BACKGROUND AND PURPOSE-Although there is some Early evidence showing the value of repetitive transcranial magnetic stimulation(rTMS)in stroke rehabilitation,the therapeutic effect of high-frequency rTMS,along with the...
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BACKGROUND AND PURPOSE-Although there is some Early evidence showing the value of repetitive transcranial magnetic stimulation(rTMS)in stroke rehabilitation,the therapeutic effect of high-frequency rTMS,along with the physiology of rTMS-induced corticomotor excitability supporting motor learning in stroke,has not been *** study investigated high-frequency rTMS-induced cortical excitability and the associated motor skill acquisition in chronic stroke ***-Fifteen patients with chronic hemiparetic stroke(13 men;mean age 53.5 years)practiced a complex,sequential finger motor task using their paretic fingers either after 10 Hz or sham rTMS over the contralateral primary motor cortex(M1).Both the changes in the behavior and corticomotor excitability before and after the intervention were examined by measuring the movement accuracy,the movement time,and the motor-evoked potential(MEP)amplitude.A separate repeated-measures ANOVA and correlation statistics were used to determine the main and interaction effects as well as relationship between the changes in the behavioral and corticomotor ***-High-frequency rTMS resulted in a significantly larger increase in the MEP amplitude than the sham rTMS(P plastic change was positively associated with an enhanced motor performance accuracy(P plasticity and improve the motor learning performance in chronic stroke victims.
Understanding the behavior of matter at extreme pressures of the order of a megabar(Mbar)is essential to gain insight into various physical phenomena at macroscales—the formation of planets,young stars,and the cores ...
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Understanding the behavior of matter at extreme pressures of the order of a megabar(Mbar)is essential to gain insight into various physical phenomena at macroscales—the formation of planets,young stars,and the cores of super-Earths,and at microscales—damage to ceramic materials and high-pressure plastic transformation and phase transitions in *** dynamic compression of solids up to Mbar pressures,even a solid with high strength exhibits plastic properties,causing the induced shock wave to split in two:an elastic precursor and a plastic shock *** phenomenon is described by theoretical models based on indirect measurements of material *** advent of x-ray free-electron lasers(XFELs)has made it possible to use their ultrashort pulses for direct observations of the propagation of shock waves in solid materials by the method of phase-contrast ***,there is still a lack of comprehensive data for verification of theoretical models of different ***,we present the results of an experiment in which the evolution of the coupled elastic-plastic wave structure in diamond was directly observed and studied with submicrometer spatial resolution,using the unique capabilities of the x-ray free-electron laser(XFEL).The direct measurements allowed,for the first time,the fitting and validation of the 2D failure model for diamond in the range of several *** experimental approach opens new possibilities for the direct verification and construction of equations of state of matter in the ultra-high-stress range,which are relevant to solving a variety of problems in high-energy-density physics.
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