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Dietary supplementation of laminarin improves the reproductive performance of sows and the growth of suckling piglets

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Journal of Animal science and Biotechnology 2024年第1期15卷 329-343页

作者： Pengguang Zhang Guoyuan Jiang Chenghong Ma Yubo Wang Enfa Yan Linjuan He Jianxin Guo Xin Zhang Jingdong Yin State Key Laboratory of Animal Nutrition and Feeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China

Background Maternal nutrition is essential in keeping a highly efficient production system in the pig *** has been shown to improve antioxidant capacity,reduce the inflammatory response,and favor the homeostasis of intestinal ***,the effect of dietary supplementation of laminarin on the reproductive performance of sows and the growth of suckling offspring remains *** A total of 40 Landrace×Yorkshire multiparous sows on d 85 of gestation,similar in age,body weight(BW),parity and reproductive performance,were randomly divided into four dietary treatments with 10 sows per treatment,receiving a control diet(basal pregnancy or lactating diets)and a basal diet supplemented with 0.025%,0.05%and 0.10%laminarin,*** experiment lasted from d 85 of gestation to d 21 of *** Laminarin supplementation linearly increased number born alive per litter(P=0.03),average daily feed intake(ADFI,P<0.01),and total milk yield of sows during the lactation of 1–21 d(P=0.02).Furthermore,maternal laminarin supplementation increased the average daily gain(ADG)of piglets while tending to reduce the culling and death rate before *** addition,alterations to the composition of colostrum and milk,as well as to serum inflammatory cytokines and immunoglobulins of sows were *** fecal microbiota profile of sows supported the improvement of reproductive performance in sows and the growth performance in suckling *** Dietary supplementation of laminarin during late pregnancy and lactation could significantly improve reproductive performance of sows and growth performance of piglets.

关键词： Fecal microbiota Laminarin Milk Piglets Reproductive performance Sows

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Single-atomic activation on ZnIn_(2)S_(4)basal planes boosts photocatalytic hydrogen evolution

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Nano Research 2024年第7期17卷 5949-5955页

作者： Jianpeng Cui Ying Wang Luxue Lin Xiaotian Yang Xuyu Luo Shiying Guo Xiaoyong Xu College of Physics science and technology and Center for Interdisciplinary ResearchYangzhou UniversityYangzhou 225002China

The use of single-atom cocatalysts plays a crucial role in enhancing artificial photocatalysis,where the precise construction of stable and efficient single-atom configuration is essential but remains ***,we report a simple one-step hydrothermal method for preparing single-atomic Mo modified ZnIn_(2)S_(4)(Mo-ZIS)nanosheets as a highly active photocatalytic hydrogen evolution(PHE)*** Mo substituting for portion of In atoms in ZIS nanosheets induces the spatial charge redistribution,which not only promotes the separation of photogenerated charge carriers but also optimizes the Gibbs free energy of adsorbing H*on S atoms at basal *** a result,Mo-ZIS exhibits an impressive PHE rate as high as 6.71 mmol·g^(−1)·h^(−1),over 10 times that of the pristine ZIS,with an apparent quantum efficiency(AQE)up to 38.8%at 420 *** study gains insights into the coordination configuration and electronic modulation resulting from single-atomic decoration,providing mechanistic cognitions for the development of advanced photocatalysts via non-precious metal atomic modification.

关键词： photocatalytic hydrogen evolution ZnIn_(2)S_(4) single-atom activation Gibbs free energy

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Oleanolic acid improved intestinal immune function by activating and potentiating bile acids receptor signaling in E. coli-challenged piglets

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Journal of Animal science and Biotechnology 2024年第5期15卷 2137-2155页

作者： Chenyu Xue Hongpeng Jia Rujing Cao Wenjie Cai Weichen Hong Jianing Tu Songtao Wang Qianzhi Jiang Chongpeng Bi Anshan Shan Na Dong The Laboratory of Molecular Nutrition and Immunity College of Animal Science and TechnologyNortheast Agricultural UniversityHarbinP.R.China

Background Infection with pathogenic bacteria during nonantibiotic breeding is one of the main causes of animal intestinal *** acid(OA)is a pentacyclic triterpene that is ubiquitous in *** previous work demonstrated the protective effect of OA on intestinal health,but the underlying molecular mechanisms remain *** study investigated whether dietary supplementation with OA can prevent diarrhea and intestinal immune dysregulation caused by enterotoxigenic Escherichia coli(ETEC)in *** key molecular role of bile acid receptor signaling in this process has also been *** Our results demonstrated that OA supplementation alleviated the disturbance of bile acid metabolism in ETEC-infected piglets(P<0.05).OA supplementation stabilized the composition of the bile acid pool in piglets by regulating the enterohepatic circulation of bile acids and significantly increased the contents of UDCA and CDCA in the ileum and cecum(P<0.05).This may also explain why OA can maintain the stability of the intestinal microbiota structure in ETEC-challenged *** addition,as a natural ligand of bile acid receptors,OA can reduce the severity of intestinal inflammation and enhance the strength of intestinal epithelial cell antimicrobial programs through the bile acid receptors TGR5 and FXR(P<0.05).Specifically,OA inhibited NF-κB-mediated intestinal inflammation by directly activating TGR5 and its downstream c AMP-PKA-CREB signaling pathway(P<0.05).Furthermore,OA enhanced CDCA-mediated MEK-ERK signaling in intestinal epithelial cells by upregulating the expression of FXR(P<0.05),thereby upregulating the expression of endogenous defense molecules in intestinal epithelial *** In conclusion,our findings suggest that OA-mediated regulation of bile acid metabolism plays an important role in the innate immune response,which provides a new diet-based intervention for intestinal diseases caused by pathogenic bacterial infections in pig

关键词： Bile acid receptors Enterotoxigenic Escherichia coli Intestinal innate immunity Oleanolic acid

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Answering reachability queries with ordered label constraints over labeled graphs

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Frontiers of Computer science 2024年第1期18卷 105-117页

作者： Daoliang HE Pingpeng YUAN Hai JIN National Engineering Research center for Big Data technology and System Services Computing Technology and System LabCluster and Grid Computing LabSchool of Computer Science&TechnologyHuazhong University of Science and TechnologyWuhan 430074China

Reachability query plays a vital role in many graph analysis *** researches proposed many methods to efficiently answer reachability queries between vertex *** many real graphs are labeled graph,it highly demands Label-Constrained Reachability(LCR)query inwhich constraint includes a set of labels besides vertex *** researches proposed several methods for answering some LCR queries which require appearance of some labels specified in constraints in the *** that constraint may be a label set,query constraint may be ordered labels,namely OLCR(Ordered-Label-Constrained Reachability)queries which retrieve paths matching a sequence of ***,no solutions are available for ***,we propose DHL,a novel bloom filter based indexing technique for answering OLCR *** can be used to check reachability between vertex *** the answers are not no,then constrained DFS is ***,we employ DHL followed by performing constrained DFS to answer OLCR *** show that DHL has a bounded false positive rate,and it's powerful in saving indexing time and *** experiments on 10 real-life graphs and 12 synthetic graphs demonstrate that DHL achieves about 4.8-22.5 times smaller index space and 4.6-114 times less index construction time than two state-of-art techniques for LCR queries,while achieving comparable query response *** results also show that our algorithm can answer OLCR queries effectively.

关键词： graph ordered-label-constrained reachability partial index bloom filter query processing

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Understanding the mechanism underlying the anti-inflammatory effect of dietary flavonoids on IBD: a focus on gut microbiota and its metabolites involved in SCFA， bile acid， tryptophan and lipopolysaccharides

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Food science and Human Wellness 2024年

作者： Huihui Xiong Hui Chen Lingli Chen Kehui Ouyang Suyun Lin Wenjun Wang College of Food science and Engineering， Jiangxi agricultural University College of Animal science and technology， Jiangxi agricultural University

Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease with a high incidence. Treatment for IBD includes medications and diet， and common anti-inflammatory medications have limitations like drug resistance and serious adverse effects. Accumulating evidence has demonstrated that dietary flavonoids exhibit an alleviative effect on IBD by influencing gut microbiota. The microbiota-derived metabolites also regulate IBD and maintain intestinal homeostasis. In this review， we investigate the therapeutic effect of gut microbiota and metabolites on IBD by intestinal immune and intestinal barrier function. We demonstrate the underlying mechanism of dietary flavonoids as an anti-inflammatory molecule alleviating IBD by regulating gut microbiota， short chain fatty acid (SCFA)， bile acid (BA)， tryptophan (Trp) metabolism and lipopolysaccharides (LPS)-toll-like receptor 4 (TLR4) signaling pathway. Based on structural differences of flavonoids， we summarize the recent research progress on the role of different dietary flavonoids in alleviating IBD by gut microbiota and metabolites in animal and clinical trials. This review indicates that dietary flavonoids targeting gut microbiota and metabolites provide a promising strategy for the treatment of inflammation and novel insights into the management of IBD.

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Growth,optical dispersion and magnetic behavior of Dy^(3+) doped yttrium iron garnet crystals

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Journal of Rare Earths 2024年第6期42卷 1110-1117,I0004页

作者： Yating Fang Hui Shen Yudie Ma Shijie Liao Shuang Xia Tian Tian Ding Zhou Yunfeng Ma Jiayue Xu Institute of Crystal Growth School of Materials Science and EngineeringShanghai Institute of Technology National Engineering center of Electromagnetic Radiation Control Materials School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of China

Y_(3)Fe_(5)O_(12)(YIG)crystals are highly desirable for the fabrication of mid-infrared isolators with the rapid growth of optical communications,although it is rather challenging to grow large size and high-quality single ***^(3+)doping is expected to improve the optical and magneto-optical prope ***,high quality Dy:YIG crystals and the adjustment of Dy^(3+)on the structure and optical behavior of YIG crystal remain unclear,impeding its practical ***,a series of Y_(3-x)Dy_(x)Fe_(5)O_(12)(x=0,0.5,1.0,1.5,3)solid solution crystals was grown by the flux-Bridgman method and single crystals up to 25 mm were *** the introduction of Dy^(3+),lattice parameters are gradually enlarged from 1.2379 nm(YIG)to 1.2420 nm(DyIG).Typical Dy^(3+)absorption peaks are observed around 1070,1265 and 1670 *** refractive index decreases from 2.37(500 nm)to 2.10(2500 nm)for YIG crystal,and it reduces from 2.47(500 nm)to 2.16(2500 nm)for DyIG *** optical bandgaps remain almost unchanged for Dy:YIG *** optical dispersion of the refractive indices was finely fitted by the Wemple and DiDomenico(WDD)and the Sellmeier models,*** the increase of Dy^(3+)content,the saturation magnetization(Ms)decreases significantly from 23.62 emu/g(YIG)to 5.33 emu/g(DyIG).Small coercive field is persisted for this system,endowing small external magnetic *** results provide valuable references for the manipulation of rare earths on the properties of magnetooptical crystals,which is beneficial to the design of high-performance garnet crystals for the application of optical switching and non-reciprocal related devices.

关键词： Magneto-optical crystal Yttrium iron garnet Dy^(3+)doping Crystal growth Optical dispersion Rare earths

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Striking a growth–defense balance:Stress regulators that function in maize development

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Journal of Integrative Plant Biology 2024年第3期66卷 424-442页

作者： Shiyi Xie Hongbing Luo Wei Huang Weiwei Jin Zhaobin Dong Maize Engineering and technology Research center of Hunan Province College of AgronomyHunan Agricultural UniversityChangsha 410128China State Key Laboratory of Maize Bio-breeding National Maize Improvement CenterFrontiers Science Center for Molecular Design BreedingChina Agricultural UniversityBeijing 100193China Tianjin Key Laboratory of Intelligent Breeding of Major Crops Fresh Corn Research Center of BTHCollege of Agronomy&Resources and EnvironmentTianjin Agricultural UniversityTianjin 300384China

Maize(Zea mays)cultivation is strongly affected by both abiotic and biotic stress,leading to reduced growth and *** has recently become clear that regulators of plant stress responses,including the phytohormones abscisic acid(ABA),ethylene(ET),and jasmonic acid(JA),together with reactive oxygen species(ROS),shape plant growth and *** their well established functions in stress responses,these molecules play crucial roles in balancing growth and defense,which must be finely tuned to achieve high yields in crops while maintaining some level of *** this review,we provide an in-depth analysis of recent research on the developmental functions of stress regulators,focusing specifically on *** unraveling the contributions of these regulators to maize development,we present new avenues for enhancing maize cultivation and growth while highlighting the potential risks associated with manipulating stress regulators to enhance grain yields in the face of environmental challenges.

关键词： stress regulators maize development ABA ET JA ROS

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Flow characterization of macroporous W-4.8 vol.%ZrO2 alloy during hot deformation with improved constitutive equation and processing maps

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Tungsten 2024年第3期6卷 610-620页

作者： Jia-Hao Ye Liu-Jie Xu Ji-Kang Hu School of Materials science and Engineering Henan University of Science and Technology National Joint Engineering Research center for Abrasion Control and Molding of Metal Materials Henan University of Science and Technology

In this work,isothermal compression experiments of macroporous W-4.8 vol.%ZrO2（W-4.8ZrO2） at 1300-1600℃ and strain rate of 0.005-1 s-1were carried out on a Gleeble-1500D thermo-mechanical *** dynamic recovery of W-4.8ZrO2is the main "softening" *** the basis of Arrhenius model,the initial constitutive equation is established by exploring the influence of temperature,strain rate and rheological *** on Arrhenius model,the relationship between flow stress,strain rate and deformation temperature is *** the influence of strain,the improved constitutive equation and the law of material constant changing with the strain are *** that,the hot processing maps were drawn on the basis of the dynamic material model,which is used to analyze the instability mechanism of the W-4.8ZrO2,and determine the appropriate hot working process parameters(temperature:1350-1450℃,strain rate:0.1-1 s-1).

关键词： Tungsten alloy Flow characteristics Constitutive equation Hot processing maps

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Non-Gaussian feature of the output field from a double qubit-cavity ultrastrong coupling system

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Communications in Theoretical Physics 2024年第7期76卷 30-36页

作者： Sheng-wen Xu Shi-yu Dai Teng Zhao center for Quantum science and technology Jiangxi Normal UniversityNanchang 330022China

We investigate the non-Gaussian feature of radiation in a circuit quantum electrodynamics(QED)system where two qubits are strongly coupled to a single-mode *** the regime of ultrastrong coupling(USC),the rotating-wave approximation is not valid,and the Rabi Hamiltonian contains counter-rotating wave terms,leading to level crossing and avoided crossings in the energy *** further analyze the intensity-amplitude correlation of the output field in these two novel *** the USC regime,the creation and annihilation operators in the correlation function are replaced,allowing for the identification of non-Gaussian features in the output *** findings reveal that despite the absence of squeezing effects in the output light,significant non-Gaussian characteristics are ***,we demonstrate that as the driving or coupling strength increases,the non-Gaussian features of the output field become more *** suggests that USC systems hold broad potential applications in the realms of nonlinear optics and the generation of non-Gaussian states.

关键词： ultrastrong coupling non-Gaussian intensity-amplitude correlation

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Efficient DIPA-CRISPR-mediated knockout of an eye pigment gene in the white-backed planthopper,Sogatella furcifera

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Insect science 2024年第4期31卷 1015-1025页

作者： Meng-Qi Zhang Lang-Lang Gong Ya-Qin Zhao Yun-Feng Ma Gui-Jun Long Huan Guo Xuan-Zheng Liu J.Joe Hull Youssef Dewer Chao Yang Ning-Ning Zhang Ming He Peng He National Key Laboratory of Green Pesticides Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationCenter for R&D of Fine Chemicals of Guizhou UniversityGuiyangChina Pest Management and Biocontrol Research Unit US Arid Land Agricultural Research CenterUSDA Agricultural Research ServicesMaricopaArizonaUSA Phytotoxicity Research Department Central Agricultural Pesticide LaboratoryAgricultural Research CenterDokkiGizaEgypt Guizhou Jifeng Seed Industry Limited Liability Company XingyiGuizhou ProvinceChina Shandong Facility Horticulture Bioengineering Research center Weifang University of Science and TechnologyWeifangShandong ProvinceChina

Although CRISPR/Cas9 has been widely used in insect gene editing,the need for the microinjection of preblastoderm embryos can preclude the technique being used in insect species with eggs that are small,have hard shells,and/or are difficult to collect and maintain outside of their normal *** is the case with Sogatella furcifera,the white-backed planthopper(WBPH),a significant pest of Oryza sativa(rice)that oviposits inside rice *** extraction from the stem runs the risk of mechanical damage and hatching is heavily influenced by the micro-environment of the rice *** bypass these issues,we targeted embryos prior to oviposition via direct parental(DIPA)-CRISPR,in which Cas9 and single-guide RNAs(sgRNAs)for the WBPH eye pigment gene tryptophan 2,3-dioxygenase were injected into the hemocoel of adult *** at varying numbers of days posteclosion were evaluated to determine at what stage their oocyte might be most capable of taking up the gene-editing *** evaluation of the offspring indicated that the highest G0 gene-edited efficacy(56.7%)occurred in females injected 2 d posteclosion,and that those mutations were heritably transmitted to the G1 *** study demonstrates the potential utility of DIPA-CRISPR for future gene-editing studies in non-model insect species and can facilitate the development of novel pest management applications.

关键词： CRISPR/Cas9 DIPA-CRISPR gene editing tryptophan 2,3-dioxygenase WBPH

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