检索结果-南通市图书馆

Hydrocephalus Secondary to Intraventricular Myxopapillary Ependymoma: Case Report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Neuroscience 2024年第3期14卷 85-91页

作者： Juan Carlos Ayala-Alvarez Onyekachi Emmanuel Anyagwa Fátima Gabriela Macías-Ortiz Oluwatoyin Adalia Dairo Courtney Storm Truebody Reza Badrnejad Aishwarya Bhuta Shashwat Sandeep Phade Srushti Kishor Jamdar Mostafa Yassin Vismaja Vijayan Neurology Department Hospital Civil Fray Antonio Alcalde Guadalajara Jalisco Mxico School of Medicine New Vision University Tbilisi Georgia

Ependymomas are a somewhat diverse category of glial tumors that often develop from the lining of the brain’s ventricles, or the spinal cord’s central canal. They make up 5% of all neuroepithelial tumors, 10% of paediatric brain tumors, and up to 33% of brain tumors in children under the age of three. Hydrocephalus is one of the complications, and it can be identified as progressive macrocephaly or increasing head circumference crossing percentiles, nausea, vomiting, poor appetite, irritability, and regression of developmental milestones.

关键词： Hydrocephalus Myxopapillary Ependymoma (MPE) Paediatrics Neurosurgery Glioma Intracranial Hypertension

Meningoencephalitis due to Listeria monocytogenes in a Young Immunocompetent Patient: Case Report with Literature Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2024年第1期14卷 213-219页

作者： Janette Alejandra Gamiño Gutierrez Gustavo Adolfo Hernández Valdez Arleth Anahí Montaño Gómez Jorge Morales Rojas Graciela Gaddy Robles Martinez Anahi Herrera Ruelas Alin Kaori Ferreyra Gudiño Jocelin Celeste Jurado Cardona Jimena Jexabeth Ibáñez Núñez Anahí Fierros Ramos Departmento de Neurocirugia Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara México Departamento de Medicina Interna ISSSTE Tepic General Hospital APP Tepic México

Meningoencephalitis secondary to Listeria monocytogenes (L. monocytogenes) mainly affects newborns, the elderly and immunocompromised people;there are extremely rare cases in which said infection occurs in immunocompetent individuals. We present the case of a young adult patient without immunocompromise, who developed meningoencephalitis due to L. monocytogenes;This case is exceptional, since it occurred in an individual outside the classic age group, in addition to not having risk factors, which is why it should be considered an atypical causal agent.

关键词： Meningitis Encephalitis Rhombencephalitis Listeria monocytogenes Immunocompetent

Exposure to ephedrine attenuates Th1/Th2 imbalance underlying OVA-induced asthma through airway epithelial cell-derived exo-somal lnc-TRPM2-AS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2024年第6期22卷 530-540页

作者： HU Yan WANG Mengqing XIE Jing JIAO Luojia DING Yi LUO Yinhe Department of Pediatrics The First Hospital of Hunan University of Chinese MedicineChangsha 410007China Hunan University of Chinese Medicine Changsha 410208China Department of Rehabilitation Medical CollegeChangsha Civil Affairs Vocational and Technical CollegeChangsha 410004Hunan ProvinceChina Teaching and Research Office of Chinese and Western Combination Hunan University of Chinese MedicineChangsha 410208China

Although various anti-inflammatory medications,such as ephedrine,are employed to manage cough-variant asthma,their underlying mechanisms are yet to be fully *** studies suggest that exosomes derived from airway epithelial cells(AECs)contain components like messenger RNAs(mRNAs),micro-RNAs(miRNAs),and long noncoding RNA(lncRNA),which play roles in the occurrence and progression of airway *** study investigates the influence of AEC-derived exosomes on the efficacy of ephedrine in treating cough-variant *** established a mouse model of asthma and measured airway resist-ance and serum inflammatory cell ***-time polymerase chain reaction(RT-qPCR),Western blotting,and enzyme-linked im-munosorbent assay(ELISA)analyses were used to assess gene and protein expression *** were isolated and *** immunoprecipitation(RIP)and RNA pull-down assays were conducted to examine the interaction between hnRNPA2B1 and *** the ovalbumin(OVA)-challenged mouse model,ephedrine treatment reduced inflammatory responses,air-way resistance,and Th1/Th2 cell *** from OVA-treated AECs showed elevated levels of lnc-TRPM2-AS1,which were diminished following ephedrine *** exosomal lnc-TRPM2-AS1 mediated the Th1/Th2 imbalance in CD4^(+)T cells,with its packaging into exosomes being facilitated by *** study unveils a novel mechanism by which ephedrine ameli-orates OVA-induced CD4^(+)T cell imbalance by suppressing AEC-derived exosomal *** findings could provide a theoretical framework for using ephedrine in asthma treatment.

关键词： Asthma Ephedrine Exosomal lnc-TRPM2-AS1 Th1/Th2 imbalance HnRNPA2B1 Airway epithelial cells

Portal Venous Thrombosis and Splenic Hemangioma, Secondary to Acute Pancreatitis: Case Report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Open Journal of Gastroenterology 2024年第1期14卷 11-17页

作者： Gustavo Adolfo Hernández Valdez Harvey Yair Zamora Veliz Estefany Gilberty Mendoza Verdin Quitzia Mayanim Rentería Fonseca Itzel Velázquez Viniegra Janette Alejandra Gamiño Gutierrez Diana Rita Velázquez Jimenez Florencio Favian Andrade Luis Fernando Baez Bustos Jorge Morales Rojas María Jacqueline Martínez Tejeda Graciela Gaddy Robles Martínez Juan Antonio Contreras Escamilla Departamento de Medicina Interna ISSSTE Tepic General Hospital APP Tepic Nayarit México General Surgery Department ISSSTE Tepic General Hospital APP Tepic Nayarit México hospital civil Fray Antonio Alcalde Guadalajara Jalisco México

We present an unusual case of portal vein thrombosis with a splanchnic hemangioma secondary to acute biliary pancreatitis. We report a 45-year-old patient, who has systemic arterial hypertension in treatment, was admitted for abdominal pain in the epigastrium, with irradiation to the right hypochondrium, accompanied by nausea and vomiting of 10 occasions of bile content, physical examination with pain in the right hypochondrium, Murphy positive. We have laboratory studies with a lipase of 788, so a diagnosis of pancreatitis is made with an etiology to be determined. The laboratories suggestive of acute biliary pancreatitis (lipase 788.71);an imaging study was subsequently performed (ultrasonography) with the result of stone in the common bile duct. A laparoscopy was performed with relative improvement, so he was discharged and returned 20 days after surgery due to abdominal pain of the same intensity in the left hypochondrium. Ending his hospitalization with a splenectomy for splenic hemangioma with portal vein thrombosis.

关键词： Pancreatitis Esplenic Hemangioma Esplenectomy Portal Vein Thrombosis Surgery

Finger-actuated wireless-charging wearable multifunctional sweatsensing system for levodopa and vitamin C

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第4期17卷 3096-3106页

作者： Qihong Ning Shaoqing Feng Qingwen Sun Ruoyao Yu Tangan Li Hao Xu Daxiang Cui Kan Wang School of Sensing Science and Engineering School of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityKey Laboratory of Thin Film and Microfabrication Technology(Ministry of Education)Shanghai 200240China Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China School of Naval Architecture Ocean&Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China

Efficient portable wearable sweat sensors allow the long-term monitoring of changes in the status of biomarkers in sweat,which can be useful in diagnosis,medication,and nutritional *** this study,we designed and tested a wireless,battery-free,flexible,self-pumping sweat-sensing system that simultaneously tracks levodopa and vitamin C levels in human sweat and detects body *** system includes a microfluidic chip with a self-driven pump and anti-reflux valve,a flexible wireless circuit board,and a purpose-designed smartphone *** microfluidic chip is used for the efficient collection of sweat and the drainage of excess *** dual electrochemical sensing electrodes in the chip are modified with functional materials and appropriate enzymatic reagents,achieving excellent selectivity and *** sensitivities of the levodopa sensor and the vitamin C sensor are 0.0073 and 0.0018μA·μM^(-1),respectively,and the detection correlation coefficients of both exceed *** sensors have a wide linear detection range of 0–100 and 0–1000μM,respectively,and low detection limits of 0.28 and 17.9μM,*** flexible wireless circuit board is equipped with the functions of wireless charging,electrical signal capture and processing,and wireless *** data recorded from each sensor are displayed on a smartphone via a self-developed app.A series of experimental results confirmed the reliability of the sweat-sensing system in noninvasively monitoring important biomarkers in the human body and its potential utility in the comprehensive assessment of biological health.

关键词： self-pumping microfluidic channel wireless charging wearable sensor health monitoring

MIL-100(V) derived porous vanadium oxide/carbon microspheres with oxygen defects and intercalated water molecules as high-performance cathode for aqueous zinc ion battery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第3期90卷 578-589,I0013页

作者： Yuexin Liu Jian Huang Xiaoyu Li Jiajia Li Jinhu Yang Kefeng Cai Shanghai Key Laboratory of Development and Application for Metal-Functional Materials Key Laboratory of Advanced Civil Engineering MaterialsMinistry of EducationSchool of Materials Science&EngineeringTongji UniversityShanghai 201804China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 201800China Research Center for Translational Medicine East HospitalTongji University School of MedicineShanghai 200092China

The development of aqueous zinc ion battery cathode materials with high capacity and high magnification is still a ***,porous vanadium oxide/carbon(p-VO_(x)@C,mainly VO_(2) with a small amount of V_(2)O_(3)) core/shell microspheres with oxygen vacancies are facilely fabricated by using a vanadium-based metal-organic framework(MIL-100(V)) as a sacrificial *** unique structure can improve the conductivity of the VO_(x),accelerate electrolyte diffusion,and suppress structural collapse during ***,H_(2)O molecules are introduced into the interlayer of VO_(x) through a highly efficient in-situ electrochemical activation process,facilitating the intercalation and diffusion of zinc *** the activation,an optimal sample exhibits a high specific capacity of 464.3 mA h g^(-1) at0.2 A g^(-1) and 395.2 mA h g^(-1) at 10 A g^(-1),indicating excellent rate ***,the optimal sample maintains a capacity retention of about 89.3% after 2500 cycles at 10 A g^(-1).Density functional theory calculation demonstrates that the presence of oxygen vacancies and intercalated water molecules can significantly reduce the diffusion barrier for zinc *** addition,it is proved that the storage of zinc ions in the cathode is achieved by reversible intercalation/extraction during the charge and discharge process through various ex-situ analysis *** work demonstrates that the p-VO_(x)@C has great potential for applications in aqueous ZIBs after electrochemical activation.

关键词： Metal-organic frameworks Vanadium oxide Carbon Zn-ion batteries Electrochemical activation

Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicine

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2024年第4期16卷 410-433页

作者： Shafiqa Naeem Rajput Bushra Kiran Naeem Anwar Ali Asmat Salim Irfan Khan Dr.Panjwani Center for Molecular Medicine and Drug Research International Center for Chemical and Biological SciencesUniversity of KarachiKarachi 75270SindhPakistan Surgical Unit 4 Dr.Ruth KM Pfau Civil HospitalKarachi 74400Pakistan Department of Physiology University of KarachiKarachi 75270Pakistan Center for Regenerative Medicine and Stem Cells Research and Department of Ophthalmology and Visual SciencesThe Aga Khan UniversityKarachi 74800SindhPakistan

BACKGROUND Stem cells are undifferentiated cells that possess the potential for self-renewal with the capacity to differentiate into multiple *** humans,their limited numbers pose a challenge in fulfilling the necessary demands for the regeneration and repair of damaged tissues or *** suggested that mesenchymal stem cells(MSCs),necessary for repair and regeneration via transplantation,require doses ranging from 10 to 400 million ***,the limited expansion of MSCs restricts their therapeutic *** To optimize a novel protocol to achieve qualitative and quantitative expansion of MSCs to reach the targeted number of cells for cellular transplantation and minimize the limitations in stem cell therapy *** Human umbilical cord(hUC)tissue derived MSCs were obtained and *** cultured cells were subjected to the following evaluation pro-cedures:Immunophenotyping,immunocytochemical staining,trilineage differentiation,population doubling time and number,gene expression markers for proliferation,cell cycle progression,senescence-associatedβ-galactosidase assay,human telomerase reverse transcriptase(hTERT)expression,mycoplasma,cytomegalovirus and endotoxin *** Analysis of pluripotent gene markers Oct4,Sox2,and Nanog in recultured hUC-MSC revealed no significant *** immunophenotypic markers CD90,CD73,CD105,CD44,vimentin,CD29,Stro-1,and Lin28 were positively expressed by these recultured expanded MSCs,and were found negative for CD34,CD11b,CD19,CD45,and *** recultured hUC-MSC population continued to expand through passage *** gene expression of Pax6,BMP2,and TGFb1 showed no significant variation between recultured hUC-MSC ***,a significant increase(P<0.001)in the mitotic phase of the cell cycle was observed in recultured *** senescence markers(hTERT expression andβ-galactosidase activity)did not show any negative effect on recultured hUC-

关键词： Human umbilical cord Mesenchymal stem cells Expansion Cell proliferation In vitro expansion Senescence

Numerical Study of the Biomechanical Behavior of a 3D Printed Polymer Esophageal Stent in the Esophagus by BP Neural Network Algorithm

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第3期138卷 2709-2725页

作者： Guilin Wu Shenghua Huang Tingting Liu Zhuoni Yang Yuesong Wu Guihong Wei Peng Yu Qilin Zhang Jun Feng Bo Zeng College of civil Engineering and Architecture Key Laboratory of Disaster Prevention and Structural Safety of Ministry of EducationGuangxi Key Laboratory of Disaster Prevention and Structural SafetyScientific Research Center of Engineering MechanicsGuangxi UniversityNanning530004China Anaesthesiology Department of the 923th The 923th Hospital of PLA Joint Logistic Support ForceNanning530021China Biomedical Materials Engineering Research Center Tsinghua Innovation Center in DongguanDongguan523808China Research Centre Guangxi Nanning Ruifeng Medical Devices Co.Ltd.Nanning530000China Department of Thoracic Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhou510080China

Esophageal disease is a common disorder of the digestive system that can severely affect the quality of life andprognosis of patients. Esophageal stenting is an effective treatment that has been widely used in clinical ***, esophageal stents of different types and parameters have varying adaptability and effectiveness forpatients, and they need to be individually selected according to the patient’s specific situation. The purposeof this study was to provide a reference for clinical doctors to choose suitable esophageal stents. We used 3Dprinting technology to fabricate esophageal stents with different ratios of thermoplastic polyurethane (TPU)/(Poly-ε-caprolactone) PCL polymer, and established an artificial neural network model that could predict the radial forceof esophageal stents based on the content of TPU, PCL and print parameter. We selected three optimal ratios formechanical performance tests and evaluated the biomechanical effects of different ratios of stents on esophagealimplantation, swallowing, and stent migration processes through finite element numerical simulation and in vitrosimulation tests. The results showed that different ratios of polymer stents had different mechanical properties,affecting the effectiveness of stent expansion treatment and the possibility of postoperative complications of stentimplantation.

关键词： Finite element method 3D printing polymer esophageal stent artificial neural network

Periodontal disease:A silent factor in the development and progression of diabetic retinopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第8期15卷 1672-1676页

作者： Sarah Monserrat LomelíMartínez Irán Cortés Trujillo Melissa Martínez Nieto Ana Esther Mercado González Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810Mexico Master of Public Health Department of Wellbeing and SustainableCentro Universitario del NorteUniversidad de GuadalajaraColotlán 46200Mexico Periodontics Program Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico Antiguo hospital civil de Guadalajara“Fray Antonio Alcalde” Guadalajara 44280Mexico

The global increase in the prevalence of type 2 diabetes mellitus(T2DM)and its complications presents significant challenges to public ***,periodontal disease(PD)was recognized as a factor that is likely to influence the progression of T2DM and its complications due to its potential to exacerbate systemic inflammation and oxidative *** this editorial,we comment on the article published by Thazhe Poyil et al in the very recent issue of the World Journal of Diabetes in 2024,which investigated the correlation between PD and diabetic retinopathy(DR)in T2DM patients,with emphasis on the association between periodontal swollen surface area,glycated hemoglobin(HbA1c),interleukin-6(IL-6),and lipoprotein(a).The findings by Thazhe Poyil et al are significant as they demonstrate a strong link between PD and DR in T2DM *** correlation highlights the importance of addressing periodontal health in diabetes management to potentially reduce the risk and severity of DR,a complication of *** integration of periodontal evaluation and treatment into diabetes care protocols may lead to improved glycemic control and better overall outcomes for T2DM patients.A few studies have established an interconnection between PD and diabetic complication,specifically DR,in T2DM patients,which we aim to highlight in this *** was placed on the different mechanisms that suggest a bidirectional relationship between PD and T2DM,where the presence of periodontal inflammation negatively influenced glycemic control and contributed to the development and progression of DR through shared inflammatory and vascular *** article highlights the importance of collaboration amongst diabetes specialists,ophthalmologists,periodontists,and public health professionals to advance the prevention,early detection,and treatment of PD and *** will improve the health and quality of life of T2DM ***,the editorial highlights the need for further re

关键词： Type 2 diabetes mellitus Periodontal disease Periodontitis Diabetic retinopathy Editorial