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Petroleum Science 2024年第3期21卷 1683-1698页

作者： Bogdan Sebacher Remus Hanea Department of applied informatics Military Technical Academy “Ferdinand I” Equinor

The facies distribution of a reservoir is one of the biggest concerns for geologists, geophysicists, reservoir modelers, and reservoir engineers due to its high importance in the setting of any reliable decisionmaking/optimization of field development planning. The approach for parameterizing the facies distribution as a random variable comes naturally through using the probability fields. Since the prior probability fields of facies come either from a seismic inversion or from other sources of geologic information, they are not conditioned to the data observed from the cores extracted from the wells. This paper presents a regularized element-free Galerkin(R-EFG) method for conditioning facies probability fields to facies observation. The conditioned probability fields respect all the conditions of the probability theory(i.e. all the values are between 0 and 1, and the sum of all fields is a uniform field of 1). This property achieves by an optimization procedure under equality and inequality constraints with the gradient projection method. The conditioned probability fields are further used as the input in the adaptive pluri-Gaussian simulation(APS) methodology and coupled with the ensemble smoother with multiple data assimilation(ES-MDA) for estimation and uncertainty quantification of the facies distribution. The history-matching of the facies models shows a good estimation and uncertainty quantification of facies distribution, a good data match and prediction capabilities.

关键词： Element free Galerkin (EFG) Adaptive pluri-Gaussian simulation (APS) Facies distribution estimation Ensemble smoother with multiple data assimilation (ESMDA)

Selective nano-buckling improves the performance of graphene logic transistors

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National Science Review 2024年第2期11卷 95-96页

作者： Tong Yang Ming Yang Department of applied Physics The Hong Kong Polytechnic University Research centre for Nanoscience and Nanotechnology The Hong Kong Polytechnic University

The massive integration of silicon-based transistors into modern electronic devices greatly increases power consumption and heat generation/dissipation[1]. In this concern, transistors based on atomically-thin graphene that exhibit high electric and thermoelectric conductivities with negligible contact resistance,

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The immune system: uncharted pathways between senses and the brain

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Neural Regeneration Research 2024年第6期19卷 1173-1174页

作者： Noelia Casares Mar Cuadrado-Tejedor Ana García-Osta Juan José Lasarte Immunology and Immunotherapy Program Centre for Applied Medical Research (CIMA) University of NavarraIDISNA Division of Gene Therapy for Neurological Disorders Centre for Applied Medical Research (CIMA) University of NavarraIDISNA Pathology Anatomy and Physiology Department School of Medicine University of NavarraIDISNA

Humans and animals use the classic five senses-sight, hearing, touch, smell, and taste-to detect and monitor their environment, with the sense of position and movement often referred to as the sixth sense. The perception of external signals through the senses is essential to an organism’s survival, transmitting signals to the central nervous system(CNS) and prompting physiological changes in other biological systems. In addition to the direct effects of sense-induced mediators in the brain,

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Weathering and accumulation of trace elements in the soils of the Porali Plain, Balochistan: repercussions in agriculture

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Acta Geochimica 2024年第2期43卷 214-234页

作者： Maria Kaleem Erum Bashir Shahid Naseem Tahir Rafique Bushra Shahab Department of Geology University of KarachiKarachi 75270Pakistan applied Chemistry Research centre PCSIR Laboratories ComplexKarachi 75280Pakistan

This study is theﬁrst attempt to assess the nature of the soil,especially on the western side of the Porali Plain in Balochistan;a new emerging agriculture hub,using weathering and pollution indices supplemented by multi-variate analysis based on geochemical data.The outcomes of this study are expected to help farmers in soil manage-ment and selecting suitable crops for the region.Twenty-ﬁve soil samples were collected,mainly from the arable land of the Porali Plain.After drying and coning-quarter-ing,soil samples were analyzed for major and trace ele-ments using the XRF technique;sieving and hydrometric methods were employed for granulometric analysis.Esti-mated data were analyzed using Excel,SPSS,and Surfer software to calculate various indices,correlation matrix,and spatial distribution.The granulometric analysis showed that 76%of the samples belonged to loam types of soil,12%to sand type,and 8%to silt type.Weathering indices:CIA,CIW,PIA,PWI,WIP,CIX,and ICV were calculated to infer the level of alteration.These indices reﬂect mod-erate to intense weathering;supported by K_(2)O/AI_(2)O_(3),Rb/K_(2)O,Rb/Ti,and Rb/Sr ratios.Assessment of the geo-ac-cumulation and Nemerow Pollution indices pinpoint rela-tively high concentrations of Pb,Ni,and Cr concentration in the soils.The correlation matrix and Principal Compo-nent Analysis show that the soil in this study area is mainly derived from the weathering of igneous rocks of Bela Ophiolite(Cretaceous age)and Jurassic sedimentary rocks of Mor Range having SEDEX/MVT type mineralization.Weathering may result in the undesirable accumulation of certain trace elements which adversely affects crops.

关键词： Weathering indices Pollution indices Accumulation Repercussions Trace elements Multivariate analyses Porali Plain Balochistan

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Praseodymium metal nanorods as a 5-fluorouracil carrier

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Journal of Rare Earths 2024年第7期42卷 1328-1336页

作者： Varnitha Manikantan Govindaraj Sri Varalakshmi Ujma Ashapak Tamboli Archana Sumohan Pillai Aleyamma Alexander Anushka Lucas Bose Allben Akash Israel V.M.V.Enoch centre for Nanoscience and Genomics Karunya Institute of Technology and Sciences (Deemed University) Department of applied Chemistry Karunya Institute of Technology and Sciences (Deemed University)

Interest in metal nanoparticles as nanoscale drug-carrying vehicles has been increasing.In such an aspect,lanthanide metal nanoparticles are particularly intriguing.Herein,we report praseodymium nanoparticles as a novel anticancer therapeutic transporting agent.The material was made as a composite with the supramolecular host polymer,poly-β-cyclodextrin.The praseodymium nanorods were characterized using standard analytical techniques,including X-ray diffraction（XRD）,X-ray photoelectron spectroscopy（XPS）,and thermogravimetric analysis（TGA）.In addition,they were imaged using transmission electron microscopy.The nanostructures are a long rod-shaped material with 2.0±0.1 μm in length and 230±10 nm in width.The material shows a saturation magnetization value above 30 emu/g with a coercivity value of 130 Oe.The nanocarrier is freighted with the drug 5-fluorouracil,and the encapsulation efficiency is 76.09%.The drug release is continuous from the nanocarrier（polymer-containing praseodymium nanoparticles） and proceeds for above 250 h.The in vitro cytotoxicities of the blank nanocarrier and the 5-fluorouracil-loaded one are deduced by testing them on MCF-7 and Vero（non-cancerous） cell lines.The cytotoxicity on the cancerous cell lines is observed,whereas the noncancerous cells are unaffected.The IC50values on the cell lines are reported.

关键词： Anticancer activity Drug delivery Metal nanoparticles Poly-cyclodextrin Praseodymium Rare earths

Equilibrium Arrivals to Preemptive Queueing System with Fixed and Random Population Size

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Journal of the Operations Research Society of China 2024年第1期12卷 77-92页

作者： Julia Chirkova Vladimir Mazalov Institute of applied Mathematical Research Karelian Research Centre of RASPetrozavodsk185910Russia School of Mathematics and Statistics Qingdao UniversityQingdao266071ShandongChina

A single-server queueing system with preemptive access is considered.Each customer has one attempt to enter the system at its working interval[0,T].As soon as the customer request enters the system,the server immediately starts the service.But when the next request arrives in the system,the previous one leaves the system even he has not finished his service yet.We study a non-cooperative game in which the customers wish to maximize their probability of obtaining service within a certain period of time.We characterize the Nash equilibrium and the price of anarchy,which is defined as the ratio between the optimal and equilibrium social utility.Two models are considered.In the first model the number of players is fixed,while in the second it is random and obeys the Poisson distribution.We demonstrate that there exists a unique symmetric equilibrium for both models.Finally,we calculate the price of anarchy for both models and show that the price of anarchy is not monotone with respect to the number of customers.

关键词： Service system Preemptive priorities Strategic users Random number of players Optimal arrivals Kolmogorov backward equations Nash equilibrium Price of anarchy

Competitive Resource Allocation Among Urban Congestion Areas in a Modern Big City

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Journal of the Operations Research Society of China 2024年第1期12卷 133-153页

作者： Alexander Krylatov Anastasiya Raevskaya Institute of applied Mathematical Research of the Karelian Research centre of the Russian Academy of Sciences Petrozavodsk185910Russia Saint Petersburg State University Saint Petersburg199034Russia

The continuing growth of modern big cities leads to their spatial expansion and the emergence of new road connections and urban areas.Areas where large transportation flows of pedestrians,passengers,and drivers come together create demand points,which attract business companies that strive to allocate their resources in the most sought-after places.However,the law of supply and demand restrains companies from allocating all their resources solely in the most popular congestion areas since the more valuable an urban area,the higher the cost to be paid for a resource unit allocation there.As a result,companies act in a non-cooperative manner and try to minimize their own overall costs when allocating resources across available commercial areas in a big city.Non-cooperative behavior of companies leads to the problem of Nash equilibrium search in the game of competing entrepreneurs.In this paper,we study the corresponding resource allocation game under affine cost functions and obtain Nash equilibrium strategies in explicit form.These findings allow us to develop a simple procedure for computing Nash equilibria in the game of companies allocating their resources among urban congestion areas.The computational study demonstrates the dependence of the average price for resource allocation on the number of players and their resource volumes.The outcome of the paper contributes to flow theory and seems to be fresh and useful for managers.

关键词： Resource allocation Nash equilibrium Affine costs

Ferroptosis mediators vary in metabolic syndrome,type-2 diabetes,and hypercholesterolemia:A meta-analysis report

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Genes & Diseases 2024年第3期11卷 109-112页

作者： Indra Kundu Ashlesha Pande Tannishtha Das Susan Idicula-Thomas Biomedical informatics centre Indian Council of Medical Research-National Institute for Research in Reproductive and Child HealthMumbaiMaharashtra 400012India Department of Biotechnology St.Xavier's CollegeKolkataWest Bengal 700016India

Metabolic syndrome(MetS)is a complex disorder characterized by the coexistence of phenotypes such as obesity,hypertension,hyperglycemia,high triglyceride level,and low level of high-density lipoprotein cholesterol.Inflammation majorly driven by oxidative stress has an overarching role in obesity and IR-mediated mechanisms leading to Mets.Besides these factors.

关键词： obesity cholesterol diabetes

Hydrodynamic function and spring constant calibration of FluidFM micropipette cantilevers

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Microsystems & Nanoengineering 2024年第1期10卷 277-286页

作者： Attila Bonyár Ágoston G.Nagy Hans Gunstheimer Gotthold Fläschner Robert Horvath Department of Electronics Technology Faculty of Electrical Engineering and InformaticsBudapest University of Technology and EconomicsBudapestHungary Nanobiosensorics Laboratory Institute of Technical Physics and Materials ScienceCentre for Energy ResearchHUN-RENBudapestHungary Nanosurf AG Gräubernstrasse 12CH-4410 LiestalSwitzerland

Fluidic force microscopy(FluidFM)fuses the force sensitivity of atomic force microscopy with the manipulation capabilities of microfluidics by using microfabricated cantilevers with embedded fluidic channels.This innovation initiated new research and development directions in biology,biophysics,and material science.To acquire reliable and reproducible data,the calibration of the force sensor is crucial.Importantly,the hollow FluidFM cantilevers contain a row of parallel pillars inside a rectangular beam.The precise spring constant calibration of the internally structured cantilever is far from trivial,and existing methods generally assume simplifications that are not applicable to these special types of cantilevers.In addition,the Sader method,which is currently implemented by the FluidFM community,relies on the precise measurement of the quality factor,which renders the calibration of the spring constant sensitive to noise.In this study,the hydrodynamic function of these special types of hollow cantilevers was experimentally determined with different instruments.Based on the hydrodynamic function,a novel spring constant calibration method was adapted,which relied only on the two resonance frequencies of the cantilever,measured in air and in a liquid.Based on these results,our proposed method can be successfully used for the reliable,noise-free calibration of hollow FluidFM cantilevers.

关键词： spring cantilever function

Preface: The Special Issue on Dynamic and Networking Games

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Journal of the Operations Research Society of China 2024年第1期12卷 1-3页

作者： Hong-Wei Gao Vladimir Mazalov School of Mathematics and Statistics Qingdao University266071QingdaoShandongChina Institute of applied Mathematical Research Karelian Research Centre of RAS185910PetrozavodskRussia

Numerous game theory-based techniques to characterize agent behavior haveemerged in response to the swift advancements in technology,communications,indus-trial organization,economic integration,and international trade.There is a huge varietyof mathematical techniques used in game theory.The application of dynamic and net-working game techniques is the main topic of this special issue.Studying strategicinteractions between many decision-makers with dynamic and varied connections isthe focus of research in the game theory discipline of dynamic and networking games.This field of study examines how agents or people make choices in dynamic circum-stances and how those choices impact their overall outcomes and payoffs.

关键词： agent strategic advancement