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Determination of delta-9-tetrahydrocannabinol content of cannabis seizures in Egypt

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Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 291-294页

作者： Ahmed M.A.Souleman Alaa El-Din M.Gaafar Omar M.Abdel-Salam Shaimaa A.ElShebiney Department of phytochemistry and Plant Systematic National Research CentreCairoEgypt Department of Photochemistry National Research CentreCairoEgypt Department of Toxicology and Narcotics National Research CentreCairoEgypt

Objective:To determine the delta-9-tetrahydrocannabinol(THC)content of cannabis seizures in ***:Unheated and heated extracts of cannabis seizures were prepared from the dried flowering tops and leaves(marijuana)or from the resin(hashish)and subjected to analysis using high performance liquid chromatography(HPLC).Results:The heated resin extract had the peak of THC in a relative ratio of 31.34%,while extracting the resin directly without heating contained only 18.34%of *** the other hand,marijuana showed minimum percentage of THC at 11.188% on heating and 9.55% without ***:These results indicate the high potency of the abused cannabis plant in the illicit Egyptian market.

关键词： Cannabis Hashish Marijuana THC High performance liquid chromatography

Two New Gallotannins from Pistacia weinmannifolia

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Chinese Chemical Letters 2000年第1期11卷 53-56页

作者： Ai Jun HOU Li Yan PENG Yan Ze LIU Zhong Wen LIN Han Dong SUN Laboratory of phytochemistry Kunming Institute of BotanyChinese Academy of SciencesKunming 650204 Department of phytochemistry Henan College of Traditional Chinese MedicieZhengzhou 450003

Two new gallotannins, pistafolins A (1) and B (2), were isolated from the leaf extract of Pistacia weinmannifolia. Their structures were determined by spectral methods.

关键词： Pistacia weinmannifolia Anacardiaceae gallotannin pistafolin A pistafolin B

Two New ent-Kaurane Diterpenoids from Isodon xerophilus

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Chinese Chemical Letters 2000年第9期11卷 795-798页

作者： Ai Jun HOU Hui YANG Bei JIANG Qin Shi ZHAO Yan Ze LIU Zhong Wen LIN Han Dong SUN Laboratory of phytochemistry Kunming Institute of BotanyChinese Academy of SciencesKunming 650204 Department of phytochemistry Henan College of Traditional Chinese MedicineZhengzhou 450003

Two new ent-kaurane diterpenoids, xerophilusin E (1) and xerophilusin F (2), were isolated from the leaves of Isodon xerophilus. Their structures were determined as 3, 20: 7, 20-diepoxy-ent-kaur-16-en-15-one and 7 beta, 14 beta, 20 (R)-trihydroxy-11 beta-acetoxy-7,20-cyclo-ent-kaur-16-en-6, 15-dione, respectively, by spectral methods and X-ray crystallographic analysis.

关键词： Isodon xerophilus Labiatae ent-kaurane diterpenoids xerophilusin E xerophilusin F

New Coumarins From Peacedanum Decursivum

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Chinese Chemical Letters 1999年第6期10卷 477-480页

作者： Nian Huan YAO Ling Yi KONG(Department of phytochemistry. China Pharmaceutical University. Nan-ling 210038) Department of phytochemistry China Pharmaceutical University Nanjing 210038 China

Four new Coumarins named Decursitin B, C, D. F have been isolated from traditional Chinese medicine - the root of Peacedanum decursivum. Their structures were elucidated by chemical evidences and spectral analysis.

关键词： Peacedanum decursivum decursitin B decursitin C decursitin D decursitin F

A New Azafluorenone Alkaloid from Alphonsea Monogyma

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Chinese Chemical Letters 1999年第8期10卷 671-672页

作者： Ning XIE Nian Yun YANG (Department of phytochemistry.China Pharmaceutical University Nanjing 210009) Department of phytochemistry China Pharmaceutical University Nanjing 210009 China

A new azafluorenone (onychine) alkaloid, 6,7-dimethoxy-5-hydroxy-onychine, was isolated from the stem and branch of Alphonsea monogyma. Its structure was established mainly on the basis of spectral analysis.

关键词： Alphonsea monogyma 6,7-dimethoxy-5-hydroxy-onychine

A New Chromone Glycoside from Bupleurum Chinense

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Chinese Chemical Letters 1998年第1期9卷 69-70页

作者： Hong LIANG Yu Ying ZHAO Ru Yi ZHANG (Department of phytochemistry, Beijing Medical University, Beijing 100083) Department of phytochemistry Beijing Medical University Beijing 100083 China

A new chromone glycoside, saikochromoside A(1), was isolated from the roots of Bupleurum chinense DC. Its structure was determined on the bases of chemical and spectral analyses.

关键词： Bupleurum chinense DC saikochromoside A

The Diterpenoid Quinones from Coleus forskohlii

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Chinese Chemical Letters 2001年第4期12卷 339-342页

作者： Chun Suo YAO Yun Long XU Laboratory of phytochemistry Kunming Institute of BotanyAcademia SinicaKunming 650204

Two new diterpenoid quinones, colean S and T were isolated from the chloroform extract of the leaves of Coleus forskohlii, and based on spectroscopic data, their structures were identified as 1,4-phananthrenedione-4b,... 详细信息

关键词： Coleus forskohlii diterpenoid quinones Coleon S Coleon T.

Bougainvillea spectabilis flowers extract protects against the rotenone-induced toxicity

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Asian Pacific Journal of Tropical Medicine 2017年第5期10卷 457-466页

作者： Omar M.E.Abdel-Salam Eman R.Youness Nadia A.Ahmed Sayed A.El-Toumy Ahmed M.A.Souleman Nermeen Shaffie Dalia M.Abouelfadl Department of Toxicology and Narcotics National Research CentreCairoEgypt Department of Medical Biochemistry National Research CentreCairoEgypt Department of Chemistry of Tannins National Research CentreCairoEgypt Department of phytochemistry and Plant Systematic National Research CentreCairoEgypt Department of Pathology National Research CentreCairoEgypt

Objective:To investigate the effect of two extracts of Bougainvillea spectabilis(B. spectabilis) flowers with yellow and pink/purple on brain oxidative stress and neuronal damage caused in rats by systemic rotenone injection. Methods:Rotenone 1.5 mg/kg was given three times per week alone or in combination with B. spectabilis flowers extracts(25 mg or 50 mg) via the subcutaneous route for 2 weeks. Brain concentrations of the lipid peroxidation marker malondialdehyde(MDA),reduced glutathione,nitric oxide(nitrite),the pro-inflammatory cytokine interleukin-1beta(Il-1β) as well as butyrylcholinesterase,and paraoxonase-1(PON-1) activities,were determined. Histopathology and caspase-3 immunohistochemistry were also performed. Results:Rotenone resulted in significant increases of brain MDA(the product of lipid peroxidation),and nitric oxide content along with decreased brain reduced glutathione. There were also marked and significant inhibition of brain PON-1 and BCh E activities and increased Il-1β in brain of rotenone-treated rats. B. spectabilis flowers extract itself resulted in brain oxidative stress increasing both lipid peroxidation and nitrite content whilst inhibiting PON-1 activity. The yellow flowers extract inhibited BCh E activity and increased brain Il-1β. When given to rotenone-treated rats,B. spectabilis extracts,however,decreased lipid peroxidation while their low administered doses increased brain GSH. Brain nitrite decreased by the pink extract but showed further increase by the yellow extract. Either extract,however,caused further inhibition of PON-1 activity while the yellow extract resulted in further inhibition of BChE activity. Histopathological studies indicated that both extracts protected against brain,liver and kidney damage caused by the toxicant. Conclusions:These data indicate that B. spectabilis flowers extracts exert protective effect against the toxic effects of rotenone on brain,liver and kidney. B. spectabilis flowers extracts decreased

关键词： Bougainvillea spectabilis Flowers Extract Rotenone Oxidative stress Parkinson’s disease

Two New Steroidal Saponins from Tacca plantaginea

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Chinese Chemical Letters 2002年第7期13卷 633-636页

作者： Hai Yang LIU Chang Xiang CHEN Laboratory of phytochemistry Kunming Insitute of BotanyChinese Academy of ScienceKunming 650204

Two new C27 steroidal glycosides, named taccaoside A (1) and B (2), were isolated from the traditional Chinese herb Tacca plantaginea. The spectroscopic and chemical evidences revealed their structures to be 26-O--D-glucopyranosyl-(25R)-3?26-dihydroxy furost-5,20-diene -3-O-[?L-rhamnopyranosyl(12)]-[?L-rhamnopyranosyl(13)]--D-glucopyranoside (1) and 26-O--D-glucopyranosyl-(25R)-3?26-dihydroxy furost-5,20-diene-3-O-[?L-rhamnopyranosyl- (12)]-[?D-glucopyranosyl(13)--L-rhamnopyranosyl(13)]--D-glucopyranoside (2), res- pectively.

关键词： Tacca plantaginea steroidal saponins taccaoside A and B.