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Bipolar I disorder and expressed emotion of families: A cohort study in Japan

Open Journal of Psychiatry 2012年第4期2卷 258-261页

作者： Shinji Shimodera Yukiko Yonekura Sosei Yamaguchi Aoi Kawamura Masafumi Mizuno Shimpei Inoue Toshi A. Furukawa Yoshio Mino Department of Cognitive-Behavioral Medicine Kyoto University Graduate School of Medicine/School of Public Health Kyoto Japan Department of Neuropsychiatry Kochi Medical School Kochi University Kochi Japan Department of Neuropsychiatry Toho University School of Medicine Tokyo Japan Department of Psychiatric Rehabilitation National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan Department of Psychiatry Mino Clinic Okayama Japan Department of Social Welfare Kansai University of Social Welfare Hyogo Japan

The relationships between expressed emotion (EE) of the families and the course of bipolar disorder have been examined only in a limited number of cohort studies. No study has yet been reported from Asia. The subjects were 12 patients that had been diagnosed with bipolar I disorder according to DSM-IV and their 12 key family members. The families of the patients were interviewed using the Camberwell Family Interview (CFI) within 2 weeks of the admission of the patients, and their EE were evaluated. The patients were then followed up for 9 months after their discharge from the hospital. The patients were divided into a high-EE group and a low-EE group using the cut-off based on the number of critical comments (CC) and emotional overinvolvement (EOI), and the 9-month relapse risk was compared. When the subjects with 3 or more CC or an EOI score of 3 or more were regarded as the high-EE group, and the others as the low-EE group, the 9-month relapse risk was 100% (3/3) for the high EE group and 0% (0/9) for the low EE group. (Fisher’s exact test p = 0.005) EE based on the CFI appear to be correlated with relapse in bipolar I disorder in Japan.

关键词： Expressed Emotion Family Bipolar Disorder

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Oral anti-coagulants use in Chinese hospitalized patients with atrial fibrillation

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Chinese Medical Journal 2024年第2期137卷 172-180页

作者： Jing Lin Deyong Long Chenxi Jiang Caihua Sang Ribo Tang Songnan Li Wei Wang Xueyuan Guo Man Ning Zhaoqing Sun Na Yang Yongchen Hao Jun Liu Jing Liu Xin Du Louise Morgan Gregg C.Fonarow Sidney C.Smith Jr Gregory Y.H.Lip Dong Zhao Jianzeng Dong Changsheng Ma On behalf of CCC-AF investigators Department of Cardiology Beijing Anzhen HospitalCapital Medical UniversityBeijing 100029China National Clinical Research center for Cardiovascular Diseases Beijing 100029 China Department of Epidemiology Beijing Anzhen HospitalCapital Medical UniversityBeijing Institute of HeartLung and Blood Vessel DiseasesBeijing 100029China International Quality Improvement Department American Heart AssociationDallasTX 07076USA Division of Cardiology Geffen School of Medicine at University of CaliforniaLos Angeles CA 90024USA Division of Cardiology University of North CarolinaChapel HillNC 27599USA Department of Cardiology Liverpool Centre for Cardiovascular ScienceUniversity of Liverpool and Liverpool Heart&Chest HospitalLiverpool L143PEUK Department of Clinical Medicine Aalborg UniversityAalborg 9000Denmark 不详

Background:Oral anti-coagulants(OAC)are the intervention for the prevention of stroke,which consistently improve clinical outcomes and survival among patients with atrial fibrillation(AF).The main purpose of this study is to identify problems in OAC utilization among hospitalized patients with AF in ***:Using data from the Improving Care for Cardiovascular Disease in China-Atrial Fibrillation(CCC-AF)registry,guideline-recommended OAC use in eligible patients was ***:A total of 52,530 patients with non-valvular AF were enrolled from February 2015 to December 2019,of whom 38,203 were at a high risk of stroke,9717 were at a moderate risk,and 4610 were at a low *** admission,only 20.0%(6075/30,420)of patients with a diagnosed AF and a high risk of stroke were taking *** use of pre-hospital OAC on admission was associated with a lower risk of new-onset ischemic stroke/transient ischemic attack among the diagnosed AF population(adjusted odds ratio:0.54,95%confidence interval:0.43-0.68;Pdischarge,the prescription rate of OAC was 45.2%(16,757/37,087)in eligible patients with high stroke risk and 60.7%(2778/4578)in eligible patients with low stroke *** utilization in patients with high stroke risk on admission or at discharge both increased largely over time(all Pdischarge was positively associated with in-hospital rhythm control strategies,including catheter ablation(adjusted odds ratio[OR]11.63,95%confidence interval[CI]10.04-13.47;P70%of AF patients were at a high risk of *** poor performance on guideline-recommended OAC use was found in this study,over time the CCC-AF project has made progress in stroke prevention in the Chinese AF ***

关键词： Atrial fibrillation Oral anti-coagulants OAC Stroke prevention Contraindication

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ST段抬高型急性冠状动脉综合征患者入院24h内接受他汀类药物治疗降低死亡率:首次欧洲心脏调查有关急性冠状动脉综合征的报道

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世界核心医学期刊文摘（心脏病学分册） 2007年第1期3卷 46-46页

作者： Lenderink T. Boersma E. Gitt A.K. M.L. Simoons 黄浙勇 Department of Cardiology Thoraxcentre Erasmus University Medical Center Dr Molewaterplein 40 3015 GD Rotterdam Netherlands

目的:他汀类药物为心血管疾病的二级预防用药,但急性冠状动脉综合征(ACS)患者该何时启用他汀类药物尚不确定。最近发表的临床试验建议出院前开始用药,而作者假设他汀类药物应尽早应用。方法与结果:对一大型队列研究中连续10848例ACS患... 详细信息

目的:他汀类药物为心血管疾病的二级预防用药,但急性冠状动脉综合征(ACS)患者该何时启用他汀类药物尚不确定。最近发表的临床试验建议出院前开始用药,而作者假设他汀类药物应尽早应用。方法与结果:对一大型队列研究中连续10848例ACS患者的资料进行分析。对其中第一时间接受他汀类药物治疗且发病24h后存活者1426例,与第1天后存活而未接受他汀类药物治疗的6771例患者进行比较。

关键词： ST段抬高他汀类药物欧洲心脏二级预防存活者心血管疾病队列研究临床试验第一时间早期治

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低密度脂蛋白≤800 mg/L的急性冠状动脉综合征患者应用他汀类药物治疗的效果

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世界核心医学期刊文摘(心脏病学分册) 2006年第4期 44-44页

作者： Tsai T.T. Nallamothu B.K. Mukherjee D. 王海玲 Department of Internal Medicine Division of Cardiology University of Michigan Medical Center Ann Arbor MI United States Dr.

We identified 155 patients who were admitted with an acute coronary syndrome and a low-density lipoprotein cholesterol level≤80 mg/dl and were not on statin therapy at hospital admission. The relation between statin therapy at discharge and clinical outcome was evaluated in these patients. Compared with patients wh o were not discharged on statins, those who were had a lower incidence of death, reinfarction, or stroke at 6 months(29.0%vs 9.5%, p=0.005). These results sug gest that patients who have an acute coronary syndrome and a low-density lipopr otein cholesterol level ≤80 mg/dl in the absence of statin therapy may benefit from such therapy at discharge.

关键词：急性冠状动脉综合征他汀类 mg/L 药物治疗患者

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吸烟控制对意大利急性心肌梗死住院率的短期效应

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世界核心医学期刊文摘（心脏病学分册） 2007年第3期3卷 58-58页

作者： Barone-Adesi F. Vizzini L. Merletti F. Richiardi L. 黄浙勇 Cancer Epidemiology Unit CeRMS and Center for Oncologic Prevention Piemonte University of Turin Via Santena 7 10126 Turin Italy

目的:根据意大利北部Piedmont地区的出院记录评估国家法律禁止公共场所吸烟的政策是否导致因急性心肌梗死(AMI)的住院短期内减少。方法和结果:分析禁令颁布前(2004年10月至12月)和实施期间(2005年2月至6月)的AMI住院情况,每个时期均与1... 详细信息

目的:根据意大利北部Piedmont地区的出院记录评估国家法律禁止公共场所吸烟的政策是否导致因急性心肌梗死(AMI)的住院短期内减少。方法和结果:分析禁令颁布前(2004年10月至12月)和实施期间(2005年2月至6月)的AMI住院情况,每个时期均与12个月前的相应时期进行比较。

关键词：急性心肌梗死住院率出院记录住院情况意大利北部短期效应实施期间禁止吸烟被动吸烟大样本

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丙型肝炎患者因乙醇相关问题入院的指标结果

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世界核心医学期刊文摘（胃肠病学分册） 2006年第5期2卷 50-50页

作者： Tsui J.I. Pletcher M.J. Vittinghoff E. 刘丽娜 Division of General Medicine San Francisco Veteran Administration Medical Center University of California 4150 Clement Street San Francisco CA 94121 United States

Background/Aims: Alcohol is known to act synergistically with chronic hepatitis C virus (HCV) infection to cause liver disease; however, their combined effect on outcomes in acutely hospitalized patients is less clear. We examined the impact of HCV infection on hospital mortality and length of stay among hospitalized patients with alcohol abuse problems. Methods: We retrospectively identified 6354 admissions to an urban, public hospital between July 1996 and January 2002 with discharge diagnoses related to alcohol dependence or abuse. Hepatitis C diagnosis and other information were extracted from a clinical database and tested for associations with death and length of hospital stay using multivariable regression techniques. Results: The prevalence of diagnosed HCV infection in this sample of patients with alcohol abuse was 15% . patients with HCV were about twice as likely to die during hospital admission (4.4 vs. 2.4% ; P-valueservice, homelessness and comorbidities (fully adjusted OR 1.41; 95% CI: 0.97-2.04). Length of stay was significantly longer for patients with HCV (19% longer; 95% CI: 12-27% after adjustment) than those without. Conclusions: patients admitted to the hospital with alcohol-related diagnoses have longer hospital stays and are more likely to die in hospital if they have a diagnosis of HCV.

关键词：丙型肝炎患者入院期慢性丙型肝炎病毒感染乙醇住院死亡率城市公立医院住院时间试验调查病毒感染后临床数据库

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缺血性卒中患者入院时钙水平升高是否与良好预后相关?

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世界核心医学期刊文摘(神经病学分册) 2006年第12期 22-22页

作者： Ovbiagele B. Liebeskind D.S. Starkman S. 郭俊 Dr.B.Stroke center Department of NeurologyUniversity of California at Los Angeles710 Westwood PlazaLos AngelesCA 90095United States

Calcium(Ca2+)and magnesium(Mg2+)influence the molecular pathways of ischemic neuronal *** authors evaluated the impact of admission serum Ca2+and Mg2+levels,on incident stroke severity and discharge functional *** adjusting for covariates,higher admission Ca2+was significantly associated with lesser stroke severity and better discharge functional *** Mg2+was not an independent clinical outcome prognosticator.

关键词：功能预后 Ga

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院内开展的卒中二级预防治疗方案在随访中有较高的坚持率

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世界核心医学期刊文摘（神经病学分册） 2005年第5期1卷 58-58页

作者： Ovbiagele B. Saver J.L. Fredieu A. 高方 Stroke center Department of Neurology Univ. of California at Los Angeles 710 Westwood Plaza Los Angeles CA 90095 United States Dr.

Background and Purpose -The Stroke PROTECT (Preventing Recurrence Of Thromb oembolic Events through Coordinated Treatment) program systematically implements , at the time of acute transient ischemic attack (TIA) or ischemic stroke admiss ion, 8 medication/behavioral secondary prevention measures known to improve outc ome in patients with cerebrovascular disease. The objective of this study was to determine if the high utilization rates previously demonstrated at hospital dis charge were maintained at 90 days after discharge. Methods -Data were prospect ively collected on consecutively encountered ischemic stroke and TIA patients ad mitted to a university hospital stroke service beginning September 1, 2002. PROT ECT interventions were initiated before hospital discharge in all PROTECT-targ et (underlying stroke mechanism large vessel atherosclerosis or small vessel dis ease) and PROTECT-ACS (At-risk for Coronary Sequelae) patients. Adherence to program goals was assessed 3 months after discharge. Results -During the peri od from September 2002 to August 2003, 144 individuals met criteria for PROTECT intervention. Of the 130 patients (90% ) with available day 90 follow-up data , mean age was 72 (range, 37 to 95), and 63% were male. Adherence rates in pat ients without specific contraindications were 100% for antithrombotics, 99% for statins, 92% for angiotensin-converting enzyme inhibitors/angiotensin re ceptor blockers, and 80% for thiazides. Awareness of the importance of calling 911 in response to stroke was 87% . Adherence to diet and exercise guidelines were 78% and 70% , respectively. Of the 24 smokers, tobacco cessation was mai ntained in 20 (83% ). Conclusions -High rates of adherence to PROTECT therapi es were maintained at 90 days after hospital discharge.

关键词：二级预防卒中发作短暂性缺血血栓事件抗血栓药噻嗪类利尿药血管粥样硬化血管疾病大学医院锻炼指导

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