检索结果-南通市图书馆

Spinal cord injury-induced cognitive impairment: a narrative review

Neural Regeneration Research 2022年第12期17卷 2649-2654页

作者： Oscar V.Alcántar-Garibay Diego Incontri-Abraham Antonio Ibarra centro de Investigación en Ciencias de la Salud(CICSA) Facultad de Ciencias de la SaludUniversidad Anáhuac México Campus NorteHuixquilucanEstado de MéxicoMéxico

Spinal cord injury is a serious damage to the spinal cord that can lead to life-long *** on its etiology,spinal cord injury can be classified as traumatic or non-traumatic spinal cord ***,the pathology of spinal cord injury can be divided into two phases,a primary injury phase,and a secondary injury *** primary spinal cord injury phase involves the initial mechanical injury in which the physical force of impact is directly imparted to the spinal cord,disrupting blood vessels,axons,and neural cell *** the primary injury,a cascade of secondary events begins,expanding the zone of neural tissue damage,and exacerbating neurological *** injury is a progressive condition characterized by pro-inflammatory cytokines,reactive oxygen species,oxidative damage,excitatory amino acids such as glutamate,loss of ionic homeostasis,mitochondrial dysfunction,and cell *** secondary phase lasts for several weeks or months and can be further subdivided into acute,subacute,and *** of the most frequent and devastating complications developed among the spinal cord injury population is cognitive *** risk of cognitive decline after spinal cord injury has been reported to be 13 times higher than in healthy *** exact etiology of this neurological complication remains unclear,however,many factors have been proposed as potential contributors to the development of this disorder,such as concomitant traumatic brain injury,hypoxia,anoxia,autonomic dysfunction,sleep disorders such as obstructive sleep apnea,body temperature dysregulation,alcohol abuse,and certain *** review focuses on a deep understanding of the pathophysiology of spinal cord injury and its relationship to cognitive *** highlight the main mechanisms that lead to the development of this neurological complication in patients with spinal cord injury.

关键词： autonomic dysfunction cognitive impairment spinal cord injury traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Usefulness of the CONUT index upon hospital admission as a potential prognostic indicator of COVID-19 health outcomes

引用

Chinese Medical Journal 2022年第2期135卷 187-193页

作者： Adrian K.Bengelloun Guillermo J.Ortega Julio Ancochea Ancor Sanz-Garcia Diego A.Rodriguez-Serrano Guillermo Fernandez-Jimenez Rosa Giron Elena Avalos Joan B.Soriano J.Ignacio de Ulibarri Facultad de Medicina Universidad Autónoma de MadridMadridSpain Unidad de Análisis de Datos Instituto de Investigación Sanitaria del Hospital de la PrincesaMadridSpain Servicios de Neumología Admisión y Documentación ClínicaCuidados Intensivos y Nutrición y DietéticaHospital Universitario de La PrincesaMadridSpain centro de Investigación en Red de Enfermedades Respiratorias(CIBERES) Instituto de Salud Carlos III(ISCIII)MadridEspañaSpain

Background:In-hospital mortality in patients with coronavirus disease 2019(COVID-19)is *** prognostic indices are needed to identify patients at high-risk of COVID-19 health *** aimed to determine the usefulness of the CONtrolling NUTritional status(CONUT)index as a potential prognostic indicator of mortality in COVID-19 patients upon hospital ***:Our study design is of a retrospective observational study in a large cohort of COVID-19 *** addition to descriptive statistics,a Kaplan-Meier mortality analysis and a Cox regression were performed,as well as receiver operating curve(ROC).Results:From February 5,2020 to January 21,2021,there was a total of 2969 admissions for COVID-19 at our hospital,corresponding to 2844 ***,baseline(within 4 days of admission)CONUT index could be scored for 1627(57.2%)***’age was 67.3±16.5 years and 44.9%were *** CONUT severity distribution was:194(11.9%)normal(0-1);769(47.2%)light(2-4);585(35.9%)moderate(5-8);and 79(4.9%)severe(9-12).Mortality of 30 days after admission was 3.1%in patients with normal risk CONUT,9.0%light,22.7%moderate,and 40.5%in those with severe CONUT(Pdeath associated with a greater baseline CONUT stage was sustained in a multivariable Cox regression model(Plation,and other clinical outcomes(all Pder the curve(AUC)and 95%confidence interval of 0.711(0.676-0746).Conclusion:The CONUT index upon admission is potentially a reliable and independent prognostic indicator of mortality and length of hospitalization in COVID-19 patients.

关键词： Admission Clinical risk CONUT COVID-19 Prognosis Score

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study

引用

Journal of Geriatric Cardiology 2022年第5期19卷 354-366页

作者： Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado Cardiology department Hospital Universitario Marqués de ValdecillaIDIVALSantanderSpain Cardiology department Hospital Universitario San JuanAlicanteSpain Cardiology department Complejo Hospitalario Universitario de AlbaceteAlbaceteSpain Cardiology department Hospital Universitario Puerta del MarCadizSpain Cardiology department Hospital Clínico Universitario Virgen de la ArrixacaMurciaSpain Cardiology department Hospital Clinico Universitario de SantiagoCIBERCVSantiago de CompostelaSpain Cardiology department Hospital Universitario de CrucesBilbaoSpain Cardiology department Hospital Regional Universitario de MálagaMalagaSpain Cardiology department Hospital Universitario Puerta de HierroMadridSpain Cardiology department Hospital Alvaro CunqueiroVigoSpain Cardiology department Hospital Juan Ramon JimenezHuelvaSpain Cardiology department Hospital Universitario de BadajozBadajozSpain Cardiology department Hospital Universitario Lucus AugustiLugoSpain Cardiology department Hospital de Torrevieja/VinalopóRibera SaludTorreviejaSpain Cardiology department Hospital Santa CruzLisboaPortugal Cardiology department Hospital Clínico Universitario Lozano BlesaZaragozaSpain Cardiology department Hospital Universitario Miguel ServetZaragozaSpain Cardiology department Hospital Germans Trias i PujolBadalonaSpain Cardiology department Hospital de MeridaMeridaSpain Cardiology department Hospital São BernardoSetúbalPortugal Cardiology department Hospital Clinico Universitario de ValenciaUniversidad de ValenciaCIBERCVValenciaSpain Cardiology department Hospital do Espirito SantoEvoraPortugal Cardiology department Centro Hospitalar de Vilanova de GaiaVilanova de GaiaPortugal Cardiology department Hospital de CabueñesGijonSpain Cardiology department Hospital Garcia de OrtaAlmadaPortugal Cardiology department Complejo Asistencial Universitario de LeónLeonSpain

OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT ***-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as *** Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex ***-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored *** stent thrombosis reported in the subgroup with 1-3 months DAPT *** compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes.

关键词： patients bleeding antithrombotic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Radioisotope production using lasers:From basic science to applications

引用

Matter and Radiation at Extremes 2024年第3期9卷 31-44页

作者： M.R.D.Rodrigues A.Bonasera M.Scisciò J.A.Pérez-Hernández M.Ehret F.Filippi P.L.Andreoli M.Huault H.larreur D.Singappuli D.Molloy D.Raffestin M.Alonzo G.G.Rapisarda D.lattuada G.L.Guardo C.Verona Fe.Consoli G.Petringa A.McNamee M.la Cognata S.Palmerini T.Carriere M.Cipriani G.Di Giorgio G.Cristofari R.de Angelis G.A.P.Cirrone D.Margarone L.Giuffrida D.Batani P.Nicolai K.Batani R.Lera L.Volpe D.Giulietti S.Agarwal M.Krupka S.Singh Fa.Consoli Cyclotron Institute Texas A&M UniversityCollege StationTexas 77840USA laboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare(LNS-INFN)CataniaItaly ENEA Fusion and Technologies for Nuclear Safety and Security Department-CFrascatiItaly centro de Láseres Pulsados(clpu) VillamayorSpain Universidad de Salamanca SalamancaSpain Centre lasers Intenses et Applications(CELIA) Universitéde BordeauxCNRSCEATalenceFrance HB11 Energy Holdings Pty FreshwaterNew South WalesAustralia School of Mathematics and Physics Queen’s University BelfastBelfastUnited Kingdom Dipartimento di Fisica e Astronomia“E.Majorana ”Università di CataniaCataniaItaly Facoltàdi Ingegneria e Architettura Universitàdegli Studi di Enna“Kore”EnnaItaly Dipartimento di Ingegneria Industriale Universitàdi Roma“Tor Vergata”RomaItaly Dipartimento di Fisica e Geologia Universitàdegli Studi di PerugiaPerugiaItaly Istituto Nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly ELI Beamlines Facility the Extreme Light Infrastructure ERICDolni BrezanyCzech Republic ETSIA Universidad Politécnica de MadridMadridSpain Dipartimento Fisica “E.Fermi”Universitàdi Pisa and INFNPisaItaly FZU–Institute of Physics of Czech Academy of Sciences PragueCzech Republic Institute of Plasma Physics of Czech Academy of Sciences PragueCzech Republic

The discovery of chirped pulse amplification has led to great improvements in laser technology,enabling energetic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few *** with energies of tens of MeV can be accelerated using,for instance,target normal sheath acceleration and focused on secondary *** such conditions,nuclear reactions can occur,with the production of radioisotopes suitable for medical *** use of high-repetition lasers to produce such isotopes is competitive with conventional methods mostly based on *** this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currently used in positron emission tomography and other *** the same time,we study the reactions^(10)B(p,α)^(7)Be and^(70)Zn(p,4n)^(67)Ga to put further constraints on the proton distributions at different angles,as well as the reaction^(11)B(p,α)^(8)Be relevant for energy *** experiment was performed at the 1 PW laser facility at VegaⅢin Salamanca,*** distributions of radioisotopes in the forward(with respect to the laser direction)and backward directions were measured using a high purity germanium *** results are in reasonable agreement with numerical estimates obtained following the approach of Kimura and Bonasera[*** ***.,Sect.A 637,164–170(2011)].

关键词： purity estimates backward

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aiming for the end of the COVID-19 pandemic:the what,how,who,where,and when

引用

Chinese Medical Journal 2023年第1期136卷 1-3页

作者： Joan B.Soriano Alberto Infante Servicio de Neumología Hospital Universitario de la PrincesaMadridSpain Facultad de Medicina Universidad Autónoma de MadridMadridSpain centro de Investigación en Red de Enfermedades Respiratorias(CIBERES) Instituto de Salud Carlos III(ISCIII)MadridSpain National School of Public Health Institute of Health Carlos IIIMadridSpain

Severe acute respiratory syndrome coronavirus 2(SARSCoV-2)is a new virus,still full of *** of September 2022,there have been over 605 million confirmed cases of coronavirus disease 2019(COVID-19),including 6.5 million deaths reported to the World Health Organization(WHO).[1]SARS-CoV-2 is a bad virus,which often produces new variants that scape natural immunity and sometimes vaccines[Figure 1].

关键词： immunity acute respiratory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Setting large-and medium-sized mammal restoration goals in a last mountain Chaco remnant from central Argentina

引用

Ecological Processes 2023年第2期12卷 86-97页

作者： Daniel Renison Harold Rusbelth Quispe-Melgar G.A.Erica Cuyckens Ana M.Cingolani centro de Ecología y Recursos Naturales Renovables Dr.Ricardo Luti Instituto de Investigaciones Biológicas y Tecnológicas Universidad Nacional de Córdoba–CONICET Ecosistemas argentinos Facultad de Ciencias de la Salud Universidad Continental centro de Estudios Territoriales Ambientales y Sociales(CETAS UNJu) Instituto de Ecorregiones Andinas(INECOA UNJu-CONICET) Instituto Multidisciplinario de Biología Vegetal CONICET-Universidad Nacional de Córdoba

Background Setting large-and medium-sized wild mammal（≥ 2 kg） restoration goals is important due to their role as ecosystem engineers and generalized numeric reductions. However, determining wild mammal restoration goals is very challenging due to difficulties in obtaining data on current mammal density and due to unclear information on what mammal density values should be used as a reference. Here we chose a 154 ha conservation area within one of the last remnants of the mountainous Chaco from central Argentina. We suspected that extensive and unreported defaunation had occurred due to past human pressure and the introduction of non-native mammals. To conduct the analyses, we used a simplified technique that integrates methods used in rangeland and ecological *** Eight native mammal species including only one herbivore species, and four non-native mammal species including three herbivore species were detected during 6113 camera trap days. We used known cattle densities as estimated by droppings and direct counts, together with the relative abundance indexes obtained from camera trap photos to calculate the densities of the other species, correcting for mammal size. densities for the least and most abundant native species were 0.2 and 1.33 individuals km-2, respectively; and for non-native species, 0.03 and 5.00 individuals km-2, respectively. Native and non-native species represented 0.8% and 99.2%, respectively, of the biomass estimates. Reference values for native herbivore biomass, as estimated from net primary productivity, were 68 times higher than values estimated for the study area(3179 vs. 46.5 kg km-2).Conclusions There is an urgent need to increase native mammals, with special emphasis on herbivore biomass and richness, while non-native mammal numbers must be reduced. As cattle are widespread in large portions of the globe and there is a lot of experience estimating their abundances, the ratio method we used extrapolating from cattle to other

关键词： Camera trap Mammal survey Reference biomass Exotic mammal

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

光学相干断层成像评估高血压性视网膜病变神经元损伤应用价值的研究

引用

中国全科医学 2024年第9期27卷 1082-1087页

作者：赵润泽孙小佳 Melba Marquez Hernandez 窦国睿空军军医大学西京医院眼科、全军眼科研究所陕西省西安市710032 Lázaro#701 esq.a Belascoaín Centro HabanaLa HabanaCuba.Hospital Clínico Quirúrgico“Hermanos Ameijeiras”(HHA)Calle San 10400Cube

背景当前高血压的患病率呈逐年增长趋势,其眼部并发症高血压视网膜病也日益受到关注。然而目前对于高血压性视网膜病变中神经元损伤的研究尚少。目的本研究以光学相干断层成像检查为检查手段,探究其在高血压性视网膜病变中神经元损伤评... 详细信息

背景当前高血压的患病率呈逐年增长趋势,其眼部并发症高血压视网膜病也日益受到关注。然而目前对于高血压性视网膜病变中神经元损伤的研究尚少。目的本研究以光学相干断层成像检查为检查手段,探究其在高血压性视网膜病变中神经元损伤评估中的应用和重要价值。方法纳入2019年3月—2020年7月于Hospital Clínico Quirúrgico“Hermanos Ameijeiras”(HHA医院)就诊的102例高血压患者为研究对象,同时纳入45名健康受试者,监测24 h动态血压,取24 h舒张压和收缩压的平均动脉血压值,测量眼压,计算眼灌注压。检测视盘区视网膜神经纤维(RNFL)厚度和黄斑区神经节细胞复合层(GCC)厚度。依据血压控制情况将患者分为血压控制组(n=51)和血压未控制组(n=51),45名健康受试者为对照组。采用Pearson相关性分析或Spearman秩相关分析探究血压、眼灌注压、视网膜病变与GCC厚度和血压、眼灌注压与视网膜病变的相关性,采用R 3.5.3软件进行中介作用分析。结果3组研究对象人种、收缩压、舒张压、平均动脉压、眼压、眼灌注压、视网膜病变比较,差异有统计学意义(P<0.05)。血压未控制组平均RNFL厚度低于对照组(P<0.05),血压控制组、血压未控制组GCC平均厚度低于对照组,血压未控制组GCC最小值低于对照组(P<0.05)。相关性分析结果显示,GCC平均厚度、上方GCC厚度、颞下方CCG厚度与收缩压、舒张压、眼灌注压、视网膜病变呈负相关(P<0.05),颞上方GCC厚度与收缩压、舒张压、眼灌注压呈负相关(P<0.05),下方GCC厚度与舒张压呈负相关(P<0.05),视网膜病变与收缩压、舒张压、眼灌注压呈正相关(P<0.05)。中介效应结果显示,“收缩压→GCC平均厚度→高血压性视网膜病变”效应显著,收缩压与GCC平均厚度呈正相关,GCC平均厚度与高血压性视网膜病变呈正相关(P<0.05)。收缩压对高血压性视网膜病变发生风险具有直接影响(β=0.013,95%CI=0.007~0.020,P<0.001),GCC平均厚度部分介导了收缩压对高血压性视网膜病变发生风险的影响(β=0.117,95%CI=0.014~0.360,P=0.04),中介效应占总效应的11.7%。结论光学相干断层成像检查是一种无创的眼科检查方法,可优于普通眼底检查提前发现高血压性视网膜神经元受损情况,对高血压导致视神经受损的不可逆盲和高血压靶器官受损进行早期预防和预警。

关键词：高血压性视网膜病变高血压光学相干断层成像术神经纤维中介分析

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Carbon pool dynamics after variable retention harvesting in Nothofagus pumilio forests of Tierra del Fuego

引用

Ecological Processes 2023年第1期12卷 66-84页

作者： Jimena E.Chaves Marie-Claire Aravena Acu?a Julián Rodríguez-Souilla Juan M.Cellini Nolan J.Rappa María V.Lencinas Pablo L.Peri Guillermo J.Martínez Pastur centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) laboratorio de Investigaciones en Maderas (LIMAD) Universidad Nacional de la Plata (UNLP) Nature Conservation & landscape Ecology University of Freiburg Instituto Nacional de Tecnología Agropecuaria (INTA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)

Background It is necessary to determine the implications for managing forest stands using variable retention harvesting for maintaining carbon and for calculating the effects of different harvesting practices on above-and belowground carbon balance in forest ecosystems. In this context, forest carbon management has gained more attention among managers and policy-makers during recent years. The aim of this study was to determine carbon pool dynamics in different forest ecosystem components after variable retention harvesting(VRH) to characterize the ecological stability and quantify the recovery rate through the years-after-harvesting(YAH).Methods Carbon pool compartmentalization of 14 different components was determined in 60 harvested and primary unmanaged forests during the first 18 YAH in Tierra del Fuego(Argentina). We compared them using uni-and multi-variate methods, relativizing the outputs with primary unmanaged *** We determined the effectiveness to retain carbon components in post-harvested stands under different retention strategies(aggregated vs. dispersed). The balance among carbon pool components changed between managed and unmanaged stands across the YAH, and was directly related to the impact magnitude. Aggregated retention improved the ecological stability of the harvested areas, where the below-ground components were more stable than the above-ground components. The recovery rate was directly related to the post-harvesting natural dynamics of the stands. The studied period was not enough to fully recover the C levels of primary unmanaged forests, but VRH showed advantages to increase the C pools in the managed *** Promoting VRH can improve sustainable forestry at the landscape level and in the long term, generating positive synergies with biodiversity and the provision of ecosystem services. This study provides important new insights into forest carbon management, in particular to setting standards in carbon projects and

关键词： Carbon reservoir Temperate forest Ecological stability Recovery rate Forest carbon management

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Evaluating physical changes of iron oxide nanoparticles due to surface modification with oleic acid

引用

Chinese Physics B 2020年第10期29卷 186-194页

作者： S Rosales N Casillas A Topete O Cervantes G González J A Paz M E Cano centro universitario de Ciencias Exactas e Ingenienas Universidad de GuadalajaraBlvd.Marcelino Garcia Burragan 1421C.P.44430GuadalajaraJaliscoMexico centro universitario de la Cienegu Universidad de GuadalajaraAv.Universidad 1115C.P.47820OcotlanJaliscoMexico centro universitario de Ciencias de In Salud Universidad de Guadalajara.Sierra Mojada 950C.P.44340GuadalajaraJaliscoMexico

The physical characterization of a colloidal system of superficially modified magnetic nanoparticles (MNPs) is presented. The system consists of oleic acid-coated iron oxide nanoparticles (OAMNP) suspended in water. A structural analysis is carried out by using standard physical techniques to determine the diameter and shape of the MNPs and also the width of the coating shell. The colloidal stability and the polydispersity index of this ferrofluid are determined by using Zeta potential measurements. Additionally, the magnetic characterization is conducted by obtaining the DC magnetization loops, and the blocking temperatures are determined according to the ZFC–FC protocol. Finally, the values of power absorption density P of the ferrofluid are estimated by using a magneto-calorimetric procedure in a wide range of magnetic field amplitude H and frequency f. The experimental results exhibit spherical-like shape of OAMNP with (20 ± 4) nm in diameter. Due to the use of coating process, the parameters of the magnetization loops and the blocking temperatures are significantly modified. Hence, while the uncoated MNPs show a blocking state of the magnetization, the OAMNP are superparamagnetic above room temperature (300 K). Furthermore, the reached dependence P versus f and P versus H of the ferrofluid with coated MNPs are clearly fitted to linear and quadratic correlations, respectively, showing their accordance with the linear response theory.

关键词： nanoparticles ferrofluid magnetic hyperthermia functionalization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection

引用

Journal of Intensive Medicine 2024年第1期4卷 81-93页

作者： Marie dejonckheere Massimo Antonelli Kostoula Arvaniti Koen Blot Ben CreaghBrown Dylan Wde lange Jan de Waele Mieke deschepper Yalim Dikmen George Dimopoulos Christian Eckmann Guy Francois Massimo Girardis despoina Koulenti Sonia labeau Jeffrey Lipman Fernando Lipovestky Emilio Maseda Philippe Montravers Adam Mikstacki JoseArtur Paiva Cecilia Pereyra Jordi Rello JeanFrancois Timsit Dirk Vogelaers Stijn Blot the Abdominal Sepsis Study(AbSeS)group on behalf of the Trials Group of the European Society of Intensive Care Medicine department of Internal Medicine and Pediatrics Faculty of Medicine and Health SciencesGhent UniversityGhentBelgium department of Anesthesiology Intensive Care and Emergency MedicineFondazione Policlinico Universitario A.Gemelli IRCCSRomeItaly UniversitàCattolica del Sacro Cuore RomeItaly Intensive Care Unit Papageorgiou University Affiliated HospitalThessaloníkiGreece department of Epidemiology and Public Health SciensanoIxellesBelgium Surrey Perioperative Anaesthetic Critical Care Collaborative Research Group(SPACeR) Royal Surrey County HospitalGuildfordUK department of Clinical and Experimental Medicine University of SurreyGuildfordUK department of Intensive Care Medicine University Medical Center UtrechtUniversity UtrechtUtrechtthe Netherlands department of Intensive Care Medicine Ghent University HospitalGhentBelgium Data Science Institute Ghent University HospitalGhentBelgium department of Anesthesiology and Reanimation Cerrahpasa School of MedicineIstanbul University-CerrahpasaIstanbulTurkey rd department of Critical Care “EVGENIDIO”HospitalNational and Kapodistrian University of AthensAthensGreece department of General Visceral and Thoracic SurgeryKlinikum Hannoversch-MuendenGoettingen UniversityGöttingenGermany Division of Scientific Affairs-Research European Society of Intensive Care MedicineBrusselsBelgium Anesthesia and Intensive Care department University Hospital of ModenaModenaItaly UQ Centre for Clinical Research Faculty of MedicineThe University of QueenslandBrisbaneQLDAustralia nd Critical Care department Attikon University HospitalAthensGreece department of Nursing Faculty of EducationHealth and Social WorkUniversity College GhentGhentBelgium Jamieson Trauma Institute The University of QueenslandBrisbaneQLDAustralia Nimes University Hospital University of MontpellierNimesFrance Critical Care department Hospital of the Interamerican Open University(UAI)Buenos AiresArgentina Surgical Critical Care Department of AnesthesiaHospital Universitario

Background:The AbSeS-classification defines specific phenotypes of patients with intra-abdominal infection based on the(1)setting of infection onset(community-acquired,early onset,or late-onset hospital-acquired),(2)presence or absence of either localized or diffuse peritonitis,and(3)severity of disease expression(infection,sepsis,or septic shock).This classification system demonstrated reliable risk stratification in intensive care unit(ICU)patients with intra-abdominal *** study aimed to describe the epidemiology of ICU patients with pancreatic infection and assess the relationship between the components of the AbSeS-classification and ***:This was a secondary analysis of an international observational study(“AbSeS”)investigating ICU patients with intra-abdominal *** patients with pancreatic infection were included in this analysis(n=165).Mortality was defined as ICU mortality within 28 days of observation for patients discharged earlier from the *** with mortality were assessed using logistic regression analysis and reported as odds ratio(OR)and 95%confidence interval(CI).Results:The overall mortality was 35.2%(n=58).The independent risk factors for mortality included older age(OR=1.03,95%CI:1.0 to 1.1 P=0.023),localized peritonitis(OR=4.4,95%CI:1.4 to 13.9 P=0.011),and persistent signs of inflammation at day 7(OR=9.5,95%CI:3.8 to 23.9,Plated(n=58,49.2%)without clinically relevant differences in microbial etiology between survivors and ***:In pancreatic infection,a challenging source/damage control and ongoing pancreatic inflammation appear to be the strongest contributors to an unfavorable short-term *** this limited series,essentials of the AbSeS-classification,such as the setting of infection onset,diffuse

关键词： Pancreatic infection Intensive care unit Mortality Intra-abdominal infection Sepsis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：