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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 238-250页

作者： Yikui Liu Bing Huang Yang Lin Yonghong Chen Lei Wu Electrical and Computer Engineering Department Stevens Institute of TechnologyHobokenNJ 07030USA Midcontinent Independent System Operator Inc.CarmelIN 46032USA

In response to the increasing penetration of volatile and uncertain renewable energy,the regional transmission organizations(RTOs)have been recently focusing on enhancing the models of pump storage hydropower(PSH)plants,which are one of the key flexibility assets in the day-ahead(DA)and real-time(RT)markets,to further boost their flexibility provision *** by the recent research works that explored the potential benefits of excluding PSHs’cost-related terms from the objective functions of the DA market clearing model,this paper completes a rolling RT market scheme that is compatible with the DA ***,with the vision that PSHs could be permitted to submit state-of-charge(SOC)headrooms in the DA market and to release them in the RT market,this paper uncovers that PSHs could increase the total revenues from the two markets by optimizing their SOC headrooms,assisted by the proposed tri-level optimal SOC headroom ***,in the proposed tri-level model,the middle and lower levels respectively mimic the DA and RT scheduling processes of PSHs,and the upper level determines the optimal headrooms to be submitted to the RTO for maximizing the total revenue from the two *** case studies quantify the profitability of the optimal SOC headroom submissions as well as the associated financial risks.

关键词： Pump storage hydropower energy market state-of-charge(SOC) headroom market revenue tri-level problem

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A comprehensive study on IoT privacy and security challenges with focus on spectrum sharing in Next-Generation networks(5G/6G/beyond)

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High-Confidence Computing

High-Confidence Computing 2024年第2期4卷 33-49页

作者： Lakshmi Priya Rachakonda Madhuri Siddula Vanlin Sathya Department of Computer Science North Carolina A&T State UniversityGreensboro 27401USA Celona inc. San Francisco 95008USA

The emergence of the Internet of Things(IoT)has triggered a massive digital transformation across numerous *** transformation requires efficient wireless communication and connectivity,which depend on the optimal utilization of the available spectrum *** the limited availability of spectrum resources,spectrum sharing has emerged as a favored solution to empower IoT deployment and connectivity,so adequate planning of the spectrum resource utilization is thus essential to pave the way for the next generation of IoT applications,including 5G and *** article presents a comprehensive study of prevalent wireless technologies employed in the field of the spectrum,with a primary focus on spectrum-sharing solutions,including shared *** highlights the associated security and privacy concerns when the IoT devices access the shared *** survey examines the benefits and drawbacks of various spectrum-sharing technologies and their solutions for various IoT ***,it identifies future IoT obstacles and suggests potential research directions to address them.

关键词： Spectrum sharing IoT devices Security Privacy

Scanning transmission electron microscopy and atom probe tomography analysis of non-stoichiometry long-period-stacking-ordered structures in Mg-Ni-Y/Sm alloys

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Journal of Magnesium and Alloys 2024年第3期12卷 954-965页

作者： Yimeng Chen Manuel Legrée Jean-Louis Bobet Alexander Kvit CAMECA Instruments inc MadisonWI 53711USA ICMCB Universitéde BordeauxPessacCEDEX 33608France NIAC&Materials Science Department University of WisconsinMadisonWI 53706USA

The long-period-stacking-ordered(LPSO)structure affects the mechanical,corrosion and hydrolysis properties of Mg *** current work employs high angle annular dark field-scanning transmission electron microscopy(HAADF-STEM)and atom probe tomography(APT)to investigate the structural and local chemical information of LPSO phases formed in Mg-Ni-Y/Sm ternary alloys after extended isothermal *** on the alloying elements and their concentrations,Mg-Ni-Y/Sm develops a two-phase LPSO+α-Mg structure in which the LPSO phase contains defects,hybrid LPSO structure,and Mg ***-STEM and APT indicate non-stoichiometric LPSO with incomplete Ni_(6)(Y/Sm)_(8) *** addition,the APT quantitatively determines the local composition of LPSO and confirms the presence of Ni within the Mg bonding *** results provide insight into a better understanding of the structure and hydrolysis properties of LPSO-Mg alloys.

关键词： Magnesium alloys Long-range ordering Atom probe tomography(APT) STEM HAADF Hydrolysis properties.

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Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair

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Journal of Molecular Cell Biology 2024年第3期16卷 46-60页

作者： Katrina N.Estep John W.Tobias Rafael J.Fernandez Brinley M.Beveridge F.Brad Johnson Department of Pathology and Laboratory Medicine University of PennsylvaniaPhiladelphiaPA 19104USA Quantiative Biosciences Merck&Co.Inc.West PointPA 19486USA Penn Genomic Analysis Core University of PennsylvaniaPhiladelphiaPA 19104USA

Although mechanisms of telomere protection are well-defined in differentiated cells,how stem cells sense and respond to telomere dysfunction,in particular telomeric double-strand breaks(DSBs),is poorly ***,we report the DNA damage signaling,cell cycle,and transcriptome changes in human induced pluripotent stem cells(iPSCs)in response to telomere-internal *** engineer human iPSCs with an inducible TRF1-FokI fusion protein to acutely induce DSBs at *** this model,we demonstrate that TRF1-FokI DSBs activate an ATR-dependent DNA damage response,which leads to p53-independent cell cycle arrest in *** CRISPR–Cas9 to cripple the catalytic domain of telomerase reverse transcriptase,we show that telomerase is largely dispensable for survival and lengthening of TRF1-FokI-cleaved telomeres,which instead are effectively repaired by robust homologous recombination(HR).In contrast to HR-based telomere maintenance in mouse embryonic stem cells,where HR causes ZSCAN4-dependent extension of telomeres beyond their initial lengths,HR-based repair of telomeric breaks is sufficient to maintain iPSC telomeres at a normal length,which is compatible with sustained survival of the cells over several days of TRF1-FokI *** findings suggest a previously unappreciated role for HR in telomere maintenance in telomerase-positive iPSCs and reveal distinct iPSC-specific responses to targeted telomeric DNA damage.

关键词： telomeres telomerase alternative lengthening of telomeres pluripotent stem cells DNA damage double-strand breaks

Polymer transfer film formation from cryogenic to elevated temperatures

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Friction 2024年第9期12卷 2018-2032页

作者： Kian BASHANDEH Vasilis TSIGKIS Ahmad AMIRI Pixiang LAN Andreas A.POLYCARPOU J.Mike Walker’66 Department of Mechanical Engineering Texas A&M UniversityCollege StationTexas 77843USA ATSP Innovations Inc.HoustonTexas 77055USA Russell School of Chemical Engineering The University of TulsaTulsaOklahoma 74104USA Department of Mechanical Engineering The University of TulsaTulsaOklahoma 74104USA

This study reports on the tribological performance of aromatic thermosetting co-polyester(ATSP)and polyether ether ketone(PEEK)-based polymer composite coatings mixed with PTFE *** coatings were tested across a wide temperature range from−180 to 110℃ to simulate the environmental temperatures on Titan,Moon,and Mars,which are of particular interest for NASA’s future exploratory *** experimental setup was developed to conduct the pin-on-disk experiments under dry sliding conditions and extreme temperature and contact *** film formation and its characteristics were found to play significant roles in the tribological performance,and the characteristics of the film were *** XPS and SEM analysis indicated the increase of the PTFE content in the transfer film as the temperature decreased to cryogenic *** coefficient of friction did not follow a linear trend with temperature and was minimum at 110℃ and maximum at−180℃.ATSP coating showed superior performance with lower friction and unmeasurable wear at all temperatures,whereas PEEK coating exhibited maximum wear at 25℃ followed by−180,and 110℃.

关键词： transfer film cryogenic high temperature tribology space tribology polymer coating

Interworking between Modbus and internet of things platform for industrial services

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Digital Communications and Networks 2024年第2期10卷 461-471页

作者： Sherzod Elamanov Hyeonseo Son Bob Flynn Seong Ki Yoo Naqqash Dilshad JaeSeung Song Department of Convergence Engineering for Intelligent Drone Sejong UniversitySouth Korea SyncTechno inc South Korea Exacta Global Smart Solutions USA Coventry University UK

In the era of rapid development of Internet of Things(IoT),numerous machine-to-machine technologies have been applied to the industrial *** to the divergence of IoT solutions,the industry is faced with a need to apply various technologies for automation and *** fact leads to a demand for an establishing interworking mechanism which would allow smooth interoperability between heterogeneous *** of the major protocols widely used today in industrial electronic devices is ***,data generated by Modbus devices cannot be understood by IoT applications using different protocols,so it should be applied in a couple with an IoT service layer ***2M,a global IoT standard,can play the role of interconnecting various protocols,as it provides flexible tools suitable for building an interworking framework for industrial ***,in this paper,we propose an interworking architecture between devices working on the Modbus protocol and an IoT platform implemented based on oneM2M *** the proposed architecture,we introduce the way to model Modbus data as oneM2M resources,rules to map them to each other,procedures required to establish interoperable communication,and optimization methods for this *** analyze our solution and provide an evaluation by implementing it based on a solar power management use *** results demonstrate that our model is feasible and can be applied to real case scenarios.

关键词： Internet of things Interoperability Interworking Modbus oneM2M

Development of novel 5-FU modified siRNA against BCL-2 with enhanced efficacy and vehicle-free cellular uptake

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Genes & Diseases 2024年第1期11卷 23-25页

作者： Andrew Fesler Ga-Ram Hwang Jingfang Ju Department of Pathology Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA The Northport Veteran's Administration Medical Center NorthportNY 11768USA Curamir Therapeutics inc. WoburnMA 01801USA

One of the major obstacles for nucleic acid-based medicine is cellular uptake due to the concern of efficiencyand potential toxicity of the *** this work,we developed a novel approach to eliminate the need for a vehicle to allow for the cellular uptake of siRNA-based therapy with a unique modification strategy that also further enhances therapeutic *** discovery may be of great importance for the development of siRNA-based therapeutics as cellular uptake remains a critical *** this study,we have tested the potential of this modification strategy for siRNA using a siRNA that targets B-cell lymphoma-2(BCL-2).

关键词： eliminate uptake modified

Modeling displacement flow inside a full-length casing string for well cementing

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Petroleum Research 2024年第1期9卷 1-16页

作者： Hu Dai Ali Eslami Jason Schneider Gefei Liu Fred Schwering Pegasus Vertex Inc.USA Laval University Canada Sanjel Energy Services Canada Athabasca Oil Corporation Canada

While computer modeling of annular displacement efficiency is widely applied in cementing engineering,modeling the displacement flow inside a casing or drill string for cementing operations has received less *** predicting displacement efficiency inside a full-length pipe is desired by cementing engineers,the attempt of developing a model with both efficiency and accuracy faces *** to computer simulators for this purpose is *** with annular flow,the displacement flow inside pipe,although within a simpler geometry and without eccentricity effect,is not simpler in physics,modelling strategy and predictability,because a variety of flow patterns and flow instabilities can develop to create complicated fluid *** this paper,we present an integrated numerical model developed to simulate displacement flows inside a full-length pipe,which connects an existing annulus model to enable complete displacement simulations of cementing *** model uses three-dimensional grid to solve fluid concentrations with degrees of mixing,and incorporates flow instability detection and flow regime *** in cementing,the model accounts for effects of pumping rate,well inclination,pipe rotation,fluid densities,rheological parameters and *** computationally efficient model does not rely on high-resolution mesh as often required by conventional Computational Fluid Dynamics models,thus it is suitable to be implemented in a cementing software for daily use by well cementing *** methodology of the model is discussed in detail in this *** validate the model,we examine simulation results against experimental results obtained in our laboratory tests and CFD simulations;acceptable agreement is found under different testing *** also presented two case studies of real cementing jobs with cement evaluation logs compared to simulation results,showing that the model can predict consistent displacement efficie

关键词： Inside pipe displacement Displacement efficiency Numerical model Primary cementing Displacement flow

Applying Earth Observation Technologies to Economic Consequence Modeling:A Case Study of COVID‑19 in Los Angeles County,California

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International Journal of Disaster Risk Science 2024年第1期15卷 18-31页

作者： Fynnwin Prager Marina T.Mendoza Charles K.Huyck Adam Rose Paul Amyx Gregory Yetman Kristy F.Tiampo California State University Dominguez HillsCarsonCA 90747USA ImageCat Inc.Long BeachCA 90802USA University of Southern California Los AngelesCA 90015USA CIESIN–Center for International Earth Science Information Network Columbia UniversityPalisadesNY 10964USA Cooperative Institute for Research in Environmental Sciences(CIRES) University of Colorado BoulderBoulderCO 80309USA

Earth observation(EO) technologies,such as very high-resolution optical satellite data available from Maxar,can enhance economic consequence modeling of disasters by capturing the fine-grained and real-time behavioral responses of businesses and the *** investigated this unique approach to economic consequence modeling to determine whether crowd-sourced interpretations of EO data can be used to illuminate key economic behavioral responses that could be used for computable general equilibrium modeling of supply chain repercussions and resilience *** applied our methodology to the COVID-19 pandemic experience in Los Angeles County,California as a case *** also proposed a dynamic adjustment approach to account for the changing character of EO through longer-term disasters in the economic modeling *** found that despite limitations,EO data can increase sectoral and temporal resolution,which leads to significant differences from other data sources in terms of direct and total impact *** findings from this analytical approach have important implications for economic consequence modeling of disasters,as well as providing useful information to policymakers and emergency managers,whose goal is to reduce disaster costs and to improve economic resilience.

关键词： Computable general equilibrium models COVID-19 Disaster economic impacts Earth observation Economic consequence analysis Los Angeles County

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Effects of essential oils on economically important characteristics of ruminant species: A comprehensive review

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Animal Nutrition 2024年第1期16卷 1-10页

作者： Cara Wessels Wells Micro Bios Inc.

Essential oils derived from plants can provide biological impacts to livestock species. Scientific studies researching essential oils in livestock have investigated various essential oils for prevention and treatment of microbial infection and parasites as well as to enhance milk production, animal performance and rumen function. Despite the availability of several commercial products containing essential oils to promote animal health and production, the vast amount of essential oils, modes of application, and effective concentrations of the essential oils suggest there are more opportunities for essential oils to be utilized in commercial livestock production and veterinary medicine. The objective of this review is to contribute to the understanding of the value that essential oils can provide to the ruminant diet and to examine the biological impact of various essential oils on economically important production traits of ruminant species.

关键词： Essential oils Ruminant diet Non-antibiotic therapy