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Comparative Study on Physical Activity in Diabetic and Non-Diabetic Individuals and Influential Factors—China,2020–2021

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China CDC weekly 2023年第45期5卷 1001-1005,I0001,I0002页

作者： Aolin Li Jun Lyu Yuanyuan Chen Zilun Shao Dianjianyi Sun Canqing Yu Liming Li Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Peking University center for public health and epidemic preparedness&response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina

Summary What is already known about this topic?The majority of Chinese patients with diabetes failed to achieve the level of physical activity recommended by clinical *** is added by this report?The prevalence of low-level physical activity was found to be greater in individuals diagnosed with *** was observed that patients with a protracted duration of diabetes demonstrated a propensity to participate in lower levels of physical activity compared to those with a shorter disease *** likelihood of engaging in low-level physical activity associated with diabetes was higher in rural inhabitants,those with medium-tier education,employed individuals,and individuals who had longer sleep *** are the implications for public health practice?Developing strategies and interventions to encourage greater involvement of Chinese diabetic patients in physical activity is ***,these strategies must take population characteristics into account.

关键词： Diabetic involvement shorter

Drawing on the Development Experiences of Infectious Disease Surveillance Systems Around the World

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China CDC weekly 2024年第41期6卷 1065-1074页

作者： Huimin Sun Weihua Hu Yongyue Wei Yuantao Hao Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Peking University center for public health and epidemic preparedness&response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina.

High-quality infectious disease surveillance systems are foundational to infectious disease prevention and *** major infectious disease surveillance systems globally can be categorized as either indicatorbased,which are more specific,or event-based,which are more *** surveillance systems commonly utilize multi-source data,strengthened information sharing,advanced technology,and improved early warning accuracy and *** experience may provide valuable insights for ***’s existing infectious disease surveillance systems require urgent enhancements to monitor emerging infectious diseases and improve the integration and learning capabilities of early warning *** such as establishing multi-stage surveillance systems,promoting cross-sectoral and cross-provincial data sharing,applying advanced technologies like artificial intelligence,and cultivating professional talent should be adopted to enhance the development of intelligent and multipoint-triggered infectious disease surveillance systems in China.

关键词： China strengthened utilize

Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching

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Neural Regeneration Research 2025年第9期20卷 2624-2632页

作者： Jangampalli Adi Pradeepkiran Priyanka Rawat Arubala P.Reddy Erika Orlov PHemachandra Reddy Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTXUSA Department of Nutritional Sciences College of Human SciencesTexas Tech UniversityLubbockTXUSA Department of Pharmacology&Neuroscience Texas Tech University Health Sciences CenterLubbockTXUSA Department of Neurology Texas Tech University Health Sciences CenterLubbockTXUSA Department of Speech Language and Hearing SciencesTexas Tech University Health Sciences CenterLubbockTXUSA Department of public health Texas Tech University Health Sciences CenterLubbockTXUSA

The process of neurite outgrowth and branching is a crucial aspect of neuronal development and *** and dendrites,sometimes referred to as neurites,are extensions of a neuron's cellular body that are used to start *** we explored the effects of diethyl(3,4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ)on neurite developmental features in HT22 neuronal *** this work,we examined the protective effects of DDQ on neuronal processes and synaptic outgrowth in differentiated HT22cells expressing mutant Tau(mTau)*** investigate DDQ chara cteristics,cell viability,biochemical,molecular,western blotting,and immunocytochemistry were *** outgrowth is evaluated through the segmentation and measurement of neural *** neural processes can be seen and measured with a fluorescence microscope by manually tracing and measuring the length of the neurite *** neuronal processes can be observed and quantified with a fluorescent microscope by manually tracing and measuring the length of the neuronal ***-treated mTau-HT22 cells(HT22 cells transfected with cDNA mutant Tau)were seen to display increased levels of synaptophysin,MAP-2,andβ-***,we confirmed and noted reduced levels of both total and p-Tau,as well as elevated levels of microtubule-associated protein 2,β-tubulin,synaptophysin,vesicular acetylcholine transporter,and the mitochondrial biogenesis protein-pe roxisome prolife rator-activated receptor-gamma coactivator-1α.In mTa u-expressed HT22 neurons,we observed DDQ enhanced the neurite characteristics and improved neurite development through increased synaptic *** findings conclude that mTa u-HT22(Alzheimer's disease)cells treated with DDQ have functional neurite developmental chara *** key finding is that,in mTa u-HT22 cells,DDQ preserves neuronal structure and may even enhance nerve development function with mTa u inhibition.

关键词： diethyl(3 4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ) hippocampal neuronal cells HT22 neurite outgrowth neuronal development small molecule

Development of China's health care system in the time of COVID-19:Challenges,opportunities,and call for actions

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health Care Science 2022年第1期1卷 33-40页

作者： Liming Li Department of Epidemiology and Biostatistics School of Public HealthPeking University Center for Public Health and Epidemic Preparedness&ResponsePeking UniversityBeijingChina

1|INTRODUCTION China has a population of over 1.4 *** the domestic expenditure made up only 8.8%of the general government expenditure in China(less than half of 19.7%in United Kingdom and 22.4%in the United States),and 22.3 medical doctors per 10,000 population in 2020,China's life expectancy at birth has been increased to 77.4 years,and neonatal mortality rate has been reduced to 3 per 1000 live births[1].After the founding of the People's Republic of China,a socialist healthcare system with Chinese characteristics was established and has made remarkable achievements.

关键词： healthcare management post-COVID public health

Variations in the Prevalence of Anemia of Varying Severity Among Urban Non-Pregnant Women—China,2021

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China CDC weekly 2024年第10期6卷 175-180页

作者： Xiaoxi Liu Bo Wang Sailimai Man Heling Bao Yuanyuan Huang Canqing Yu Jun Lyu Linhong Wang Liming Li Hui Liu Institute of Medical Information Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Peking University health Science center Meinian public health Institute BeijingChina Meinian Institute of health BeijingChina Peking University center for public health and epidemic preparedness&response BeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina National center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Anemia is a significant public health issue affecting women *** studies in China predominantly concentrated on anemia in pregnant or reproductiveage women,leaving a gap i... 详细信息

关键词： Anemia anemia China.

The Association Between Preserved Ratio Impaired Spirometry and Mortality –– 10 CKB Study Areas, China, 2004–2022

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China CDC weekly 2024年第43期6卷 1120-1125,I0003页

作者： Yalei Ke Xinyi Zhang Dianjianyi Sun Pei Pei Huaidong Du Yiping Chen Ling Yang Xiaoming Yang Kang Wang Junshi Chen Zhengming Chen Jun Lv Liming Li Canqing Yu Department of Epidemiology and Biostatistics School of Public HealthPeking University Health Science CenterBeijingChina Peking University center for public health and epidemic preparedness&response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK Shibei center for Disease Control and Prevention Qingdao CityShandong ProvinceChina China National center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina.

What is already known about this topic?China has the world’s most significant public health and economic burden of chronic respiratory ***,the association between preserved ratio impaired spirometry(PRISm)and mortality risk is *** is added by this report?The PRISm group exhibited a 37%higher risk of allcause mortality than the normal group,and the risks of death from cardiovascular diseases,neoplasms,respiratory diseases,and infectious and parasitic diseases were also increased in ***,the presence of respiratory symptoms or disease was associated with an increased risk of mortality in *** are the implications for public health practice?It is imperative to enhance public awareness of PRISm and to implement measures to facilitate the regression of PRISm toward normal lung function.

关键词： function impaired neoplasms

Key Social Determinants to Narrow the Gap between health-adjusted Life Expectancy and Life Expectancy in Megacities

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Biomedical and Environmental Sciences 2022年第9期35卷 773-781页

作者： XI Jun Yan CHEN Yuan Yuan ZHANG Yu Qin LUO Ao DU Zhi Cheng LIANG Bo Heng DONG Hang LIN Xiao QIN Peng Zhe HAO Yuan Tao Department of Medical Statistics School of Public HealthSun Yat-sen UniversityGuangzhou 510080GuangdongChina Department of Chronic Non-communicable Disease Control and Prevention Guangzhou Center for Disease Control and PreventionGuangzhou 510440GuangdongChina Institute for Infectious Disease Control and Prevention Guangdong Provincial Center for Disease Control and PreventionGuangzhou 511430GuangdongChina Peking University center for public health and epidemic preparedness&response Peking UniversityBeijing 100191China Sun Yat-sen Global health Institute Sun Yat-sen UniversityGuangzhou 510080GuangdongChina center for health Information Research Sun Yat-sen UniversityGuangzhou 510080GuangdongChina

Objective Improvement in the quality of life is reflected in the narrowing of the gap between healthadjusted life expectancy(HALE)and life expectancy(LE).The effect of megacity expansion on narrowing the gap is rarely *** study aimed to disclose this potential *** Annual life tables were constructed from identified death records and population counts from multiple administrative sources in Guangzhou,China,from 2010 to *** regression was used to evaluate the temporal *** principal component analysis and multilevel models were applied to examine the county-level association between the gap and social *** Although LE and HALE in megacities are increasing steadily,their gap is *** and health services are guaranteed to narrow this *** personal wealth,a growing number of newborns and healthy immigrants,high urbanization,and healthy aging have helped in narrowing this *** In megacities,parallel LE and HALE growth should be highly considered to narrow their *** social determinants need to be integrated as a whole to formulate public health plans.

关键词： Generalized principal component analysis health-adjusted life expectancy Megacities Quality of life Social determinants Temporal trend Urban expansion

Combination patterns of precipitation and its concentration degree determining the risk of dengue outbreaks in China

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Advances in Climate Change Research 2023年第5期14卷 768-777页

作者： Yu-Rong WU Xiao-Wen WANG Liang ZHAO Bo LU Jun-Feng YU Ze-Hua LIU Yi SUN Wan-Nian LIANG Cun-Rui HUANG School of public health Sun Yat-sen UniversityGuangzhou 510006China Vanke School of public health Tsinghua UniversityBeijing 100084China Shanghai Typhoon Institute China Meteorological Administration&Shanghai Key Laboratory of Meteorology and HealthShanghai Meteorological ServiceShanghai 200030China center for public health and epidemic preparedness&response Peking UniversityBeijing 100871China The State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China National Climate center China Meteorological AdministrationBeijing 100081China Institute of healthy China Tsinghua UniversityBeijing 100084China

The amount and distribution of precipitation can determine dengue risk by affecting mosquito breeding;however,previous studies failed to incorporate this bivariate characteristic to examine dengue fever *** the present research,nationwide data on daily dengue cases in China between January 2005 and December 2020 were obtained,and the top 12 cities accounting for 78%of total cases were selected for *** patterns were quantified by weekly precipitation and precipitation concentration degree(PCD).On the basis of the combinations of both parameters,the exposure-response relationships of precipitation with dengue risk were established using generalised additive models,and the high-dengue-risk thresholds of precipitation patterns were further *** burden was assessed by calculating attributable dengue *** the same amount of precipitation,the dispersed precipitation in the pre-summer rainy season leads to a higher dengue risk in *** weekly precipitation of 100-150 mm and PCD of 0.2-0.4 constitute the highest risk scenario,and the average frequency of precipitation associated with dengue risk in 2013-2020 is 1.6 times higher than that in 2005-2012.A total of 3093 attributable dengue cases are *** 2005 to 2020,the amount of dispersed precipitation increased in southern and southwestern China and posed high dengue risks in central *** study has improved the understanding of the health impacts of irregular rainfall under climate *** approach to identifying thresholds provides information for early warning systems and helps reduce the risk of dengue transmission in the long run.

关键词： Climate change Precipitation pattern Precipitation concentration degree Dengue fever Mosquito-borne diseases

Prevalence of anemia of varying severity, geographic variations, and association with metabolic factors among women of reproductive age in China: a nationwide, population-based study

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Frontiers of Medicine 2024年第5期18卷 850-861页

作者： Heling Bao Yuanyuan Huang Yi Sun Yunli Chen Yan Luo Liping Yan Sailimai Man Canqing Yu Jun Lv Meili Ge Linhong Wang Liming Li Bo Wang Hui Liu Xiaoxi Liu Institute of Medical Information Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100020China Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Meinian Institute of health Beijing 100044China Peking University health Science center Meinian public health Institute Beijing 100191China Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijing 100191China Peking University center for public health and epidemic preparedness&response Beijing 100191China Anaemia Diagnosis and Treatment center Institute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300052China National center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 100050China

To investigate the epidemiological characteristics of anemia of varying severity among women of reproductive age,we conducted a nationwide,cross-sectional study between January 1,2019 and December 31,2019,including 4184547 nonpregnant women aged 18–49 years from all 31 provinces in the mainland of *** was defined as having hemoglobin concentration<120.0 g/L and categorized as mild,moderate,and *** logistic models with cluster effect were used to explore the association of anemia and metabolic risk *** standardized prevalence of anemia and moderate and worse anemia among women of reproductive age in China was 15.8%(95%CI 15.1%–16.6%)and 6.6%(6.3%–7.0%),*** prevalence of anemia and the proportion of moderate and worse anemia significantly increased with *** also observed great geographic variations in the prevalence of anemia,with a high likelihood in south,central,and northwest *** and/or severe anemia was positively associated with overweight and obesity,diabetes,and impaired kidney *** conclusion,anemia remains a significant challenge for women of reproductive age in *** variations and metabolic risk factors should be considered in the comprehensive and targeting strategy for anemia reduction.

关键词： anemia prevalence women of reproductive age metabolic factor body mass index China