion of silver contacts due to break arcs with length proportional to time and of variable duration has been measured by weighing the contacts following 5000 openings at a constant current equal to 40 *** experimental results show that,for arc durations shorter than 60 μs,the transfer of metal from the anode to the cathode occurs,but after passing this stage,when the two electrodes are separated by greater distances,each will display *** is the result of the diffusion of material outside the space between the two *** order to interpret these results,we have applied a classical model of the physical phenomena occurring at the root of the *** of the experimental results shows that for an arc duration of less than15 μs,no distinct cathode root is seen to exist,but beyond this,several spots appear gradually on the cathode for arc duration up to 50 μs,after which they merge into a single *** comparison between experiment results and theoretical interpretation is reasonable up to 60 μs.

关键词： arc root cathode spot anode spot erosion contacts current density

Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation

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World Journal of Gastroenterology 2014年第21期20卷 6560-6572页

作者： Jennifer Raisch Emmanuel Buc Mathilde Bonnet Pierre Sauvanet Emilie Vazeille Amélie de Vallée Pierre Déchelotte Claude Darcha Denis Pezet Richard Bonnet Marie-Agnès Bringer Arlette Darfeuille-Michaud clermont université UMR1071 Inserm/Ud’Auvergne and INRA USC201863000 Clermont-FerrandFrance Centre Hospitalier universitaire 63000 Clermont-FerrandFrance

AIM: To provide further insight into the characterization of mucosa-associated Escherichia coli (E. coli) isolated from the colonic mucosa of cancer patients.

关键词： B2 Escherichia coli Carcinoembryonic antigen-related cell adhesion molecule 6 Cell proliferation Colon cancer Polyketide synthase genomic island

Fast MATLAB assembly of FEM matrices in 2D and 3D using cell-array approach

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第2期7卷 167-186页

作者： Jonas Koko clermont universit´e Universit´e Blaise Pascal LIMOSBP 10448F-63000 Clermont-FerrandFrance CNRSUMR 6158LIMOSF-63173 AubiereFrance

We propose a MATLAB implementation of the P1 finite element method for the numerical solutions of the Poisson problem and the linear elasticity problem in two-dimensional(2D)and three-dimensional(3D).The code consists of vectorized(and short)assembling functions for the matrices(mass and stiffness)and the right-hand *** for the P1 finite element,the element mass matrix and right-hand side are simple,the implementation uses only the MATLAB function sparse on the elements *** the stiffness matrix,to obtain a MATLAB implementation close to the standard form,cell-arrays are used to store the gradients of the element basis *** assembling procedure can then use matrix/vector products on small size *** experiments show that our implementation is fast,scalable with respect to time,and outperforms existing vectorized MATLAB FEM codes.

关键词： MATLAB code vectorization finite element stiffness matrix mass matrix

Archaea and the human gut:New beginning of an old story

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World Journal of Gastroenterology 2014年第43期20卷 16062-16078页

作者： Nadia Gaci Guillaume Borrel William Tottey Paul William O’Toole Jean-Fran?ois Brugère EA-4678 CIDAM Clermont UniversitéUniversité d’AuvergneF-63000 Clermont-FerrandFrance School of Microbiology and Alimentary Pharmabiotic Centre University College CorkCorkIreland

Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in the breath and isolation of two methanogenic species belonging to the order Methanobacteriales, Methanobrevibacter smithii and Methanosphaera stadtmanae. During the last decade, diversity of archaea encountered in the human gastrointestinal tract (GIT) has been extended by sequence identification and culturing of new strains. Here we provide an updated census of the archaeal diversity associated with the human GIT and their possible role in the gut physiology and health. We particularly focus on the still poorly characterized 7th order of methanogens, the Methanomassiliicoccales, associated to aged population. While also largely distributed in non-GIT environments, our actual knowledge on this novel order of methanogens has been mainly revealed through GIT inhabitants. They enlarge the number of final electron acceptors of the gut metabolites to mono- di- and trimethylamine. Trimethylamine is exclusively a microbiota-derived product of nutrients (lecithin, choline, TMAO, L-carnitine) from normal diet, from which seems originate two diseases, trimethylaminuria (or Fish-Odor Syndrome) and cardiovascular disease through the proatherogenic property of its oxidized liver-derived form. This therefore supports interest on these methanogenic species and its use as archaebiotics, a term coined from the notion of archaea-derived probiotics.

关键词： Human gut microbiota Methanogens Methanomassiliicoccus Methanomethylophilus Trimethylaminuria Trimethylamine Methane Cardiovascular disease Archaebiotics Probiotics