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A dry-electrode enabled ECG-on-Chip with arrhythmia-aware data transmission

Science China(Information Sciences) 2025年

作者： Xinzi XU Yanxing SUO Yang ZHAO Peiyi ZHOU Xiao HAN Qiao CAI Min WANG Jiajun YUAN Liebin ZHAO Yongfu LI Guoxing WANG Yong LIAN Department of micro-nano Electronics and MoE Key Lab of Artificial Intelligence Shanghai Jiao Tong University Pediatric AI Clinical Application and Research center Shanghai Engineering Research Center of Intelligence Pediatrics (SERCIP) Child Health Advocacy Institute Shanghai Children's Medical Center School of MedicineShanghai Jiao Tong University Shanghai Engineering Research center of Intelligence Pediatrics (SERCIP) Xin Hua Hospital Affiliate to Shanghai Jiao Tong University School of Medicine

Early detection and treatment of cardiovascular diseases (CVDs) can be significantly enhanced through the use of flexible wearable electrocardiogram (ECG) sensors, potentially reducing CVD-related mortality. This paper introduces an ECG-on-Chip (EoC) solution tailored for flexible ECG sensors, incorporating novel features to address common challenges in wearable ECG technology. The EoC integrates a chopper-stabilized capacitively-coupled instrumentation amplifier (CS-CCIA),ensuring a high common-mode rejection ratio (CMRR) and low noise performance. Performance is further boosted via a positive feedback loop (PFL) and a programmable gain amplifier (PGA) with shared on-chip calibration logic, which enhances input impedance and minimizes gain variability to ensure consistent algorithm performance. Additionally, a secondary chopping technique is employed to further reduce noise, achieving an input-referred noise level of 454 nVrms. The embedded algorithm within the EoC is designed to extract clinically meaningful features, facilitating robust real-time arrhythmia analysis. Fabricated using a 0.18μm CMOS process, the EoC consumes 14.9μW with a supply voltage of 1.2 V. The algorithm’s efficacy has been validated over 0.4 million heartbeats, demonstrating a sensitivity of over 99.7%for R-peak detection and 98.3%for arrhythmia analysis. To demonstrate practical application, the EoC has been integrated with a commercial Bluetooth low energy (BLE)transceiver, forming a wireless arrhythmia monitoring sensor equipped with dry electrodes. This system consumes 292.04μW in arrhythmia-aware transmission mode, supporting 13 days of operation with a 30 mAh thin-film battery.

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Effect of misfit strain on the electrocaloric effect of polydomain epitaxial ferroelectric thin films

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Chinese Physics B 2012年第9期21卷 489-494页

作者：邱建华丁建宁袁宁一王秀琴 center for Low-dimensional Materials Micro-nano Devices and SystemChangzhou University

The effect of misfit strain on the electrocaloric effect in polydomain epitaxial BaTi03 thin films at room temper- ature is investigated using the Ginzburg^Landau Devonshire thermodynamic theory. Numerical calculations indicate that the misfit strain has a large impact on the ferroelectric polarization states and the electrocaloric effect. Most importantly, the electrocaloric effect in the polydomain ca1/ca2/ca1/ea2 phase is much larger than that in the mon- odomain c phase and the other polydomain phases. Consequently, a large electrocaloric effect can be obtained by carefully controlling the misfit strain, which may provide potential applications in refrigeration devices.

关键词： polydomain electrocaloric effect phase transition

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Piezoelectric and electro optic properties of tetragonal(1-x)Pb(Mg_(1/3)Nb_(2/3))O_3-xPbTiO_3 single crystals by phenomenological theory

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Chinese Physics B 2015年第7期24卷 503-506页

作者：邱建华王秀琴袁宁一丁建宁 center for Low-dimensional Materials Micro-nano Devices and SystemChangzhou University

An eighth-order Landau–Devonshire theory is constructed to investigate the piezoelectric and electro–optic properties of tetragonal（1- x）Pb（Mg1/3Nb2/3）O3–xPbTiO3 single crystals（x = 0.38 and x = 0.4）. The dielectric stiffness coefficients of the Landau potential are obtained by fitting to the dielectric properties and the phase transition temperature between cubic phase and tetragonal phase. It is indicated that tetragonal（1- x）Pb（Mg1/3Nb2/3）O3–xPbTiO3 single crystals have the firstorder cubic-tetragonal phase transitions. The dielectric constants are in great agreement with the experimental *** piezoelectric coefficients d33 and d31at room temperature are about 145 p C/N and-62 p C/N respectively which are smaller than that of（1- x）Pb（Mg1/3Nb2/3）O3–xPbTiO3 single crystals around the morphotropic phase ***, tetragonal（1- x）Pb（Mg1/3Nb2/3）O3–xPbTiO3 single crystals have the linear electro–optic coefficients rc =33.7 pm/V and rc = 28.8 pm/V for x = 0.38 and x = 0.4, respectively which are in accordance with the measurements.

关键词： dielectric property piezoelectric property electrooptic effect

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Composition and misfit strain dependence of electrocaloric effect of Pb_(1-x) Sr_xTiO_3 thin films

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Chinese Physics B 2013年第1期22卷 504-508页

作者：邱建华丁建宁袁宁一王秀琴 center for low-dimensional materials micro-nano devices and system Changzhou University

A Landau-Devonshire thermodynamic theory is employed to investigate the effects of composition and misfit strain on the room-temperature electrocaloric effect of epitaxial Pbl-xSrxTiO3 thin films. The ＂temperature-misfit strain＂ phase diagrams with the Sr composition x of 0.1, 0.3, and 0.5 are constructed. The introduction of Sr composition reduces the Curie temperature greatly, and enhances the electrocaloric effect. Moreover, the electrocaloric effect largely depends on the misfit strain. Therefore, the Sr composition and the misfit strain can be controlled to obtain the giant room-temperature electrocaloric effect.

关键词： phase diagram phase transition electrocaloric effect

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可编程式自组装生长多色有机微米阵列（英文）

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Science China Materials 2025年

作者：张秋仪黄淇李建平岳晓飞盛晨旭 Husnain Jawad 周治国宋子洋解凤贤丛春晓仇志军胡来归刘冉 center of micro nano system School of Information Science and Technology Fudan University Institute for Electric Light Sources School of Information Science and Technology Fudan University College of Chemistry and Materials Science Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University Shanghai Key Lab of Chemical Assessment and Sustainability School of Chemical Science and Engineering Tongji University

具有不同像素类型的高分辨率有机阵列在各种领域中有着重要的应用前景,如全彩显示和光子晶体.通过传统工艺很难一步就制备出这类阵列(如高分辨率多色图案).在本工作中,我们提出了一种自下而上的溶液法,结合相变材料(特别是聚集诱导发光...

具有不同像素类型的高分辨率有机阵列在各种领域中有着重要的应用前景,如全彩显示和光子晶体.通过传统工艺很难一步就制备出这类阵列(如高分辨率多色图案).在本工作中,我们提出了一种自下而上的溶液法,结合相变材料(特别是聚集诱导发光材料).通过自组装过程,直接制备出了具有不同相或颜色的可编程微米级有机图案.值得注意的是,通过调整事先预定义的成核位点尺寸,实现了对成核和结晶物质的量的控制.这种精确调控可导致每个像素呈现不同的相和颜色.因此,直接实现了无需转移的具有多种颜色像素的高分辨率有机微米阵列,这为利用相变材料进行无需转移的多功能微图案生长开辟了道路,在高分辨率全彩成像/显示、光子晶体、信息存储、加密等领域有着巨大的潜力.

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Development of Raman acousto-optic frequency shifter based on SAW

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Journal of Semiconductors 2014年第8期35卷 104-109页

作者：王春梅温志渝张祖伟张颖异 Key Laboratory of Fundamental Science on micro/nano-Device and system Technology Chongqing University National center for International Research of micro/nano-system and New Material Technology Chongqing University microsystem Research center of Chongqing University

A Raman acousto-optic frequency shifter （AOFS） based on surface acoustic wave （SAW） is presented. It consists of a double-ended SAW resonator and optical waveguide system. The structure parameters of the SAW resonator are optimized using COM software and the optical waveguide system is designed using an effective index method. The AOFS prototype fabricated using MEMS technology is detected. The optical beat signals su- perimposed by ± 1st-order and ±2nd-order diffracted beams are detected. The frequency shift of 78.2201 MHz related to the 1 st-order diffracted beams and 156.2306 MHz related to the 2nd-order diffracted beams are obtained respectively.

关键词： SAW Raman AOFS frequency shift

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Calculation of surface acoustic waves in a multilayered piezoelectric structure

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Journal of Semiconductors 2013年第1期34卷 6-11页

作者：张祖伟温志渝胡晶 Key Laboratory of Fundamental Science on micro/nano-Device and system Technology Chongqing University National center for International Research of micro/nano-system and New Material Technology Chongqing University microsystem Research center Chongqing University

The propagation properties of the surface acoustic waves（SAWs） in a ZnO-SiO2-Si multilayered piezoelectric structure are calculated by using the recursive asymptotic *** phase velocities and the electromechanical coupling coefficients for the Rayleigh wave and the Love wave in the different ZnO-SiO2-Si structures are calculated and *** Love mode wave is found to be predominantly generated since the c-axis of the ZnO film is generally perpendicular to the *** order to prove the calculated results,a Love mode SAW device based on the ZnO-SiO2-Si multilayered structure is fabricated by micromachining,and its frequency responses are *** experimental results are found to be mainly consistent with the calculated ones,except for the slightly larger velocities induced by the residual stresses produced in the fabrication process of the *** deviation of the experimental results from the calculated ones is reduced by thermal annealing.

关键词： SAW RAM multilayered structure

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The fabrication of vibration energy harvester arrays based on AlN piezoelectric film

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Journal of Semiconductors 2013年第11期34卷 79-82页

作者：尚正国李东玲温志渝赵兴强 Key Laboratory of Fundamental Science on micro/nano-Device and system Technology Chongqing University National center for International Research of micro/nano-system and New Material Technology Chongqing University microsystem Research center of Chongqing University

： The fabrication and measurement results of the vibration energy harvester arrays based on the piezoelectric aluminum nitride （AlN） film are presented. The structure design and fabrication process of the device are introduced. The key material, the AIN film with crystal orientation （002）, was deposited by pulsed-DC magnetron sputtering and characterized by X-ray diffraction （XRD）. The resonant frequency, power out, and the open circuit voltage of the device are detected. The optimized load of 80 kΩ and a remarkable maximum power out of 30.4 μW are obtained when the acceleration of 0.9g （g is standard gravity acceleration） is applied. Key words： A1N; crystal orientation; harvester arrays; vibration energy

关键词： AlN crystal orientation harvester arrays vibration energy

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Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： Feng Zhang Chenyang Zhang Linlin Wu Wei Sun Hongliang Zhang Jianhua Chen Yong Pei Songjiang Li Engineering Research center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of micro&nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

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Influence of sputtering parameters on microstructure and mechanical properties of GeSbTe films

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中国有色金属学会会刊：英文版 2008年第1期18卷 167-170页

作者：付永忠 micro/nano Science and Technology center Jiangsu University

GeSb2Te4 films were deposited on Si substrates by RF magnetron sputtering,and the effects of sputtering power on the surface topography and anti-compression properties were studied with atomic force microscope(AFM)and ***,the mechanical properties of GeSb2Te4 films with oxygen impurity were also *** results indicate that proper sputtering power is important for obtaining GeSb2Te4 films with high compact structure and low surface roughness,which present good load-support *** the effect of oxygen impurity on the anti-compression properties of GeSb2Te4 films is not very significant as a whole,certain oxygen dosage can relax the internal stress,thereby the hardness of the films drops slightly.

关键词： GeSbTe薄膜溅射技术机械力学显微结构

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