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Analysis of Chinese Anti-Suit Injunctions in SEP Litigation

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科技与法律（中英文） 2025年第1期 138-148页

作者： Ou Fuyong Zhang Xiaoxiao Law School Hunan Normal UniversityChangsha 410081China

In this article,two cases of Standard Essential Patents,ruled by the Supreme People's Court of the People's Republic of China,are presented and *** first Chinese anti-suit injunction in SEP litigation appeared in the first case through the method of behavior preservation,and the second case illustrates a clear intent by the Chinese courts to compete for global royalty rate *** international concerns raised about these cases,it is proved that the anti-suit injunction cases in China do not show any abusive or illegal *** worldwide anti-suit injunctions in China are granted legitimately with legal jurisdiction over the cases,sufficient legal grounds for behavior preservation with the nature of anti-suit injunctions,the necessity of granting worldwide injunctions,and suitable granting *** pieces of advice are proposed for the future application of anti-suit injunctions,including improvements in the predictability of validity scope,consistency of implementation,and clarification of penalties.

关键词： anti-suit injunction anti-anti-suit injunction FRAND royalty rate jurisdiction SEP

Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2982-2997页

作者： Hongli Li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina National Clinical Research Center for Metabolic Diseases ChangshaHunan ProvinceChina Hunan Academy of Chinese Medicine ChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina

Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut *** aim of this study was to investigate systemic changes that occur in Alzheimer’s disease,in particular the association between changes in peripheral organ metabolism,changes in gut microbial composition,and Alzheimer’s disease *** do this,we analyzed peripheral organ metabolism and the gut microbiota in amyloid precursor protein-presenilin 1(APP/PS1)transgenic and control mice at 3,6,9,and 12 months of ***-month-old APP/PS1 mice exhibited cognitive impairment,Alzheimer’s disease-related brain changes,distinctive metabolic disturbances in peripheral organs and fecal samples(as detected by untargeted metabolomics sequencing),and substantial changes in gut microbial composition compared with younger APP/PS1 ***,a strong correlation emerged between the gut microbiota and kidney metabolism in APP/PS1 *** findings suggest that alterations in peripheral organ metabolism and the gut microbiota are closely related to Alzheimer’s disease development,indicating potential new directions for therapeutic strategies.

关键词： Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis

UNIFORM SUPERAPPROXIMATION OF THE DERIVATIVE OF TETRAHEDRAL QUADRATIC FINITE ELEMENT APPROXIMATION

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Journal of Computational Mathematics 2005年第1期23卷 75-82页

作者： Jing-hongLiu Qi-dingZhu InstituteofAppliedMathematics HunanUniversityChangsha~10082China)(SchoolofMathematicsandComputerScienceHunanNormalUniversityChangsha410081China SchoolofMathematicsandComputerScience HunanNormalUniversityChangsha410081China

In this paper,we will prove the derivative of tetrahedral quadratic finite element ap-proximation is superapproximate to the derivative of the quadratic Lagrange interpolant of the exact solution in the L^∞-norm, which can be used to enhance the accuracy of the derivative of tetrahedral quadratic finite element approximation to the derivative of the exact solution。

关键词： tetrahedron superapproximation finite element

Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin Jin Yiming Qin Feifei Yuan Hongbin Lu Jianzhong Hu Yong Cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2

Quantum Inequality for Negative Energy Density States of Massive Dirac Field in Four-Dimensional Spacetime

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Chinese Physics Letters 2003年第12期20卷 2105-2106页

作者：舒维星吴普训余洪伟 DepartmentofPhysicsandInstituteofPhysics HunanNormalUniversityChangsha410081

Negative energy density and the quantum inequality are examined for the Dirac field. A proof is given of the quantum inequality for negative energy densities in the massive Dirac field produced by the superposition of... 详细信息

关键词： Quantum Inequality Negative Energy Density States Massive Dirac Field Four-Dimensional Spacetime

Entropy of the Schwarzschild Black Hole in the Painlevé and the Lemaitre Coordinates

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Chinese Physics Letters 2004年第3期21卷 432-434页

作者：荆继良陈松柏 InstituteofPhysicsandDepartmentofPhysics HunanNormalUniversityChangsha410081

In the Painleve and the Lemaitre coordinates, the statistical-mechanical entropies of the Schwarzschild black hole arising from the quantum scalar field are investigated by using the "t Hooft"s brick wall model. At first sight, it seems that the results would be different from that in the standard Schwarzschild coordinate since both the Painleve and the Lemaitre spacetimes do not possess the event horizon obviously. However, we prove that the entropies in these coordinates are exactly equivalent to that in the Schwarzschild coordinate.

关键词： Gravitation and cosmology Astrophysics and astroparticles

Higher-Dimensional Cosmological Models with Density-Parameter-Dependent Cosmological Constant

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Chinese Physics Letters 2004年第8期21卷 1670-1672页

作者：黄秀菊王永久 InstituteofPhysics HunanNormalUniversityChangsha410081

We discuss the evolution of the scale factor in a higher-dimensional cosmological model in which the cosmological constant is given by the scalar arisen by the contraction of the stress-energy tensor.

关键词： Gravitation and cosmology Astrophysics and astroparticles

Stability of Bright Solitons in Bose-Einstein Condensates

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Chinese Physics Letters 2004年第10期21卷 1881-1883页

作者：俞慧友颜家壬谢琼涛 DepartmentofPhysics HunanNormalUniversityChangsha410081

We investigate the stability of bright solitons in Bose-Einstein condensates by including a feeding term and a loss one in the Gross-Pitaevskii equation. Based on the direct approach of perturbation theory for the nonlinear Schrodinger equation, we give the explicit dependence of the height and other related quantities of bright solitons on the feeding and loss term. It is found that the three-body recombination loss plays a crucial role in stabilizing bright solitons.

关键词： Quantum gases liquids and solids Quantum information and quantum mechanics

Asymptotic Tails of Massive Scalar Fields in a Stationary Axisymmetric EMDA Black Hole Geometry

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Chinese Physics Letters 2004年第10期21卷 1873-1876页

作者：潘启沅荆继良 InstituteofPhysics HunanNormalUniversityChangsha410081

The late-time tail behaviour of massive scalar fields is studied analytically in a stationary axisymmetric Einstein-Maxwell Dilaton-Axion (EMDA) black hole geometry. It is shown that the asymptotic behaviour of massive perturbations is dominated by the oscillatory inverse power-law decaying tail t(-(l+3/2)) sin(mut) at the intermediate late times, and by the asymptotic tail t(-5/6) sin(mut) at asymptotically late times, with mu being held mass. Our result seems to suggest that the intermediate tails t(-(l+3/2)) sin(mut) and the asymptotically tails t(-5/6) sin(mut) may be a quite general feature for evolution of massive scalar fields in any four-dimensional asymptotically flat rotating black hole backgrounds.

关键词： Gravitation and cosmology Astrophysics and astroparticles