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Biomedical and Environmental Sciences 2019年第1期32卷 38-41页

作者： YU Juan LI Hong LU Nan Nan LEI You Ju JIANG Shuang Ying ZHAO Sheng Cang RAO Hua Xiang center of hygiene inspection Qinghai Center for Disease Control and Prevention Institute for Communicable Disease Control and Prevention Qinghai Center for Disease Control and Prevention

Human adenoviruses (HAdVs) belong to the genus Mastadenovirus, family Adenoviridae, and can cause respiratory tract and gastrointestinal tract infections, as well as ocular infections in humans[1]. Till date, a total of 84 unique genotypes of AdVs have been identified and classified as human Mastadenovirus species A to G, and specific types are often associated with certain clinical symptoms, epidemiological settings, and demographic risk groups[2]. Among these species, members of the species HAdV-B (HAdV-3, HAdV-7, HAdV-11, HAdV-16, HAdV-21, HAdV-34, HAdV-35, HAdV-50, etc), HAdV-C (HAdV-1, HAdV-2, HAdV-5, and HAdV-6), and HAdV-E (HAdV-4) have been generally associated with respiratory infections[3]. HAdV infections are mild and self-limited in healthy individuals, whereas they can result in high mortality rates in immunocompetent and immunocompromized patients[4].

关键词： Human adenoviruses (HAdVs) mammivirus Eye infection

Bartonella Species Detected in the Plateau Pikas(Ochotona curzoiae) from Qinghai Plateau in China

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Biomedical and Environmental Sciences 2015年第9期28卷 674-678页

作者： RAO Hua Xiang YU Juan GUO Peng MA Yong Cheng LIU Qi Yong JIAO Ming MA Zhong Wen GE Hua WANG Chun Xiang SONG Xiu Ping SHI Yan LI Dong Mei Institute for Communicable Disease Control and Prevention Qinghai Center for Disease Control and Prevention center of hygiene inspection Qinghai Center for Disease Control and Prevention State Key Laboratory of Infectious Disease Prevention and Control Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and Prevention

Bartonella species can infect a variety ofmammalian hosts and cause a broad spectrum ofdiseases in humans, but there have been no reportsof Bartonella infection in Ochotonidae. This is thefirst study to detect Bartonella in plateau pikas inthe Qinghai plateau, providing baseline data for therisk assessment of human Bartonella infection inthis area. We obtained 15 Bartonella strains from79 pikas in Binggou and Maixiu areas of Qinghaiwith a positive rate of 18.99%. Based on thephylogenetic analysis of the Bartonella citratesynthase （gltA） gene sequences, most strains wereclosely related to B. taylorii （3/15） and B. grahamii（12/15）. The latter is a pathogenic strain in *** results suggest that a corresponding preventionand control strategy should be taken intoconsideration in the Qinghai province.

关键词： from Qinghai Plateau in China Ochotona curzoiae

Pathogenic Surveillance of Foodborne Illness-Related Diarrhea—Beijing Municipality,China,2013-2023

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China CDC weekly 2024年第24期6卷 568-573页

作者： Chao Wang Tongyu Wang Yanlin Niu Yangbo Wu Jinru Jiang Xiaochen Ma Institute for Nutrition and Food hygiene Beijing Center for Disease Prevention and ControlBeijingChina

What is already known about this topic?Foodborne diseases present a significant public health concern,particularly in China,where they represent a significant food safety ***,there is a need for a thorough and systematic analysis of the extended epidemiological patterns of foodborne diseases in Beijing *** is added by this report?Monitoring results show that Norovirus and diarrheagenic Escherichia coli(DEC)are the most commonly identified foodborne diarrheal *** aged 19–30 are at a higher risk of foodborne diarrhea in Beijing,with Salmonella infection being associated with fever *** are the implications for public health practice?This study analyzes 11 years of consecutive monitoring data to enhance understanding of the epidemiological and clinical features of foodborne diarrhea in *** aims to identify high-risk populations,assist in clinical pathogen identification and treatment,and support the development of tailored preventive strategies.

关键词： Beijing safety borne

Primary functional identification of gene TMSG-1

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Science China(Life Sciences) 2003年第6期46卷 641-650页

作者：马春树宁钧宇由江峰柳林王洁良崔湘琳吴秉铨郑杰 Department of Pathology Health Science Center Peking University Beijing 100083 China Analysis center of Medicine and hygiene Health Science Center Peking University Beijing 100083 China

TMSG-1 was a tumor metastasis-related gene identified using mRNA differential dis-play, whose expression level was lower in cancer cell lines with higher metastatic potential and in tumor tissue with metastasis. TMSG-1 was transfected to prostate cancer cell line (PC-3M-1E8) with high metastatic potential to observe the effects of increased expression of TMSG-1 on V-ATPase activity, intracellular pH and cell apoptosis. Subcellular localization of the encoded pro-tein of TMSG-1 was determined by using GFP. Results showed that there were no differences of V-ATPase activity among parental PC-3M-1E8 cell line, pcDNA3 transfectant and anti-TMSG-1 transfectant, whereas the V-ATPase activity was significantly higher in TMSG-1 transfectant than that in parental PC-3M-1E8 cell line, pcDNA3 transfectant and Anti-TMSG-1 transfectant (p<0.001). Intracellular pH (pHi) was detected by using the pH-dependent fluorescence probe BECEF. Re-sults showed the pHi was significantly increased in TMSG-1 transfectant. Cell apoptosis assay demonstrated cell apoptosis was significantly higher in -1 transfectant (p<0.01) and BCL2 expres-sion was down regulated. Subcellular localization of TMSG-1 protein showed TMSG-1 was a transmembrane protein, which predicted TMSG-1 protein was located in cytoplasm system, such as endoplasmic reticulum and mitochondrial. These results indicated TMSG-1 up regulation in prostate cancer cell line could promote V-ATPase activity, increase pHi and cell apoptosis, and inhibit the expression of BCL2.

关键词： prostate cancer, gene transfection, pH, apoptosis.

Molecular Characterization of Human Respiratory Adenoviruses Infection in Xining City, China In 2018

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Virologica Sinica 2021年第3期36卷 545-549页

作者： Juan Yu Shengcang Zhao Huaxiang Rao Department of Basic Medical Sciences Changzhi Medical CollegeChangzhi 046000China Department of Public Health and Preventive Medicine Changzhi Medical CollegeChangzhi 046000China center of hygiene inspection Qinghai Center for Disease Control and PreventionXining 810007China Institute for Communicable Disease Control and Prevention Qinghai Center for Disease Control and PreventionXining 810007China

Dear Editor,Adenoviruses are non-enveloped,double-stranded DNA viruses belonging to the Adenoviridae *** date,100unique genotypes of adenoviruses have been identified,from species A to G,could cause respiratory tract,... 详细信息

关键词： Human stranded envelope

Integrated nuclear techniques for sedimentation assessment in Latin American region

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International Soil and Water Conservation Research 2020年第4期8卷 406-409页

作者： JoséLuis Peralta Vital Reinaldo Honorio Gil Castillo Yanna Llerena Padrón Yusleidy Milagro Cordovi Miranda Naymi Labrada Arevalo Leroy Alonso Pino Environmental Impact Assessment Group Center of Radiation Protection and HygieneLa HabanaZip Code 10600Cuba

The paper shows the novel techniques introduction in the region of Latin America and the Caribbean in order to strengthen the surveillance and monitoring of the sedimentation phenomenon in the surface water *** integrated use of the nuclear techniques allows a more complete assessment of water and land *** the development of a regional project,supported by the International Agency of Atomic Energy,Cuba participates as technical leader for 15 countries,to encourage and implement the integrated application of 3 nuclear techniques(Fallout Radionuclides(137Cs,7Be,210pb),Compound Specific Stable Isotopes(fatty acids of the(e)13C)and the Isotopic Hydrology(18O,2H,3H).The methodology used in the last studies referred to RLA 5076 Project is to apply the integration of these three techniques allows evaluating,in the hydraulic facilities and surface water reservoirs,the negative sedimentation impacts in natural and anthropic process as environmental and social *** techniques evaluate the sedimentation process and its synergy,obtaining since the soil quantification in the landscape,definition the soil origin deposited until the dynamic characterization of the water body as soil *** integrated application of these nuclear techniques in the Project RLA-5076 confirms it as a useful tool to support the decisions makers in the definition of the national strategies and programs related to the land and the water resources *** the support of the IAEA projects in the Latin American and Caribbean region,has been evidenced an important increment in the use of these novel techniques.

关键词： Nuclear technique Sedimentation Water reservoir Soil Land Hydric resources

Prevalence of Thyroid Nodules and Its Relationship with Iodine Status in Shanghai:a Population-based Study

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Biomedical and Environmental Sciences 2016年第6期29卷 398-407页

作者： SONG Jun ZOU Shu Rong GUO Chang Yi ZANG Jia Jie ZHU Zhen Ni MI Ming HUANG Cui Hua YU Hui Ting LU Xi RUAN Ye WU Fan Department of Nutrition hygiene Shanghai Municipal Center for Disease Control and Prevention Department of Food hygiene & Food-Borne Disease Control Shanghai Municipal Center for Disease Control and Prevention Department of Health Statistics Shanghai Municipal Center for Disease Control and Prevention Department of School Health Shanghai Municipal Center for Disease Control and Prevention Department of Diabetes Mellitus Control and Prevention Shanghai Municipal Center for Disease Control and Prevention

Objective This study was designed to evaluate the prevalence of thyroid nodules（TNs） and its relationship with urine iodine concentrations（UICs） after the regional rapid economic growth and lifestyle changes. Methods A cross-sectional survey was conducted in the general population aged 15-69 years. A questionnaire regarding general and personal characteristics and relevant information was administered. Ultrasonography of the thyroid was performed, and serum triiodothyronine（T3）, tetraiodothyronine（T4）, serum thyroid stimulating hormone（TSH）, free triiodothyronine（FT3）, free tetraiodothyronine（FT4）, thyroglobulin antibody（Tg Ab）, thyroid peroxidase antibody（TPOAb）, and TSH receptor antibody（TRAb） levels were measured for each individual subject. Results The prevalence rates of TNs in the whole population, females and males were 27.76%, 34.04%, and 21.60%, respectively. The prevalence of multiple nodules increased with age, whereas the prevalence peaks differed between males and females. The median UICs in the whole population and females with non-TNs were higher than those of subjects with TNs（P=0.0035, P=0.0068）. The median UICs in subjects with a single TN were higher than those in subjects with multiple TNs（P=0.0164, P=0.0127）. The result showed a U-shaped curve relationship between UIC and prevalence of TNs. The prevalence of TNs was the lowest when the UIC was 140-400 μg/L. Conclusion The prevalence of TNs was nearly 30% and increased with age. The relationship between UIC and prevalence of TNs is U-shaped, with an increase in risk when the UIC was 〈140 μg/L and 〉400 μg/L. Very low or high UIC levels need attention and correction.

关键词： Thyroid Nodules Prevalence Urine iodine Epidemiology

Dietary Patterns Associated Metabolic Syndrome in Chinese Adults

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Biomedical and Environmental Sciences 2015年第5期28卷 370-373页

作者： HE Deng Hua YANG Min ZHANG Rong Hua MA Xiao Guang HUANG Li Chun HUANG En Shan GU Wei ZHU Yi Bo ZHAO Dong ZHU Xu Hui DING Gang Qiang ZHOU Biao Department of Nutrition and Food hygiene Medical School of Ningbo University Department of Nutrition and Food hygiene Zhejiang University School of Public Health Zhejiang Provincial center for Disease Control and Prevention

Dietary pattern has been revealed to be associated with metabolic syndrome. However, the association was not well documented in Chinese due to the complexity of Chinese foods. We mainly assessed the dietary patterns and examined their effects on metabolic syndrome among Chinese adults. Four dietary patterns including ＇Refined Grains ＆ Vegetables＂ Pattern, ＇Dairy ＆ Eggs＇ Pattern, ＇Organ Meat ＆ Poultry＇ Pattern, and ＇Coarse Grains ＆ Beans＇ Pattern were extracted. ＇Dairy ＆ Eggs＇ Pattern was associated with a decreased odds of metabolic syndrome in women, and ＇Coarse Grains ＆ Beans＇ Pattern was associated with a decreased odds of hypertension in men. These results provided a scientific basis for future research and dietarv euideline Perfection.

关键词： Dietary Patterns Associated Metabolic Syndrome in Chinese Adults FBG HDL

Drinking Behavior and Associated Factors among Middle School Students in Shanghai,China

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Biomedical and Environmental Sciences 2015年第10期28卷 765-768页

作者： WANG Zheng Yuan SONG Jun ZANG Jia Jie HUANG Cui Hua ZOU Shu Rong MA Guan Sheng Department of Nutrition hygiene Shanghai Municipal Center for Disease Control and Prevention National Institute for Nutrition and Health Chinese Center for Disease Control and Prevention

The purpose of our study was to assess drinking status in middle school students and to understand the associated factors. The adjusted drinking rates were 50.9%, 39.8%, and 15.1% for lifetime, past-year, and current ... 详细信息

关键词： School Drinking Behavior and Associated Factors among Middle School Students in Shanghai,China

The environmental influences on the bacteriological quality of red and chicken meat stored in fridges

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Asian Pacific Journal of Tropical Biomedicine 2017年第4期7卷 367-372页

作者： Hossein Masoumbeigi Hamid Reza Tavakoli Valiollah Koohdar Zohreh Mashak Ghader Qanizadeh Health Research center Baqiyatallah University of Medical Sciences Department of Food hygiene Karaj BranchIslamic Azad University

Objective: To investigate the environmental influences on the bacteriological quality of red and chicken meats on ***: The environmental health status was determined by reliable and valid researcher-made *** 264 samples were gathered in two phases(at the entrance and three months later) and examined for total bacteria count, Escherichia coli,Staphylococcus aureus and Salmonella ***: The result revealed that the mean of total bacteria count, *** and *** densities had significant differences in two steps on chicken and the red meat samples(P hygiene had significant effects on total bacteria count and *** densities in chicken samples(P hygiene).Regular control, improving of sanitary health, and staff training are necessary for elimination of bacterial contamination.

关键词： Fridges Environmental health Meat Chicken Bacteriological Quality control