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Food science and Human Wellness 2024年第5期13卷 2480-2501页

作者： Yanxi Li Longgao Xiao Huan Yan Mingyi Wu Xiaojiang Hao Haiyang Liu State Key Laboratory of Phytochemistry and plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China University of Chinese Academy of sciences Beijing 100049China Yunnan Characteristic plant Extraction Laboratory Kunming 650106China

Portulaca oleracea L.,commonly known as purslane,is a worldwide weed species belonging to the family Portulacaceae and has been known as“Global Panacea”.As one of the most widely consumed green vegetables and medicinal plants around the world,it has recently been re-evaluated as a potential“new crop”due to the properties that differentiate it as one of the best vegetable sources of omega-3 fatty acid(α-linolenic acid),as well as a variety of nutrients and ***,emerging research has found that purslane exhibits health-promoting properties like anti-inflammatory,anti-hyperglycemic,antioxidant,neuroprotective,and *** findings suggest that this species possesses a potential using as a dietary supplement beyond potherb and traditional *** review systematically summarizes the up-to-date research carried out on purslane,including the nutritional compositions,bioactive compounds,and health benefits it exerts as well as limitations,challenges,and future directions of ***,we hope that this review would provide purslane with a comprehensive reference and future scope as functional and health-promoting food for disease prevention and treatment.

关键词： Purslane Nutritional compositions Bioactive compounds Polysaccharides Functional foods

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Can perfluorooctanoic acid be effectively degraded usingβ-PbO_(2)reactive electrochemical membrane?

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Chinese Chemical Letters 2024年第7期35卷 196-199页

作者： Xubin Qian Lei Xu Xu Ge Zhun Liu Cheng Fang Jianbing Wang Junfeng Niu College of Environmental science and Engineering North China Electric Power UniversityBeijing 102206China College of Water Resources and Hydropower Engineering North China Electric Power UniversityBeijing 102206China research center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan 523808China Global Centre for Environmental Remediation(GCER) University of NewcastleCallaghanNSW 2308Australia School of Chemical and Environmental Engineering China University of Mining and Technology(Beijing)Beijing 100083China

Aqueous perfluorooctanoic acid(PFOA)elimination has raised significant concerns due to its persistence and ***β-PbO_(2)plate anodes have shown efficient mineralization of PFOA,it remains unclear whether PFOA can be effectively degraded usingβ-PbO_(2)reactive electrochemical membrane(REM).Herein,we assessed the performance of Ti/SnO_(2)-Sb/La-PbO_(2)REM for PFOA removal and proposed a possible degradation *** a current density of 10 mA/cm2and a membrane flux of 8500(liters per square meter per hour,LMH),the degradation efficiency of 10 mg/L PFOA was merely8.8%,whereas the degradation efficiency of 0.1 mg/L PFOA increased to 96.6%.Although the porous structure of theβ-PbO_(2)REM provided numerous electroactive sites for PFOA,the generated oxygen bubbles in the pores could block the pore channels and adsorb PFOA *** hindered the protonation process and significantly impeded the degradation of high-concentration *** experiments indicated that·OH played dominant role in PFOA *** electrical energy per order to remove 0.1 mg/L PFOA was merely 0.74 Wh/L,which was almost an order of magnitude lower than that of other anode *** study presents fresh opportunities for the electrochemical degradation of low-concentration PFOA usingβ-PbO_(2)REM.

关键词： Perfluorooctanoic acid β-PbO_(2) Reactive electrochemical membrane Electrochemical oxidation

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HIV encephalopathy is contributed by macrophages and microglia

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science China(Life sciences) 2024年第4期67卷 836-838页

作者： Si-Meng Liu Man Li Chunhui Ma Chunying Liu An Lv Qing Li Yamei Niu Peng Wang Bo Huang Wei-Min Tong Department of Pathology China Medical UniversityShenyang 110122China Department of Pathology Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeNeuroscience CenterChinese Academy of Medical SciencesBeijing 100005China Department of Pathology Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Molecular Pathology research center Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China center For Experimental Animal research Institute of Basic Medical SciencesChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100005China Department of Immunology and National Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100010China Department of Biochemistry and Molecular Biology Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Dear Editor,Acquired immunodeficiency syndrome(AIDS),characterized by a significant decrease in the number of CD4^(+)T cells,causes a defective T cell immune response,which subsequently leads to various conditional pathogenic infections and tumors(Calmy et al.,2018;Seligmann et al.,1987).Neurological disorders have been reported in 70%–80%of patients with AIDS(Saylor et al.,2016)。

关键词： encephalopathy immunodeficiency

Metabolic profiles and morphological characteristics of leaf tips among different sweet potato(Ipomoea batatas Lam.)varieties

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Journal of Integrative Agriculture 2024年第2期23卷 494-510页

作者： Wenqing Tan Xinbo Guo Zhangying Wang Rong Zhang Chaochen Tang Bingzhi Jiang Ruixue Jia Yuanyuan Deng Shaohai Yang Jingyi Chen Crops research Institute Guangdong Academy of Agricultural Sciences/Key Laboratory of Crop Genetic Improvement of Guangdong ProvinceGuangzhou 510640China School of Food science and Engineering South China University of TechnologyGuangzhou 510640China Sericultural&Agri-Food research Institute Guangdong Academy of Agricultural Sciences/Key Laboratory of Functional FoodsMinistry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products ProcessingGuangzhou 510610China

Sweet potato leaf tips have high nutritional value,and exploring the differences in the metabolic profiles of leaf tips among different sweet potato varieties can provide information to improve their *** this study,a UPLC-Q-Exactive Orbitrap/MS-based untargeted metabolomics method was used to evaluate the metabolites in leaf tips of 32 sweet potato *** varieties with distinct overall metabolic profiles(A01,A02,and A03),two varieties with distinct profiles of phenolic acids(A20 and A18),and three varieties with distinct profiles of flavonoids(A05,A12,and A16)were *** addition,a total of 163 and 29 differentially expressed metabolites correlated with the color and leaf shape of sweet potato leaf tips,respectively,were identified through morphological *** comparison analysis of the phenotypic traits and a metabolite-phenotypic trait correlation analysis indicated that the color differences of sweet potato leaf tips were markedly associated with ***,the level of polyphenols was correlated with the leaf shape of sweet potato leaf tips,with lobed leaf types having higher levels of polyphenols than the entire leaf *** findings on the metabolic profiles and differentially expressed metabolites associated with the morphology of sweet potato leaf tips can provide useful information for breeding sweet potato varieties with higher nutritional value.

关键词： sweet potato leaf tips phenotypic traits metabolic profile differentially expressed metabolites polyphenols

Trogocytosis of CAR molecule regulates CAR-T cell dysfunction and tumor antigen escape

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Signal Transduction and Targeted Therapy 2024年第1期9卷 326-337页

作者： You Zhai Yicong Du Guanzhang Li Mingchen Yu Huimin Hu Changqing Pan Di Wang Zhongfang Shi Xu Yan Xuesong Li Tao Jiang Wei Zhang Department of Molecular Neuropathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingPR China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijingPR China Department of Urology Peking University First HospitalInstitute of UrologyPeking UniversityNational Urological Cancer CenterBeijingPR China Department of Pathophysiology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingPR China China National Clinical research center for Neurological Diseases BeijingPR China center of Brain Tumor Beijing Institute for Brain DisordersBeijingPR China research Unit of Accurate Diagnosis Treatmentand Translational Medicine of Brain TumorsChinese Academy of Medical SciencesBeijingPR China Chinese Glioma Genome Atlas Network(CGGA)and Asian Glioma Genome Atlas Network(AGGA) BeijingPR China

Chimeric antigen receptor(CAR)T-cell therapy has demonstrated clinical response in treating both hematologic malignancies and solid *** instances of rapid tumor remissions have been observed in animal models and clinical trials,tumor relapses occur with multiple therapeutic resistance ***,while the mechanisms underlying the long-term therapeutic resistance are well-known,short-term adaptation remains less ***,more views shed light on short-term adaptation and hold that it provides an opportunity window for long-term *** this study,we explore a previously unreported mechanism in which tumor cells employ trogocytosis to acquire CAR molecules from CAR-T cells,a reversal of previously documented *** mechanism results in the depletion of CAR molecules and subsequent CAR-T cell dysfunction,also leading to short-term antigen loss and antigen *** type of intercellular communication is independent of CAR downstream signaling,CAR-T cell condition,target antigen,and tumor cell ***,it is mainly dependent on antigen density and CAR sensitivity,and is associated with tumor cell cholesterol *** mitigation of this trogocytosis-induced CAR molecule transfer can be achieved by adaptively administering CAR-T cells with antigen density-individualized CAR ***,our study reveals a dynamic process of CAR molecule transfer and refining the framework of clinical CAR-T therapy for solid tumors.

关键词： Together instance depletion

Active Magnetic Compensation Based on Parametric Resonance Magnetometer

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Journal of Shanghai Jiaotong university(science) 2024年第2期29卷 280-289页

作者：郭阳李绍良黄艺明骆曼箬刘华 School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Institute of Spacefight Control Technology Shanghai Key Laboratory of Space Intelligent Control TechnologyShanghai Engineer Research Center of InertiaShanghai 201109China

Based on the parametric resonance magnetometer(PRM)theory,this paper establishes an experimen-tal system of *** experimental results are consistent with the theoretical predictions.A PRM has been developed with sensitivity of 0.5 pT/Hz^(1/2),which can detect the magnitude of residual magnetic field;furthermore,a proportion-integration-differentiation(PID)closed-loop magnetic compensation system of the residual magnetic field also has been *** with open-loop compensation,the PID closed-loop compensation reduces the average value of the residual magnetic field in the z-axis direction from 0.0244nT to-0.0023nT,and the mean-square error from 0.2083 nT to 0.0691 *** the same way,the average value of the residual magnetic field in the y-axis direction is reduced from 0.0816nT to-0.0042nT,and the mean-square error from 0.1316nT to 0.0461 *** magnitude of residual magnetic fields in both directions is decreased to the order of picotesla(pT).In addition,based on the signal waveforms of the magnetometer,a method of verifying the effect of magnetic compensation is proposed.

关键词： magnetometer parametric resonance nuclear magnetic resonance gyroscope magnetic compensa-tion proportion-integration-differentiation(PID)

Engineering Quantum Criticality for Quantum Dot Power Harvesting

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Chinese Physics Letters 2024年第2期41卷 14-25页

作者：王金义年磊磊吕京涛 School of Physics and Astronomy Yunnan UniversityKunming 650091China School of Physics Institute for Quantum Science and Engineeringand Wuhan National High Magnetic Field CenterHuazhong University of Science and TechnologyWuhan 430074China

Coupling of quantum-dot circuits to microwave photons enables us to investigate photon-assisted quantum ***,we revisit this typical circuit quantum electrodynamical setup by introducing the Kerr nonlinearity of *** exploiting quantum critical behavior,we propose a powerful scheme to control the power-harvesting efficiency in the microwave regime,where the driven-dissipative optical system acts as an energy *** drives electron transport against a load in the quantum-dot *** energy transfer and,consequently,the harvesting efficiency are enhanced near the critical *** the critical point moves towards to low input power,high efficiency within experimental parameters is *** results complement fundamental studies of photon-to-electron conversion at the nanoscale and provide practical guidance for designs of integrated photoelectric devices through quantum criticality.

关键词： quantum critical microwave

Physical activity and amyloid beta in middle-aged and older adults:A systematic review and meta-analysis

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Journal of Sport and Health science 2024年第2期13卷 133-144页

作者： María Rodriguez-Ayllon Patricio Solis-Urra Cristina Arroyo-ávila Miriam álvarez-Ortega Pablo Molina-García Cristina Molina-Hidalgo Manuel Gómez-Río Belinda Brown Kirk I.Erickson Irene Esteban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and Social sciences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Physical Medicine and Rehabilitation Service Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Psychology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia School of Medical and Health sciences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health research Institute Neuroscience Institute OrlandoOrlandoFL 32803USA Physiopathology of Obesity and Nutrition research center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels *** aimed to explore the relationship between physical activity and Aβin middle-aged and older ***:A systematic search of PubMed,Web of science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,*** were eligible if they included physical activity and Aβdata in adults aged 45 years or ***-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβ***:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and *** physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older ***,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included *** observational studies,higher levels of physical activity were positively associated with Aβonly in ***,further research is needed t

关键词： Aging Cognitive impairment Dementia Exercise PET

High genetic diversity and strong differentiation in dramatically fluctuating populations of Zostera japonica(Zosteraceae):implication for conservation

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Journal of plant Ecology 2018年第5期11卷 789-797页

作者： Kai Jiang Po-Keung Eric Tsang Na-Na Xu Xiao-Yong Chen School of Ecological and Environmental sciences Shanghai Key Lab of Urban Ecological Processes and Eco-RestorationEast China Normal UniversityShanghai 200241China Shanghai chenshan plant science research center Chinese Academy of SciencesChenshan Botanical GardenShanghai 201602China Department of science and Environmental Studies The Education University of Hong KongHong KongChina School of Fishery Zhejiang Ocean UniversityZhoushan 326022China

Aims Seagrasses provide a variety of ecosystem goods and services,but they are subjected to frequently anthropogenic *** this study,we genotyped samples collected from Zostera japonica mead-ows with dramatic fluctuations in the area in order to understand the distribution of genetic variation within and among *** We collected samples from eight extant populations along coastal areas of southern *** polymorphic microsatellites were adopted to genotype the *** of genetic diversity and differentiation were calculated with general *** Findings High levels of genetic diversity were found in the studied populations,suggesting that the effective population size has not decreased signifi-cantly,which was supported by no signs of recent *** genetic diversity reflects an important role of sexual seedling recruit-ment in *** *** found a significant relationship between genetic differentiation and the shortest sea surface distance of populations,suggesting that ocean currents play a critical role in shap-ing the genetic structure of *** *** soft-ware analysis clustered the eight populations into two groups:western and eastern populations separated by the Qiongzhou Strait/Leizhou Peninsula,hinting that there was very limited gene flow through the narrow strait in this marine *** populations had high contribu-tion diversity and,thus,high priority for in situ conservation.

关键词： Seagrass Zostera japonica Genetic diversity Genetic differentiation Microsatellites

The Minimum Centroid Branch Spanning Tree Problem

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Journal of the Operations research Society of China 2024年第2期12卷 528-539页

作者： Hao Lin Cheng He School of science Henan University of TechnologyZhengzhou450001HenanChina

For a spanning tree T of graph G,the centroid of T is a vertex v for which the largest component of T-v has as few vertices as *** number of vertices of this component is called the centroid branch weight of *** minimum centroid branch spanning tree problem is to find a spanning tree T of G such that the centroid branch weight is *** application to design of communication networks,the loads of all branches leading from the switch center should be as balanced as *** this paper,we prove that the problem is strongly NP-hard even for bipartite ***,the problem is shown to be polynomially solvable for split graphs,and exact formulae for special graph familis,say Kn_(1),n_(2),...,n_(k)and P_(m)×P_(n),are presented.

关键词： Spanning tree optimization Centroid branch-NP-hardness Polynomial-time algorithm