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5mg和10mg利扎曲普坦片与25mg和50mg舒马曲坦片对偏头痛疗效的比较研究

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世界核心医学期刊文摘（神经病学分册） 2005年第2期1卷 10-10页

作者： Polis A. Battisti W.P. F. Skobieranda 黄卫东 Merck and Co. Inc. HM 222 PO Box 4 West Point PA 19 486 United States Dr.

This randomized, double blind, two attack, placebo controlled, crossover st udy explored the efficacy and tolerability of rizatriptan 10 mg compared with su matriptan 50 mg as well as rizatriptan 5 mg compared with sumatriptan 25 mg in t he acute treatment of migraine. Following randomization to one of six possible t reatment sequences, patients (n=1447) treated two sequential attacks, of moderat e or severe intensity, separated by at least 5 days. Patients assessed pain seve rity, migraine asso ciated symptoms, and functional disability at 0.5, 1, 1.5, and 2 h post treatment. Compared with placebo, all treatments were effective. O n the primary endpoint of time to pain relief, rizatriptan 10 mg was not statist ically different from sumatriptan 50 mg [odds ratio (OR) 1.10, P = 0.161], and r izatriptan 5 mg was statistically superior to sumatriptan 25 mg (OR 1.22, P=0.00 7). In general, rizatriptan 10 mg and 5 mg treatment resulted in improvement com pared with the corresponding doses of sumatriptan on measures of pain severity, migraine symptoms, and functional disability and the 5 mg dose reached statisti cal significance on almost all measures. All treatments were generally well tole rated.

关键词： mg 舒马曲坦患者耐受性安慰剂对照中间间隔疼痛缓解时间功能障碍交叉试验

固体润滑滚动轴承—第五部分:汽轮发动机用高速高温轴承的发展

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固体润滑 1987年第4期 236-246页

作者： C.R.Meeks M.W.Eusepi 李玉梅 Hughes Aircraft Company EL Segundo California Mechanical Technology inc Latham New York

应用三种互相促进的研究方法研制了高温(316℃)、高速(40000～50000r/min)固体润滑轴承。为了得到可在恶劣环境中使用的最优设计的轴承,同时应用了基本材料科学研究、计算机辅助设计和组件检验等方法。在40000r/min的条件下,轴承的性能... 详细信息

应用三种互相促进的研究方法研制了高温(316℃)、高速(40000～50000r/min)固体润滑轴承。为了得到可在恶劣环境中使用的最优设计的轴承,同时应用了基本材料科学研究、计算机辅助设计和组件检验等方法。在40000r/min的条件下,轴承的性能从3分钟提高到38分钟。所有轴承的失效都是由于球与兜孔严重磨损而引起球保持器的结构失效或间隙被闭合。用层状过渡金属二硫属化合物填充的石墨复合材料的球保持器、溅射二硫化钼的钢座圈和烧结碳化硅球得到的性能最好。

关键词：保持器复合材料轴承兜孔座圈发动机

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炉缸内衬设计的考虑

炼铁 1991年第2期10卷 44-44页

作者： A.J.Dzermejko UCAR Carbon Compang inc

本文从探讨炉缸内衬磨损机理出发,阐述了正确的炉缸内衬设计的种种考虑,介绍了NMA专利热压炭砖的优良性能和使用情况。

关键词：高炉炉缸内衬设计 NMA炭砖

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不同限幅类型下的相位编码波形的检测性能

现代雷达 1991年第1期13卷 26-38页

作者： F.R.Castella S.A.Rudie 韦传安 Applied Physics Laboratory The John Hopkins University G.P.Taurio inc 美国

本文针对三种接收机限幅类型,计算了相位编码雷达波形的检测性能并将其与没有限幅时的结果作了比较。损失(以dB表示),即有与没有限幅时检测所需要的信号噪声比之差,是要求的检测概率P_d、虚警概率P_(fa)、目标的雷达截面积起伏模型、脉... 详细信息

本文针对三种接收机限幅类型,计算了相位编码雷达波形的检测性能并将其与没有限幅时的结果作了比较。损失(以dB表示),即有与没有限幅时检测所需要的信号噪声比之差,是要求的检测概率P_d、虚警概率P_(fa)、目标的雷达截面积起伏模型、脉冲编码长度Nc以及检测前的非相参积累脉冲数M_p的函数。对一个给定的P_(fa)用分析法来确定检测门限,并用Monte Carlo方法来仿真检测过程。在所研究的三种方法中,损失最小的限幅方法是把信号加噪声的I和O正交分量量化为3位,而把其中的2位分配给噪声幅度。损失较大的情况是硬限幅,也即只保留相位的情况,这时信号的相位信息被保留,但是幅度信息却没有利用。损失最大的情况是相位被量化为4个数值的硬限幅。

关键词：雷达波形检测相位编码接收机

Propagation and Dispersion Characteristics of Scholte Wave in VTI Media with the Presence of Irregular Seabed

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Journal of Earth Science 2024年第2期35卷 722-725页

作者： Xiaobo Liu Yun Wang Jianlei Zhang Haifeng Chen Hua Zhang School of Ocean Sciences China University of GeosciencesBeijing 100083China Key Laboratory of Polar Geology and Marine Mineral Resources China University of GeosciencesBeijing 100083China School of Geophysics and Information Technology China University of GeosciencesBeijing 100083China Research&Development Center BGP IncCNPCZhuozhou 072751China National Engineering Research Center for Oil and Gas Exploration Computer Software Beijing 100080China

INTRODUCTION Surface waves propagating along the seafloor are general ly called Scholte waves,and were first discovered and studied in the early 1950s(Kugler et al.,2005;Buchen and Ben-Hador,1996).Scholte waves exhibit a dispersion phenomenon,which implies that their velocity varies with ***-frequency Scholte waves can propagate over long distances on the seabed with little attenuation(Bohlen et al.,2004).The particle mo tion of Scholte waves in a solid medium changes from a retro grade to a prograde ellipse(Klein et al.,2005;McMechan and Yedlin,1981).

关键词： seabed Dispersion implies

Erratum to: TfRl Extensively Regulates the Expression of Genes Associated with Ion Transport and Immunity

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Current Medical Science 2020年第5期40卷 998-998页

作者： Nan HUANG Lei-lei ZHAN Yi CHENG Xiao-long WANG Ya-xun WEI Qi WANG Wen-jing LI Department of Allergy Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Center.for Genome Analysis ABLife Inc.Wuhan 430075China Department of Oncology Tongji HospitalTongi Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

It is hereby certified that there is no shared co-first authorship in this *** HUANG is the only first author of this article.

关键词： HUANG certified Associated

大容量系统用纠双错Reed-Solomon速算法及其VLSI实现

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半导体技术 2005年第2期30卷 58-62,69页

作者：楼向雄骆建军邓先灿浙江大学信息与电子工程学系 Baleen System inc.20823 Stevens Creek Blvd 110 Cupertino CA USA 95014

提出了一种适用于大容量(Mass-Storage)系统可纠双错的Reed-Solomon快速编、泽码算法,具有硬件实现代价小,运算速度快的优点。该电路设计已成功地应用于大容量片上系统(SOC)芯片中,该芯片采用台机电TSMC的0.25 μm的工艺实现,直接验证... 详细信息

提出了一种适用于大容量(Mass-Storage)系统可纠双错的Reed-Solomon快速编、泽码算法,具有硬件实现代价小,运算速度快的优点。该电路设计已成功地应用于大容量片上系统(SOC)芯片中,该芯片采用台机电TSMC的0.25 μm的工艺实现,直接验证了本文的理论成果。

关键词： Reed-Solomon算法差错控制编码大容量存储片上系统

Efficacy and safety of abrocitinib in Chinese patients with moderate-to-severe atopic dermatitis:A post hoc analysis of the JADE REGIMEN phase 3 trial

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Chinese Medical Journal 2024年第16期137卷 1991-1992页

作者： Hang Li Hao Cheng Qianjin Lu Wei Lai Xiaohua Tao Gerardo AEncinas Shefali Vyas Bo Wang Xin Luo Shiqi Li Department of Dermatology Peking University First HospitalNational Clinical Research Center for Skin and Immune DiseasesBeijing 100034China Department of Dermatology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiang 310016China Department of Dermatology The Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China Department of Dermatology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China Department of Dermatology Zhejiang Provincial People’s HospitalHangzhou Medical CollegeHangzhouZhejiang 310014China Pfizer S.A.de C.V. Mexico CityMexico Pfizer inc. New YorkNYUSA Pfizer Investment Co. LtdBeijing 100010China Pfizer(China)R&D Co. LtdShanghai 201200China Pfizer PBG Shanghai 200041China

To the Editor:Atopic dermatitis(AD)is a chronic inflammatory skin disorder with a relapsing-remitting disease course that warrants flexible dosing.[1,2]In China,abrocitinib,an oral,once-daily,Janus kinase 1-selective inhibitor,is approved at a 100 mg starting dose for adults with refractory moderate-to-severe AD who did not inadequately respond to other systemic therapies(i.e.,corticosteroids or biologics),or for whom these treatments are not *** the response achieved with abrocitinib 100 mg is inadequate,200 mg dosing can be considered,which could be administered as a short-term treatment(≤12 weeks).[3]The phase 3 JADE REGIMEN trial(***,NCT03627767)evaluated maintenance of response with continuous-dose abrocitinib(200 mg),reduced-dose abrocitinib(100 mg),or drug withdrawal(placebo)in patients with moderate-to-severe AD who responded to abrocitinib induction therapy.[4]Here,we aimed to characterize the efficacy and safety of abrocitinib in the Chinese mainland subgroup within JADE REGIMEN.

关键词： dermatitis patients JADE

Evaluating chromosomal segregation in a family where both spouses carry an autosomal translocation

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Reproductive and Developmental Medicine 2023年第3期7卷 189-192页

作者： Irina L.Puppo Ziravard N.Tonyan Alsu F.Saifitdinova Julia A.Loginova Anna A.Kinunen Alisa N.Panina Julia R.Pastuhova Olga A.Leonteva Olga G.Chiryaeva Olga V.Malysheva Oleg S.Glotov Irina V.Poliakova Andrey V.Tikhonove Tatyana V.Vavilova Irina L.Menshikova Elvira V.Isakova Andrey S.Glotov Natalya K.Bichevaya International Centre for Reproductive Medicine Saint-Petersburg 197350Russia Department of Laboratory Medicine and Genetics Almazov National Medical Research CentreSaint-Petersburg197341Russia Department of Genomic Medicine D.O.Ott's Institute of ObstetricsGynecologyand ReproductologySaint-Petersburg 199034Russia Department of Biology.Herzen State Pedagogical University of Russia Saint-Petersburg 191186Russia DiaCarta Inc.2600 Hilltop DriveRichmondCA 94806 St.Petersburg Centre for Medical Genetics Saint Petersburg194044Russia Department of ExperimentalMedical Virology MolecularGenetics and Biobankingof Pediatric Researchand Clinical Center for Infectious DiseasesSaint-Petersburg 197022Russia Medical institute of Surgut State University Surgut 628403 Russia CerbaLab Ltd. Saint-Petersburg 199106Russia

Autosomal reciprocal translocations represent exchanges of chromatin fragments between non-homologous *** are facilitated by the creation of quadrivalent structures during the first meiotic division,which are characterized by the length of the translocated and centric segments,asymmetry,and the presence of terminal breakpoints,all of which may impact segregation ***,we report a rare case of multiple reciprocal translocations within a single *** inc.udes the evaluation of the translocations in each of the spouses and an analysis of their chromosome segregation patterns as determined by the constellation of universal characteristics in each of their *** obtained results will be of interest to fundamental biology,as they will expand the understanding of the factors affecting chromosome segregation during meiosis.

关键词： Embryo viability Genetic counseling Pre-implantation genetic testing Quadrivalent characteristics