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Assessment of periportal fibrosis in Schistosomiasis mansoni patients by proton nuclear magnetic resonance-based metabonomics models

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World Journal of Hepatology 2022年第4期14卷 719-728页

作者： Milena Lima Rodrigues Tatiane Priscila Santos Rodrigues da Luz Caroline Louise Diniz Pereira Andrea Dória Batista Ana Lúcia Coutinho Domingues Ricardo Oliveira Silva Edmundo Pessoa Lopes Programa de Pós-Graduação em Medicina Tropical Centro de Ciências MédicasUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil Programa de Pós-Graduação em Química Centro de Ciências Exatas e da NaturezaUniversidade Federal de PernambucoRecife 50670-740PernambucoBrazil Hospital das Clínicas Departamento de Medicina ClínicaUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil

BACKGROUND The evaluation of periportal fibrosis(PPF)is essential for a prognostic assessment of patients with Schistosomiasis *** WHO Niamey Protocol defines patterns of fibrosis from abdominal ultrasonography,^(1)H-nuclear magnetic resonance(NMR)-based metabonomics has been employed to assess liver fibrosis in some *** To build 1H-NMR-based metabonomics models(MM)to discriminate mild from significant periportal PPF and identify differences in the metabolite *** A prospective cross-sectional study was performed on schistosomiasis patients at a University Hospital in Northeastern *** evaluated 41 serum samples from 10 patients with mild PPF(C Niamey pattern)and 31 patients with significant PPF(D/E/F Niamey patterns).MM were built using partial least squares-discriminant analysis(PLS-da)and orthogonal projections to latent structures discriminant analysis(OPLS-da)*** PLS-da and OPLS-da resulted in discrimination between mild and significant PPF groups with R2 and Q2 values of 0.80 and 0.38 and 0.72 and 0.42 for each model,*** OPLS-da model presented accuracy,sensitivity,and specificity values of 92.7%,90.3%,and 100%to discriminate significant *** metabolites identified as responsible by discrimination were:Nacetylglucosamines,alanine,glycolaldehyde,carbohydrates,and *** MMs discriminated mild from significant PPF patterns in patients with Schistosomiasis mansoni through identification of differences in serum metabolites profiles.

关键词： Metabolomics Portal hypertension Schistosoma mansoni Biomarkers Neglected disease Nuclear magnetic resonance

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Structure and genetic diversity of natural populations of Guadua weberbaueri in the southwestern Amazon,Brazil

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Journal of Forestry Research 2021年第2期32卷 755-763页

作者： Glória da Silva Almeida Leal Fabrício Assis Leal Hugo Teixeira Gomes Anderson Marcos de Souza Sabina Cerruto Ribeiro Jonny Everson Scherwinski-Pereira centro Multidisciplinar Universidade Federal do AcreCruzeiro do SulAcreBrazil Universidade de Brasília BrasíliaDistrito FederalBrazil centro de ciências Biológicas e da natureza Universidade Federal do AcreRio BrancoAcreBrazil centro de Pesquisa e Aplicação de Bambu e Fibras Naturais Universidade de Brasília–CPAB/UnBBrasíliaDistrito FederalBrazil Embrapa Recursos Genéticos e Biotecnologia Av.W5 Norte(final)PqEBBrasíliaDistrito Federal 70770-917Brazil

The Brazilian state of Acre has an extensive natural reserve of bamboo,making it one of the largest in loco gene *** aim of this study was to characterize the structure and genetic diversity of Guadua weberbaueri *** two populations,one native(FAPB)and the other anthropized(FAPBA),using ISSR *** results show that the FAPB population exhibited higher values for all estimates of population ***,the FAPBA population also showed high heterozygosity,corroborated by estimated gene flow(Nm=3.9)between the *** study of the association between Nei’s genetic distances and the geographic distances between the populations were significantly correlated(r=0.45,p=0.01),corroborated by the dendrogram revealing two distinct groups corresponding to the collection sites,without mixing classes between populations in the same *** for the coancestry coefficient,pairs of individuals in the first distance class were positive and significant,indicating that plants that are geographically closer share common alleles with a frequency greater than by chance,which means that there is a tendency that geographically closer individuals are *** presented similar genetic structure when the geographical distance between them was up to 56 m for FAPB and up to 156 m for *** was concluded that anthropized environments exhibit less genetic diversity than native environments,inferring risks for species conservation if appropriate and planned management techniques are not adopted.

关键词： Guadua Bamboo Genetic diversity Amazon rainforest Anthropized and native populations Underutilization plants

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Effects of environmental conditions and space on species turnover for three plant functional groups in Brazilian savannas

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Journal of Plant Ecology 2019年第6期12卷 1047-1058页

作者： Hélio Menegat Divino Vicente Silvério Henrique A.Mews Guarino R.Colli Ana Clara Abadia Leonardo Maracahipes-Santos Lorrayne A.Gonçalves Jhany Martins Eddie Lenza Universidade do Estado de Mato Grosso Campus Universitário de Nova XavantinaRua Prof.Dr.Renato Figueiro VarellaCaixa Postal0878690-000Nova XavantinaMTBrazil Instituto de Pesquisa Ambiental da Amazônia Rua Horizontina 10478640-000CanaranaMTBrazil centro de ciências Biológicas e da natureza Universidade Federal do AcreCaixa Postal 50069920-900Rio BrancoACBrazil departamento de Zoologia Universidade de Brasília70910-900BrasíliaDFBrazil

Aims Different plant functional groups display diverging responses to the same environmental ***,we assess the effects of environmental and spatial predictors on species turnover of three functional groups of Brazilian savannas(Cerrado)plants—trees,palms and lianas—across the transition zone between the Cerrado and Amazon biomes in central *** We used edaphic,climatic and plant composition data from nine one-hectare plots to assess the effects of the environment and space on species turnover using a Redundancy Analysis and Generalized Dissimilarity Modeling(GDM),associated with variance *** Findings We recorded 167 tree species,5 palms and 4 liana *** variation was most important in explaining species turnover,relative to geographic distance,but the best predictors differed between functional groups:geographic distance and silt for lianas;silt for palms;geographic distance,temperature and elevation for *** distances alone exerted little influence over species turnover for the three functional *** pure environmental variation explained most of the liana and palm turnover,while tree turnover was largely explained by the shared spatial and environmental *** effects of geographic distance upon species turnover leveled off at about 300 km for trees,and 200 km for lianas,whereas they were unimportant for palm species *** results indicate that environmental factors that determine floristic composition and species turnover differ substantially between plant functional groups in ***,we recommend that studies that aim to investigate the role of environmental conditions in determining plant species turnover should examine plant functional groups separately.

关键词： environmental gradient spatial gradient Neotropical savannas ecological tension zone life forms ecological groups

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The Effect of the Atmospheric and Cloud Properties on the Retrieval of Fog Microphysics at Night for MSG/SEVIRI: A Sensitivity Test Using LibRadtran

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Atmospheric and Climate Sciences 2021年第3期11卷 441-457页

作者： Aliton Oliveira da Silva Augusto Jose Pereira Filho Hugo Abi Karam departamento de ciências Atmosféricas Instituto de Astronomia Geofísica e Ciências Atmosféricas Universidade de S&#227 o Paulo S&#227 o Paulo Rua do Mat&#227 o 1226 S&#227 o Paulo Brazil centro de ciências Matemáticas e da natureza Instituto de Geociências Federal Universidade Federal do Rio de Janeiro Rio de Janeiro Rua Athos da Silveira Ramos 274 Rio de Janeiro Brazil

The simplest way of building a look-up table (LUT) for the retrieval of cloud microphysical properties is to use a standard atmospheric profile and vertically uniform cloud microphysics. Such an assumption has been demonstrated to be incoherent with in-cloud observations. This paper aims to show the effect of some atmospheric conditions associated with fog as well as its macro-and microstructure on brightness temperature (BT) for the MSG/ SEVIRI satellite using libRadtran. The sensitivity tests were performed by gradually changing some features from the initial data, such as cloud cover, total water vapor column, thermal inversion intensity, fog depth, fog microstructure, and others. The results revealed that some variables can cause significant variations on BT and, consequently, discrepancies in the retrieval of fog microphysical properties. Also, a variation as high as 0.5°C was found on BT just by switching uniform to the non-uniform profile of fog microphysics depending on the channel, the droplet size, and optical thickness.

关键词： Fog Microphysics MSG/SEVIRI Sensitivity Test LibRadtran

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Natural enemies depend on remnant habitat size in agricultural landscapes

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Journal of Forestry Research 2015年第2期26卷 469-477页

作者： Mainara Xavier Jordani erica Hasui Vinicius Xavier da Silva Laboratorio de Ecologia Animal Departamento de Zoologia e BotanicaUniversidade Estadual Paulista-UNESPRua Cristovao Colombo2265Jardim NazarethSao Jose Do Rio PretoSP CEP 15054-000Brazil Laboratorio de Ecologia de Fragmentos do Sul de Minas Gerais-ECOFRAG Instituto Ciencias da NaturezaUniversidade Federal de Alfenas-UNIFAL–MGRua Gabriel Monteiro da Silva700CentroAlfenasMG CEP 37130-000Brazil

In recent decades,the consequences of habitat fragmentation have been of growing concern,because it is particularly important to understand how fragmentation may affect biodiversity,an ecological *** tested two hypotheses：（1） that natural fragment size in agricultural landscapes indirectly affects the herbivore through effects on natural predator populations;and（2） predator activity into the crop reduces along the distance from the natural fragment *** 2008 and 2009,we conducted our study in seven forest remnants and in surrounding coffee plantations（fragments ranged from 6 to 105 ha,mean 49.28 ± 36.60 ha） in Southern Minas Gerais,*** were sampled by point counts,and insect predation was evaluated by using an artificial insect model（Koh and Menge 2006）.Our results suggest that although there were many potential predators（e.g.,wasps,ants,birds,and mammals）,birds were the most important taxon *** covariance analysis supported the hypothesis that patch size affected the number of larvae predation by overall taxi,but there was no support for a distance *** findings suggest that natural enemies’ ecological service（mainly from birds） declined with remnant reduction,which has implications not only for human welfare,but also in strengthening the economic justifications for conserving the remaining natural habitats and biodiversity in agricultural landscapes.

关键词： Ecosystem service Fragmentation Isolation Insectivore Predation

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Use of Agaricus bisporus mushroom in beef burgers:antioxidant,flavor enhancer and fat replacing potential

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食物生产加工与营养(英文) 2019年第1期1卷 64-78页

作者： Iliani Patinho Erick Saldaña Miriam Mabel Selani Adriano Costa de Camargo Thais Cardoso Merlo Beatriz Schmidt Menegali Anna Paula de Souza Silva Carmen J.Contreras-Castillo departamento de Agroindústria Alimentos e Nutrição(LAN)Escola Superior de Agricultura“Luiz de Queiroz”(ESALQ)Universidade de São Paulo(USP)Avenida Pádua Dias11PiracicabaSP 13418-900Brazil centro de ciências da natureza Campus Lagoa do SinoUniversidade Federal de São CarlosRod.Lauri Simões de BarrosKm 12BuriSPBrazil departamento de ciencias Vegetales Facultad de Agronomía e Ingeniería ForestalPontificia Universidad Católica de ChileCasilla306-22 SantiagoChile Facultad de Ingeniería Agroindustrial Universidad Nacional de Moquegua(UNAM)MoqueguaPeru

This study aimed to evaluate the potential use of Agaricus bisporus mushroom as a natural antioxidant,fat/salt substitute and flavor enhancer in beef *** treatments were considered using a fractional factorial design(salt[0.5,1.25 and 2.0%],fat[10,15 and 20%]and mushroom content[0,15 and 30%]).Treatments were characterized by instrumental and sensory *** statistical design indicated that fat content had little influence on the *** principal component analysis showed that the incorporation of mushrooms and salt modified the texture,moisture and water *** stability decreased as the salt content increased,at a low-fat ***,the sensory profile was affected by the mushroom and salt contents,with the fat content exerting the least ***,mushroom incorporation in beef burger may be a feasible strategy to reduce the fat content of beef burgers.

关键词： Beef burger Agaricus bisporus Lipid oxidation Texture profile analysis descriptive analysis

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Severity of Leaf Rust and Brown Eyespot in Genotypes of Coffea arabica *** with High Plant density

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American Journal of Plant Sciences 2014年第25期5卷 3702-3709页

作者： Wagner Nunes Rodrigues Marcelo Antonio Tomaz Marcio Antonio Apostolico Tafarel Victor Colodetti Lima deleon Martins Leonardo Fardim Christo Sebastiao Vinicius Batista Brinate Waldir cintra de Jesus Jr. Jose Francisco Teixeira do Amaral centro de ciencias Agrarias Universidade Federal do Espírito Santo(CCA/UFES)AlegreBrazil centro de ciencias da natureza Universidade Federal de Sao Carlos(UFSCAR)BuriBrazil

This study investigated the severity of leaf rust and brown eyespot in genotypes of Coffea arabica L. cultivated with high plant density in the region of Caparaó-ES. The experiment was conducted in a competition field, cultivated with high plant density (8333 plants per hectare), following a randomized block design, with 16 genotypes and four replications. The plants were evaluated during consecutive harvests to study two complete reproductive cycles (from 2010 to 2012). data were obtained for the phenologicalstages of flowering, graining, maturation and vegetative rest of each cycle. The severity of leaf rust (Hemileia vastratrix) and brown eyespot (Cercospora coffeicola) was evaluated using descriptive scales. It was observed that the genotypes are able to keep a considerable level of resistance to the leaf rust and brown eyespot when cultivated with increased density. The genotypes presented variability regarding the severity of the leaf rust and brown eyespot, indicating the existence of differential levels of resistance between them. For cultivation with high plant density, the genotypes Katipó, Paraíso MG H419-1, H419-3-3-7-16-4-1-1, Araponga MG1, Catucaí Amarelo 24/137, Catiguá MG2, Sacramento MG1, Pau-Brasil MG1, Catiguá MG3, Oeiras MG 6851 and Tupi present higher level of resistance for leaf rust. In addition, the genotypes Paraíso MG H419-1, Catiguá MG2, Pau-Brasil MG1, Catiguá MG3, Oeiras MG 6851, Tupi, Catuaí IAC 44, Catuaí IAC 81 and Catuaí IAC 144 present higher level of resistance for brown eyespot.

关键词： Arabica Coffee Hemileia vastratrix Cercospora coffeicola Genetic Control Resistance

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Visualizing Fit between dengue and Climatic Variables on Capitals of the Brazilian Northeast Region by Generalized Additive Models

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Open Journal of Epidemiology 2018年第4期8卷 259-275页

作者： Julio Cesar Barreto da Silva Hugo Abi Karam Carlos José Saldanha Machado Programa de Pós-graduaç o em Meio Ambiente (PPGMA) Universidade do Estado do Rio de Janeiro (UERJ) Rio de Janeiro Brasil departamento de Meteorologia do Instituto de Geociências (IGEO) Centro de Ciências Matemáticas e da Natureza (CCMN) Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brasil Instituto de Comunicaç o e Informaç o científica e Tecnológica em Saúde Laboratório de Informaç o científica e Tecnológica em Saúde Funda&#231 o Oswaldo Cruz (FIOCRUZ) Ministério da Saúde Rio de Janeiro Brasil

Recent analysis indicates that the numbers of dengue cases may be as high as 400 million/year in the world. According to the Ministry of Brazilian Health, in 2015, there were 1,621,797 probable cases of dengue in the country including all classifications except discarded, the highest number recorded in the historical series since 1990. Many studies have found associations between climatic conditions and dengue transmission, especially using generalized models. In this study, Generalized Additive Models (GAM) was used associated to visreg package to understand the effect of climatic variables on capitals of Northeast Brazilian, from 2001 to 2012. From 12 climatic variables, it was verified that the relative humidity was the one that obtained the highest correlation to dengue. Afterwards, GAM associated with visreg was applied to understand the effects between them. Relative humidity explains the dengue incidence at an adjusted rate of 78.0% (in São Luis-MA) and 82.3% (in Teresina-PI) delayed in, respectively, -1 and -2 months.

关键词： Aedes aegypti dengue GAM Visreg Package

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BiFeO_(3) codoping with Ba,La and Ti:Magnetic and structural studies

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Journal of Advanced Dielectrics 2015年第4期5卷 53-60页

作者： O.García-Zaldívar S.Díaz-Castañón F.J.Espinoza-Beltran M.A.Hernández-Landaverde G.López J.Faloh-Gandarilla F.Calderón-Piñar Facultad de Física-Instituto de ciencia y Tecnología de Materiales Universidad de La Habana San Láazaro y L VedadoLa Habana 10400Cuba ciNVESTAV-Unidad Querétaro Libramiento Norponiente No.2000 Real de JuriquillaQuerétaroQro.76230México Instituto Latino-Americanode ciênciasda Vidaeda natureza Universidade Federalda Integração Latino-Americana (ILCVN-UNILA)Avenida Tancredo NevesPTIBloco 6 CEP:85866-000-Foz do Iguaçu-ParanaBrazil División Materiales Avanzados Instituto Potosinode Investigación científica Tecnológica San Luis Potosí CP78216Méexico

Conventional solid state reaction method,from oxides and carbonates,was employed to prepare bismuth(Bi)-based multiferroic *** undoped BiFeO_(3)(BFO)and the codoped system with Ba,La and Ti(Bi_(1-x)Ba_(x)Fe_(1-y)Ti_(y)O_(3),Bi_(1-x-z)Ba_(x)LazFe_(1-y)TiyO_(3))with x,y,z=0.1 were prepared stoichiometrically and sintered at two different *** structural and magnetic properties were investigated at room *** measurements confirm the obtaining of the rhombohedral perovskite structure of the BFO family *** the undoped system,some reflections of undesired phases are present for two different sintering temperatures,while for the doped system only one phase is present for both *** magnetic characterization at room temperature revealed remarkable differences between the ceramic *** results show that for undoped BFO system,spontaneous magnetization is not observed at room ***,in doped one,a well-defined ferromagnetic behavior is observed at room temperature,possible,due to the suppression of the spatially modulated spin structure of BFO promoted by the reduction of the rhombohedral distortion and the weakening of the Bi-O *** XPS results confirm the presence of oxygen vacancies and the coexistence of Fe^(3+)and Fe^(2+) in all the studied *** measurements reveal that the dopant incorporation has not a direct effect in Neel temperature but possibly yes in ferroelectric-paraelectric transition.

关键词： Multiferroics XPS magnetic bismuth ferrite BiFeO_(3)

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Cost Benefit Analysis to Select Clean Energy Solutions in dairy Farm Milk Collection Posts in Azores

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Journal of Energy and Power Engineering 2011年第4期5卷 308-316页

作者： A. Rodrigues T. dentinhol, C. Silva E. Azevedo Gabinete de Gestao e Conservaqao da natureza Departamento das Ciencias Agrarias University of Azores Largo da Igreja 9700-181 Terra-Che Terceira-Aqores Instituto Superior Tecnico Technical University of Lisbon MIT-Portugal Sustainable Energy Systems Av. Rovisco Pais 1. 1049-001 Lisboa centro de Estudos do Clima Meteorologia e Mudancas Globais University of Azores Largo da Igreja 9700-181 Terra-Ch6 Terceira-Agores

The purpose of this paper is to evaluate the possibility of implementation of alternative renewable energy micro-generation installations in dairy farm milk collection posts, from the technical, economical and environmental perspectives. Work was performed through dairy farm milk collection post energy audits. Weather data was obtained from CLIMAAT and MacSIMAR projects and introduced in a renewable energy solutions calculator (HOMER). Moreover, a system design from the available portfolio of micro-generation devices was defined and a cost benefit analysis of the selected alternatives was performed. From the analyzed solutions, the set of PV (20 kW) and Wind (3 kW) with no batteries revealed to be the best one. The sensitivity analysis indicated that wind micro-turbines should be installed except if the solar radiation is maximum and that in no case the use of batteries is an advantage. For systems requiring a certain degree of energy (in this case with an average of 350 kW/day), the implementation of micro generation systems, like the ones evaluated, will never be economically feasible in terms of Total Economic Value, even with generous feed-in tariff schemes. It is preferable that grid operators make investments in renewable energy production.

关键词：成本效益分析奶牛场亚速尔群岛清洁能源牛奶可再生能源收藏经济价值

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